A consortium of cancer researchers has identified four chromosome locations with genetic changes that may alter a woman's risk of developing ovarian cancer. These findings are based on a large genome-wide association study and could lead to individualized risk assessments for ovarian cancer.
Researchers at the NHLBI found that adding tiotropium bromide to low-dose inhaled corticosteroids is more effective than doubling corticosteroids alone and as effective as adding a long-acting beta agonist. The treatment showed significant improvements in asthma control, including increased symptom-free days.
Researchers at Newcastle University create a wireless sensor that can withstand extreme temperatures to monitor volcanic activity and collect real-time data. The device uses Silicon Carbide electronics, which also offers radiation tolerance for potential use in the nuclear industry.
A new material can mark early-stage tumors using ultrasound imaging, potentially reducing the need for second surgeries and making operations more comfortable for patients. The durable material is made of porous glass spheres filled with a gas that helps it last longer.
Two studies found new genetic variants linked to ovarian cancer risk in the general population, particularly in women with serous ovarian cancer. The variants were more common in women with aggressive disease and may be used for closer surveillance and preventive approaches.
Researchers have discovered a new type of nanoparticle shaped like the Star of David, which may lead to new ways for sensing glucose in diagnosing diabetes. The nano-cages also showed promise as sensors for hydrogen peroxide detection, boosting electrical signals by 200 fold.
Researchers identified five genetic variants associated with increased breast cancer risk in BRCA1 carriers, including those related to estrogen-receptor-negative and triple-negative disease. These findings may help identify individuals at lower or higher risk of cancer, enabling tailored cancer prevention strategies.
HIV-1 virus uses ATP to remove AZT, a widely used AIDS treatment, allowing it to replicate itself. This discovery helps researchers understand why anti-AIDS treatments can fail, enabling the development of more effective treatments for HIV patients.
Scientists have found a key protein regulating biological clocks also regulates glucose production in the liver, improving diabetic mice health. Altering this protein can open new treatments for obesity and type 2 diabetes.
A research team from Rochester Institute of Technology conducted a life-cycle assessment of organic solar cells, revealing lower embodied energy compared to conventional inorganic devices. The study also found potential benefits for manufacturing, including low-cost solution processing.
Typhoon Fanapi is approaching Taiwan with strong convection and a tight circulation center, reaching speeds of 97 mph. NASA's Aqua satellite data shows the typhoon consolidating, with a 11-mile-wide eye and a small gap in the eyewall.
Researchers confirm partial melting of mantle at 2900 km depth, revealing a deep magma ocean. The study uses X-ray diffraction to characterize the passage from solid to liquid state, shedding light on the dynamics and composition of the Earth's depths.
The US Department of Energy has awarded a $1.05 million grant to the University of California - San Diego and San Diego State University to develop and execute commercialization plans for promising renewable energy technologies. The program aims to enhance university-based innovation ecosystems in the region.
Marshall University researchers Dr. Elaine Hardman and Dr. Philippe Georgel have received over $1 million in federal funding to study the effects of omega-3 fatty acids on breast cancer development, particularly in female offspring. They aim to identify genetic changes associated with a maternal diet rich in omega-3 fatty acids and dev...
Sam Houston State University will study the use and effectiveness of the national Ballistic Information Network (NIBIN) database to connect crimes to a single firearm. The research aims to identify best practices for improving the system's effectiveness and understand why some law enforcement agencies do not use it.
Research at the University of Liverpool has led to a potential breakthrough in detecting liver damage, using paracetamol as a basis for study. The team discovered specific proteins in the blood indicate early liver cell damage and can assess the extent of damage more accurately.
Agricultural Research Service microbiologist Ilenys Pérez-Díaz and her colleagues discovered that certain Lactobacilli species can modify azo dyes into non-mutagenic substances. This finding has potential applications for wastewater treatment, making food-grade bacteria a promising option for cleaning up textile industry dye waste.
Researchers at Emory University School of Medicine have found that deleting a certain gene in mice can improve their learning and memory abilities. The RGS14 gene, which is primarily active in one region of the hippocampus, appears to limit some forms of learning and memory when present.
A recent study found that violent video games can stimulate aggression for an extended period of time, with effects lasting up to 24 hours. The researchers also discovered that women who played violent games did not experience increased aggression in the long term.
Hurricane Karl's powerful thunderstorms featured very high icy cloud tops, while moderate to heavy rainfall was observed from the storm. The GRIP mission gathered valuable data on Karl's rapid intensification, which went from a tropical storm to a Category 3 hurricane overnight into Friday.
The University of Southampton is leading a £600,000 project to study and revive medieval conductus music. Researchers will examine centuries-old manuscripts and create sound recordings of the genre, making it accessible to modern audiences.
A phase 2 trial found that pazopanib, an antiangiogenetic drug, significantly improved outcomes for patients with advanced differentiated thyroid cancers. Approximately 49% of patients experienced a partial response, with two-thirds likely to have a lasting response over 1 year.
Researchers found that traditional programs may not be effective for all teens, but targeted approaches may help curb aggression. Factors such as poverty, academic troubles, and depression can increase the risk of fighting among certain groups.
Researchers have found a possible new target for fighting cystic fibrosis, exploiting the crosstalk between two chloride ion channels in mucous gland cells. The study suggests that activating one channel could compensate for the lack of CFTR functionality in affected cells.
Researchers aim to create a sustainable water treatment process using moringa seed, which can kill bacteria and remove sediment from water. The system's success depends on optimizing the amount of moringa seed needed to achieve effective water purification without compromising its shelf life.
Permanent night lighting affects songbirds' reproductive behavior, with males singing earlier and females laying eggs up to 1.5 days sooner in artificial light environments. This can lead to maladaptive mate-choice decisions, potentially impacting survival and fitness.
Researchers have found that rod cells in the retina play a crucial role in setting internal biological clocks, even in low light conditions. This discovery has important implications for understanding circadian rhythms and sleep disorders, particularly in older adults who may lose their rod cells to age.
A study published in Preventive Medicine found that teenagers spend significantly more time watching TV and engaging in sedentary behavior on weekends. The researchers analyzed data from over 3,000 European adolescents and found that having a computer in the bedroom reduces the risk of excessive TV watching.
NASA's Aqua satellite captured visible image of Hurricane Julia, weakened by Hurricane Igor's outflow, breaking a record for the most intense hurricane east of the Azores. The storm is expected to move west-northwest then turn northeast, staying at sea.
A study published in PLoS One suggests that minocycline plus N-acetylcysteine may be a valuable treatment for traumatic brain injury. Researchers at SUNY Downstate Medical Center found a synergistic improvement of cognition and memory after experimental traumatic brain injury, and are planning to bring this combination to clinical trials.
Researchers at Mayo Clinic found that pazopanib significantly decreased progression rate in patients with metastatic, rapidly progressive differentiated thyroid cancers. The median progression-free survival time was 11.7 months, with an overall survival rate of 81 percent at one year.
A mathematical analysis suggests that isolating terrorist network hubs is more effective than targeting the entire network. The study uses complex systems tools to analyze and model terrorist networks, finding that soft targets are not worth pursuing. Instead, focusing on the key hubs can lead to successful defeat.
Scientists at Huntsman Cancer Institute link loss of Apc to DNA demethylase, a system that erases DNA methylation. This system stalls normal intestinal cell development, leading to stem cell-like cells. Inhibition of the demethylase restores normal development and provides new opportunities for colon cancer treatment.
A new study found that girls without a biological father are more likely to enter puberty at an earlier age, especially in higher-income households. The study suggests that familial and contextual factors play an important role in the onset of puberty.
The childhood obesity epidemic among children and teenagers in the US is growing at an alarming rate, tripling over the past 30 years. Effective weight management requires a multidisciplinary approach drawing from medical evidence, best practices, and innovative initiatives.
A computer model found a network of genes that can trigger TB's dormant state, switching it from fast-growing to slow-growing. The study reveals potential for a persistence switch that could explain why TB is so widespread and deadly.
A new report by World Vision highlights the need for direct healthcare investment in families and communities to tackle preventable child and maternal deaths. The organization calls on world leaders to prioritize these efforts to meet Millennium Development Goals (MDGs) 4 and 5 targets.
Researchers reveal the structure of CENP-A, a molecule that plays a central role in DNA duplication and equal distribution into two daughter cells. The study provides insights into how CENP-A marks centromere location on each chromosome.
The Clean Energy Trust has received a $1 million grant to transfer research into clean-energy technologies and businesses. The trust will provide seed money, business training, awareness education, and sector-specific support to Illinois universities and science labs.
Researchers will investigate how climate change affects Great Lakes water quality, focusing on extreme weather events and their impact on nutrient, pesticide, and sediment levels. The study aims to develop strategies for watershed councils and government entities to reduce water quality impacts.
The study aims to find a difference in how a susceptible person responds to hydrocodone compared to a nonsusceptible one. The researchers hope to discover an indicator of susceptibility to dependence on painkillers like hydrocodone.
Researchers developed a special sequence of high-precision electromagnetic pulses to protect the arbitrary quantum state of a single spin. This breakthrough enables the use of nitrogen-vacancy centers in diamond as highly sensitive nanoscale magnetic sensors and potentially, qubits for larger-scale quantum information processing.
A new study found that the Alzheimer's drug donepezil enhances perceptual learning in healthy adults, particularly in tasks involving motion direction discrimination. The researchers tested 12 healthy adults and showed a significant improvement in performance after training under the influence of donepezil compared to a placebo.
Hurricane Julia has weakened to a Category 2 storm due to wind shear and cooler sea surface temperatures. The storm is being pulled northwest by mid-level winds, causing its main convection to shift away from the center, resulting in weakening.
The amount of development aid to maternal, newborn, and child health (MNCH) doubled between 2003 and 2008, but its proportion relative to overall aid remained unchanged. The largest increases were made by the US, UK, EU, GAVI, and Global Fund, while others saw stagnation or fluctuations.
Research team isolates aerosol particles in near-pristine pre-industrial conditions, shedding light on cloud formation and precipitation. Organic compounds from plants are found to be a primary source of submicron particles, which can affect climate.
A new study found that taking a placebo improved symptoms in about one-third of women with low sexual arousal, with the most improvement occurring during the first four weeks. The key predictor of symptom change was an increase in satisfying sexual encounters, suggesting a need to investigate behavioral factors more closely.
A new University of Michigan study documents the impact of war on Palestinian and Israeli children's mental health. The research found that nearly half of Palestinian children between 11-14 reported witnessing violence, leading to significant increases in post-traumatic stress symptoms and aggressive behavior.
Scientists have used a new seismic method to investigate the collision process between India and Tibet, revealing a more pronounced boundary between rigid lithosphere and softer asthenosphere. The study provides insights into the processes involved in the collision and aims to reduce earthquake risk in the region.
A special issue of DNA and Cell Biology features undergraduate research projects that demonstrate the valuable contributions of young scientists. The studies showcase innovative approaches to bioluminescence testing, mutant gene mapping, telomerase regulation, and fruit fly metabolism.
Scientists at the University of Calgary found that available area is the most important factor driving flower diversity, with family traits coming in second. The study suggests that geography and morphology play a significant role in shaping biodiversity patterns.
Researchers created a comprehensive catalog of large craters on the moon to study the chaotic early days of the inner solar system. The analysis suggests that larger projectiles dominated the bombardment, ending around 3.8 billion years ago.
Research shows that artificial night lighting impacts dawn song in forest-breeding songbirds, causing them to sing earlier and females to lay eggs a day and half earlier. This can lead to lower-quality offspring, as females may mate with lesser males.
Simon Cocklin, Ph.D., wins the ProteOn XPR36 Giveaway Program for his novel research applications for surface plasmon resonance technology. He plans to use the system in his lab and make it available to other researchers at Drexel University.
New Caledonian crows use tools to extract wood-boring longhorn beetle larvae from burrows, providing a nutritious food source. The crows' tool use is energy-efficient and profitable, suggesting that unusual foraging opportunities have selected for their sophisticated behavior.
A new study argues that synthetic life sciences require a global regulator to detect pathogenic agents and ensure approved purposes for DNA sequences. However, current technology is insufficient to create an effective clearinghouse, highlighting the need for improved screening software and procedures.
Researchers isolated aerosol particles in near-pristine pre-industrial conditions, providing crucial clues about cloud formation and differences between natural and polluted environments. The finding could help understand global climate change and inform modeling of anthropogenic perturbations.
More than 100 marine scientists advocate for an integrated European network of long-term marine observatories to provide reliable data for sustainable use of seas. The network aims to reduce uncertainty about sea-level rise and its impact on coastal defences, saving millions annually.
Research shows early metabolic abnormalities due to poor diet and exercise may increase risk of asthma in children, regardless of body weight. The study implicates metabolic disorders directly in the development of asthma, suggesting a new way of viewing diet and lifestyle as risk factors.
Oregon State University researchers have successfully loaded biological molecules onto nanosprings, a nanostructure that maximizes surface area in microreactors. The findings may lead to new nanotech applications in pharmaceuticals, biological sensors, and biomedicine.