A new study by Dr. Chaim Bell at St. Michael's Hospital has revealed huge variations in the charges ophthalmologists impose on specialty lenses used in cataract surgery. Most surgeons charge less than the maximum recommended rate, while others charge significantly more, potentially representing predatory pricing.
Researchers found that anti-depressants have negative health effects on developmental problems in infants, sexual stimulation and function, digestive issues, and abnormal bleeding in elderly patients. The benefits of most anti-depressants compare poorly to the risks, including premature death in elderly patients.
A new project led by University of Michigan math professor Daniel Forger aims to understand how the brain's daily clock controls mood in humans and animals. The study uses mathematical modeling and experiments involving mice to examine the relationship between abnormal circadian rhythms and bipolar disorder.
Scientists have developed a new imaging method that combines PET and CT scanning to identify patients at high risk of a heart attack. The technique, which targets active calcification in coronary arteries, shows promise in improving heart attack prediction and reducing mortality rates.
GW researchers are evaluating innovative methods to assess the immune response to vaccines with a novel Toll-like Receptor (TLR)-4 agonist adjuvant. They will use new antibody profiling techniques to determine the quality of the humoral immune response in humans.
Economists create new framework for examining developing economies by analyzing Thai villages. Preliminary findings show highly integrated capital markets across villages, with households relying on informal borrowing and gifts to finance opportunities.
Researchers at UCSD School of Medicine identified G protein-coupled receptors as potential biomarkers and therapeutic targets for chronic lymphocytic leukemia. The expression of specific GPCRs, such as VIPR1, is linked to disease stage and prognosis.
Community health plans have broken down silos of care to coordinate among providers and directly engage with patients, leading to successful transitions. The Avalere report highlights five practices that facilitate care transition programs, including using data to tailor programs to patients' needs.
Detailed studies reveal an unusual bilayer lamellar structure in a top-performing organic photovoltaic material. This structure may contribute to the material's superior performance, offering clues for guiding the synthesis of new materials.
The new Iowa River bridge features over 100 gauges that take 100 readings a second, providing quantitative information on the bridge's performance and condition. The system also monitors security and surveillance video, with data displayed in real-time on a website.
A team of scientists proposes that early four-legged creatures used dermal bones to neutralize acid buildup from breathing carbon dioxide on land. The bones, featuring complex ridges and furrows, may have helped these ancient animals buy more time on land by storing antacids.
Two studies found that severe fibrosis increases the risk of developing atherosclerosis at an earlier period. Fatty liver disease also increases risk, with GGT levels serving as a potential biomarker for early atherosclerosis.
A new study finds that bile plays a critical role in the development of Barrett's esophagus, a precursor to rare and deadly esophageal cancer. Bile shuts off genes responsible for normal esophageal lining and turns on genes producing intestine-like tissue.
A kinesiology research team at UMass Amherst will investigate how heavy loads affect soldiers' survivability, injury likelihood, and mission performance. The study, funded by the Navy Health Research Center, will also have practical implications for firefighters and law enforcement officers.
The Association for Research in Vision and Ophthalmology (ARVO) has announced its 2012 ARVO Award recipients, honoring vision researchers who have made significant contributions to the field of ophthalmology. This year's award winners include Peter Sterling, John V. Forrester, Jeffrey L. Goldberg, and Josh Wallman, who will be recogniz...
A new paper recommends cost-effective policies and programs to prevent behavior problems and conditions contributing to poor health. The initiatives have been tested in high-income countries and shown to reduce smoking, drinking, and other substance use among adolescents.
The editors of PLOS Medicine argue that disclosure policies for financial conflicts of interest in medicine may actually exacerbate the problem of bias. Studies in social science suggest that overemphasis on disclosure can leave the root issue unaddressed.
Researchers at Ames Laboratory have designed a method to evaluate different conductors for use in metamaterial structures. The team evaluated various conducting materials, including graphene and high-temperature superconductors, but found that silver and gold remain the best conductors for use in metamaterials.
Researchers at Michigan Technological University discovered that adding graphene to titanium dioxide increases conductivity, bringing 52.4% more current into the circuit in dye-sensitized solar cells.
Researchers found aged mice showed disrupted sleep behavior and weakened brain network activity in the suprachiasmatic nucleus (SCN), a brain area responsible for setting sleep-wake cycles. Individual SCN cells also exhibited more severe changes, suggesting a new understanding of aging's effects on the brain.
New research reveals that primary cilia on cells in the retina and liver can form long-lasting contacts with each other, indicating a new role for cilia in cell communication. This discovery suggests that cilia may play a key role in human genetic diseases related to ciliary dysfunction.
Researchers at Columbia University's Mailman School of Public Health found that text message reminders to parents increased the proportion of children and adolescents vaccinated against flu. The study, published in JAMA, showed a higher vaccination rate among those receiving text messages compared to traditional reminders.
The article discusses new research on dynamic earth processes, including the link between wildfires and sediment transport in coastal watersheds, as well as high-pressure metamorphism in northwest China. Additionally, studies on the Gold Hill shear zone and magma-filled fractures in the Appalachian mountain belt are also presented.
A study suggests that eating pistachios can increase beneficial bacteria in the gut, potentially supporting digestive health. Researchers found a stronger effect on gut microbiota composition in those who ate pistachios compared to almonds.
Researchers at Vetmeduni Vienna have shown that chronic myeloid leukaemia (CML) and B-cell acute lymphoid leukaemia (B-ALL) arise from the same long-term haematopoietic stem cells. Understanding this finding is crucial for developing targeted therapies, as current treatments may not effectively target cancer stem cells.
The study found that robot-assisted radical prostatectomy (RARP) resulted in superior outcomes compared to open radical prostatectomy (ORP), including reduced need for blood transfusions and complications during or after surgery. RARP patients were also less likely to have prolonged hospital stays.
A study found that CT exams increased among pediatric patients with non-traumatic abdominal pain in emergency departments from 1999 to 2007, while ultrasound use remained stable. This trend is concerning due to the potential risks of radiation exposure on children.
Researchers are investigating three popular wheat varieties to understand their drought tolerance mechanisms and how they can be improved. The study aims to identify key genetic regulators of drought tolerance, which is crucial for maintaining crop yields in dryland areas affected by drought.
A Stanford study suggests a potential treatment for stroke by increasing the generation of new nerve cells in the brain. The compound, LM22A-4, was administered three days after a stroke and showed faster recovery of athletic ability in mice. This approach may be a more accessible alternative to stem-cell therapy.
A new study links malaria resurgence to funding cuts, with 91% of episodes tied to weakened control programs. The research highlights the need for sustained financial support to maintain gains in malaria control.
Researchers at Linköping University have discovered that homing molecules can render toxic prions harmless, decreasing their toxicity and infectibility. This breakthrough could lead to the treatment of diseases such as Alzheimer's, which is caused by amyloid plaque with a similar but slower course.
The Biotechnology and Biological Sciences Research Council (BBSRC) is investing £4 million in nine new crop science projects to improve UK cereal crops, including oilseed rape, barley, and wheat. The projects aim to address bottlenecks in food production, reduce waste, and deliver cost savings.
Researchers found that antidepressant Zoloft accumulates in yeast cells, inducing autophagy and causing membrane distortions. This response supports the idea that depression may be linked to diminished BDNF secretions and suggests alternative targets for next-generation antidepressants.
A new validated method enables accurate analysis of flavanol stereochemistry in cocoa, providing crucial insights into its cardiovascular health impact. This breakthrough addresses important gaps in knowledge and has implications for future research and development.
A new study reveals that outpatient surgery patients are at risk for blood clots due to multiple factors such as age, surgery length, and type of procedure. The study suggests a need for better screening and prevention strategies in the growing outpatient surgery population.
The Lancet series highlights the major challenges facing adolescents today, including disparities in access to resources and services. Sexually transmitted infections with protracted courses are of particular concern, exacerbated by poverty and social inequalities in countries of all incomes.
The largest generation of adolescents worldwide faces significant health risks, including high rates of tobacco and alcohol use, obesity, and physical inactivity. The study highlights the need for better coordination across UN agencies and countries to produce regular reports on adolescent health.
Researchers at Linköping University have identified 20 molecular interactions in voltage sensors that lead to pore opening, shedding light on a key mechanism. The study's findings are crucial for developing new medicines targeting electrical excitability disorders.
A Rhode Island Hospital psychiatrist argues that lowering diagnostic threshold for bipolar disorder will lead to more false positives than true positives, resulting in inaccurate diagnoses and treatments. This could have severe consequences for patients, including increased use of unnecessary medications.
A study of nearly 20,000 cases of routine appendicitis at 289 hospitals and medical centers in California found significant discrepancies in hospital charges, ranging from $1,529 to $183,000. The median charge was $33,611, with county hospital charges being 37% lower than nonprofit hospital charges.
Researchers found that women's hearts showed no increase in blood flow during mental stress, unlike men, who experienced an increase. This difference could predispose women to heart problems under stress.
Researchers found that chronic cocaine users lost about 3.08 ml brain volume per year, almost twice the rate of healthy volunteers. The accelerated age-related decline was most prominent in the prefrontal and temporal cortex, important regions associated with attention, decision-making, and self-regulation as well as memory.
Researchers investigated omega-3 supplements' effects on cardiac diastolic function, finding no improvement in older adults. The study suggests that omega-3's benefits may fall on other aspects of cardiovascular function.
A family history of liver cancer is associated with a 70-fold increased risk of developing hepatocellular carcinoma, independent of hepatitis B or C markers. Monitoring individuals with family history and hepatitis markers may help identify HCC at an earlier stage.
A study by Long Island University researchers found that carvacrol, an oregano constituent, induces apoptosis in prostate cancer cells. This compound may represent a promising anti-cancer agent with reduced risk of severe side effects due to its common use as food seasoning.
Researchers from Durham University found that the probability of fractures extending beyond 0.6 kilometers is exceptionally low, with only one per cent risk beyond 350 meters. This analysis has implications for setting minimum distance requirements for fracking operations to prevent contamination of groundwater.
Research from NASA-funded scientists uses data from Cassini and Huygens spacecraft to estimate how long Titan's methane factory has been operating, with estimated ages ranging from 10 million to 1.6 billion years. The study provides new perspectives on the history of Titan's atmosphere.
A recent study published in the Journal of Women's Health found that a soy-based S-equol supplement reduced hot flash frequency by 3.09-3.66 daily and muscle/joint pain significantly compared to a standard soy isoflavone supplement. The study involved 102 US postmenopausal women who experienced high hot flash frequencies.
The Large Synoptic Survey Telescope (LSST) camera has received 'Critical Decision 1' approval, moving forward with detailed engineering design and construction. The LSST will capture the widest, fastest, and deepest view of the night sky, aiding studies of dark energy, near-Earth asteroids, and the structure of our galaxy.
Researchers at the University of Illinois Chicago are developing a community-based weight loss program for African American breast cancer survivors. The program aims to improve diet and physical activity habits, as well as reduce body mass index and weight-related health risks.
A study published in Cell Transplantation found that human umbilical cord-derived mesenchymal cells effectively reduced clinical and pathological severity of induced colitis in test mice. The treatment inhibited pro-inflammatory cytokine expression, indicating its potential for treating inflammatory bowel diseases.
A dirty bomb attack on downtown Los Angeles' financial district could lead to significant economic losses, with estimated costs of nearly $16 billion over a decade. The study found that the public's fear and risk perception would have a larger impact than the immediate damage, with employees demanding higher wages to return to work.
Researchers found that bacteria have a 'risk management' strategy to control mutation rate in key genes, decreasing the risk of detrimental mutations. The study provides insights into how disease-causing mutations arise and may be involved in cancer development.
A new study model has found that cerebral vessel function is altered in just 30 days of obstructive sleep apnea exposure, increasing the risk of stroke. The model developed by researchers at Baylor College of Medicine reveals a link between OSA and stroke, highlighting the need for early diagnosis and treatment.
A NASA animated video shows a week's worth of ash and gas clouds emitted from Mexico's Popocatepetl Volcano, with most debris blowing to the southeast. The volcano's alert level remains at 'Yellow Phase Three' due to potential explosive activity.
Researchers at UBC and VCH found that a senior's exercise program using resistance-training can improve executive cognitive functions, associative memory, and brain plasticity. The study suggests that resistance training can be an effective prevention strategy for dementia.
A recent study found that mammalian families in North America maintained similar niches throughout the past 56 million years, despite significant climate changes. The research suggests that family diversity played a crucial role in their ability to adapt and maintain larger ranges.
Researchers at Johns Hopkins identified a gene, methionine sulfoxide reductase (MSRA), that modifies the risk of newborns with cystic fibrosis developing neonatal intestinal obstruction. This study may lead to a better understanding of how intestines work and pave the way for identifying genes involved in secondary complications.
Researchers created animated characters, Briana and Damon, to communicate anti-violence messages to urban youth. The characters were developed in collaboration with community members and featured in Facebook videos aimed at reducing teen violence.
A Tulane research team found that applying high levels of oxygen to a severed bone facilitates bone regrowth, particularly when applied at the right time. This discovery may one day benefit injured soldiers, diabetics, and other accident victims with partial limb regeneration.