A new microRNA screening assay detected the majority of early-stage colorectal cancers with good specificity and sensitivity from a single plasma sample. The test has the potential to be safe, cheap, robust, accurate, and convenient for national screening programs.
Researchers identified duplicated or missing DNA segments in children with ADHD, suggesting a neurodevelopmental disorder. The study also found overlap between ADHD and autism, suggesting a shared biological basis.
A study by Intel Labs, Penn State, and Duke University found that 15 apps send users' geographic location to remote servers. Additionally, 20 applications shared unique phone identifiers and phone numbers with developers without user consent.
Researchers at McLean Hospital have been awarded a $1.9 million grant to continue their research into creating human induced pluripotent (iPS) stem cells using a method that eliminates cancer risks. The goal is to develop universal red blood cells and platelets for transfusion, eliminating immune rejection problems.
Mount Sinai School of Medicine is leading a $16.5 million grant program to develop nanotechnology tools for diagnosing and treating cardiovascular disease. The center aims to utilize nanotechnology to better prevent and treat atherosclerosis, heart attack, and heart failure.
Researchers at WUSTL will explore therapies and diagnostic tools for heart and lung diseases using nanotechnology. The project aims to improve treatment options for cystic fibrosis, acute lung inflammation, and atherosclerosis.
The Penn Medicine Parkinson's Disease and Movement Disorders Center is one of 18 official study sites for the PPMI, a $40 million, 5-year observational clinical study that aims to identify biomarkers of Parkinson's disease progression. The study will use advanced imaging, biologics sampling, and behavioral assessments to provide valuab...
A global study reveals that multiple environmental stressors threaten the world's rivers, affecting human water security and biodiversity. The research team integrated maps of 23 stressors to provide a single index, highlighting areas with high incident threat levels.
A study by Rice University found that investment analysts' negative stock recommendations increase the probability of CEO dismissal. The researchers analyzed panel data on S&P 500 companies from 2000 to 2005 and found a significant impact of downgrades on CEO turnover decisions.
A new computer simulation by Gurtina Besla and her colleagues shows that the Magellanic Stream resulted from a past close encounter between the Large and Small Magellanic Clouds, rather than the Milky Way's gravity. The study challenges traditional models of galaxy formation.
Researchers at UIC's Brodie Laboratory have successfully developed a technique to reattach teeth using stem cells, which could lead to a major advance in the battle against gum disease. The new strategy involves using periodontal ligament stem cells to form new fibrous attachments between the tooth and bone.
Researchers at Nationwide Children's Hospital and two other centers will explore new treatment strategies for Duchenne muscular dystrophy, a debilitating disease affecting children and young adults. The goal is to identify existing drugs that can inhibit muscle fibrosis and develop non-invasive imaging techniques to assess muscle damage.
Researchers developed two non-invasive testing methods to identify dissolved cocaine in wine or rum bottles using Raman spectroscopy and magnetic resonance spectroscopy. These techniques allow customs officials to quickly detect cocaine without opening the bottle, potentially tracking the recipient without arousing suspicion.
Researchers at Children's Hospital Los Angeles have discovered a way to overcome radiation resistance in leukemia cells by targeting the SYK tyrosine kinase molecular target. This breakthrough could improve treatment outcomes for children with relapsed leukemia, who currently face poor survival rates.
A new study from the University of Toronto suggests that having more schedule control at work can lead to blurring of boundaries between work and family life. Researchers found that individuals with partial or full schedule control experienced less negative consequences in terms of work-family multitasking activities.
A study found that having an incarcerated father is associated with substantially elevated risks of marijuana and other illegal drug use in adolescence and early adulthood. Young people with incarcerated fathers also exhibited elevated trajectories of marijuana usage, extending into their mid-twenties.
A recent study found that less than half of essential workers are willing and able to report to work during a serious pandemic. Motivation to work is tied to workplace safety measures, trust in employers, and past experience. Employers can increase worker willingness by providing resources and support for personal obligations.
A new report warns that national targets in the Copenhagen Accord may not be enough to limit global warming to 2°C, threatening a 4.2°C rise in temperature and the destruction of coral reefs by 2100.
A global team of scientists, led by Albert Einstein College of Medicine researcher Robert Kaplan, has identified hundreds of gene variants that influence adult height. The study, which analyzed data from nearly 184,000 people worldwide, proves the effectiveness of genome-wide association studies in explaining observable traits.
Research indicates that children experiencing multiple family living arrangements during childhood may face negative effects on their well-being. Family instability can impact a child's physical and emotional health in the short- and long-term, according to Susan L. Brown's new study published in the Journal of Marriage and Family.
A new drug, tanezumab, significantly reduces knee pain in osteoarthritis, but a small number of participants developed worsening arthritis and bone changes requiring joint replacements. The FDA is examining data to decide on the drug's future use.
A University of Michigan study found that people who lie on the phone feel a stronger desire for mouthwash, while those who lie via email want hand sanitizer. This suggests a connection between abstract moral issues and concrete physical experiences.
A large international study has identified hundreds of genes contributing to human height, revealing that a combination of multiple genes determines an individual's stature. The research points the way for future studies exploring how these genes interact to impact growth and development.
A study by the University of Melbourne found that close relatives of women diagnosed with breast cancer before age 35 have a higher risk of developing other cancers. These include prostate, lung, brain, and urinary tract cancers, with increased risks ranging from 2 to 8 times higher than expected.
Researchers at Florida State University developed a novel genetic screening method to identify drug-resistant HCV strains and molecular-level mechanisms. This technology also works on HIV and influenza, offering a potentially life-saving solution for over 170 million people worldwide infected with HCV.
A UTHealth researcher has been awarded a three-year grant to develop an early biochemical diagnosis for Alzheimer's disease. The goal is to detect the disease years before symptoms appear, allowing for treatment to begin earlier and potentially preventing death.
The new research program aims to address pressing concerns in the plant sciences, including food production and human health. It will provide critical support to up to 15 plant scientists over five years, selecting those with exceptional talent and innovative ideas.
A study of 58 caregivers found that a lack of understanding and help from friends and relatives is the biggest cause of stress. Caregivers reported signs of anxiety and depression due to common problems such as criticism, social isolation, and difficulty sustaining themselves and their families.
Researchers discussed novel approaches in cleft lip repair and highlighted advancements in cochlear implant technology. A new study also explored the importance of health literacy, cultural competency, and health disparities for patients with diverse backgrounds.
A recent analysis by UT Southwestern Medical Center found that more people are consuming alcohol now than in the early 1990s. The study, which gathered data from over 85,000 respondents, suggests that a range of factors, including social, economic and ethnic influences, contribute to the increase.
The ISIM structure passed extreme cryogenic temperature tests without cracking, with thermal contraction and distortion measured to be within the design requirement. The unique composite laminate and bonding technique used in its construction were successfully tested, ensuring the telescope's instruments remain in precise locations.
A new study has found prenatal cardiac defects in mice with Spinal Muscular Atrophy (SMA), a leading genetic cause of infantile death. The discovery has significant implications for treatment, suggesting that the disease may be multisystemic and requiring therapies beyond just motor neurons.
A new study finds that social rejection triggers a momentary decrease in heart rate, mirroring the brain's response to physical pain. Participants' heart rates slowed in anticipation of and after receiving news about another person's opinion of them, with further drops observed when told they were rejected.
Researchers found that circulating tumor cells (CTCs) can provide real-time information on patient's current disease state through biomarker assessments. The technology has potential for non-invasive detection and analysis of cancer biomarkers.
Researchers have developed a model that simulates how disasters affect critical infrastructure, including bridges, roads, water treatment services, and vital economic components. The model aims to identify vulnerable elements to take proactive measures or find alternatives.
Scientists have created a substance that targets amyloid structures in semen and weakens HIV's ability to infect the body's immune cells. The experimental compound makes it harder for HIV particles to stick to human immune cells, offering a new lead in developing a microbicide to prevent HIV transmission.
Scientists at the University of Leicester are pioneering the use of turmeric extract to target chemo-resistant cancer cells. The research aims to improve chemotherapy effectiveness and prevent disease recurrence.
A study published in the Journal of Evolutionary Biology found that physical attractiveness is linked to evolutionary, social, and economic success. Young, tall, and long-armed women were rated as the most attractive, with narrow waists and a low BMI also contributing to their appeal.
Research published in Annals of Oncology suggests that intrauterine devices releasing progestin hormone levonorgestrel combined with GnRH injections can halt and reverse cancer growth in women aged 40 or younger. The treatment has shown promise in treating specific types of endometrial cancer, preserving fertility for young women.
Researcher Adeela Arshad-Ayaz argues that multicultural education has failed to promote cross-cultural understanding due to inadequate teacher training. She proposes an alternative approach integrating discussion of global politics and social class to create a more equitable society.
A new study by University of Notre Dame ecologist Jennifer Tank and colleagues found that streams throughout the Midwest receive transgenic materials from corn crop byproducts six months after harvest. The research detected Cry1Ab insecticidal protein in 13% of stream sites and dissolved in 23% of water samples.
A genetic inversion in the monkeyflower plant's genome contributes to its adaptation to different environments, leading to reproductive isolation and a shift towards becoming two separate species.
The Goddard team designed a one-of-a-kind structure made of never-before-manufactured composite material that withstood extreme cold temperatures. The structure survived temperatures as low as 27 Kelvin (-411 degrees Fahrenheit), exceeding design requirements.
A meta-analysis of 70 randomized trials found that disease-modifying antirheumatic drugs (DMARDs) and glucocorticoids significantly reduced radiographic joint destruction, similar to biologic agents. Combination therapies also showed promise in reducing structural damage.
A University of Michigan study shows that constructive conflict resolution strategies can lower divorce rates, while destructive behaviors and withdrawal are associated with higher separation rates. Researchers found racial differences in conflict behavior patterns, with Black couples more likely to withdraw during conflicts.
Researchers have developed a new method to analyze neutron reflection to identify buckyballs within polymer-based photovoltaic cells. This breakthrough technique allows for more efficient and cost-effective production of solar cells, which could lead to widespread adoption.
Biologists at Tufts University have discovered that sodium plays a key role in initiating a regenerative response after severe injury, enabling the regeneration of injured spinal cord and muscle. A specific drug-based treatment triggers an influx of sodium ions into injured cells, breaking new ground in biomedicine.
Researchers found that African-American patients with non-small cell lung cancer have similar rates of EGFR mutations, making targeted therapies like erlotinib a viable option. This discovery challenges previous assumptions about racial disparities in lung cancer treatment.
A 59-year-old patient's vertigo and severe hearing loss were alleviated with surgery, restoring her hearing in an extremely rare occurrence. The case highlights the risks of using cotton swabs to clean ears without medical guidance.
Three USU doctoral students receive fellowships to study schistosomiasis, multiple sclerosis and tuberous sclerosis complex. The HJF program aims to develop new drug targets and treatments for these diseases.
Case Western Reserve University researchers develop e-SMART-MH technology to improve patient-provider communications and manage mental health. The project aims to empower young adults to take control of their mental well-being, overcoming stigma and ensuring timely treatment.
Researchers at Monell Center discovered a genetic variation linked to impaired olfactory perception, affecting approximately 14% of individuals. The study used DNA analysis and sensory testing to reveal the connection between an olfactory receptor gene and sulfurous compound sensitivity.
Researchers at Tel Aviv University found dew essential for plant growth in semi-arid zones like the Eastern Mediterranean. Dew provides moisture to plant leaves, enabling photosynthesis and growth during early morning hours.
Experts speculate on future of H1N1 pandemic virus, predicting low mortality rates due to existing immunity in the population. The degree of immunity and potential changes to the virus will impact the upcoming influenza season.
Researchers Prof. Dr. Albert Newen and Christoph Michel propose that self-deception can be a motivating factor in certain situations, while maintaining basic rational evaluation processes intact. However, excessive self-deception can lead to reality distortion and harm.
A new study found that HIV-infected individuals who start antiretroviral therapy (ART) soon after acquiring the virus have stronger immune responses to other pathogens compared to those who start ART later. Early treatment restores resting memory B cells and reduces immature B cells, leading to improved immune system function.
Teens with certain psychiatric diagnoses, such as bipolar disorder and externalizing disorders, are more likely to engage in high-risk sexual behaviors. The study found that those with mania are at an even higher risk for HIV and STIs, having significantly more sexual partners and being four times as likely to have an STI.
A new disposable device based on microfluidics can efficiently capture cancer cells overexpressing HER2, enabling therapy with trastuzumab. The device offers a non-invasive alternative to current methodologies and has shown promising results in early studies.
A section of northwestern Harris County is sinking rapidly due to groundwater withdrawal and subsidence. Researchers analyzed GPS data over a decade, finding that some areas sink up to 5.5 cm/year.
New research from the University of Southern California found that sparkling drinks activate pain sensors in the nasal cavity, similar to mustard and horseradish. The study discovered a specific type of cell responsible for this sensation, known as TRPA1.