Researchers have identified a novel mechanism by which Bartonella bacteria manipulate host cell signaling, prolonging cell lifespan and contributing to chronic infection persistence. The study reveals the role of protein BepA in binding adenylyl cyclase, leading to increased cAMP production and preventing host cell death.
Researchers found that geckos gained and lost sticky toepads independently in various groups, with the loss occurring in species living on sandy dunes. The study's findings shed light on how geckos' unique adaptation evolved over time, providing insights for developing new adhesive technologies.
Research reveals that smoking, head injury, and pesticide exposure may increase the risk of REM sleep behavior disorder, a rare condition where people act out their dreams. The study also found that farming work and lower education levels were associated with a higher risk of developing the disorder.
Researchers have developed a technique to reprogram adult cells from patients with limb-girdle muscular dystrophy into stem cells, which can then be genetically modified and transplanted into mice. The study shows promise for treating this rare form of muscular dystrophy.
Researchers analyzed fossilized teeth to reveal that A. sediba ate harder foods like trees and bushes, unlike most other hominids who focused on grasses and sedges. This diet was confirmed by analysis of microscopic particles trapped in tooth tarter, suggesting the individuals avoided open grasslands.
Scientists at Max Planck Institute have discovered a molecular link between telomerase and the Wnt/β-signalling pathway, which regulates telomere length in stem cells and cancer cells. This regulation mechanism could lead to the development of new treatments for human tumours.
A study published in the American Journal of Public Health found that community racial and ethnic composition affects obesity rates, with Hispanic communities associated with a 21% higher obesity rate and non-Hispanic whites with a 23% higher rate. In contrast, communities with high concentrations of non-Hispanic Asians saw lower obesi...
Researchers detected significant differences in brain development in high-risk infants who developed autism starting at age 6 months. White matter tract development was found to be the key difference between those with and without autism.
A study by San Francisco State University suggests that gay dads' lifestyles may change in ways that protect them from risky sexual behavior after becoming parents. Many couples reported a decrease in sex frequency but found this acceptable, while others remained committed to their monogamous relationships.
Researchers at Northwestern University have created an animal model that spontaneously develops rheumatoid arthritis and is predisposed to atherosclerosis. The model allows scientists to examine the systemic influence of inflammatory arthritis on the development of heart disease, with promising results from treatment with Enbrel.
The US research vessel R/V Roger Revelle is participating in a nine-day port call in Da Nang, Vietnam, as part of the Joint Vietnam-US Research Program. The program aims to improve forecasts on coastal ocean circulation and land-ocean interactions in the Vietnamese East Sea.
A new analysis found that over two-thirds of recently approved pesticide active ingredients have roots in natural substances. Scientists have discovered that biological and natural products-based pesticides are a rich source of new active ingredients.
Researchers have found that 'broken heart syndrome,' a condition causing temporary heart failure after severe emotional stress, may actually protect the heart from extremely high levels of adrenaline. The study suggests a switch in the heart's response to adrenaline might have evolved to prevent overstimulation.
Researchers at Mayo Clinic have successfully used aptamers to stimulate regeneration and repair of nerve coatings in mice with multiple sclerosis. The finding suggests new possible therapies for MS patients, providing hope for a potential cure or treatment.
Researchers at Newcastle University used biomechanical motion capture to analyze pigs' gait and identify those at risk of becoming lame. The study aims to develop a farmer-friendly system to predict leg problems and reduce lameness, improving health and welfare on UK farms.
A new Geosphere study uses virtual fieldwork to analyze terrain data from the 2010 Haiti earthquake, revealing evidence of active faulting and ancient surface rupture. The research also explores the provenance of sandstones in the Colton Formation and the interactions between the Seattle and Saddle Mountain faults.
Researchers at Massachusetts General Hospital have developed tiny magnetic coils that can modulate neural activity, reducing symptoms of Parkinson's disease and other movement disorders. The study found that the coils can selectively target specific populations of neurons, minimizing effects on non-targeted cells.
A new study has found that lung nodule matching software can significantly improve radiologists' efficiency, with an average increase of almost two-fold compared to manual matching. The software correctly matched nodules at an accuracy rate of 79-92% while reducing the time required for matching from 1 second to under 6 minutes.
Georgetown University Medical Center will establish the Center of Excellence for Health Disparities, focusing on eliminating health disparities among minority populations in Washington, D.C. The center aims to reduce chronic diseases such as breast cancer and stroke through research, education, and community engagement.
A new study presented at The Endocrine Society's 94th Annual Meeting has found that monitored vitamin D therapy is safe for patients with primary hyperparathyroidism and vitamin D deficiency. Vitamin D treatment helped lower parathyroid hormone levels, but did not raise calcium blood levels in patients.
A survey of Grade 5 students in Alberta found that kids who help with meal preparation are more likely to eat healthier foods and have better diets. Children who cooked showed a greater preference for both fruits and vegetables, and were more confident about making healthier food choices.
A study by the Rey Juan Carlos University found that objective corruption data for Spain is higher in politics than administrative-official institutions, but Spaniards perceive corruption as a major issue. The researchers attribute this discrepancy to cultural and institutional factors.
BioImageXD is an open-source software that enables the analysis of cell and tissue functions by rendering microscopic images into three-dimensional models. The software allows scientists to study how molecules move on cell surfaces, bond together, and analyze cancer cells' behavior.
A novel diagnostic test has been developed to accurately detect Group B Streptococcal infection in babies, allowing for quicker treatment and potentially reducing mortality rates. The test detects the presence of a specific gene in the bacteria, which is an important disease-causing factor.
Researchers found that a diet enriched with DHA and curcumin preserved walking ability in rats with spinal-cord injury, while a Western diet caused measurable walking problems. The study suggests that dietary supplements may help repair nerve cells and maintain neurological function after degenerative damage to the neck.
A study published in Computers in Human Behavior found that editing social media profiles on Facebook increases self-esteem, while using MySpace leads to higher levels of narcissism. Researchers also discovered that the differences in site format between MySpace and Facebook may contribute to these findings.
Researchers use Lonestar supercomputer to create nearly 100,000 models of one galaxy, representing the range of possible ways stars can move. They find that dark matter is more spread out at the edge of the galaxy than previously thought, with a fluffier distribution but the same total amount.
Research finds green rust played a crucial role in oxygenating the Earth's atmosphere, scavenging heavy metals like nickel from water. The mineral's high reactivity makes it promising for cleaning up polluted sites and removing toxic metals.
Raj Patel argues that understanding hunger and malnutrition requires examining systems and institutions holding power over food. Food sovereignty is advocated as a means to achieve food security and eradicate undernourishment, prioritizing women's rights and community control.
Researchers found that crowd disasters are not caused by individual panic, but rather amplifying feedback and cascading effects. They introduced a new scale to assess criticality of conditions in the crowd, aiming to prevent disasters before they occur.
A study by the University of Kentucky Markey Cancer Center found that cancer patients experienced significant improvements in pain, stress, and nausea after one Jin Shin Jyutsu session. The study included 159 patients who reported a mean decrease of three points for stress and two points for both pain and nausea.
Caltech engineers enable focusing of light deep into biological tissue, opening up possibilities for non-invasive diagnoses and treatments. The technique uses ultrasound waves to shift the frequency of light, allowing for image creation without scattering effects.
A patient registry has yielded crucial data on the clinical features and outcomes of fibromuscular dysplasia (FMD), a non-inflammatory vascular disease. The study found that 91% of patients are women diagnosed in their prime of life, with an average delay in diagnosis of four years from symptom onset.
Neil Gehrels, a NASA astrophysicist, receives the Committee on Space Research Harrie Massey Award for his pioneering contributions to gamma-ray astronomy. The award recognizes his leadership role in advancing astronomers' understanding of gamma-ray bursts.
Researchers at the University of Michigan successfully tested a lab-on-a-chip technology to detect low levels of trichloroethylene in homes near Hill Air Force Base. The device, tailored to detect any contaminants, has potential applications for industrial chemicals, cancer biomarkers, and explosives detection.
A multicenter trial showed that nearly half of young patients with early-stage Hodgkin lymphoma can be cured without radiation or intensive chemotherapy, maintaining excellent long-term survival. The study's findings suggest that patients with favorable-risk disease may benefit from minimal treatment approaches.
A study using pregnant mice found that BPA exposure changes the way genes respond to estrogen in adulthood, potentially explaining increased incidence of estrogen-related disorders. This can lead to conditions like uterine fibroids and endometriosis.
The Centre for Addiction and Mental Health has released comprehensive reviews of the most effective treatments for alcohol dependence, emphasizing medication and psychosocial therapies. These interventions have been shown to be effective in treating problem alcohol use and concurrent disorders.
A new study published in the Journal of American Medical Association suggests that reducing refined carbohydrates may help maintain weight loss better than reducing fat. Diets with low glycemic index or very-low carbohydrate consumption showed similar metabolic benefits to low-fat diets without negative effects on stress and inflammation.
A study found that a simpler lifestyle with fresh foods and limited use of environmental chemicals can reduce exposure to EDCs. Researchers analyzed urine samples from OOM women and compared them to NHANES data, finding lower levels of BPA and phthalates in the former group.
Researchers found panguite, a titanium oxide mineral, in the Allende meteorite, which is considered one of the best-studied meteorites in history. The discovery sheds new light on the formation and evolution of the solar system.
Researchers used magnets to guide iron oxide nanoparticles-laden cells to damaged heart sites, improving homing and retention. Visualizations revealed a good correlation between MRI tracking and cell fate assessment.
A new study by U-M researchers found that residency programs vary in their interpretation of National Residency Matching Program rules, leading to stress for both OB-GYN residents and program directors. The study suggests that frequent communication with candidates may create an unfair advantage, undermining the original purpose of the...
A study published in Psychological Science found that reminding people of their mortality motivates them to behave in ways that ensure their personal legacy, leaving a positive impact on the environment. Participants who were primed with thoughts of death gave more money to charities serving impoverished communities in the future.
A study at the University of Chicago shows that offering immediate rewards for good scores can dramatically improve test performance, particularly for low-performing students. Researchers found that non-financial rewards, such as trophies, were more effective for younger students than financial rewards.
Researchers at Berkeley Lab develop 3D optical cavities with potential to generate intense nanolaser beams, suitable for various technologies including LEDs and optical sensing. The unique electromagnetic properties of these cavities enable new approaches for designing nano-scale optical cavities.
A new study suggests that viewing images of high-calorie foods stimulates the brain's appetite control center, leading to increased desire for food. The research found that this stimulation may contribute to overeating and obesity, particularly in high-risk populations such as Hispanic young women.
A study of 1.2 million veterans found that the federal government spent an estimated $13 billion in six years on duplicate Medicare Advantage payments for care provided by both the VA and private health facilities. The study suggests policymakers consider measures to identify and eliminate redundant expenditures.
Moderate coffee consumption as part of a daily routine may be linked with a significantly lower risk of heart failure. The study found that moderate coffee drinking reduces the risk by as much as 11 percent, while excessive consumption has no benefit and may even be dangerous.
A Michigan State University study found that online shoppers tend to be happier when they receive an offer rather than making one. This can have significant impacts on the fast-growing e-commerce industry. By putting customers in the receiver role, businesses may be able to fill more hotel rooms and airplane seats.
The EVINCI study found that non-invasive imaging tests, such as multi-slice CT and radionuclide imaging, can accurately diagnose coronary artery disease in most patients. This approach could safely avoid invasive procedures in 75% of cases, reducing unnecessary treatments.
New research highlights the impact of atmospheric gravity waves caused by thunderstorms on air safety, leading to a call for rewritten guidelines. The study reveals that thunderstorms can produce unexpected turbulence more than 100km away from storm cells, posing risks to passengers.
A study by UCSF found that bacterial vaginosis increases female-to-male HIV transmission risk threefold. Women with the condition are more likely to transmit HIV to their male partners, highlighting the need for better understanding and treatment of the disorder.
Researchers have created an ultrafast nickel-iron battery that can be fully charged in about 2 minutes and discharged in less than 30 seconds. The new battery uses graphene and multi-walled carbon nanotubes to improve performance, making it suitable for applications such as electric vehicles and emergency situations.
A new study found that the federal government made $13 billion in duplicative payments to provide health-care services to veterans enrolled in Medicare Advantage plans. The researchers analyzed over 1 million veteran records and found that 61% used both VA and Medicare Advantage coverage.
The study found that large proportions of young people across racial and ethnic groups have access to the Internet and use online social media regularly. Participatory politics are an important dimension of politics, with 41% of young people engaging in at least one act during the prior 12 months.
A study of three diets found that a low-fat diet led to the greatest decrease in resting energy expenditure and total energy expenditure following weight loss. The researchers suggest that a low-fat diet may increase the risk for weight regain compared to other diets.
Researchers in Japan have concluded that adult-derived induced pluripotent stem (iPS) cells and mouse embryonic stem (ES) cells demonstrate similar survival and neural differentiation capabilities when transplanted into mouse cochleae. However, iPS cell transplantation is associated with a risk of tumor growth, highlighting the importa...
A new study published in American Politics Research suggests that attack ads sponsored by independent groups are more persuasive and less likely to trigger backlash. The research found that voters punish politicians for sponsoring negative ads, but do not hold the independent groups accountable for their content.
A new analysis of surface textures reveals that microscale roughening can improve heat transfer by more than doubling the maximum dissipation. The research found that a simple roughening of the surface improved heat transfer as much as previous techniques used to produce nanoscale patterns, and provides a theoretical framework for anal...