Researchers found that NSAIDs inhibit COX-2, reducing tumor growth and metastasis. However, the safety of these drugs during pregnancy remains uncertain due to the complex changes occurring in the body after childbirth.
A new treatment developed at Tel Aviv University uses laser-treated bone marrow stem cells to help restore heart function and health. The procedure significantly reduces heart scarring after an ischemic event by up to 80 percent, offering a safer and quicker alternative to existing options.
A recent study investigates corn silage hybrid responses to seeding rates, finding all hybrids require similar growth rates at four seeding rates. The study suggests that seeding rates should not be adjusted for different hybrid types.
Researchers studied electronic properties of bilayer graphene, revealing unique effects due to electron-electron interactions. The material's quasiparticles exhibit chiral symmetry, making it an exciting material for electronic applications.
Bumble bees, like honey bees, are important pollinators of native plants. Entomologist James Strange is studying a generalist named Bombus huntii that could be used in greenhouses in the western United States as a replacement for declining B. occidentalis populations.
A recent investigation found that a common strain of C. difficile, known as BI/NAP1, is endemic in Chicago-area acute care hospitals, putting patients at risk for severe disease. The outbreak strain was spread through patient transfers between healthcare facilities.
The study shows that the fault involved in the 2010 El Mayor-Cucapah earthquake was simple on the surface but complicated at depth. Researchers used a combination of GPS data, remote sensing techniques, and seismological data to produce an extremely well-resolved model of the earthquake.
A study by Washington State University-Vancouver and the University of California-Davis investigated the relationship between human phosphorus sources and aquatic nutrient levels. The research found that a small area contributed to most phosphorus input from human sources, with fertilizer and livestock manure being key drivers.
A Baylor University researcher explores the relationship between church members' educational backgrounds and their approach to reading the Bible. He found that those who attended college are less likely to interpret the Bible in a literal sense when surrounded by more educated congregants.
Researchers have discovered how TB drug pyrazinamide effectively shortens the required duration of TB therapy. The drug acts on latent TB bacteria that exist in an acidic environment, converting to its active form to bind and block vital protein RpsA, ultimately killing the bacteria.
The FASEB MARC Program has announced the winners of its 2011 Leadership Development and Grant Writing Seminar, with a total of $61,050 in awards to support underrepresented graduate students and postdoctoral fellows. The program aims to increase highly-trained underrepresented scientists in leadership positions.
TrES-2b's extremely dark surface is attributed to its high temperature and the presence of light-absorbing chemicals. The planet emits a faint red glow due to its heat, revealing it's not pitch black despite its low reflectivity.
The University of Colorado Cancer Center has successfully genetically sequenced the most prevalent type of bladder cancer, urothelial carcinoma. The team discovered mutations in genes responsible for chromatin remodeling, which are similar to those found in other cancers.
Researchers found that molecular motor proteins fold in on themselves to prevent unnecessary energy consumption, controlling cargo transport. This discovery may open new avenues for treating neurodegenerative diseases such as Alzheimer's and Huntington's.
Researchers have cultured and identified a new type of fungus, Archaeorhizomycetes finlayi, found in soil for millions of years. The fungus, which is slow-growing and produces spores only in soil, may play a role in breaking down dead plants.
A recent study tracking chimpanzee brain development found that both humans and chimps have immature forebrains at birth. The study's findings suggest that this developmental delay may provide an extended period of plasticity, enabling both species to develop complex social skills.
Researchers found that cocaine addicts prioritize immediate rewards over delayed ones, regardless of the commodity involved. This study has implications for developing drug treatment programs based on incentives for delaying drug use.
Researchers aim to develop new post-stroke therapy by repairing the blood-brain barrier, which prevents harmful substances from entering the brain. If successful, this could lead to positive therapeutic outcomes for ischemic stroke patients who may have missed the limited 3-hour tPA window.
Radiofrequency ablation (RFA) successfully eradicates precancerous cells and intestinal metaplasia in patients with dysplastic Barrett's esophagus, with over 90% of patients showing complete clearance after three years. The procedure offers a minimally invasive alternative to surgery, reducing complication rates and mortality.
Researchers have developed a new technique to manipulate surface plasmons in real time, enabling the creation of ultra-small-scale optoelectronic devices and systems. This innovation allows for on-the-fly control and flexibility in nano-system design and manufacture.
The study creates a worldwide map of coral reefs, highlighting areas with high biodiversity and low stress, to inform conservation efforts. The researchers used fuzzy logic and publicly available data to group reef systems into clusters based on their stress exposure grades.
A history of depression is linked to a 29% increased risk of total stroke in women, according to new research. Women who used anti-depressant medication also had a higher risk of stroke, likely due to underlying vascular disease or inflammation.
An international team led by a visiting researcher at IU has formally named a new class of fungi, Archaeorhizomyces, previously only known through DNA sequencing. The discovery estimates up to 250 species within the class and sheds light on their ecological roles in terrestrial ecosystems.
Researchers investigated potential effects of G-CSF on chromosomes in healthy PBSC donors and found no replication asynchrony or atypical abnormalities. The study concludes that G-CSF mobilization process is safe for healthy stem cell donors, supporting its use in transplants.
Researchers discussed using Doppler weather radar to track bat behavior and effectiveness of acoustic deterrents in reducing bat fatalities at wind farms. Aeroecology also explored the role of atmospheric conditions in flight behavior, with studies on golf courses as potential habitats for roosting bats and the importance of insectivor...
A NIH-led team has discovered a method to guide the evolution of powerful HIV-neutralizing antibodies, which could lead to the development of an effective vaccine. The researchers used deep sequencing and bioinformatics techniques to decipher the genetic data of immune cells that produce these antibodies.
Researchers at Stanford University School of Engineering used new measurement technologies and analytical mathematics to study the neurological explanations for movement planning. They found that neural activity varies depending on direction, distance, and speed of a pending movement, departing from previous theories.
Researchers at National Physical Laboratory develop a model peptide sequence dubbed GeT that transports genetic material into human cells, overcoming poor cell membrane permeability. This approach holds promise for gene therapy in treating defective genes such as cancer.
A study at Joslin Diabetes Center and Children's Hospital Boston found that 'good' brown fat is prevalent in leaner children, increasing until puberty and then declining. Boosting brown fat activity may be an effective approach to combating childhood obesity.
Researchers aim to create a 'virtual rat' model to predict and understand physiological function and disease, filling a gap in understanding complex diseases. The Virtual Physiological Rat (VPR) project will use computer simulations to translate findings from animals to humans, targeting diseases like hypertension and heart failure.
Researchers sequenced the genomes of mealybug-dwelling bacteria, revealing a level of molecular integration between species that has never been seen. The study found that the bacteria have evolved to trade metabolites and enzymes to produce essential amino acids, with one genome shrinking to its smallest ever described size.
A new computational model developed by researchers at Ohio State University can forecast where cholera outbreaks are likely to occur in Haiti. The model takes into account various factors, including environmental conditions and human contact, to identify typical patterns of cholera outbreaks and hotspots where control efforts are needed.
Researchers at Berkeley Lab have demonstrated a technique to control the curved trajectories of Airy beams in real-time, enabling fast-as-light communication systems and optoelectronic devices. This breakthrough uses plasmonic Airy beams to manipulate surface plasmon polaritons, opening doors to new technologies in nano-photonics, biol...
Researchers have created a new model of ALS using human cells from autopsied tissue, finding that astrocytes secrete toxic factors that cause nerve cell degeneration. The study suggests that inflammatory responses and SOD1 function contribute to both sporadic and familial ALS.
Researchers develop method to extract ammonium from liquid animal manure using gas-permeable membrane technology, removing 50% of dissolved ammonium in 20 days. The captured ammonia can be converted into ammonium sulfate fertilizer, potentially offsetting the cost of removal and mitigating environmental pollution.
Researchers designed a material that can make energy-storing hydrogen gas 10 times faster than natural enzyme, using inexpensive metals. The synthetic material works at 100,000 molecules of hydrogen gas every second and has potential applications in fuel cells.
A new study from Loma Linda University found that excess body fat in elderly individuals decreases life expectancy. Maintaining a normal weight between 18.5 and 24.9 is considered ideal, while overweight and obesity are associated with increased risk of mortality.
The museum's new dinosaur hall features a unique 78-million-year-old fossil that shows evidence of live birth in an adult plesiosaur and its developing embryo, resolving a long-standing mystery in the field. The research establishes that plesiosaurs gave birth to live young, rather than laying eggs on land.
The La Jolla Institute's new RNAi Center will focus on understanding the genetics behind disease processes and developing new therapies to treat disease. The Center aims to make key discoveries about how the immune system recognizes bacteria and viruses and fights infections.
A clinician-scientist team, led by Joseph M. Miano and Craig Benson, has created a model resource that identifies and outlines the function of common mutations in the human genome. They believe this information will help guide the development of new prevention and treatment options for diseases.
Researchers identified five core themes for successful implementation of evidence-based practices in Intensive Care Units (ICUs) to reduce Methicillin Resistant Staphylococcus aureus (MRSA) infections. Engaging front-line staff, building multi-disciplinary teams, and acquiring top management support are critical commonalities.
Engineers create epidermal electronic systems (EES) with miniature sensors, light-emitting diodes, tiny transmitters and receivers to measure human physiological data. The devices are seamlessly integrated onto the skin, providing opportunities for non-invasive medical monitoring.
Researchers at the University of Missouri found that urban Chinese households save significantly more than American households, driven by education-related motives. The study attributes this disparity to cultural values emphasizing education and the lack of social-welfare programs in China.
Researchers at Johns Hopkins Bloomberg School of Public Health have decoded the workings of Pyrazinamide (PZA), a critical TB drug. PZA inhibits trans-translation, a process essential for cell survival under stress conditions, making it effective against non-growing bacteria called persisters.
Researchers at Stanford University have developed a new dual-action protein that effectively prevents the formation of blood vessels by targeting two key chemical receptors. This breakthrough could lead to more effective cancer treatments and potentially benefit diseases such as macular degeneration.
Researchers found evidence of gas outflows from the supernova ancestors, suggesting they don't originate from white dwarfs. This discovery is crucial for understanding Type Ia supernovae and their immense luminosity.
Researchers have engineered bacteria to withstand high levels of mercury and remove it from their surroundings, providing a potential technology for bioremediation. The bacteria were able to grow in extremely high concentrations of mercury and remove over 80% of it in five days.
Researchers at Duke University have demonstrated a theoretical ability to significantly increase the efficiency of ships by creating a 'fluid flow cloak' that tricks the surrounding water into staying still. The cloak uses porous materials and tiny pumps to push flowing water along, greatly reducing the energy needed to propel vessels.
A team of researchers from the University of Valladolid analyzed 40 brands of beer and found that dark beer contains more free iron than pale and non-alcoholic beers. The average free iron content in dark beer was 121 ppb, while pale beer had an average of 92 ppb.
Researchers found that Arctic ice under current climate conditions is as likely to expand as it is to contract for periods of up to a decade. The study suggests that climate change and variability work together to accelerate sea ice loss, but temporary stabilization or expansion may occur.
A study found a clear association between after-hours care clinic accessibility and reduced emergency department use. The clinic saw a 40% decrease in semi-urgent patients visiting the ER, suggesting better resource allocation.
A study published in PLOS Genetics found that there are significant differences in metabolites between men and women, which may lead to the development of gender-specific treatments for certain diseases. The researchers used metabolomics and genetic data to identify key biomarkers, paving the way for new therapeutic approaches.
Estrogen has been found to help regulate white blood cell activity, preventing them from sticking to blood vessel walls and causing vascular damage. This natural mechanism could have important implications for understanding and treating cardiovascular disease.
The DYCAST program successfully predicted where 81.6% of human cases of the West Nile virus would arise in California in 2005. By using biological parameters, the model identified high-risk areas with a risk 39 times higher than low-risk areas, allowing for targeted mosquito control and reduced human illness.
Scientists discovered that the intestinal membrane receptor protein, GC-C, is also expressed in critical brain areas. The study found that GC-C's activation amplifies dopamine responses, leading to hyperactivity and attention deficits in mice. Treatment with a PKG activator reversed these behavioral problems.
Climate change is causing significant changes in polar ecosystems, particularly in the Arctic where permafrost thawing affects land and water ecosystems. This can lead to increased nutrient levels, altered stream networks, and changed habitats for plants and animals.
A case study published in Cortex reveals that severe damage to the hippocampus resulting from lack of oxygen in infancy can hinder episodic memory recall. In contrast, semantic memory remains intact, supporting the theory that different areas of the brain are responsible for distinct types of memory.
Researchers created a device platform that combines electronic components for sensing, medical diagnostics, communications, and human-machine interfaces on an ultrathin skin-like patch. The circuit bends and stretches like the skin, allowing for comfortable wear and freedom of movement.