A study found that drugs inhibiting the protein MTOR can impair heart function in patients with ongoing heart dysfunction. Additionally, researchers discovered that deleting the protein 4E-BP1 improved heart function and survival in mice. These findings suggest a potential new therapeutic strategy for improving heart health.
A UBC-BC CfE study found that increased HAART coverage significantly prevents HIV transmission and reduces new diagnoses in British Columbia. The expansion of HAART treatment plays a crucial role in maximizing public health resources.
The National Science Foundation grants LSU a nearly $2 million BIPAS grant to enhance the university's high-speed data communication network, enabling researchers to handle large amounts of data and collaborate globally. The grant will also provide on-demand increases in connectivity for future research needs.
A new study led by Rush University Medical Center indicates that arthroscopic hip surgery can give athletes with hip labral tears the chance to return to their sport within nine months. Most athletes (90%) were able to compete at the same level as before, while 78% returned to their sport.
Janice Morse was inducted into the Sigma Theta Tau International Nurse Researcher Hall of Fame for her extensive contributions to nursing research, particularly in the areas of suffering and comforting. With over 370 publications and numerous awards, Dr. Morse has had a profound impact on the profession.
Researchers monitored Israeli soldiers' neural mechanisms during daily rocket attacks, revealing a dissociative state rather than hypervigilance. This study has significant implications for PTSD therapy, suggesting a neuromarker that can predict chronic PTSD risk.
Researchers at NC State University have developed a stormwater model that accurately predicts pollution impacts from proposed developments. The model uses regional data and can be easily modified for use elsewhere, allowing regulators to make informed decisions about project approvals.
A research project at Universidad Carlos III de Madrid has successfully analyzed cerebral bioelectricity to detect epilepsy. The team developed an algorithm that extracts relevant characteristics from electroencephalograms, allowing for quick detection and classification of epileptic seizures.
A vaginal gel containing 1% tenofovir has been shown to significantly reduce a woman's risk of HIV infection and genital herpes. The study found that the gel was 39% effective in reducing HIV risk during vaginal intercourse, increasing to 54% for women using the gel in over 80% of their sex acts.
A new study by Michael C. Seto and Martin Lalumiere found that adolescent sex offenders are more likely to have atypical sexual interests, such as desire for prepubescent children, than social skills deficits. The researchers also identified social isolation as a key factor in adolescent sexual offending.
Poor children with hearing loss have equal access to cochlear implants, but experience more complications and poor follow-up compliance compared to their higher-income peers. The study found a five-fold greater risk of complications in Medicaid-insured children, highlighting the need for improved access to these life-changing devices.
A study comparing melanoma incidence in Florida to national estimates found that Hispanic men had a 20% higher rate, while female non-Hispanic black individuals had a 60% higher rate. In contrast, female Hispanic patients were 30% less likely to develop the disease.
Researchers at Ohio State University found that breast cancer cells can regulate 14 genes simultaneously in response to estrogen-like compounds like BPA. This mechanism may contribute to cancer development and could serve as a marker for studying environmental exposure.
Researchers at MGH Center for Regenerative Medicine found that reprogrammed induced pluripotent stem cells (iPSCs) retain some characteristics of their cell of origin, which can both assist and complicate future uses. Cellular memories fade with successive generations.
The project focuses on advancing ECBM recovery and providing a pathway to near zero emissions technology from coal-fired power. ECBM involves injecting CO2 into coal seams to displace methane, reducing greenhouse gas emissions by storing CO2 underground.
A study of microbicide gel shows reduced risk of HIV and herpes infections in women, with a 39% effective reduction in HIV risk and 51% effective prevention against genital herpes. The gel contains 1% tenofovir and has the potential to prevent over half a million new HIV infections in South Africa alone.
A new survey method reveals a broader and more diverse array of metal-driven chemical processes in microbes than previously recognized. The research could lead to innovative biofuels and bioremediation technologies.
New guidelines conclude that air travel does not pose a significant risk to cardiovascular health for those with conditions such as angina, heart attack, or abnormal heart rhythms. Passengers should take their medication and follow in-flight oxygen and airport assistance to minimize risks.
Sepsis and septic shock are common complications in general surgery patients, with a death rate of approximately 34% within 30 days. The study identified risk factors for sepsis and septic shock, including age, emergency surgery, and co-occurring illness.
A three-year clinical study will examine the relationship between physical function decline and age-related disparities in breast cancer treatment. The study aims to develop a well-validated instrument for measuring functional decline among senior adults with cancer, ultimately improving breast cancer outcomes for older women.
Scientists discovered that inhibiting a protein called N-cadherin prevents cancer cells from forming groups and migrating. This new approach could lead to more effective therapies for cancer treatment.
Researchers found that subjecting horseradish root stocks to hot water at 47 degrees Centigrade for 20 minutes effectively controls Verticillium and Fusarium pathogens. This simple, safe, and cost-effective method is expected to boost crop yields and improve the quality of commercial horseradish.
Researchers found that intensive auditory training improved sound perception and processing in aging rats, reversing aspects of normal cognitive decline. The study suggests that specially designed mental exercises may benefit people experiencing age-related cognitive decline.
The complete genome of the split gill mushroom has been published, revealing a unique enzyme-based digestive apparatus that enables it to decompose wood. This knowledge can be used to genetically modify the fungus to optimize decomposition processes and improve the properties of wood.
A report examines the relationship between nasal zinc gels and loss of sense of smell in patients. The study found that intranasal zinc gluconate therapy may be associated with a permanent reduction in sense of smell due to chemical injury. Experts recommend increased FDA oversight for homeopathic medications to monitor their safety.
A new study by George Mason University's Center for Climate Change Communication found that framing climate change as a public health problem resonates with people, even those who don't believe in climate change. The research suggests re-framing the issue helps people better understand and relate to the climate problem.
Researchers have developed a new technique combining flexible sigmoidoscopy with optical technologies to detect colon cancer more accurately in women. The test identified subtle changes in tissue that indicate the presence of cancer, providing hope for improving discrepancies in screening accuracy between men and women.
Reducing Ago2-dependent microRNA expression reduces cocaine consumption in mice, suggesting a link between genetic regulation and addiction. Further research is needed to determine which microRNAs control cocaine addiction and whether similar pathways operate in humans.
Duke University researchers have developed a computer program that can predict the next moves of a dangerous bacteria, such as MRSA. The algorithm identifies potential resistance mutations before testing begins, allowing for more effective drug design and potentially saving lives.
Physicists at Oregon State University have discovered a way to use gallium arsenide nanodevices as signal processors at 'terahertz' speeds, enabling faster optical communication and computing. This breakthrough could lead to applications in secure codes and communications, video and audio processing, and even quantum computing.
Research suggests that reducing conflict is not enough to create a positive sibling relationship. Parents should focus on encouraging positive interactions, such as scheduling family activities and teaching problem-solving skills. By doing so, they can help their children develop skills that will benefit them throughout their lives.
A recent study by Hiroki Kurihara's team at the University of Tokyo discovered that Sirt3 helps safeguard mouse embryos against oxidative stress induced by in vitro fertilization and culture. The findings suggest that the negative effects of Sirt3 inactivation can be mitigated by using antioxidants or low-oxygen conditions during IVF.
Researchers from Natural History Museum of Bern reveal courtship behaviors of male parasitoid wasps through antennal structures and coiling behavior. The study, published in BMC Evolutionary Biology, emphasizes the importance of natural history museum collections.
Researchers at Michigan State University have identified a stress hormone in the sea lamprey, which is believed to be one of the earliest forms of cortisol. This discovery provides insights into the evolution of the endocrine system in vertebrates and has implications for understanding human physiology.
A recent study using DNA barcoding has discovered five previously unknown frog species among 30 that were wiped out by a fungal epidemic in Panama. The research also highlights the urgent need to address the biodiversity crisis, with many species disappearing before they can be documented.
A meta-analysis of published evidence reveals painters are at significantly increased risk of developing bladder cancer. The risk increases with length of employment as a painter, and persists even after accounting for smoking and other risk factors.
Researchers found that induced pluripotent stem cells (iPS cells) retain a 'memory' of their tissue of origin, making it harder to differentiate into other cell types. However, additional steps or drugs can erase this memory, making iPS cells comparable to nuclear transfer stem cells.
A pilot program gives patients access to their doctors' notes to improve communication and care outcomes. Meanwhile, a study finds that physicians often neglect contextual information leading to medical errors.
A small study published in Occupational and Environmental Medicine found that regular mobile phone use for at least four years may double the risk of developing chronic tinnitus. The prevalence of chronic tinnitus is increasing, with around 10-15% of people in developed countries affected.
A study by Beth Israel Deaconess Medical Center investigated the effects of transparency through open notes, revealing mixed views among doctors and patients regarding the benefits and drawbacks. The trial involved over 100 primary care doctors and 25,000 patients, who reviewed their medical records online.
Researchers identified a gene regulatory link between early brain development and aging, suggesting 'runaway' development may be detrimental. This process is observed in both humans and macaques, with the latter experiencing accelerated rates, potentially limiting their lifespan to one-third that of humans.
A study published in CMAJ found that a larger waistline and high triglyceride levels significantly increase the risk of coronary heart disease. The combination of increased waist circumference and triglyceride levels was associated with the highest risk of developing the condition.
A study by Caltech researchers found that specific intestinal bacteria can induce MS-like symptoms in animals, suggesting a link between gut microbes and the disease. The bacteria, from the segmented filamentous bacteria group, were able to replicate and cause inflammation in both the gut and central nervous system.
Scientists use four imaging techniques to visualize single cells in detail, cellular substructures, and chemical composition of zinnia cells, indicating an abundance of lignocellulose. This research aims to enhance understanding of cell wall molecular architecture for efficient conversion of biomass to liquid fuels.
A study published in Archives of Dermatology found that individuals with psoriasis who were obese at age 18 had an increased risk of developing psoriatic arthritis. The study also identified other predictors, including younger age at psoriasis onset and larger body surface areas affected by the condition.
Scientists have narrowed down where genes that determine protein and oil content are likely to be found in the soybean genome. Breeders can use these 'signposts' to develop new soybean lines with higher protein and oil levels, enhancing U.S. competitiveness in international markets.
Researchers at Rice University aim to develop an injectable mix of polymers and adult stem cells to regenerate articular cartilage in injured knees and joints. The team hopes to find the optimal formulation of MSCs and growth factors for regenerating new cartilage.
A team of University of Pittsburgh engineers has designed artificial cells capable of self-organizing, performing tasks, and transporting cargo. The cells interact through nanoparticles and can be controlled to perform specific functions, offering a significant step towards synthetic cells that behave like natural organisms.
Researchers at the University of Edinburgh have developed a method to alter viral conditions, reducing mutation and building resistance. This approach can target multiple viruses simultaneously and is being explored for use in treating influenza.
The Journal of NeuroVirology will cover new areas in neurovirology, including non-viral infections affecting the central nervous system. Springer's acquisition will support the International Society for NeuroVirology and advance knowledge in the field.
Two studies examine the effects of oral steroids and propranolol on infantile hemangiomas, revealing potential side effects and complications. Researchers aim to develop safer treatment options for this common childhood skin disorder.
The New York Center for Astrobiology will expand its research with a new NASA grant, searching for the building blocks of life beyond Earth. Researchers study the chemical and physical conditions on Earth that gave birth to life and apply this information to search for similar conditions elsewhere in our solar system.
Researchers discovered an adaptation in Eastern mole blood that allows for more efficient carbon dioxide transport, facilitating burrowing. The 'super hemoglobin' enables moles to thrive underground, overcoming oxygen and carbon dioxide challenges.
Healthcare worker seasonal influenza vaccination rates remain low, with a study suggesting combined education and improved vaccine access boost coverage. Long-term care home workers showed significant increases in immunization rates following targeted campaigns.
Research identifies APOL1 gene variants associated with increased risk of kidney disease in African-Americans. The genetic variants may have evolved as a survival mechanism against parasitic disease in Africa.
A recent study found that using a vaginal microbicide with an antiretroviral drug called tenofovir significantly reduced HIV infections among women. The study involved 889 women from South Africa and found that those who used the gel before and after sex had 39% fewer HIV infections compared to those who used a placebo gel.
Researchers found that mice lacking MTOR in their heart muscle cells developed a fatal heart condition, highlighting the potential adverse effects of MTOR inhibitors on heart health. Deletion of 4E-BP1 improved heart function and survival, suggesting a new therapeutic strategy for improving heart function in patients with heart failure.
A study found that trauma patients who received intraoperative cell salvage—a process collecting and re-infusing their own blood—had fewer allogeneic blood product units transfused compared to those without this procedure. This resulted in lower costs, with a cost difference of $968 per patient.
Researchers found that women who used more air fresheners and products for mold and mildew control had a higher incidence of breast cancer. The study suggests that cleaning products may contribute to breast cancer risk, highlighting the need for further investigation into this potential link.
A new study using a global model confirms that implementing cool roofs and pavements in cities can cancel the heating effect of up to two years of worldwide carbon dioxide emissions, equivalent to taking 300 million cars off the road. This can help delay warming and mitigate global climate change.