A meta-analysis of 12,294 patients found bevacizumab significantly increases the risk of gastrointestinal perforation, especially in those with advanced colorectal and renal cell cancers. The study also showed a dose-dependent relationship between bevacizumab dose and GI perforation risk.
Historians from Census of Marine Life reconstructed ocean life in olden days, revealing past sea life was teeming with over 27,000 southern right whales around New Zealand. The findings are causing authorities to revisit marine baselines and provide a new context for contemporary ocean management.
Researchers at Baylor College of Medicine have created a comprehensive library of clones covering most of the Drosophila melanogaster genome using the P[acman] tool. This new resource enables scientists to study large chunks of DNA in living flies, facilitating genetic research and discovery.
Researchers discovered that a pathogenic yeast species can complete a full sexual cycle despite lacking key reproductive genes. This phenomenon may play a role in the evolution of drug resistance and provides insights into chromosomal abnormalities.
Researchers at NIST have developed a laser ranging system that can pinpoint objects with nanometer precision over distances up to 100 kilometers. The novel LIDAR system combines the best of two approaches and features rapid updates from multiple reference points simultaneously every 200 microseconds.
A £4M funding award will support a multidisciplinary study combining stem cell science and tissue engineering to develop new treatments for bone fractures and orthopaedic problems. The research aims to improve our understanding of skeletal cell activity, scaffold development, and environmental factors that affect tissue regeneration.
Research finds that humans with diverse major histocompatibility complexes (MHCs) are more likely to choose mates with dissimilar MHCs, increasing genetic variability and immune system efficiency. This evolutionary strategy may help ensure healthy offspring and avoid endogamy.
Researchers at University of Western Ontario discovered that superbugs like Staphylococcus aureus can manipulate the immune system to prevent toxic shock syndrome. The study identifies a mechanism by which the bacteria bind to immune cells and produce an anti-inflammatory protein, allowing them to evade the host's defense.
A Monash-led research team has discovered a new link between disturbed blood flow and blood clotting, which is identified as the precise mechanism by which these changes activate the clotting process. This discovery may explain the lack of effectiveness of commonly used anti-clotting therapies.
A team of psychologists used videoconferencing technology to study how people adapt their head movements and facial expressions when conversing with someone of the opposite sex. They found that gender is not a determining factor in nonverbal communication, as people tend to mirror each other's movements regardless of the perceived gender.
A new study by the University of Kansas and Gallup indicates that people are naturally optimistic, with 89% expecting their next five years to be better than current life. Optimism is highest in Ireland, Brazil, Denmark, and New Zealand, but demography has a minimal impact on individual levels.