Researchers found a new genetic mechanism that bacteria use to cause shigellosis, increasing its virulence. This discovery could lead to the development of targeted treatments for this deadly disease.
Research reveals Arctic plants are adapting to rising temperatures by growing taller and expanding, particularly evergreen shrubs, with vascular species like shrubs and plants becoming more widespread
Researchers have imaged the structure of the S-layer protein coat in bacteria down to individual atoms, revealing its role as a protective layer. The discovery provides insights into how bacteria interact with their environment and could lead to new nanomaterials and drug delivery methods.
A study by the Society of Nuclear Medicine found that most patients with differentiated thyroid cancer have excellent survival rates, similar to those without the disease. The majority of patients with early-stage thyroid cancer can live a long and healthy life, thanks to advancements in diagnostic and therapeutic strategies.
Researchers at UCLA discovered that purified human perivascular stem cells can form bone faster and with higher quality than traditional methods, potentially eliminating the need for invasive bone grafts. The study uses a fresh cell composition called stromal vascular fraction to isolate and purify the stem cells.
A study of 700 people living with HIV in Russia found that approximately half reported not disclosing their status to all partners. The findings suggest that risky alcohol use is common, but does not contribute to nondisclosure, emphasizing the importance of counseling and encouraging disclosure to prevent further HIV spread
Researchers at the University of Gothenburg are working on developing substances that can prevent parasites, bacteria, and fungi from producing essential proteins. If successful, this could lead to the development of new drugs for several major diseases, including cancer, parasitic diseases, and bacterial and fungal infections.
A joint research project between Aarhus University and the Danish Cancer Society shows that mindfulness-based psychological therapy helps reduce anxiety and depression in cancer patients. Mindfulness teaches patients to be more conscious of life as it happens, reducing negative thoughts and worries.
Researchers at UNC Health Care identify a key genetic switch that determines melanoma's ability to spread. Inactivating the LKB1 gene causes non-aggressive cells to become highly metastatic.
A new Northwestern University study suggests that children of older fathers inherit longer telomeres, which may promote slower aging and facilitate extension of lifespan. The association is cumulative across multiple generations, offering insights into the evolution of aging.
A new study found that gay and lesbian couples are more likely to engage in mutual health behaviors, while straight couples rely on one partner as the 'health expert.' The research also suggests that societal conditions can shape health behavior dynamics in intimate partnerships.
In a pilot study, patients with type 2 diabetes who used Almased, a protein-rich meal replacement, lost weight and gained better blood sugar control. After 12 weeks, average insulin doses decreased from 147 to 65 units per day and HbA1c levels dropped by 7.7%.
A new study found that people with mild cognitive impairment were nine times more likely to be slow walkers than moderate or fast walkers. The study used a new technique to detect changes in walking speed and found that fluctuations in walking speed were also associated with MCI.
Researchers have created a massive database of Mars' impact craters, containing 635,000 craters over 1km in diameter. This will aid in dating Mars' regions and understanding water volcanism and potential past habitability.
A Stanford researcher discovered that certain human embryonic stem cells produce molecules that benefit themselves and nearby cells during stress, exhibiting 'altruistic' behavior. This unique trait is linked to an increase in p53 protein fluctuations, enabling some stem cells to maintain their stemness and secrete antioxidant glutathi...
Research found no increase in infective endocarditis among dental patients following updated guidelines, which restrict antibiotic use to those at greatest risk of complications. The study's results are reassuring but suggest further research is needed to support the findings.
Researchers have made significant breakthroughs in Alzheimer's disease detection using molecular imaging technology, which can identify beta-amyloid plaques in the brain. Studies show that high levels of amyloid binding are associated with an 80% chance of developing Alzheimer's disease within two years.
A new rapid-cooling process can extend egg shelf life by up to 12 weeks, maintaining protein quality and preventing bacterial invasion. The technology uses liquid carbon dioxide to cool eggs quickly, reducing the risk of salmonella illnesses.
Researchers develop unique technology that keeps devices working in the presence of ionizing radiation, suitable for space applications and control systems, and overcome current radiation-resistant technologies' drawbacks. The new logic gates perform logical operations and can be used to build circuits such as adders and multiplexers.
Researchers have identified a pair of proteins, RGS7 and RGS11, that play an essential role in vision, particularly in dim light environments. The study reveals that these proteins help regulate cells' response to light, enabling the transmission of visual information to the brain.
The University of Bristol scientists developed a technique to calibrate six Amazon gauges using ICESat elevation data, correcting large discrepancies in water levels. This method enables researchers to accurately estimate water levels and river slope, crucial for understanding the exchange of water with floodplains and other processes.
Researchers used bioluminescence imaging to track hair follicle stem cells in mice, showing successful regeneration of new hair follicles. The study paves the way for future clinical trials to test the efficacy of this novel therapy for human hair regeneration.
A population of cells in the squamo-columnar junction of the cervix have been found to be responsible for most HPV-associated cervical cancers. These cells can become cancerous when infected with HPV, while other cells in the cervix appear to be resistant to infection.
New research from the University of Copenhagen found that even slightly higher blood glucose levels increase the risk of ischemic heart disease. A study of over 80,000 participants revealed a 69% increase in risk with just 1 mmol above normal levels.
A new study by Miriam Liss and Mindy Erchull found that feminist mothers support time-intensive, hands-on parenting practices associated with attachment parenting. The researchers surveyed 431 American women and found that feminists were more likely to endorse attachment parenting than non-feminists.
A study by Joslin Diabetes Center found that a significant number of people with long-term type 1 diabetes developed little to no diabetic eye disease over time. The researchers hope to identify the factors behind this protection, which could lead to new treatments or prevention strategies.
A new computer model has successfully predicted negative side effects in hundreds of current drugs by analyzing their chemical structures and known side-effect molecules. The model identified potential side effects for 151 previously unknown compounds, including a synthetic form of estrogen that causes stomach pain.
A new study by Rice University and Long Island University found that corporate political activity is negatively associated with market performance. Firms' political investments also worsen both market and accounting performance.
The American Academy of Neurology has issued an updated guideline outlining the best treatments for infantile spasms. The hormone therapy adrenocorticotropic hormone (ACTH) may be effective for treatment, with low-dose ACTH showing similar effectiveness to high-dose and potentially lower risk of side effects.
A recent study found that 26.7% of homeless adults in downtown LA are infected with hepatitis C, while nearly half (46.1%) are unaware of their infection status. The study also highlights the need for interventions such as HCV education, counseling, and voluntary testing and treatment services.
The prevalence of Type 1 diabetes among young people in the US has increased by 23% between 2001 and 2009, according to a new study. Researchers funded by organizations like JDRF are making progress in treatments, technology, and vaccines, but more support is needed to combat this life-threatening disease.
A study suggests that women can reduce their breast cancer risk by avoiding unnecessary medical imaging. According to the UCSF analysis of IOM report, radiation exposure from medical imaging is a known risk factor for breast cancer.
A new treatment protocol for kidney cancer uses molecular imaging and radioimmunotherapy to target clear cell renal carcinoma. The study found that the effectiveness of this therapy may be diminished when used after another anti-cancer drug, sorafenib.
A study of 5,666 people found that those sleeping less than 6 hours a night had a higher incidence of stroke symptoms among middle-aged to older adults. The researchers suggest that short sleep duration may be a precursor to other traditional stroke risk factors.
Researchers found that normalizing blood glucose levels in pre-diabetes patients can significantly reduce the risk of developing Type 2 diabetes. A study published in The Lancet revealed a 56% reduction in progression to diabetes among participants who achieved normal glucose regulation, regardless of its duration.
Researchers found that individuals with HIV who can control viral replication have killer T cells with effective T cell receptors, which recognize and kill infected cells. The study suggests that the particular sequence of the protein affects the ability to control infection.
Brown University engineers create a biochip called SMART that can detect influenza by identifying specific RNA sequences and separating them from other biological debris. The device is small, low-cost, and fast, making it potentially useful in first-aid kits.
A team of researchers has identified a hereditary enzyme deficiency, MPS IIIE, which leads to cognitive decline and learning difficulties in mice. The discovery also sheds light on the role of heparan sulfate degradation in lysosomal storage disorders.
A new treatment method using computers to address childhood anxiety disorders has shown promising results. The Attention Bias Modification (ABM) program, which uses a technique to reduce anxiety by changing thought patterns, was found to be as effective as medication and cognitive therapy for children.
A study found that First Nations children and those from families receiving government subsidies had significantly more visits to emergency departments for mental health crises. These visits were often due to anxiety- or stress-related disorders, emotional or behavioural issues from substance abuse, or unspecific diagnoses.
A new PET imaging technique using an amino acid probe can predict the effectiveness of brain cancer treatment as early as two weeks after initiation, without requiring invasive biopsies. This method provides vital information about the body's response to therapy and has shown promising results in patients with aggressive glioma tumors.
Research by Trinity College Dublin scientists establishes a clear link between nanoparticles and autoimmune diseases like rheumatoid arthritis. Exposure to nanoparticles can trigger the transformation of amino acids, leading to inflammation and tissue damage.
New research reveals the molecular basis of a bacterial effector protein called Cif, which manipulates host cell processes for infection and colonisation. The study identifies the structure of Cif bound to its target NEDD8, providing insights into pathogenesis and potential new tools for probing cellular functions.
Researchers in Japan have successfully generated a new liver system using hepatocyte cell transplantation. The study demonstrated the feasibility of propagating mouse hepatocytes by creating a vascularized platform and uniform hepatocyte sheets, leading to the functionality of the engineered liver system.
A new line of radioisotope therapy, Radium-223 chloride, has been shown to extend the lives of prostate cancer patients with advanced tumors that have spread to bone. The treatment has a short range of penetration and is usually well-tolerated, with serious side effects being rare.
Researchers develop new approach to designing antibiotics that target bacterial ribosomes without damaging hair cells, addressing ototoxicity. Apramycin shows promise against drug-resistant TB and other 'superbugs' without causing hearing loss.
A preclinical study found that normal p53, a tumor suppressor gene, makes breast cancer chemotherapy with doxorubicin less effective. Senescent cells produced by non-mutated p53 fueled the relapse of tumors. The research challenges the existing paradigm and is another step closer to personalized cancer medicine.
Research by Brown University ecologists finds that recreational fishing causes a trophic cascade, leading to the collapse of salt marshes along Cape Cod. The absence of top predators allows Sesarma crabs to overgraze, causing ecosystem decline.
Research finds that combining molecular imaging with computed tomography (CT) can reduce patient radiation dose. By using just one CT scan for multiple PET studies, researchers lower radiation exposure and improve image quality.
A team of researchers identified a unique set of cells at the squamocolumnar junction that express biomarkers found in all forms of invasive cervical cancers linked to HPV. These cells do not regenerate when excised, which has significant implications for diagnosis, prevention, and treatment of cervical cancer.
A new MIT study examines how chronic inflammation can lead to cancer. The researchers found that the liver and colon respond differently to infection, with neutrophils secreting hypochlorous acid damaging proteins and DNA in the colon. The study could help predict the risk of chronic inflammation and develop ways to halt it.
A new econometrics study shows that bank robberies yield modest proceeds, often lower than the cost of security devices. The average UK bank robbery generates £20,331, while US robberies yield $4,330. Firearms presence increases rewards, but also raises costs.
A study of 17 studies from seven countries found that smoking increases relative mortality by 83% for current smokers and 34% for former smokers. Quitting smoking at an older age is associated with a reduced risk of death, even after a longer follow-up period.
A recent study found that people prioritize features like fuel efficiency and time-saving over reduced smoke emissions when considering new cookstoves. The researchers suggest that health education and social marketing approaches may not be effective in changing user behavior.
A team of researchers has developed a 'time bomb' nanocontainer that releases vasodilator content exclusively to diseased areas, increasing treatment efficacy and reducing side effects. This technology exploits the physical phenomenon of shear stress in stenosed arteries to deliver targeted therapy.
New studies find insufficient data to draw conclusions on whether same-sex parenting disadvantages children. A review and new study reveal differences in social and emotional well-being between young adults raised by women with same-sex relationships and those in nuclear families.
Researchers have developed a simple blood test that can identify patients who will not respond to the painkiller tramadol. The test measures the ratio of tramadol's metabolite O-demethyltramadol (ODT) to tramadol itself, allowing doctors to switch non-responding patients to alternative painkillers like morphine.
Researchers at Oregon State University used data from underwater hydrophones and seismic analysis to detect an abrupt spike in energy about 2.6 hours before the eruption, suggesting a new method for predicting undersea volcanic activity. The study also revealed insights into the link between magma intrusion and seafloor deformation.
Researchers found that pre-operative aspirin therapy can halve the risk of post-operative acute kidney failure. The study involved 3,219 patients and showed a significant decrease in incidence of acute renal failure with aspirin use.
A 25-year study in Northern Sweden found that a switch to low-carbohydrate diets after reducing fat intake led to an increase in cholesterol levels, indicating a higher cardiovascular risk. Despite initial success in reducing cholesterol levels through dietary changes, the population's BMI continued to rise over time.