The CRESCENDO study found that rimonabant increased gastrointestinal, neuropsychiatric, and serious psychiatric side-effects compared to placebo. The primary endpoint of cardiovascular death, myocardial infarction, or stroke occurred at similar rates in both groups.
A study published in The Lancet found that specialist retrieval teams significantly reduce mortality rates among children transferred to pediatric intensive care units. Children admitted from other hospitals had better outcomes and lower mortality rates when transferred by specialist teams compared to non-specialist transfers.
A new study found that menstrual cramps can cause alterations in the brain's gray matter, even when pain is not present. Researchers discovered abnormal changes in specific brain areas involved in pain transmission and regulation, suggesting that the adolescent brain may be vulnerable to menstrual pain.
Researchers at the University of Minnesota have successfully treated children with recessive dystrophic epidermolysis bullosa, a fatal skin disease, using bone marrow stem cell therapy. The treatment has shown promising results, increasing collagen production and improving skin resistance to blister formation.
A pilot study found that reducing musculoskeletal pain by 20-30% is a key motivator for weight loss. The study, published in the journal Work, suggests that immediate health benefits can inspire overweight individuals to shed extra weight and commit to keeping it off.
Researchers are working to improve automatic speech recognition technology, aiming for a word-error rate of no more than 10 percent. A new multi-language audio database will be developed using publicly available sources like YouTube, featuring hundreds of speakers in English, Spanish, and Mandarin Chinese.
A new study found that while many with BDD seek cosmetic procedures, only two percent led to improved symptom reduction. The majority of patients continued to experience BDD symptoms despite treatment.
Researchers discovered significant structural changes and impaired left-ventricular function in the hearts of SMA mice, along with lower heart rates. Gene therapy approach showed promise in restoring heart rates and preventing dilated cardiomyopathy.
A $1.7 million NIH grant supports UT Dallas researcher Dr. Michael Kilgard's investigation into nerve stimulation as a long-term cure for tinnitus. The goal is to retrain the brain to ignore nerve signals that simulate ringing, offering a possible permanent end to the condition.
A new study found that about 75% of stroke patients continued taking their prescribed medications to prevent a second stroke three months after discharge. However, nearly 20% of patients stopped taking one or more of their medications due to various factors such as understanding and financial hardships.
A new study found that angry individuals pay more attention to rewarding images than threatening ones. This suggests that anger is associated with a motivation to approach rewards, rather than avoid threats. The research highlights the importance of understanding how emotions influence visual attention and behavior.
Researchers at U of Alberta have found a potential treatment for pulmonary hypertension by targeting the mitochondria in lung blood vessel cells. They discovered that dichloroacetate and trimetazidine can increase mitochondrial activity, inducing cell death and regressing the disease in animal models.
Researchers will study immune cells to identify biomarkers associated with TB infection and disease reactivation. The joint laboratory aims to develop early diagnosis and effective treatment for the highly contagious disease, affecting millions worldwide.
Research in Guinea reveals why chimpanzees attack humans, highlighting the importance of habitat conservation to prevent resource-based attacks. The team studied eleven attacks, finding that they occurred during periods of crop-raiding and food scarcity.
Scientists are deploying a 4-kilogram bubble chamber at SNOLab, Ontario, Canada to detect dark matter particles. The team hopes to establish evidence for dark matter using Weakly Interacting Massive Particles (WIMPS) and axions.
A new imaging technique, combining photoacoustic tomography and a smart contrast agent, produces three-dimensional images of melanoma with high accuracy. This enables surgeons to remove only the malignant tissue while maintaining clean margins.
Tropical Storm Dianmu made a quick track over South Korea and entered the Sea of Japan, with NASA's Aqua satellite capturing its infrared image. The storm is transitioning into an extra-tropical storm due to increasing vertical wind shear and cooler sea surface temperatures.
Researchers at the University of Leeds have developed an integrated system that stores excess energy and uses it to supply electricity during peak demand. This innovative system cuts greenhouse gas emissions by reducing nitrogen oxide emissions and capturing carbon dioxide in solid form for storage.
Donna Nelson, a University of Oklahoma professor, has been selected as a 2010 American Chemical Society Fellow for her contributions to the chemical sciences and outstanding service. She is recognized for her research on minorities in academe and functionalizing single-walled carbon nanotubes.
A team led by Drs. Michael A. Matthay and Jae W. Lee found that bone marrow stem cells secreted a protein that restored the lung barrier, preventing fluid and other elements from entering the lungs. The study suggests that this therapy may be a viable option for preventing respiratory failure in critically ill patients.
New research reveals that abnormal huntingtin protein plays a crucial role in neurogenesis, challenging previous understanding of its function in adult neurons. The study demonstrates htt's involvement in cell division and neurogenesis, shedding light on the pathogenic mechanisms underlying Huntington's disease.
A study found that infection with malaria parasites during antibiotic treatment developed a vaccine-like immunity against re-infection. Antibiotics can prevent malaria parasite replication in the liver, allowing the immune system to mount a robust defense against future infections.
Scientists have developed a substance to enhance visibility of skin cancer cells during scans, potentially leading to earlier detection and improved survival rates for patients with melanoma. The new technique uses photoacoustic tomography and a bioconjugated gold nanoparticle agent that targets skin cancer cells.
The University of Maryland will be the only academic institution in the US to possess a 950 MHz NMR spectrometer, enabling researchers to study large proteins and interactions with unprecedented resolution. The instrument will facilitate studies of protein assemblies, ubiquitin marking, and cellular function.
Researchers aim to mitigate radiation-induced gastrointestinal syndrome using stem cell-based therapies. The new grant will support the development of bone marrow transplant techniques and identify chemical agents that accelerate repair and regeneration of irradiated stem cells.
A recent study found Texas petrochemical emissions are down, but still significantly underreported. Researchers took airplane measurements to compare with industry inventories and found discrepancies in pollutant levels. The findings highlight the need for improved monitoring and regulation.
Assistant Professor Annelise Nguyen receives $370,000 grant to study cell communication in cancer cells, potentially leading to enhanced drug treatments. Her work also has potential applications for colon and prostate cancers.
A study of 53 overweight women found that consuming sugary drinks in moderation does not lead to weight gain or mood changes. Women instead reduced their voluntary energy intake elsewhere in the diet to balance the calories from the drinks.
Researchers have developed a method to prevent phthalates from migrating from PVC plastics, leading to safer products and reduced health risks. The approach permanently bonds plasticizers to the internal structure of PVC, suppressing migration and improving product durability.
A scientific study reveals that pouring champagne down the side of an angled glass preserves more carbon dioxide than pouring straight down the middle. The researchers also found that chilling champagne to 39 degrees Fahrenheit reduces carbon dioxide loss, making 'down-the-side' a winning method for preserving champagne's taste and fizz.
A recent study suggests that a new drug, Olaparib, can reduce tumor size in women with advanced hereditary ovarian and breast cancers, offering a promising targeted therapy approach. The Phase II trials showed significant shrinkage in tumor size and relatively mild toxicities.
Benjamin tenOever, a leading expert in microbiology and infectious diseases, has been awarded the 2010 ICAAC Young Investigator Award. His research focuses on understanding the cell's response to infection and developing novel strategies for vaccine and antiviral drug design.
Catherine A. Blish receives ICAAC Young Investigator Award for elucidating neutralizing antibodies in HIV transmission, sponsored by Merck. Her work shows that broad neutralizing antibody responses may not prevent superinfection with a second strain of HIV.
Researchers from Arizona State University analyzed fossilized animal bone fragments to find evidence of sharp-edged stones being used to remove flesh and marrow. This discovery pushes back the origins of technology and carnivory by 800,000 years.
Manuela Raffatellu, a UC Irvine researcher, received the 2010 ICAAC Young Investigator Award from ASM for her work on Salmonella typhimurium's interaction with the gut. Her research has identified novel roles for early T cell responses and IL-17 in preventing bacterial dissemination.
Researchers from Ohio State University have achieved the highest-resolution MRI scan of a magnet, revealing its magnetic properties at the nanoscale. This breakthrough could lead to advancements in data storage and biomedical imaging, as well as more efficient computer chips and devices.
Bernd Sturmfels received the John von Neumann Lecture for his work on applying algebraic ideas to problems in biology, statistics, optimization, and polynomial systems. The lecture surveyed recent applications of abstract algebra in modeling and solving nonlinear problems.
NASA's TRMM satellite confirms better organization in Tropical Depression 5, leading to its classification as the fifth tropical depression in the northeastern Gulf of Mexico. Forecasters predict strengthening into Tropical Storm Danielle in the next day or so.
A study by Trinity College Institute of Neuroscience found that people's brains respond differently to others' actions based on their perceived intentions. When generous behavior is framed as benefiting the group, participants showed a stronger neural response, indicating a greater liking for the action.
The Penn State College of Medicine has received a $54 million grant to act as the data coordinating center for the National Heart Lung and Blood Institute's AsthmaNet. The NHLBI Asthma Network will conduct multiple clinical trials to address key asthma management questions, with a focus on pediatric and adult populations.
UCF physicists analyze space dust using far IR spectroscopy to identify minerals and provide clues about solar system formation and life emergence. The findings will be published in the Monthly Notices of the Royal Astronomical Society journal.
The University of Leicester has developed an online diabetes risk assessment tool using 7 questions to identify those at high risk. The tool is being used in a number of studies to encourage people to see their doctor and has already been taken by over 21,000 individuals.
Scientists have discovered a new window into the Earth's violent past by analyzing geochemical evidence from volcanic rocks on Baffin Island. The study suggests that the primitive mantle, which dates back to just tens of millions of years after the Earth's formation, was already depleted in incompatible elements compared to chondrites.
Researchers found evidence for the oldest Earth mantle reservoir on Baffin Island, dating back to between 4.55 and 4.45 billion years ago. The discovery suggests an alternative to the traditional chondritic model of the Earth's composition.
Researchers have developed a model that confirms correlation between on and off periods in blinking phenomena, providing insights into the physical mechanism behind the vast range of emission times. The finding has potential applications in quantum dot imaging, cancer cell detection, and display screen development.
A NOAA study found that clouds exhibit oscillating patterns influenced by precipitation, creating regular rainfall events. The discovery highlights the impact of aerosols on large-scale cloud structure and climate change, suggesting a more complex understanding of interactions between aerosols and clouds.
Researchers have discovered over 100 new proteins involved in plant cell division, revealing the machinery behind this process for the first time. The newly developed Tandem Affinity Purification (TAP) Platform enables rapid unraveling of protein interactions, advancing crop yield optimization.
Scientists have developed a new approach to deliver therapeutic genes into brain cancer cells, using chlorotoxin from deathstalker scorpion venom and nanoparticles of iron oxide. This method has shown promise in inducing nearly twice the amount of gene expression in brain cancer cells compared to traditional approaches.
The new test uses mass spectrometry to analyze metabolites in a single drop of blood serum, accurately identifying women with ovarian cancer in all tested patients. Further testing will be conducted on 500 patients to confirm the results and explore its potential for detecting other types of cancers.
Researchers demonstrate how rain causes air movement that breaks down and builds up cloud walls, forming honeycomb clouds with self-organizing patterns. These clouds cycle regularly due to the interaction between rising and falling air, resulting in shifting showers over time.
A new study at McMaster University shows that using lighter weights can build muscle just as effectively as heavier ones. The key is to lift until fatigue sets in, pumping iron for a specific duration.
Dr. Binh An Diep, a researcher at the University of California, San Francisco, has made significant contributions to understanding methicillin-resistant Staphylococcus aureus (MRSA) epidemiology and pathogenesis.
A new study led by Ned H. Kalin of the University of Wisconsin-Madison School of Medicine and Public Health found that increased brain activity in the amygdala and anterior hippocampus can predict anxious temperament in young primates. This discovery may lead to new strategies for early detection and treatment of at-risk children.
A new study published in Neurology found that lithium is not effective in treating amyotrophic lateral sclerosis (ALS) due to a high dropout rate and serious side effects. The research involved 171 people with ALS, but showed no difference between those receiving therapeutic or subtherapeutic doses of lithium.
A recent study by The Wistar Institute found that the newly identified human adenovirus AdHu26 commonly infects people, particularly those in Sub-Saharan Africa, rendering it an unlikely candidate as a vaccine carrier. In contrast, chimpanzee adenoviruses demonstrate similar functionality and are considered superior for mass vaccination.
A USDA study uses near infrared light technology to quickly evaluate individual kernels of wheat and barley for resistance to scab disease. This allows breeders to rapidly select for resistant varieties, minimizing yield losses and promoting international food security.
A study by University of Alberta researcher Brea Malacad reveals shifting behaviors and attitudes towards oral sex among young women. The findings indicate that while some view oral sex as less intimate than intercourse, others see it as equally or more intimate. Additionally, the research highlights the need for sex educators to catch...
Carol Iversen received the 2010 ICAAC Young Investigator Award for her research on Enterobacter sakazakii taxonomy. Her work led to the creation of a new genus Cronobacter, which has improved detection and isolation of the bacteria.
The National Institutes of Health has launched a nationwide research initiative to define changes in the human immune system using human studies. The effort aims to improve vaccine safety, effectiveness, and overall therapeutic outcomes for various infections and diseases.
Dr. Thomas J. Walsh, Director of the Transplantation-Oncology Infectious Diseases Program at Weill Cornell Medical College, has been selected as the 2010 laureate of the sanofi-aventis ICAAC Award for his groundbreaking work on antifungal pharmacology and therapeutics.