A new simulation by researchers at the American Museum of Natural History and University of Cambridge shows that regions of outward and inward migration in a protoplanetary disk can safely trap planets on orbits. This helps explain how Earth formed without falling into the Sun.
Researchers at the University of Alberta have identified a universal mechanism that ensures peroxisomes transfer into cells after division, potentially leading to prevention or treatment of deadly disorders. The discovery has implications for screening carriers and could help babies born with peroxisome disorders survive longer.
The study reveals that wild Iberian horses played a role in the origin of modern Iberian domestic stock, with their maternal lineages present in ancient DNA sequences. The researchers also found evidence of a completely independent domestication episode or restocking process using Iberian maternal lineages.
University of Florida urologists have developed a robot-assisted vasectomy reversal procedure that cuts average surgery time by 20 minutes, comparable to traditional microscope methods. The robotic procedure also shows quicker return of sperm count and improved efficiency.
A study published in the Journal of Infectious Diseases found that each additional 1.1 pounds of birth weight decreases tuberculosis risk by 46% among identical twins. The association is stronger for males, with an 87% reduced risk, and sheds light on the developmental origins of health and disease.
UC researcher Michal Polak confirms one of Darwin's theories by showing that the spines on Drosophila bipectinata males assist them in copulation. The study found that removing these spines resulted in drastic reductions in ability to copulate and compete for mates.
A study of 1,243 male US veterans with moderate-to-advanced chronic kidney disease found that both high and low blood calcium levels increased the risk of dying prematurely. High calcium levels were linked to a 31% increased risk, while low levels resulted in a 21% higher mortality rate.
A key epigenetic process in the brain's pleasure circuits is altered by chronic cocaine exposure, contributing to an acquired preference for cocaine. By reversing this epigenetic change, researchers were able to block gene expression changes and inhibit cocaine preference.
Researchers at the Institut de recherches cliniques de Montréal have identified a new molecular pathway required for the guidance of retinal axons within the optic chiasm. This guidance relies on the Boc receptor, which could lead to therapies stimulating axonal growth after injury or in neurodegenerative disorders.
Researchers propose integrating NTD interventions into the regular health system, leveraging resources from malaria, HIV/AIDS, and tuberculosis programs. Careful planning and community engagement are crucial for successful integration and co-implementation of these efforts.
Researchers have made a breakthrough in engineering nanoscale materials, enabling the creation of large-scale arrays of individual structures with precise locations. This discovery could lead to advancements in sensing, transistors, and other applications.
A study published in Cancer Cell reveals that epigenetic differences can distinguish patients with acute myeloid leukemia (AML) into subtypes with varying responsiveness to therapy. A set of 15-gene DNA methylation biomarkers was found to be highly predictive of patient survival.
A team of experts found that knowing fish spawning habits and oceanographic models can increase both conservation and fisheries profitability. Spatial information is key to achieving this balance.
Dr. Jay Kolls' research team has identified a unique group of white blood cells that rapidly produce cytokines to increase resistance to pneumonia. The grant will investigate the role of lung epithelium as the primary recipient of these signals and explore how these cells control infection defense in the lung.
Researchers observed a nanoscale guitar string-like behavior in cobalt niobate, with atomic scale vibrations exhibiting the golden ratio. This discovery reflects a hidden symmetry and special property of the quantum system, with potential implications for future technology.
The updated childhood vaccine schedule recommends the H1N1 influenza vaccine for children over 6 months and prioritizes combination vaccines. The revised schedule also includes recommendations for human papillomavirus (HPV) and meningococcal vaccines, aiming to protect against cervical cancer and meningococcal disease.
A Massachusetts General Hospital study found significantly more coronary atherosclerotic plaques and obstructive coronary artery disease in HIV-infected men with minimal cardiac risk factors. The research highlights the importance of addressing cardiovascular risk factors early in HIV disease.
A study in Psychological Science reveals that hand amputation distorts visuospatial perception of the action space. Participants with amputations underestimated distances relative to their intact limbs. The research suggests losing a hand may 'shrink' the action space, leading to permanent spatial perception distortions.
A negative physical education experience during childhood can have a lasting impact on a person's attitude towards physical activity. Research by University of Alberta professor Billy Strean highlights the importance of creating a fun and playful environment for young athletes.
Researchers found that RA patients treated with rituximab in combination with methotrexate had the same immune response to the tetanus vaccine as those treated with methotrexate alone. However, patients on rituximab had a reduced response to the pneumonia vaccine compared to those on methotrexate alone.
A study of critically ill H1N1 children found that serious complications developed quickly and unpredictably, with great variations from patient to patient. The virus behaves variably in different patients, highlighting the need for rapid screening tests and preemptive antiviral medications.
Researchers at Stanford University School of Medicine identified a new method for reducing drug side effects by focusing on neglected areas of cell-surface proteins. By analyzing the shape changes in response to drugs, they discovered potential targets for more selective and effective medications.
Kai W. Wucherpfennig, a Dana-Farber Cancer Institute researcher, has been named a Fellow of the American Association for the Advancement of Science (AAAS) for his contributions to immunology and T-cell activation in human autoimmune disease. The AAAS Fellowship recognizes his distinguished efforts to advance science and its applications.
Researchers found that RA patients treated with rituximab are partially protected by the influenza vaccine, but its effectiveness is drastically reduced in the first 6 months following treatment. The study's results suggest that RA activity was not influenced by the flu vaccine administration.
The International Headache Society has published new research guidelines to stimulate more research into headache treatment and reduce health risks associated with treatment. The guidelines focus on episodic and chronic tension-type headaches, aiming to identify more effective treatments and improve clinical trial safety for patients.
Two large trials found misoprostol tablets non-inferior to intravenous oxytocin for controlling postpartum bleeding, with similar efficacy but increased side effects. The findings support the potential role of misoprostol as a first-line treatment alternative in low-resource settings.
The Center for the History and Ethics of Public Health at Columbia's Mailman School will use the grant to extend its intellectual mission and bring humanities insights to public health challenges. The grant will support a $3,000,000 endowment campaign for faculty chairs, lectures, and research.
A genetic locus on chromosome 7 has been linked to canine compulsive disorder, a condition characterized by repetitive behaviors. The neural cadherin-2 gene, CDH2, is involved in mediating synaptic activity and neuronal adhesion, suggesting a possible connection to human obsessive-compulsive disorder.
Researchers discovered that UV LED light can reduce seizure-like activity in rat epilepsy models by releasing gamma aminobutyric acid (GABA), a natural neurotransmitter. The study suggests that this technique could be translated to human focal epilepsy, offering an alternative treatment option.
Researchers in Brazil develop a GRASP heuristic for efficient school timetabling, solving the NP-hard problem by balancing teacher preferences, student schedules, and resource constraints. The algorithm improves solution quality and reduces building time.
A recent study by Research Australia suggests that relying solely on fat oxidation for weight loss is ineffective. The research found that mice genetically altered to burn fats in preference to carbohydrates still converted unburned carbohydrates into stored fat, ultimately leading to the same weight and body composition as normal mice.
A new study published in the Journal of Alzheimer's Disease suggests that long-term cell phone exposure may protect against and even reverse Alzheimer's disease. The research found that electromagnetic waves generated by cell phones erased brain deposits of beta-amyloid, a hallmark of Alzheimer's disease, in mice.
Scientists developed a nanodragster that can outperform previous nano-sized vehicles and address limitations in controlling small molecule motion. The new vehicle features improved wheels and axle design, enabling better agility and potentially paving the way for more advanced molecular machines.
A new policy paper questions the economic, environmental and logistical basis for billions of dollars in federal subsidies and protectionist tariffs for domestic ethanol producers. The report highlights the environmental threats posed by current biofuels policy and challenges claims that ethanol use lowers greenhouse gas emissions.
Scientists have discovered that the Milky Way's magnetic field is significantly stronger than initially believed, with a strength of at least 10 times greater than the rest of the galaxy. This finding has important implications for various astronomical data calculations and theories, including star formation and cosmology.
Researchers have found an antidepressant, clorgyline, can blunt and reverse muscle enlargement and weakened pumping function associated with heart failure. The drug blocks the action of enzyme monoamine oxidase-A and stops its breakdown of a key neurohormone, norepinephrine.
Researchers have developed a vaccine that appears to reduce leukemia cells in some chronic myeloid leukemia (CML) patients taking the drug Gleevec. The study found significant reductions in residual cancer cells and complete remission in seven patients.
Researchers sequenced over 100 kidney cancer samples, identifying mutations in genes controlling gene expression and chromatin structure. The study reveals genetic complexity in ccRCC, providing insights into diagnosis and treatment options.
A new study predicts that the H1N1 virus can spread quickly on planes, particularly in crowded economy classes. Researchers used mathematical modeling to estimate potential infections during long-haul flights and found that two to five infections could occur on a five-hour flight.
Neuroscientists at MIT have developed a powerful new class of tools that can reversibly shut down brain activity using different colors of light. These 'super silencers' exert exquisite control over the timing of shutdown, allowing researchers to study neural circuits and potentially treat disorders such as chronic pain, epilepsy, and ...
A protein complex called elongator may play a significant role in erasing epigenetic instructions on sperm DNA, enabling the formation of new embryos. This discovery could have implications for stem cell research and cancer treatment.
Researchers have found that Helicobacter pylori directly activates an enzyme in host cells associated with several types of cancer. Chronic H. pylori infection is a known risk factor for gastric cancer, and the discovery may lead to new treatments for this devastating disease.
Researchers discover CoRoT-7b, an earth-like planet, is believed to be the rocky remains of a Saturn-sized gas giant. Computer models reveal that the planet's mass loss and tidal migration led to its transformation.
Researchers found that nine cases of colorectal cancer were diagnosed over 7,626 person-years of observation, with most cancers detected at early stages. The study highlights the importance of close follow-up for patients with a history of advanced adenoma.
Researchers used a special peptide to modify laboratory mice's immune systems, reducing characteristic features of Alzheimer's disease. Anti-inflammatory cells were recruited, dampening the local inflammatory response and boosting plaque-degrading enzyme action.
Counterfeiters are using advanced technology to create fake prescription drugs, including small amounts of real active ingredients and holograms. Law enforcement is responding with new security approaches, but these measures only last around 18 months before counterfeiters can produce new mimics.
A new MMS study examines the Loop Current and its effects on the Eastern Gulf of Mexico, revealing a connection between upper- and lower-layer currents and water mass characteristics. The research provides valuable insights for improving forecasting and predicting the impact of the Loop Current on oil and gas operations.
Researchers discovered a link between diabetes and bone marrow nerve damage that may help treat retinopathy. The abnormal release of stem cells from damaged nerves affects the body's ability to repair blood vessels, leading to blindness.
Camera traps in the Sumatran jungle have captured images of a rare female tiger and her cubs, providing unique insight into their behavior. The tigress and her cubs were seen stopping to sniff and check out the camera trap, giving researchers valuable information about their habitat and population.
Researchers at Tufts University analyzed the calorie content of restaurant dishes and packaged foods, finding that publically available data is often 18% less accurate than their own analysis. This discrepancy could lead to significant weight gain and undermine health initiatives.
Researchers at University of Innsbruck simulate Dirac equation using calcium ion, demonstrating Zitterbewegung and antiparticle behavior. The experiment provides a proof-of-principle for simulating relativistic quantum systems.
Physicists at Iowa State University are starting to see real data from the Large Hadron Collider, a multibillion-dollar particle accelerator. The team is analyzing the data from the ATLAS experiment's silicon pixel detector, which uses 80 million pixels to make precise measurements of particles created in high-energy collisions.
Researchers investigate how our bodies function, including why we chew food to create a firm blob for safe swallowing. Fingerprints are also examined, with tests suggesting they may aid grip and skin flexibility, but the true purpose remains unknown.
Researchers found that higher antiretroviral therapy adherence was associated with lower direct health care costs for HIV-infected adults in South Africa. This decrease in costs is largely attributed to reduced hospital use, saving a median monthly health care cost of $85 per patient.
A new brain scan, diffusion tensor imaging (DTI), has been shown to detect changes in the hippocampus that are associated with memory decline. DTI-MRI scans were found to be more accurate than traditional MRI in identifying changes related to Alzheimer's disease.
Researchers developed a mathematical methodology to reduce biologic variation in laboratory results, improving the sensitivity of detecting physiologic changes. By using multiple paired sets of patient data, they found a substantial decrease in the difference necessary to achieve a given confidence interval.
Researchers Steven Skerlos and James Winebrake argue that government subsidies for plug-in hybrid electric vehicles (PHEVs) should be tailored to specific locations and consumer characteristics. They found that PHEVs are most effective in areas with low-carbon fuel production, high driving volumes, and poor air quality.
Scientists have developed a new bandage that slowly releases nitric oxide, increasing blood flow and regulating body functions. The material is made from zeolites embedded in a water-repellent polymer and has potential applications in therapeutic socks for diabetic patients and organ preservation.
Researchers discovered a protein called MLL that bookmarks highly active genes in cells, enabling rapid gene reactivation after cell division. This finding may help understand how mutated MLL contributes to abnormal cell proliferation and differentiation in leukemia.
A new mathematical model simulates the Big Bang's physical processes, including gas motion, radiation transport, chemical kinetics, and gravitational acceleration. The model's tight coupling enables highly accurate and numerically stable simulations on large supercomputers.