Researchers identified 20 distinct mutations in a specific gene causing Familial Glucocorticoid Deficiency (FGD), leading to cortisol production issues. The antioxidant gene NNT provides a new mechanism for this adrenal disease, potentially opening doors to treating other diseases.
A UK research team is using a novel 'back-casting' approach to transform cities for healthier lives by creating visions of alternative urban futures with drastically reduced CO2 emissions. The study will develop realistic and radical engineering solutions to achieve these goals while ensuring social acceptance.
A new study finds that children exposed to high levels of naphthalene are at increased risk for chromosomal aberrations, including translocations. The researchers discovered a link between naphthalene exposure and an increased likelihood of chromosomal aberrations in children.
Researchers have identified a new HIV-suppressing protein called CXCL4, which binds to the outer coat of the virus and prevents it from entering human cells. This discovery may provide new insights into treating and preventing HIV disease progression.
Researchers developed a program to screen and treat pregnant women for mental health disorders, achieving high uptake and acceptability rates. The model demonstrates the feasibility of stepped care approaches for primary healthcare settings.
Researchers from University of Copenhagen analyzed 80-year-old aerial photos to study glacial evolution in Greenland. The results show that glaciers can recover within a short timeframe if temperatures decrease, contradicting current global warming models.
A Stanford study found that an antioxidant supplement, N-Acetylcysteine (NAC), lowered irritability in children with autism and reduced repetitive behaviors. The researchers believe NAC could be a valuable tool to treat certain features of autism, but further trials are needed.
A novel technique using stable hydrogen isotopes enabled researchers to determine the summer origins of tens of thousands of bats hibernating in three Michigan mines. This could help predict and manage the spread of white-nose syndrome by identifying connected hibernation sites.
Researchers have successfully developed a genetically modified microorganism that produces high levels of arachidonic acid, a key fatty acid essential for infant nutrition. The microorganism, produced through ion beam mutation breeding, has shown promise for industrial application and potential use as a sustainable bio-diesel source.
A 16th-century Korean child's mummified liver has revealed a unique hepatitis B virus (HBV) genotype C2 sequence common in Southeast Asia, providing insight into the virus's evolution and spread. The ancient genome is the oldest full viral genome described in scientific literature.
A systematic review found that trafficked women experience high levels of physical and sexual violence, as well as anxiety, depression, and post-traumatic stress disorder. The study also highlights the lack of evidence on the health consequences experienced by trafficked children, men, and individuals trafficked for labor exploitation.
Researchers developed STeleR, a home telerehabilitation program that improves lower body physical functioning after a stroke. Participating in STeleR also enhances money management skills and improves daily living abilities.
A whole-genome sequencing study found that HBV integration is a common event in liver tumors, associated with tumor size, serum HBsAg levels, and α-fetoprotein. The study identified three novel genes linked to recurrent HBV integrations, which may lead to targeted therapies for liver cancer.
Tropical Storm Beryl formed off the Carolina coast and was monitored by NASA satellites. The storm made landfall near Jacksonville, Florida, causing heavy rainfall and dangerous surf conditions in nearby areas.
Researchers at Indiana University have conducted two studies on bisexual individuals, finding that women who identify as bisexual or lesbian report better health when their sexual identity matches their recent sexual history. In contrast, queer-identified women's mental, physical, and sexual well-being is not related to the gender of t...
Researchers at the University of Texas at Austin have uncovered the mechanism behind V. cholerae's resistance to human immune responses. The discovery could lead to the development of a new class of antibiotics that target the bacteria's defenses, rather than directly killing them.
The Illinois livestock industry contributes significantly to the state's economy, generating over 25,000 jobs and $3.5 billion in production. The report also highlights the importance of strategic partnerships between the livestock industry and meat and dairy processing sectors.
Studies found that stun gun use increases citizen injuries by 41% when solo and 47% when paired with other force methods, but officer safety is also heightened
Research reveals Greenland's ice sheet is losing mass at an unprecedented rate, with melting and calving processes increasing by 0.07mm/year annually since 2005. The study provides insights into the impact of regional weather patterns on ice sheet dynamics.
Researchers from South Korea, Sweden, and the US have successfully transplanted HD-induced pluripotent stem cells into animal models, exhibiting significant behavioral recovery. The study provides new insights into the underlying disease process and potential treatments for Huntington's disease.
Research on LRRK2 protein mutation G2019S reveals potential drawbacks of blocking its kinase activity. In a study published in Molecular Neurodegeneration, deleting the kinase domain of LRRK2 led to changes in motor coordination and anxiety-like behaviors in mice without affecting dopamine signaling.
Researchers analyzed 80-year-old photo plates and found that glaciers were melting faster today than in the 1930s, with most glaciers retreating at an average of 20 meters per year. A brief cooling period in the mid-20th century allowed new ice to form before accelerating again.
The Mass. Eye and Ear Cataract Master uses computer-based simulation to provide a realistic interactive experience for ophthalmology residents and practicing surgeons. The program aims to minimize clinical risk while boosting skills and confidence, ultimately raising the quality of patient care.
A £425,000 study at Queen's University Belfast aims to discover how the immune system supports tissue repair in Multiple Sclerosis (MS). The research seeks to understand how ageing affects this process and potentially lead to new treatments for MS.
The REMARK checklist provides criteria for assessing the completeness of reporting tumor marker studies, aiming to improve quality and relevance of research. Good reporting reveals study strengths and weaknesses, facilitating sound interpretation and application of results.
Researchers discovered that hawkmoths can detect minuscule differences in humidity near flowers to determine if they have enough nectar. This allows the moths to quickly evaluate flowers and avoid wasting energy on unprofitable ones.
University of Michigan Health System study shows that lean thinking techniques can improve efficiency, morale, and teamwork in the operating room. The study found significant improvements in turnaround time, staff empowerment, and problem-solving skills.
La Jolla Institute scientists discovered a mechanism key in drug allergy, identifying HLA gene-linked hypersensitivity reactions before use in humans. The finding could lead to pre-screening of drugs at risk of causing severe reactions.
Researchers have identified a biomarker for advanced bile duct fibrosis and bile duct cancer caused by the Asian Liver Fluke, allowing for earlier detection and potentially saving lives. The Thai Ministry of Health has implemented testing for this biomarker in endemic regions to identify individuals at risk.
A majority of California's coastal planners acknowledge the need to prepare for climate change impacts like rising sea levels and increased floods. Despite challenges such as limited funding and staff resources, many professionals are actively planning and trying to understand their climate change risks.
A study found that female fat prejudice persists even after weight loss, with participants viewing thin women with a weight loss history as less attractive. The researchers also discovered that negative attitudes towards obese people increase when participants are falsely told that body weight is easily controllable.
The Women's Health Initiative has revealed that hormones produce a mix of risks and benefits for postmenopausal women. The trial found that HT varies with age, being safer when started soon after menopause.
Researchers found that smoking contributes to higher hospital costs for surgical patients, with an estimated $900 added cost per patient. The study suggests the need for preoperative behavioral interventions targeting smoking cessation to improve surgical outcomes and reduce healthcare costs.
The tuatara's unique chewing technique, using its lower jaw to slice food apart, raises doubts about the link between chewing and high metabolism in mammals. This specialized mechanism allows the tuatara to eat a wide range of prey, including beetles, spiders, and small lizards.
Researchers found that two bloodletting sessions improved blood pressure, glucose levels, and cholesterol ratios in obese individuals with metabolic syndrome. Blood donation may prevent diabetes and cardiovascular disease in these patients.
Duke University chemists created copper-nickel nanowires with improved stability and conductivity compared to plain silver and copper. The new material is an attractive option for printed electronics applications, including solar cells, LEDs, and clothing. Its low cost and high speed make it suitable for mass production.
The study reveals that tafamidis works by stabilizing the transthyretin (TTR) protein tetramer, preventing it from aggregating into amyloids. This stabilization prevents nerve destruction in polyneuropathy patients and delays disease progression.
A study of over 11,000 university students found that adhering to the Mediterranean diet increased scores on quality of life questionnaires, particularly for physical well-being. The diet's emphasis on fruits, vegetables, whole grains, and healthy fats was associated with better mental health outcomes.
A growing number of recession-weary Americans are shifting towards 'gift economies' built on freebies and community spirit. Online gift-giving communities like Freecycle generate strong feelings of solidarity and identification, driving people to give more gifts in the system.
Researchers found that Exendin-4 significantly minimizes damage in TBI animal models when administered shortly after the incident. The breakthrough discovery is a step towards developing a cocktail of medications to prevent as much brain damage as possible following injury.
Typhoon Sanvu transformed into an extra-tropical storm due to cooler sea surface temperatures and wind shear, weakening it significantly. The storm passed Chichi Jima island on May 27, with most rainfall pushed to the northeast of its center.
Researchers at Linköping University have developed the first chemical circuit, combining ion transistors to control and transport ions and charged biomolecules. This breakthrough enables chemical control of muscles and signaling systems in the human body, with potential applications for treating diseases.
A team of international mathematicians has devised an amplifier that can boost light, sound, or other waves while hiding them inside an invisible container. The researchers propose using this technology to manipulate matter waves, which could enable the creation of a quantum microscope to monitor electronic processes on computer chips.
A study by Weizmann Institute scientists reveals that leukemia recurrence is often caused by 'cancer stem cells' that divide slowly, evading chemotherapy drugs. These cells can give rise to new rapidly-dividing cancer cells, making them a key target for new treatment approaches.
A new study found that World No Tobacco Day significantly increases interest in quitting smoking, with cessation news coverage and Internet search queries peaking on the anniversary day. The research also suggests that low- and middle-income countries can benefit from increased awareness and inspiration to quit tobacco.
The DFG is establishing 20 new Collaborative Research Centres to tackle ambitious, long-term projects. The centres aim to improve our understanding of stress responses, develop new therapies for multiple sclerosis, and increase efficiency in gas turbines.
The Singapore-developed H5N1 diagnostic kit can detect all known strains of the virus in a single test within hours. This allows for rapid diagnosis and effective infection control intervention.
A new study by a University of Illinois expert reveals that operational routines tend to move towards higher entropy due to complacency and lack of checks and balances. The research also found that mergers can cause decay in adherence to routines, while acquisitions by healthier firms can serve as a renewal.
The Navy awarded nearly $4.5 million to six research projects led by Scripps Institution of Oceanography researchers, including Eric Terrill, to acquire instruments from California and Massachusetts manufacturers. The funding will support studies in coastal oceanography, deep-ocean acoustics, and other areas.
Researchers discovered that cancer cells release exosomes containing pro-metastatic proteins that fuse with distant organs, establishing a nurturing environment for tumor growth. This discovery offers fresh diagnostic and treatment potential, including the use of exosomal protein profiles to predict tumor aggressiveness.
Researchers at Salk Institute create cell-free expression system to synthesize and analyze integral membrane proteins, solving their three-dimensional structures in just 18 months. This breakthrough enables precise biochemical mechanisms understanding and targets the proteins with new drugs.
A new study found that emissions from cookstoves are highly dependent on how they are used, and laboratory tests do not accurately reflect real-world operations. The research team developed a real-time analysis technique called Patterns of Real-Time Emissions Data (PaRTED) to measure emissions under different operating conditions.
A new series in PLoS Medicine aims to address the gap between public health approaches and clinical methods for addressing mental disorders. The series seeks case studies that demonstrate global mental health practices in real-world contexts.
A case study from Afghanistan reports a substantial increase in mental health consultations, from 659 to 20,000, after integrating psychosocial problems into basic health services. The authors argue that concurrent community-based approaches and capacity building are crucial for fostering structural changes within the healthcare system.
The University of Strathclyde in Glasgow will host the first Fraunhofer Centre to be established in the UK, a hub for industry-driven laser research and technology. The Centre is part of Fraunhofer UK Research Ltd., which will oversee future UK-based research centres.
Walter and Eliza Hall Institute researcher Professor Terry Speed was awarded the 2012 Thomson Reuters Citation Award in Biochemistry and Molecular Biology. His research has been cited more than other Australian researchers, with applications to infection, immunity, inherited diseases, and cancer.
A study of over 247,000 Copenhageners found higher mortality rates for both too little and too much vitamin D in the blood. The results challenge long-held assumptions about the essential nutrient's benefits.
The Lancet Commission on Healthy Cities highlights the need for active planning to address urban health issues, with examples from Mumbai, London, and Bogota. The report recommends five key recommendations to improve urban health, including building political alliances and experimenting with diverse urban health projects.
The St. Jude Children's Research Hospital has released the world's largest comprehensive human cancer genome data, exceeding volume of all other sources combined. This valuable information is available for free access by researchers, accelerating disease research and potentially leading to new treatment options for childhood cancers.
A study published in Public Health found that Scotland's higher mortality rates may be linked to the political direction of past decades, rather than single factors like smoking or poor diet. The researchers identified a range of potential explanations, including climate change and economic inequality.