Researchers developed a novel technique to turn immune system killer T cells into more effective weapons by delivering DNA into instructor cells. The method proved effective in jumpstarting defective immune systems in immuno-compromised mice and human killer T cells, paving the way for potential cancer therapy.
Researchers created a new method using calculus equations to estimate acetaminophen overdose patient prognosis, predicting those who can survive with antidote treatment versus those needing a liver transplant. The study analyzed 53 patients and showed the method's accuracy in determining survival outcomes.
Researchers have successfully differentiated human dental pulp stem cells into liver cells using hydrogen sulphide, producing high numbers of pure cells. This breakthrough offers promising results for future liver-cell therapy and transplantation without the risk of teratomas or cancers.
Researchers have identified a gene responsible for Thrombocytopenia with Absent Radii (TAR), a rare inherited blood and skeletal disorder. The discovery enables the development of a medical test for prenatal diagnosis and genetic counseling in affected families.
TAK-875, a novel oral medication, enhances insulin secretion in a glucose-dependent manner, improving blood sugar control and lowering the risk of hypoglycemia. The study showed significant reductions in HbA1c levels across all TAK-875 doses, with higher efficacy rates compared to glimepiride.
Massachusetts General Hospital researchers isolated egg-producing stem cells from adult human ovaries, demonstrating that these cells can produce normal egg cells. The findings support the idea that female mammals continue producing eggs into adulthood.
Researchers at Stanford University School of Medicine discovered that common baker's yeast has engaged in promiscuous mating in fermentation vats, leading to a genetic mash-up. This unexpected behavior affects the flavor of wine and makes tracing lineage difficult.
Energy efficiency experts propose a new EU target of a 40% reduction in primary energy demand by 2050, arguing that radically improving building efficiency is crucial for reducing global greenhouse gas emissions. The proposed target aligns with the ambitions of the new Energy and Climate Change Secretary Ed Davey.
Researchers discovered the structure of type VI secretion system apparatus and proposed how it works by firing spring-loaded molecular daggers. The nano-weapon can pierce cell membranes and inject proteins, evading detection for decades with traditional electron microscopy.
Researchers found unique changes in hydrogen and boron isotopes in submarine volcanic glass near subduction zones, indicating ancient oceanic slabs can return to the upper mantle and interact with modern seawater. This discovery suggests hydrogen diffusion rates in the deep Earth may be slower than expected.
Researchers at MIT have developed a novel RNA interference method that delivers short interfering RNA (siRNA) using microspheres, overcoming the challenge of efficient delivery in the body. The new system shows promise for targeting specific genes in tumors and other diseased cells.
Researchers have analyzed ancient manuscripts from 9th-10th century Iraq to reconstruct the climate of the past. The study reveals abnormal weather patterns, including droughts and floods, as well as rare cold events such as hailstorms and snowfall in Baghdad.
Researchers at Georgia Institute of Technology have successfully squeezed a property called the nematic tensor, describing rubidium atoms in Bose-Einstein condensates. This achievement improves measurement precision for atomic clocks and magnetometers, with potential applications to quantum information systems.