A new study finds that the northeastern US coast will experience rapid sea-level rise due to global warming, posing significant threats to New York City and its surrounding areas. The expected rise of up to 8.3 inches could lead to flooding, submersion of low-lying land, and damage to ecosystems.
Researchers identified acyl CoA: monoacylglycerol acyltransferase 2 as a critical enzyme in fat absorption. In mice genetically modified to lack this enzyme, high-fat diets failed to induce obesity and related symptoms.
Phylonix received a broad US patent for its zebrafish-based assays to assess cardiac functions and toxicity. The company's eZ-ScreenTM technology enables thorough assessment of cardiotoxicity during early stages of drug development, leveraging the speed and cost-effectiveness of the zebrafish model.
Researchers have developed an organic material with high optical quality and strong ability to mediate light-light interaction, which can fill the slot between waveguides on integrated optical circuits. This innovation enables fast data processing in all-optical networks, potentially increasing internet speed.
Researchers at Georgetown University Medical Center have found that a class of Alzheimer's disease drugs may prevent long-term damage from traumatic brain injury (TBI) in animals. The study suggests that gamma secretase inhibitors, designed to prevent build-up of amyloid peptide, could potentially do so.
Researchers tracked viscosity changes in live cancer cells using a new Photodynamic Therapy drug. The results show that increased stickiness contributes to cell death, but also slows down the treatment's effect.
Scientists have developed a new technology to isolate dozens of HIV-specific antibodies from a single individual, allowing for the first time to study natural antibody-mediated HIV neutralization. This breakthrough may prove important in understanding how effective HIV-neutralizing antibodies arise during infection.
Researchers found that blocking dual leucine zipper kinase (DLK) gene may help prevent degeneration of ailing nerve cell branches, a potential trigger for painful neuropathy. The study could lead to the development of a drug to spare cancer patients considerable pain during chemotherapy.
University of Cincinnati researchers have identified a specific step in the biological chain of events leading to Diamond Blackfan anemia. They discovered that a ribosomal protein defect leads to abnormal activation of p53, causing premature death of red blood cells.
A recent study by Research Australia found that simple cooperation between agencies and local governments is crucial for good health care aid in the Solomon Islands. The research suggests that longer-term commitment and alignment of priorities are necessary to improve the health landscape in the region.
Researchers identified a common genetic sequence alteration that enhances the likelihood of acquiring a mutation in a gene linked to certain blood diseases. Patients with myeloproliferative neoplasms have a higher risk of developing another JAK2 mutation due to inherited DNA sequence changes.
Researchers in Colorado discovered a way to disrupt Pseudomonas aeruginosa biofilm formation by targeting protein and DNA with specific enzymes. This breakthrough could lead to improved treatment strategies for infections caused by this bacteria, which are prevalent in burns, wounds, and cystic fibrosis patients.
Researchers at Duke University Medical Center have documented a select group of children who achieved long-term tolerance after completing daily doses of peanuts as therapy for peanut allergies. The study showed that the body builds tolerance quickly, with key immunologic changes observed in these participants.
Researchers at Rockefeller University have identified a diverse team of antibodies in slow-progressing HIV patients whose coordinated pack hunting knocks down the virus. These natural antibodies, produced by six people infected with HIV, show limited neutralizing ability when alone but become effective when combined.