Researchers found that sustained virologic response (SVR) prevents esophageal varices in patients with compensated hepatitis C (HCV)-induced cirrhosis. This study suggests that endoscopic surveillance can be safely delayed or avoided in these patients, reducing unnecessary invasive procedures.
Researchers at URMC discovered a defect in cellular pathways regulating bone formation at the stem cell level, leading to premature closure of skull sutures and craniosynostosis. This finding sheds light on the complex system controlling stem cell fate and has implications for understanding skeletal disorders and cancer.
A new rule at Massachusetts General Hospital has led to a significant decrease in unnecessary imaging exams for patients. The change encourages physicians to directly log into the system, reducing low-yield exams from 5.4% to 1.9%.
Einstein College of Medicine receives significant NIH funding to continue its Diabetes Research and Training Center, supporting research into central nervous system role in diabetes, epigenetics, and diabetic complications. The grant enables the development of new therapies for prevention or treatment of diabetes.
Agricultural Research Service scientists have developed a new model to manipulate vitamin D levels in young calves, which could help establish the optimal amount needed for growth and health. The model uses vitamin D injections to control levels in the bloodstream of neonatal dairy calves.
MSU environmental scholar Bob Walker leads research expedition along western Transamazon Highway to study the impact of tree loss on the Amazon. The team will document logging activity and interview workers in the logging industry and longtime residents about the effects of development.
Hypertension control increased from 27.3% in 1988-1994 to 50.1% in 2007-2008, with blood pressure decreases among patients with hypertension. However, hypertension prevalence has not decreased in recent years and remains high at approximately 65 million individuals in the US.
Researchers have developed a new technique to study the structural properties of tissues by sucking cells into a pipette, providing information on adhesion and elasticity. This approach complements existing methods and allows for measurements on living tissue in its natural environment.
A recent survey found that only 6% of Toronto high schools train students to use an AED and perform CPR. Despite the benefits of increased survival rates, many students lack this essential skill.
A new assessment tool, the Malawi Developmental Assessment Tool (MDAT), has been developed and evaluated for use in rural African settings. The tool accurately identified children with neurodisability and demonstrates high reliability and accuracy, making it a valuable resource for researchers and healthcare providers.
A NIRCam engineering test unit has arrived at NASA's Goddard Space Flight Center to undergo a year-long testing process. The unit, built by Lockheed Martin, will simulate the flight unit's functions before the actual instrument is integrated into the James Webb Space Telescope.
Researchers discovered that shoaling fish coordinate their movements more frequently when under threat to reduce the risk of being targeted. This 'oddity effect' drives better synchronization in group movement, making it harder for predators to single out individual targets.
A new study reveals that drains are a significant vector for the development of lymphatic filariasis and malaria in Dar es Salaam. The researchers found that simple environmental management interventions can help reduce mosquito-borne disease transmission and promote a healthier environment.
Non-Suicidal Self-Injury (NSSI) is a common practice amongst adolescents, with medical providers uniquely positioned to detect its presence. Janis Whitlock's article discusses the epidemiology and care of adolescents undertaking NSSI, highlighting the need for standard assessment practices and effective treatment regimes.
Researchers found that specific bacterial signatures were associated with polyps, early lesions that can develop into colon cancer. The study suggests the development of non-invasive screening tests and diet-based prevention regimens to reduce CRC risk.
Researchers at Rice University have discovered a way to extract hydrogen atoms from graphane, creating spaces that resemble quantum dots. This breakthrough enables precise control over the semiconducting properties of quantum dots, with potential applications in advanced optics, single-molecule sensing, and nanoscale circuitry.
Research suggests that using lubricants during receptive anal intercourse can increase the risk of rectal sexually transmitted infections (STIs), including HIV. A study involving nearly 900 men and women found that those who used lubricants were three times more likely to have a rectal STI.
Researchers in Spain have developed a method to create highly accurate three-dimensional models of historical buildings using laser scanners and software. This technology reduces the time spent on field work by up to 75% while capturing thousands of times more information than conventional methods.
The University of Pittsburgh will conduct human trials for three innovative regenerative medicine programs aiming to replace scars and defects with healthy tissues. The projects, if successful, could lead to interventions benefiting civilians as well.
A new study by Georgia State University professor Paul J. Ferraro found that saving rainforests and protecting national parks reduced poverty in Costa Rica and Thailand in the long term. The research suggests conservation efforts may provide economic opportunities through tourism and infrastructure development.
Research published in PLOS Medicine found that the Mediterranean G6PD variant protects against Plasmodium vivax infection in Afghan refugees. The study suggests that G6PD deficiency may be retained in human populations due to its protective effects against Plasmodium vivax malaria.
Six collaborative research projects aim to develop treatments, vaccines, or antimicrobial products for gastric flu, hepatitis B, dengue fever, and tuberculosis. Researchers will work together to shed light on bacterial signaling pathways and train immune cells to overcome viral infections.
Dr. Castellani's work challenged the traditional view of Alzheimer's disease pathogenesis and highlighted the beneficial effects of amyloid formation. He received the award for his outstanding contribution to understanding the neuroprotective role of amyloid-β protein precursor and amyloid-β.
Researchers at UT Southwestern identified 172 compounds with potential as new anti-malarial drugs, offering a promising tool in combating the disease. The compounds were discovered through high-throughput screening of a vast chemical compound library.
The National Oceanography Centre (NOC) has partnered with the Met Office to upgrade the Porcupine Abyssal Plain sustained observatory (PAP-SO), a key European ocean observatory. This collaboration aims to advance scientific knowledge of the ocean and improve climate prediction by integrating meteorological and ocean data.
A team of researchers discovered that a supermassive black hole at the center of the most massive local galaxy, M87, is displaced from its expected location. The finding suggests that supermassive black holes may be commonly offset from their host galaxy centers due to previous mergers or interactions with jets.
Researchers used tree-ring data to reconstruct northwest Africa's climate history, finding frequent and severe droughts during the 13th-16th centuries and late 20th century. The region's 20th-century drying trend matches climate models' predictions, while regional drought patterns differ across Morocco, Algeria, and Tunisia.
Researchers at Heidelberg University Hospital have identified new mutations in the SHANK2 gene that contribute to autism and mental retardation. The study found that a correct inner structure of nerve cell synapses is necessary for normal language, social competence, and cognitive development.
A Montreal study reveals that more than 70 percent of bottled water samples contain heterotrophic bacteria counts above the recommended limits set by the United States Pharmacopeia. High microbial counts were found in several famous brands, with some exceeding 100 times the permitted limit.
Research reveals that termite mounds in the African savanna enhance plant and animal activity at a local level, while their even distribution maximizes ecosystem-wide productivity. The findings suggest that these humble creatures are having a massive impact on the system from below.
Pioneering AIDS researchers Dr. Mark Wainberg and Dr. Norbert Gilmore argue that the current ban on gay men donating blood is no longer justified. They suggest allowing only those in stable, long-term monogamous relationships to donate, while maintaining the ban on those with multiple partners.
Researchers at Tufts University School of Medicine highlight the carcinogenic effects of endocrine-disrupting chemicals (EDCs), which can cause harm during organ formation. EDCs, such as bisphenol A, have been linked to increased cancer rates, obesity and infertility.
New research from the Microbicide Trials Network indicates that some lubricants have toxic effects on cells and rectal tissue. The study's findings support IRMA's calls for safer lubricant options, emphasizing the importance of condom use with compatible lubricants to prevent HIV transmission.
Researchers from UC Davis Health have found E. coli O157:H7 in fecal samples of wildlife species common to California's Central Coast region, including cowbirds, coyotes, crows, mice, and feral pigs. While the presence of the bacterium is rare, it suggests there are potential sources of pathogen movement that need to be assessed.
A new study from the University of Bristol reveals that parents' physical inactivity can influence their children's TV viewing habits. The research found that higher parental TV viewing was associated with an increased risk of high levels of TV viewing for boys and girls.
A new study reveals that high levels of 'good' HDL cholesterol may not be beneficial for all patients and can even increase the risk of recurrent coronary events. Researchers identified a subgroup of patients with elevated HDL cholesterol and CRP who are at high risk, suggesting that genetics and environmental factors influence the pro...
Scientists have identified a synergistic relationship between a fungal pathogen and RNA viruses from the family Dicistroviridae as contributing factors to Colony Collapse Disorder. The presence of these pathogens in sick colonies is a strong predictor of collapse, with higher levels of the fungus compromising gut wall integrity.
Holly Michael, assistant professor at the University of Delaware, has received the Ralph E. Powe Junior Faculty Enhancement Award to support her research on eutrophication and groundwater interactions. Her study aims to identify subsurface zones where nutrient transformations occur in Indian River Bay.
A new laser-balloon catheter successfully interrupted irregular electrical pulses in patients and pigs, offering a potential new treatment for abnormal heartbeats. The treatment achieved 100% accuracy in clinical trials and had long-lasting effects, making it a promising alternative to traditional ablation procedures.
Research by Robert M. Pringle and Todd M. Palmer reveals that termite mounds significantly enhance plant and animal productivity at local levels, while their even distribution maximizes ecosystem-wide biomass. The ordered distribution of these mounds creates an optimized network of plant and animal output.
The 'manifesto' outlines eight key points, including NTDs are tool ready with cost-efficient interventions, yet tool deficient, requiring sustained international support and community involvement to achieve global NTD control. The authors emphasize the need for urgent, renewed, and innovative efforts to tackle NTDs.
A recent study found that at least 90% of adolescents with mental illnesses reported experiencing stigma, leading to feelings of shame and isolation. Parents and schools can play a crucial role in mitigating these stigmas by promoting acceptance and inclusivity.
Researchers discovered little difference in current health status between normal-weight and overweight people across all age groups. The study also found that people with a BMI in the overweight range are generally not at a higher risk for current health problems compared to those of normal weight, regardless of age.
A study published in Trials highlights the widespread issue of publication bias, where favourable results are selectively published, leading to delays in implementing effective treatments. This can result in patients being prescribed futile or harmful treatments, as was the case with a drug used to prevent irregular heartbeats.
Researchers at Michigan State University found that osteopathic manipulative medicine significantly reduced hospital stays for pneumonia patients. Additionally, the study showed a slight decrease in intravenous antibiotics needed and respiratory failure.
Desert locusts that swarm together have larger brains with altered proportions compared to solitary locusts. Their bigger brains are thought to help them cope with the challenges of living in large groups and finding varied food sources.
A research review found that patients use the internet to get health answers but only consult healthcare providers 28-41% of the time. The GATOR approach encourages healthy surfing by identifying trustworthy websites and evaluating information for accuracy and readability.
A rare parasitic infection called paragonimiasis has been diagnosed in six people who ate raw crayfish from Missouri streams, according to Washington University School of Medicine. The infection causes fever, cough, chest pain, and fatigue, but is easily treated with an oral drug, praziquantel.
Research reveals that high-strain tendons, like the Achilles tendon, repair themselves less frequently due to increased mechanical damage. This study sheds light on the increased susceptibility of certain tendons to injury during aging.
A study of over 10,000 breast cancer cases reveals the long-term prognosis for ER-negative disease subtypes is better than previously thought. The research also identifies two sub-types within triple negative tumors with differing outcomes.
Rensselaer Polytechnic Institute has been awarded a four-year $2.45 million grant from the New York Stem Cell Science Program to create an upstate center of excellence for basic stem cell research. The grant will be used to build sophisticated laboratories with high-throughput culture and imaging equipment, enhancing stem cell research...
A study published in JAMA found that respiratory syncytial virus (RSV) is the most commonly detected virus among Kenyan children with severe pneumonia. RSV was associated with increased risk of admission with severe disease, suggesting that vaccination may offer significant public health benefits.
Charles Shagi, a community educator from Tanzania, received the second Omololu Falobi Award for Excellence in HIV Prevention Research Community Advocacy. His work empowers women and their communities to advocate for themselves and become partners in HIV prevention research trials.
Researchers discover mutant strain of gum disease-causing bacteria that can activate autophagy, a cellular process that breaks down waste products and plaques associated with neurodegenerative diseases. This finding could lead to novel therapeutics for treating Alzheimer's, Parkinson's, and other diseases.
Embryonic stem cells can switch between different cell types, indicating a potential for pluripotency. Researchers hope to understand this process to create specific cell types in the lab.
The Canadian Medical Association Journal suggests relaxing the ban on male blood donors who have had sex with men, citing a significant decrease in false negative test results. The proposed change could lead to an expansion of the blood donor pool, resulting in more units of blood available for transfusions.
Scientists have developed a new method to directly measure body temperatures of extinct vertebrates, revolutionizing our understanding of ancient environments. The 'clumped-isotope' paleothermometer method analyzes fossilized teeth and bones to determine temperature ranges during the animals' lifetimes.
Researchers collecting mollusk specimens from the Gulf Coast will analyze growth rings in shells to determine how quickly harmful compounds from the oil become incorporated into the animals' bodies. They will also test for hydrocarbons in tissues and measure changes in growth rate and survivorship.
Researchers have found a statistically significant association between enteroviral infection and diagnosis of type-1 diabetes in children, with 83% of patients testing positive for enteroviral DNA. The study suggests that different enterovirus types may represent a significant biomarker for early-stage juvenile diabetes.
Researchers have developed a unique core and shell nanoparticle that uses far less platinum yet performs more efficiently and lasts longer than commercially available pure-platinum catalysts. The new catalyst generates 12 times more current than existing models, offering a promising advance in fuel-cell technology.