Add BrightSurf on Google Email

Science News for August 24, 2012


Moffitt Cancer Center researchers and colleagues identify PHF20, a regulator of gene P53

Researchers at Moffitt Cancer Center have identified PHF20 as a novel transcriptional factor that regulates gene P53, a crucial gene for normal cell growth and tumor suppression. The study found that PHF20 directly interacts with p53 and stabilizes it, allowing for its activation in response to DNA damage.

SourceH. Lee Moffitt Cancer Center & Research Institute·JournalNature Structural & Molecular Biology·DateAug 24, 2012

Modeling metastasis

Researchers used Active Shape Model to simulate fluid forces acting on breast cancer cells in blood flow. The study aims to develop new therapies targeting metastasis by understanding mechanical properties of cancer cells.

SourceAmerican Institute of Physics·JournalPhysics of Fluids·DateAug 24, 2012

Researchers describe new molecular interactions behind the inhibition of TGF beta-signaling

The study reveals that inhibitory Smads bind directly to their targets without requiring phosphorylation, constituting a crucial step in the regulation of gene transcription. This discovery sheds light on how organisms achieve balance between TGF-beta signaling pathways, critical for maintaining tissue and organism health.

Ancestral link places Mexican-Americans at greater risk for metabolic disease

A recent study found that Mexican-Americans with an ancestral link to Amerindian tribes have higher insulin resistance levels, a key indicator of several chronic conditions. The research suggests that ethnicity information is crucial in identifying individuals at high risk of disease, and that genetic markers can be used for personaliz...

Addressing the need for microscopic speed

Researchers have developed a digital microscope that creates high-resolution images at fast speeds, enabling scientists to study biological processes like cell activity in greater detail. The new device uses a programmable micromirror system to reject unwanted light and improve image quality.

SourceUniversity of Leicester·JournalPLOS ONE·DateAug 24, 2012

Only 2 percent of Canadians deny climate change

A recent survey conducted by IPAC-CO2 Research Inc. found that only 2% of Canadians reject the concept of climate change, while most believe it is real and caused by human activity. The survey also revealed divisions in opinions on how to address climate change, with some prioritizing cleaner cars and others supporting a carbon tax.