Researchers at UH are studying 'wireless connections' in the brain to prevent diseases like epilepsy and schizophrenia. They found that liver X receptor β and thyroid hormone receptor α play key roles in brain development and regulation.
Celia has become the first major hurricane of the season in the Eastern Pacific, reaching Category Three strength with maximum sustained winds of near 115 mph. As she moves westward, Celia is expected to strengthen further today before weakening due to cooler sea surface temperatures.
The University of Delaware will receive a $10 million grant to establish a five-year research and development center aimed at understanding math difficulties in elementary and middle school children. Researchers plan to use a multidisciplinary approach to develop usable knowledge that will help students who are struggling in math.
A new study reveals that nearly every newborn has a new transposon insertion in their genome, suggesting a significant increase in genetic instability. Transposons are also implicated in tumor formation and can inactivate tumor suppressor genes.
Recent guidelines call for lower target blood pressure levels in CKD patients, but a critical review finds the data is not definitively supported by scientific evidence. The author suggests that doctors should make individualized decisions about blood pressure control for their patients with kidney disease.
A study published in Neuron reveals that the loss of Nna proteins causes mitochondrial dysfunction, leading to severe cell death in mice and fly models. Researchers believe this discovery could provide insights into human neurodegenerative disorders like Parkinson's disease.
A recent study published in Nature found that auxin and cytokinin, two previously thought-to-be antagonistic plant growth hormones, actually cooperate to regulate plant growth. The international team of researchers discovered that auxin boosts the effect of cytokinin by suppressing genes that limit its activity.
Researchers from Germany and the US developed a new synthesis paradigm for efficient hydrogen generation. The team found that the light wavelength used in the process affects its efficiency, with redder light resulting in better outcomes.
Researchers discovered that plants integrate information about food location and competitors to develop unique root growth strategies. This complexity is a level of sophistication previously thought exclusive to animals.
A team of MIT chemists has designed a new way to attach trifluoromethyl groups to compounds, which could allow pharmaceutical companies to create and test new drugs faster and more efficiently. The new synthesis uses a palladium catalyst and achieved yields ranging from 70 to 94 percent.
Researchers at LA BioMed developed a novel approach to efficiently identify disease-relevant genes in human complex neurological disorders. This method was successfully applied to Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's Disease, revealing new insights into the disease and potential diagnostic tests.
A new study suggests that restricting speculative trading in futures markets could destabilize commodity prices, rather than reduce volatility. The research found that the influx of cash from index traders provided a deep pool of liquidity that held price increases in check.
A meta-analysis of 34 studies involving 3962 patients found that brief cognitive behavior therapy (CBT), counseling, and problem-solving therapy (PST) were equally effective in treating depression and mixed anxiety. The study suggests that brief psychological therapies can be an effective treatment for routine delivery in primary care.
A recent study analyzed worldwide catch and economic data for the past 55 years, finding that fishermen prioritize profit over top predators. The research revealed that nearly all high-catch fisheries are already developed, with few new opportunities existing today.
Researchers identified two experimental drugs that harness the fight-or-flight response to restore pumping strength to failing hearts. By targeting a key protein, these compounds slow and halt the progression of heart disease.
A Texas A&M researcher has found that early mammalian embryos possess three stem cell lineages with different viral silencing strategies, including XEN cells that exhibit rapid and aggressive silencing of retroviruses. The study provides new insights into fetal diseases and has profound implications for diagnosis and treatment.
A new study at Wake Forest University Baptist Medical Center finds that cardiac MRI can reduce hospital admissions and costs for chest pain patients in the emergency department. The study uses cardiac MRI to provide accurate diagnostics in an observation unit, reducing unnecessary hospital stays.
Researchers at Thomas Jefferson University found that antiviral therapy prevents HCC recurrence and extends survival in CHB patients. The median survival was 60 months for those receiving antiviral therapy, compared to 12.5 months for those not receiving it.
A study published in the World Journal of Gastroenterology revealed endoscopic findings of CMV gastritis in seven patients after allo-SCT, with oozing, erosion, and redness more frequently documented in these cases. The researchers suggest using erosion and oozing as early markers for CMV gastritis diagnosis.
Using television and radio to tell stories about sustainable rice farming has helped Asian farmers better conserve biodiversity. Dr. K.L. Heong's research found that building biodiversity into rice paddies can prevent pest outbreaks, reducing the need for pesticides.
Scientists have monitored rapid faunal changes in a deep-sea community off Ireland's coast, where sea cucumber populations surged in abundance. Climate-driven fluctuations in organic matter supply and nutrient quality may have triggered these events.
Researchers have made significant progress in developing new medical technologies to combat the anthrax threat. Promising new treatments include a long-sought inhalable vaccine that can be self-administered without a needle, as well as new antibiotics and medicines that can block the effects of anthrax toxin.
NIST scientists have developed a theoretical model to decode electrical signals generated by nanopores, enabling the identification and quantification of proteins and other molecules. This breakthrough brings us closer to realizing nanopores as a powerful diagnostic tool for medical science.
Researchers at UNC Health Care have identified a simple, non-toxic pill that decreases radiation toxicity when given after radiation exposure. The drug, called PQ, temporarily stops bone marrow cells from dividing, protecting against radiation-induced damage.
A new synthetic molecule targeting non-nuclear estrogen receptors may activate cardiovascular benefits of estrogen without increasing cancer risk. The study suggests this approach could be beneficial for women, particularly those with high cholesterol and diseased arteries.
Researchers at Mount Sinai School of Medicine discovered that DNA polymerase eta, an enzyme helping cells replicate despite sun damage, is structured differently in people with XPV. This finding sets the stage for research into therapies to protect XPV patients from skin cancers.
A new study published in The Lancet found that exposure to arsenic in drinking water is linked to increased mortality rates, particularly among those with heart disease and other chronic conditions. Researchers tracked 12,000 people in Bangladesh over a decade to gather data on the health effects of arsenic exposure.
A new study of 1,960 White-Americans and 368 Black-Americans with VTE found that Blacks had a significantly higher proportion with pulmonary embolism and idiopathic PE, as well as a higher incidence of VTE. The study suggests that true causes for these racial differences remain unknown and warrant further investigation.
Researchers at the University of Alabama at Birmingham found that ear tubes can be safely installed in children with cochlear implants to help clear up infections. The study showed no adverse impact on child health and hearing outcomes, allowing for proper management of ear tubes before cochlear implantation.
The USDA Forest Service's More Kids in the Woods program provides week-long summer day camps focused on natural resources themes. The camps, supported by local partners, promote environmental awareness and stewardship among young people.
A new study from the Institute for Aging Research found that nearly 52% of participants who reported a fall were barefoot or wearing slippers at the time. The study recommends wearing well-fitting shoes with slip-resistant soles to minimize the risk of falls among elderly people.
Researchers found that nanoparticles of zinc oxide are twice as toxic to colon cells as conventional zinc oxide. The study's results suggest that accidental ingestion of sunscreen products could lead to toxicity in humans.
Researchers found that patients treated with early combination disease-modifying antirheumatic drug therapy had less radiographic damage in small joints, even after 11 years. Early and aggressive treatment achieves excellent results for most patients, especially those who achieve strict remission at 1 year.
Researchers analyzed bed bug saliva proteins to understand their role in feeding and potential medical applications. The study found unique enzymes that characterize the saliva profile of Cimex lectularius, a blood-feeding insect with over 250 million-year survival success.
Researchers propose a testable model of human tinnitus suggesting that the brain's limbic system, which normally blocks sound sensations sent from non-real sources, is compromised in people with tinnitus. This could lead to new therapeutic approaches by restoring the feedback loop and eliminating phantom sounds.
A mutation in the big-conductance potassium ion channel (BK channel) is linked to epilepsy, altering its dynamics and increasing nerve-cell excitability. The mutation makes part of the channel more rigid, allowing it to toggle open more easily.
The US ranked last in five areas of health system performance: quality, efficiency, access, equity, and healthy lives. Affordable Care Act provisions may improve access and equity, but the country still lags behind others on measures of quality and value.
Research by Paul L. Dunham and his team at Missouri State University found that REM sleep deprivation increases expression of proteins p38, PKA, and P2X3, known for initiating and sustaining chronic pain in migraines.
A study demonstrates that Pycnogenol, a natural plant extract from pine bark, substantially improves symptoms of hay fever. By reducing pollen-specific antibodies and inflammation, Pycnogenol effectively relieves eye and nasal symptoms in patients with allergic rhinitis.
Researchers have developed an animal model that demonstrates the initial stages of atherosclerosis can be predicted by disturbed blood flow. The study identifies genes turned on or off in response to disrupted flow, providing new insights into how exercise may protect against the disease.
The ACGME task force proposes revised duty hour and supervision standards to better match residents' levels of experience and emerging competencies. The new standards aim to improve resident training and patient care by reducing fatigue and minimizing medical errors.
Hurricane Celia strengthened to a Category Two hurricane with maximum sustained winds of up to 100 mph, and NASA satellites confirmed the emergence of an eye.
A new study reveals that thousands of noncoding RNAs have a regulatory role independent of their protein-coding function, communicating with each other to influence cellular microRNAs. This discovery introduces 'competitive endogenous RNAs' and doubles the size of the functional genome, offering new insights into cancer and human disease.
Tropical Storm Darby formed rapidly in the Eastern Pacific Ocean, with NASA's Aqua satellite capturing strong convection indicating speedy strengthening. The storm is expected to strengthen further and make landfall in Mexico within the next 48 hours, prompting residents to monitor its track.
Empa researchers create simple networks of organic nanowires with perfectly monocrystalline structure. The nanowires can be combined to form complex electronic circuits, including solar cells and transistors.
New results from a galaxy survey set the smallest upper limit on the size of the elusive neutrino particle to date at 0.28 electron volts. The research uses a large 3D map of galaxies and cosmic microwave background radiation, providing insights into dark matter.
Researchers used quantum simulations to study hydrogen's behavior under extreme pressure, discovering a discontinuous transition between molecular and atomic states. The critical point occurs at high temperatures and pressures, near 3100°F and 1 million atmospheres.
CIMIT has awarded over $3 million in seed grants to support innovative medical research projects targeting brain injuries, pain management and improving care for wounded warriors. The selected projects aim to accelerate medical innovation and improve patient care through novel approaches and clinical systems.
Researchers have successfully controlled quantum superposition in silicon, a crucial step towards building affordable quantum computers. The breakthrough could enable faster processing of complex information and secure code-cracking capabilities.
African-American women have more advanced breast cancer at diagnosis and poorer survival outcomes compared to non-Hispanic whites. Despite similar surgical care and adjuvant therapy, African-Americans experience lower overall and breast cancer-specific survival rates due to socio-demographic factors.
Researchers found higher levels of oxidative and nitrosative stress markers, including anti-MDA and anti-HNE antibodies, in SLE patients with greater disease activity. These biomarkers suggest an imbalance between reactive oxygen and nitrogen species production and antioxidant defense mechanisms in SLE.
The International AIDS Society calls on donors to uphold their commitment to universal access to HIV prevention, treatment, and care by 2015. Failure to do so would lead to a surge in infections, illness, and death, undermining the credibility of the G8.
A new study has identified a key role for adrenal glucocorticoids in resetting the internal body clock, a finding that could lead to new treatments for jet lag. The research also highlights the importance of timing and location in regulating circadian rhythms.
Researchers have found that modulating the adrenal gland's production of glucocorticoid hormones can regulate the resetting of the internal body clock, providing a new potential therapy for jet lag. This discovery also has implications for those who suffer from rotating shift work and its associated health problems.
A new study has shown that a vaccine-derived strain of poliovirus can be as easily transmitted and likely to cause severe disease as wild-type poliovirus. Vaccination with trivalent OPV is highly effective in preventing paralysis by this serotype 2 cVDPV, making it crucial for efforts to eradicate polio continue.
Researchers from the University of Texas Medical Branch at Galveston have successfully grown new lung tissue using embryonic stem cells and decellularized rat lungs. The breakthrough, published in Tissue Engineering Part A, paves the way for potential applications in treating severe lung disorders such as cystic fibrosis.
A new mouse model has revealed that a diet high in fructose and trans fats can lead to fatty liver disease with scar tissue. The study also identified potential biomarkers for early detection and suggests therapeutic interventions may reverse or protect against progressive liver damage.
A recent study found that 20.4% of peer-reviewed articles published in 2008 were freely available online, with the highest share in Earth Sciences (33%) and the lowest in Chemistry (13%). The study suggests that author-posted manuscript copies dominate certain fields, while OA journals are more common in Medicine and Biochemistry.
A WSU study found that mothers of autistic children experience increased stress due to work demands and lack of flexibility. Nearly 60% have suffered financial problems in the past year, highlighting the need for workplace adaptations to support affected parents.
A team of Vanderbilt chemists has developed a novel method for synthesizing peptides that incorporates non-natural amino acids. The technique streamlines the process, making it easier to create diverse peptides and proteins, which have highly specific biological activity associated with low toxicity.