Researchers found rare variants in the SIAE gene that occur almost nine times more frequently in individuals with autoimmune disorders. These variants interfere with the enzyme's activity or secretion, potentially leading to an increased risk of conditions like rheumatoid arthritis and type 1 diabetes.
Researchers found tooth marks on bones from large dinosaurs and a small marsupial, dated around 75 million years ago. The marks were likely made by ancient mammals, such as multituberculates, which gnawed on the bones for minerals.
Researchers found that monocyte-derived cells can induce myocardial protection by reducing cardiac cell apoptosis and enhancing endothelial cell proliferation. The cells also secrete growth factors with anti-inflammatory properties, which help protect heart tissues from programmed cell death.
The formation of aerosols in the atmosphere is a major source of uncertainty in climate predictions. Researchers are working to understand how aerosols form, particularly at the molecular level. The interaction between organic acids and sulfuric acid can facilitate aerosol formation by creating a critical nucleus.
A new study found that free-range eggs in Taiwan contain at least five times higher levels of certain pollutants than regular eggs. The findings raise concern about the safety of eating free-range chicken eggs due to potential exposure to environmental pollutants like PCDDs and PCDFs.
Researchers at National Jewish Health and the University of Colorado Anschutz Medical Campus have identified a precise protein fragment that can trigger diabetes in mice. The finding contradicts conventional wisdom and suggests that poorly presented peptides may cause autoimmune diseases, including type 1 diabetes.
Researchers have achieved unprecedented spatial and temporal resolution in single-shot images of nanoparticulate catalysts, enabling time-resolved imaging of particles as small as 30 nanometers. This breakthrough could greatly improve catalyst efficiency in various processes crucial to energy security.
A University of Illinois study found that relying too much on e-mail and videoconferences can lead to a lack of trust among team members, which is critical for successful collaboration. The research suggests that businesses should balance the use of technology with face-to-face meetings to recharge relationships and maintain trust.
A Nationwide Children's Hospital study shows that one-third of sickle cell disease patients receiving narcotics were not prescribed laxatives, highlighting the need for increased attention to constipation prophylaxis. The study found that older children and patients with medical admissions were more likely to receive laxatives.
Researchers found gabapentin to be effective in reducing ocular symptoms and improving quality of life for four patients with these conditions. Treatment was well-tolerated, with no adverse effects reported.
Researchers at Tel Aviv University have discovered a way to control the curvature of Airy beams, which can be used to sort molecules according to size or quality. This technology has immediate applications in the pharmaceutical and chemical industries.
Associate Professor Huiming Bao has published research in Nature about massive volcanic eruptions and their atmospheric consequences. The study used computer models and geological data to simulate the sulfur gas oxidation chemistry and atmospheric conditions of North America long before human activities impacted air quality.
The European Research Council has awarded a €3 million grant to study corals and global warming. The five-year CoralWarm project aims to create a mathematical model predicting coral reef changes due to temperature and acidity increases.
Researchers at Georgetown University Medical Center found that no new medical strategies exist to prevent or treat fetal alcohol syndrome, a disorder caused by alcohol exposure during pregnancy. Despite ongoing research, sensitive diagnostic tools are lacking, and more investigation is needed into biomarkers and prevention programs.
Navrotsky's research reveals that particle size significantly affects the energy needed for oxidized reactions, with implications for applications such as hydrogen production and battery efficiency. The study sheds light on how nanoparticles react under different temperatures and conditions.
University of Utah chemists confirm the coexistence of ice and liquid water after crystallization at very low temperatures. They found that rapid ice crystallization makes it difficult to follow the process, but computer simulations revealed a critical temperature zone that may be important for understanding cloud formations.
Researchers used a computer model to show how HCFCs break down into oxalic acid, contributing to acid rain. The study highlights concerns over the environmental impact of replacing ozone-depleting substances with more potent greenhouse gases.
Four Tufts graduate students have won $10,000 from the Dow Sustainability Innovation Student Challenge for their research into sustainable solutions to global challenges. The winners proposed innovative projects on topics such as clean water access, food security, and animal species decline.
A team from Dalian Polytechnic University and City University of Hong Kong developed an experimental glass with heavy metals, which amplifies light signals at a wavelength of 1185 nanometers. The results indicate the potential for this material in both fiber optic networks and lasers.
This issue of Geosphere highlights the geological processes that produce magma pulses and sheets in tabular intrusions. The study reveals a link between shallow igneous intrusions and volcanic activity, demonstrating how intrusive sheeting can destabilize volcano flanks and trigger eruptions.
Researchers found that compstatin, a drug that targets the complement system, can reduce blood clotting during dialysis for end-stage kidney disease. In severe sepsis, compstatin also blocks the activation of both complement and coagulation systems, potentially preventing multiple organ failure and death.
A 110-foot long, 200-ton concrete bridge model at the University of Nevada, Reno withstood a powerful earthquake simulation three times more intense than the 1994 Northridge quake. The design and components passed the test with 10 inches of deflection in support columns, remaining standing.
A study identified nine key symptoms associated with late-onset hypogonadism, including decreased sexual function and energy levels. The researchers found that testosterone treatment may only be useful in a small number of cases, highlighting the need for clear diagnosis criteria.
New research reveals that plate history plays a crucial role in determining volcanic activity, contrary to previous assumptions about mantle temperature. The study found that some regions experienced more volcanic activity than others despite similar geological conditions.
Researchers from the University of Maryland have discovered that crayfish make surprisingly complex decisions by weighing risks against rewards. By studying the animals' neural activity, they hope to gain insights into human decision-making processes.
A recent study has found that women who use IUDs are less likely to become pregnant compared to those using hormone injections. The IUDs' longer duration and lack of hormonal effects also make them a preferred long-term option.
A City College of New York study, supported by $260,415, aims to pinpoint the top 20 sites for hydrokinetic energy in New Jersey. The research, led by Dr. Hansong Tang and Roger Bason, will use computer modeling and field measurements to estimate tidal energy potential.
A major JAMA study found that patients with cystic fibrosis who tested positive for MRSA had a significantly higher risk of death compared to those without the infection. The study, which tracked over 19,000 CF patients, showed an approximate 1.3 times greater risk of death among those with detected MRSA.
Researchers found that administering nab-paclitaxel weekly resulted in a 48% response rate and less severe side effects compared to every-three-week dosing. The study showed improved anti-tumor activity and reduced nerve damage with the novel formulation.
Researchers at the ARS Natural Products Utilization Unit have found a way to make sorghum less toxic to certain crops, while increasing its weed-fighting abilities. This discovery may lead to more sustainable agricultural practices and reduced pesticide use in other crops.
Researchers analyzed surgical outcomes of non-small cell lung cancer patients over 30 years, finding improved survival rates with earlier stage diagnoses. The increase in patients diagnosed with early-stage adenocarcinoma is thought to contribute significantly to the favorable results.
Researchers at the University of Cincinnati propose that the structure of vodkas is responsible for variation in taste. The team found that different vodkas have varying levels of a cage-like hydrogen-bonded structure, which could affect the way they are perceived by the palate.
Researchers at Nanjing University have identified a novel biomarker for raw milk quality detection, enabling more accurate monitoring of milk content. The discovery could lead to the development of new milk products tailored to specific groups, offering improved health benefits.
The study reveals that chloride ion accumulation in lysosomes is crucial for protein degradation, rather than just acidification. This finding has significant implications for understanding kidney stone disease and neurodegeneration.
RG7204, a BRAF inhibitor, has shown significant preclinical activity against melanoma by inhibiting proliferation of tumor cell lines and inducing partial or complete tumor regression. The compound also improved survival rates without associated toxicity in preclinical models.
A new UNC study found that African Americans with two or more medical conditions had almost zero surgeries, while white patients in the same situation had surgery just as often. The study also found that lack of a regular source of care led to significantly lower surgical rates for black patients.
A Cochrane Systematic Review suggests that giving patients oxygen during a heart attack may increase the risk of dying. Despite widespread use, there is little evidence that oxygen therapy improves outcomes for heart patients and may even cause further damage.
Research published in PLOS Medicine found that pregnant women with an inherited condition making them more likely to form blood clots only face a small increase in the risk of miscarriage or stillbirth. The study also showed no significant association between thrombophilia and placenta-related problems, suggesting that prescribing anti...
Researchers at Heidelberg University Hospital found a promising new treatment for pancreatic cancer combining sorafenib with sulforaphane, an anti-cancer compound in broccoli. The combination treatment inhibits resistant tumor stem cells and blocks metastasis without causing additional side effects.
A recent study found that naturally occurring protein IL-10 can prevent and reverse brain damage caused by meningitis in newborns. The research suggests that IL-10 acts to clear antibiotic-sensitive and antibiotic-resistant E. coli from the circulation, thereby preventing or restoring damaged brain tissue.
Researchers warn that using a cell phone while driving can lead to relationship problems due to impaired attention and divided focus. This includes misunderstandings, hurt feelings, and conflict, as conversations are affected by delayed reactions and lack of nonverbal cues.
A new procedure, transcatheter valve-in-valve implantation, offers hope for elderly patients with high surgical risk, reducing symptoms and complications. Two deaths occurred in high-risk patients, highlighting the need for adequate patient selection and interdisciplinary care.
A new study by Case Western Reserve University researchers found that leaded gasoline was the predominant source of lead exposure for African-American children in Cleveland during the latter half of the 20th century. The study used dental records and other data to show that lead levels in teeth increased dramatically during this period...
Researchers found similar leukaemia-free survival rates for unrelated cord blood transplants and matched bone marrow or peripheral blood progenitor cell transplants. UCB transplantation was also linked to lower rates of acute and chronic graft-versus-host disease.
The study expands protein analysis to C-terminal proteins and enables assessment of specific regions' roles in biological functions. This new approach can be applied ex-vivo or in-vivo and has implications for understanding essential protein functions.
Researchers at Argonne National Laboratory have developed a new material that can decompose organic molecules in polluted water using visible light. By decorating silver chloride nanowires with gold nanoparticles, they have created a photocatalytic system that can break down pollutants like methylene blue.
Researchers found that voters rely heavily on nonverbal cues, such as facial appearance, to make judgments about politicians' competence. Appearance-based competence judgments reliably predict both voting decisions and election outcomes, particularly among less knowledgeable voters who watch a lot of television.
The collaboration aims to identify genes and novel drug targets related to the onset and progression of Huntington's disease. The team will use induced pluripotent stem cells from patients with HD to screen for drugs that might delay, prevent, or reverse the devastating condition.
Robert H. Wurtz's groundbreaking research on visual information processing and eye movements has led to a deeper understanding of how the brain controls behavior. His discoveries have inspired hundreds of scientists to study cognitive processes, including attention and perception.
A study has found that genetic mutations in three genes may predispose individuals to suicidal behavior. The research identified a model able to differentiate between people with and without a history of suicide attempts using an algorithm based on SNPs from these genes.
Tall fescue toxicosis is a costly disorder affecting forage-livestock agriculture, with no cure but proven management techniques available. The new guidebook covers management strategies such as endophyte testing and supplement feeding to lessen the impact of toxicosis.
The Iowa State researcher's 3D imaging technology has been used by Rock stars like U2 and featured in Radiohead's music video. The technology requires less data and memory than current tools, making it practical for the entertainment industry.
Researchers from the University of Montreal have identified an enzyme called NOX2 that generates highly reactive oxygen derivatives to activate defense genes and molecules against viral invasions. The study reveals how these free radicals serve a critical role in mounting an immune response to viral infections.
Researchers found that 9-month-old babies can recognize 'more than' or 'less than' relations across numbers, sizes, and durations of objects. This suggests that humans may be born with a generalized system of magnitude that helps them make predictions about the world from an early age.
A study by University of South Florida and Johns Hopkins University found that pediatricians should not hesitate to discuss a child's weight with parents. Pediatricians can help identify overweight preschoolers and prevent serious health problems like Type II diabetes and heart disease.
Researchers at the Universities of Liverpool and Leeds found that prior guidance on cross-examination techniques can improve witnesses' ability to respond accurately. Participants who received guidance were better equipped to handle complex questions and less likely to make errors.
Researchers found that the 2009 H1N1 influenza vaccine may also protect against the lethal 1918 Spanish influenza virus, alleviating bioterrorism concerns. The study demonstrates cross-protection, showing that people vaccinated against H1N1 may also be protected against 1918.
Identification of IKKβ as a crucial signaling molecule in melanoma development may lead to new targeted therapies. The study suggests that treating patients with specific genetic profiles could enhance treatment efficacy.
Physicians play a stronger role in asthma patient adherence by monitoring medication use and reviewing electronic prescription information. However, few doctors access detailed adherence data, highlighting the need for effective ways to encourage patients to stay with their prescription regimens.
The University of Illinois at Chicago has received a $3 million grant to expand its patient safety process to six additional hospitals. The process, known as the Seven Pillars, aims to improve communication, learn from mistakes, and ensure timely resolution when patients are harmed.