Researchers identified patterns in protein expression and found nearly 700 protein pairs implicated in networks of acute myeloid leukemia (AML) patients. The goal is to tailor therapy by targeting specific protein signaling pathways, which may lead to improved treatment outcomes.
Researchers discovered fluids flow through solid rock at a much faster rate than previously thought, with pulses occurring in a relatively short time along defined paths. This challenges current understanding of the formation of volcanic arcs and their connection to earthquake events.
Researchers have designed specialized proteins that assemble to form tiny molecular cages, which may be used for drug delivery or as artificial vaccines. The cages are hundreds of times smaller than a single cell and can be decorated with virus-identifying proteins to stimulate an immune response.
A low-carbohydrate high-protein diet has been found to be safe for healthy obese patients' kidney function and fluid balance, unlike a low-fat diet. However, additional studies are needed to evaluate its effects in individuals with pre-existing kidney disease or other health conditions.
A meta-analysis of 23 peer-reviewed studies found that working memory training programs have no impact on general cognitive performance or verbal skills. The study suggests that training may help with short-term memory related tasks but has limited effect on individuals with ADHD or other issues.
Researchers at Oregon State University have developed an AI-powered system to monitor bird sounds, identifying species and changes in habitat loss or climate change. The technology uses a multi-instance machine learning approach, allowing for efficient ecological monitoring, and can be applied to other forest noises and animal species.
An Emory University analysis suggests environmental factors trigger the monarchs' choice of winter homes, rather than genetic differences. The researchers found extensive gene flow between eastern and western monarchs, challenging the prevailing theory of distinct populations.
A new type of biosensor, known as a biochemiresistor, has been developed by a UNSW-led team to detect tiny traces of contaminants in liquids in just 40 minutes. The sensor can detect one-billionth of a gram of the veterinary antibiotic enrofloxacin in milk with high sensitivity and speed.
A major new study found that small marine snails have a profound impact on the marine ecosystem, removing almost 70% of plant material from the sea floor. The research, led by Associate Professor Alistair Poore, reveals that snails are a key driver of herbivory in marine habitats.
A new study funded by the California Raisin Marketing Board found that eating raisins as an after-school snack prevents excessive calorie intake and increases feelings of fullness. The three-month study among normal-weight children ages 8-11 showed significant benefits from snacking on raisins.
A novel compound has shown significant benefits in patients with KRAS-mutant non-small cell lung cancer, improving treatment response and survival times. The study's findings suggest a potential effective treatment for this common subtype of lung cancer.
The new study proposes a way to effectively introduce carefully planned DNA segments into genomes of living cells and test the effects. The technology enables simultaneous introduction of tens of thousands of DNA regions into tens of thousands of living cells, allowing for precise measurement of results within a single experiment.
Research at UCSF links smoking during pregnancy to increased risk of acute asthma symptoms in teens. The study found a significant association between maternal smoking and asthma severity in African-American and Latino children.
A new study found that liberals and conservatives tend to donate more to charities aligned with their respective moral foundations. Republicans are more likely to donate when a charity supports traditional values and loyalty, while Democrats are more inclined to donate when the emphasis is on equality and protection from harm.
Scientists at Aarhus University have developed a new technology that conjugates glucocorticoid steroids to antibodies binding to macrophage receptors, reducing side effects and increasing potency. This intelligent medicine shows promise for treating various inflammatory diseases, including autoimmune disorders.
Scientists have determined the three-dimensional structure of CLOCK and BMAL1 proteins, which regulate gene expression in response to daily cycles. The discovery provides new understanding into the intricacies of biological clocks and may lead to breakthroughs in treating circadian-related disorders.
A new study found that relatively few black and white families are moving into multi-ethnic neighborhoods, with many instead staying in homogenous communities. The study analyzed mobility patterns of over 44,000 black and 57,000 white families between 1977 and 2005.
A University of Tennessee professor has helped reveal a rare orbital shift and the density of an asteroid that will pass close to Earth. The asteroid, 1999 RQ36, has a low density and its orbit has drifted roughly 100 miles in the last 12 years due to the Yarkovsky effect.
Researchers found that a mutation in the BTBD9 gene in fruit flies disturbs sleep patterns, similar to restless legs syndrome (RLS) in humans. The mutant flies have altered dopamine levels and are more mobile during wakefulness.
A study published in the Journal of Applied Physiology found that runners can improve their performance and health by reducing their training time to 20-30 minutes per session. The research involved 18 moderately trained runners who followed the 10-20-30 training concept, which consists of 5-minute running intervals with rest periods.
The elderly are at higher risk for property crimes, self-neglect, and abuse, with financial swindles being one of the fastest-growing forms of abuse. Studies have shown that older homicide victims are more likely to be female and killed by family members or in the course of a robbery.
Researchers at Howard Hughes Medical Institute solved the first structure of a Wnt protein, offering insights into its function and therapeutic potential. The breakthrough provides a new era for understanding the role of Wnt proteins in biology and disease, including their potential as cancer therapies.
Researchers at U of A used 3-D magnetic resonance to map the structure of Candida, a deadly pathogen with a 40% mortality rate. This breakthrough could pave the way for an effective vaccine development.
A new study finds that preserving forests can curb climate change more effectively than harvesting wood as fuel. The research suggests that managing forests for maximal carbon storage can yield significant, predictable benefits within the coming century.
A new mathematical model created by Stanford psychologists can predict pragmatic reasoning and may lead to more human-like computer systems. The model helps computers better understand inference, context, and social rules, potentially improving customer service interactions.
Researchers have identified a genetic variant in a cardiac protein that increases the risk of heart rhythm dysfunction and sudden death in patients with dilated cardiomyopathy. The variant, known as Ser96Ala, affects calcium regulation in heart cells, leading to arrhythmias and increased mortality.
The increasing misuse of prescription opioids has led to a four-fold rise in individual use since the mid-1990s, resulting in nearly three-quarters of fatal drug overdoses being due to prescription drugs. Experts recommend expanded prescription drug monitoring programs to identify potential abusers and protect pain patients.
Women who exercise regularly and eat a diet rich in fruits and vegetables have a significantly longer life expectancy than those who don't. The study found that the most physically active and fruit/vegetable-consumption groups were eight times more likely to survive a five-year period, with death rates being up to 71% lower.
A follow-up NIH study confirms that hypothermia treatment increases infant survival, without increasing long-term disability risk. Children who received the cooling technique were more likely to survive to ages 6 and 7 compared to those who received routine care.
A large international consortium has successfully sequenced the tomato genome for the first time, revealing its genetic code and potential applications in improving crop yields, flavor, and aroma. The achievement is expected to have significant implications for food production and culinary innovation.
Research reveals voluntary organizations can successfully change behavior in local settings through collective action and alternative infrastructures. However, scaling up these initiatives to reach the wider public is a challenge, requiring additional government support.
Researchers developed a 'Top 20' list of questions to better understand the impacts of chemicals in PPCPs on human and ecological health. The top priorities include identification of PPCPs, understanding their entry into the environment, and assessment of effects on organisms and risks to people.
A recent study published in the Journal of General Internal Medicine found that nearly a quarter of adults at risk of overdosing on single OTC acetaminophen products by exceeding the dose of four grams in a 24-hour period. Additionally, nearly half were at risk of overdosing by 'double-dipping' with two acetaminophen-containing products.
A team of researchers at UCSC has developed a photoactive compound that releases nitric oxide when exposed to light, eradicating highly resistant 'Iraqibacter' bacteria. The treatment was tested in laboratory models and showed promising results.
The guidelines aim to improve diagnosis and treatment of childhood aggression, avoiding inappropriate medication use. They recommend a team-based approach, using proven psychological therapies before prescribing antipsychotic or mood stabilizer medications.
Researchers at the University of Pittsburgh School of Medicine have identified an agent called E4 that can protect the skin and lungs from fibrosis, a process that can lead to organ failure and death. The agent may work by stalling the cross-linking of collagen needed to form thick scars.
The Esther B. O'Keeffe Charitable Foundation has donated $2 million to the Scripps Research Institute to support biomedical research and education. The gift will fund special initiatives on the Florida campus, including state-of-the-art scientific infrastructure and graduate student programs.
Scientists have discovered that the moon's presence affects the solar wind, creating turbulence and changes in direction and density. Computer simulations explain this phenomenon by showing an electric field near the lunar surface generated by sunlight and solar wind flow.
Researchers develop new antibodies that bind to MUC1 protein on cancer cells, depositing toxins directly into diseased cells. This method has shown higher efficacy than existing treatments and may be available for more cancer varieties in the future.
New research from Johns Hopkins Medicine reveals that patients with a past history of skin infection are three times more likely to develop painful and costly surgical site infections during operations. Despite following proper procedures to prevent SSIs, some patients appear to be more susceptible to contracting an infection due to un...
Researchers have identified dozens of zeolite minerals that can improve the energy efficiency of carbon capture technology, reducing 'parasitic energy' costs by up to 30%. The new materials could significantly enhance the feasibility of capturing CO2 from power plant emissions and storing it underground.
A new study suggests that genetic variations can predict a person's response to drug treatments for nicotine addiction, with those at high-risk of heavy smoking showing the greatest response to pharmacologic therapy.
A study published in PLOS ONE found that office bacteria are most abundant on chairs, phones, and human skin, with over 500 bacterial genera identified. The study also revealed that men's offices have significantly more bacteria than women's, but the diversity of communities didn't show significant differences.
Researchers at the Wyss Institute have developed a method for building complex nanostructures out of short synthetic strands of DNA. This technology, called single-stranded tiles, can assemble themselves into precisely designed shapes and may enable the creation of new nanoscale devices for targeted drug delivery.
A recent study by Dr. Paul DeLaune found that reduced tillage has no impact on cotton yields and can even increase net returns through deficit irrigation. The research suggests that conservation tillage systems can conserve water resources and reduce energy usage, making them a viable option for cotton producers in semiarid environments.
Research finds that belief in God is associated with better theory of mind, a cognitive ability to understand others' thoughts and feelings. The study also explores the gender gap in religious belief, suggesting that women tend to be more religious than men due to differences in mentalizing abilities.
A growing concern overdiagnosis is harming the healthy, with evidence mounting that it's occurring for a wide range of conditions. Overdiagnosis occurs when people are diagnosed and treated for conditions that will never cause them harm.
A study led by Indiana University professor Nicole Martins found that TV exposure decreases self-esteem in black girls and boys, while improving it for white boys. The study suggests that media portrayal plays a significant role in this disparity.
Dr. Patricia Dickson's research aims to develop a stem cell-based therapy for mucopolysaccharidosis I, a fatal pediatric disease causing neurodegeneration. The project seeks to address critical issues in the development of therapeutic candidates.
Researchers at the University of Alberta found that omega-3 fatty acid DHA in fish prevented toxic buildup in the retina, a common cause of age-related vision loss. The discovery could lead to a therapeutic use for supplementing the diet with DHA.
A Concordia research team, led by Pragasen Pillay, is working on a two-year project to reduce the need for permanent magnets in electric vehicle motors. They aim to cut costs and improve performance using existing manufacturing facilities.
New eyewitness identification procedures being adopted by police departments across the US may lead to fewer correct identifications while reducing false errors. Researchers raise concerns that these changes could have unintended consequences and policymakers need to carefully weigh the data before making policy decisions.
A recent study published in International Review of Financial Analysis warns fine wine investors not to put all their eggs in one basket by focusing on French wines. Diversification across Italian, Australian, and Portuguese wines could prove a shrewd move for investors looking to minimize risk.
Researchers found that married people tend to be happier than single individuals, as marriage stabilizes happiness levels despite life changes. Personality traits do not play a significant role in adapting to major events like marriage or job loss.
Researchers at UC Santa Barbara developed synthetic platelets with unique physical and biochemical properties to mimic natural platelets. These particles could be used for various biomedical applications, including wound healing, targeting damaged blood vessels, or delivering drugs that dissolve blood clots.
A new study found that companion presence in physician visits hinders communication for older adults with poor mental health, leading to shorter visits and less patient-centered care. The research suggests a need for greater attention to primary care infrastructure to support delivery of mental health care.
A study led by Dr. Manel Esteller has completed the first epigenome in Europe, shedding light on the activity of genes and tissues in complex diseases like cancer. The research found that a patient with a rare genetic disease had an epigenomic defect causing fragility of chromosomes and immune deficiency.
A new NIST report summarizes efforts to advance indoor microbial sampling, highlighting challenges and future priorities for surface and aerosol analysis. The report explores cross-cutting issues such as education and public awareness, and provides a comprehensive overview of existing resources.
A recent report synthesizes published studies on the impact of bark beetles on wildfires, revealing that tree mortality can indeed affect fuels and fire behavior. However, the extent of these effects depends on various factors, including the time since the outbreak and the type of fuel or fire characteristic being studied.
A retrospective analysis found that methotrexate injection was not more effective than oral therapy in treating juvenile idiopathic arthritis. The study suggests that the oral approach may be a more suitable option for pediatric patients, sparing them from the pain of injections.