A recent meta-analysis by CAMH found a complex relationship between alcohol consumption and ischaemic heart disease, with varying risks depending on gender, drinking patterns, and overall health outcomes. The study concludes that lower drinking limits for women are needed to inform safe drinking levels.
The Arctic is already experiencing the effects of dangerous climate change, with ecosystems and populations at risk. Experts demand rapid alarm signs to prevent abrupt changes and advocate for adaptive strategies.
Researchers at Stanford University School of Medicine have successfully converted mouse skin cells into neural precursor cells with high efficiency. This breakthrough could potentially refute the need for pluripotency and offer a more direct way to generate specific cell types for therapy or research.
Recent study finds that inhibiting JAK2 kinase does not benefit leukaemia patients, but blocking STAT5 signaling can prevent cell proliferation. This discovery challenges the approach to targeting JAK2 in CML treatment.
Researchers have rewritten the textbook on the location of the brain's speech processing center, discovering it is located in the left temporal lobe and superior temporal gyrus. The new findings suggest that language originated between monkeys and humans closer than previously thought.
Scientists at Arizona State University's Biodesign Institute investigated disease-causing E. coli strains, discovering they use plasmids to resist acidic conditions and form biofilms, critical for infection. The study aims to develop a vaccine capable of cross-protecting humans and birds.
Researchers have identified a new family of hypoxic regulator proteins that malfunction when dysregulated, contributing to the progression of serious diseases like cancer. This discovery may lead to the development of novel drug therapeutics to combat cancer and other oxygen-related disorders.
Dr. F. Michael Flasar, Dr. Anthony D. Del Genio and Dr. James Slavin recognized for their outstanding contributions to Earth and space sciences. Flasar's work on planetary atmospheres, including Titan's unique atmosphere, was highlighted as fundamental to understanding climate physics.
A lab study found that Gilenya, an MS treatment, reverses ventricular hypertrophy's symptoms and prevents fatal arrhythmias. Researchers discovered Pak1's role in heart disease and developed a potential new therapy.
Smoking doubles the risk of developing oesophageal cancer in people with Barrett's Oesophagus. A 13-year study involving over 3000 patients found those who smoked tobacco were twice as likely to develop cancer.
A new study by Michigan State University sociologist Hui Liu found that divorce hurts people's health more at earlier ages. The research journal Social Science & Medicine revealed that older people have more coping skills to deal with the stress of divorce.
Researchers identified genetic alterations affecting proteins known as histones in 48 pediatric glioblastomas, with 36% of cases featuring histone mutations. These mutations, which occur rarely in adult glioblastoma, may hold key to developing new treatments for the most malignant type of brain tumor.
A new NASA study finds that Earth's energy budget remained out of balance despite unusually low solar activity between 2005 and 2010. The planet continued to absorb more energy than it returned to space, with carbon dioxide levels needing to be reduced to restore equilibrium.
Key findings: DNDi highlights the need for enhanced research and development for new treatment and diagnostic tools for NTDs. The organization stresses that filling R&D gaps is crucial to achieving disease control or elimination by 2020.
A study published in the Journal of the American College of Cardiology has shown significant improvements in peak post-ischemic blood flow in the arm and leg, suggesting a potential novel approach to heart failure treatment. However, further exploration is needed due to conflicting data on exercise capacity and inflammatory markers.
Researchers found 40 rare melatonin receptor mutations that increase diabetes risk nearly sevenfold. The study highlights the importance of genome sequencing in personalizing treatment for diabetic patients.
A team of engineers led by Ioannis Poulakakis aims to create robots that can run like animals, enabling them to access areas inaccessible to conventional vehicles. Using biomechanics research, they seek to develop a family of systematic control strategies that work with the robot's natural dynamics.
A study published in the Canadian Medical Association Journal found that coroners are more likely to hold inquests for childhood deaths and deaths from medical complications. The research analyzed data on over 20,000 deaths in five Australian states and found a significant disparity between publicized and unpublicized inquests.
Researchers found that impurities in quantum dots and nanorods lead to poor light emission, but heating them removes impurities, boosting luminescence. This technique enables the synthesis of high-quality nanocrystals for applications like bio-imaging and solar energy.
A new University of Colorado Boulder-led study suggests that the Little Ice Age was triggered by a 50-year-long episode of four massive tropical volcanic eruptions. The onset of the cold period is believed to have been caused by an unusual sea ice-ocean feedback system originating in the North Atlantic Ocean.
Researchers analyzed past studies on cancer-related pain reduction and found that psychosocial interventions can significantly improve cancer patients' pain severity. Skill-based interventions and educational approaches were most successful in reducing pain and its impact on daily life.
A study by researchers from Walter and Eliza Hall Institute reveals that progenitor cells can develop into both megakaryocytes and red blood cells, rewriting the 'map' of blood cell production. The discovery has wide-ranging implications for understanding blood diseases and developing new treatments.
A new study published in Gastroenterology reveals that Barrett's esophagus patients who smoke are twice as likely to develop esophageal cancer. Tobacco smoking emerged as the strongest lifestyle risk factor for cancer progression in this patient group.
A nationwide study reveals that most young people who present to emergency departments with deliberate self-harm are discharged without receiving a mental health assessment. The study found that only 39% of patients discharged to the community received a mental health assessment while in the emergency department.
A new clinical trial combines two medications to address anxiety and physiological stress before, during, and after surgery. This approach aims to increase long-term survival rates by up to 300 percent in cancer patients.
Research reveals mammals reached maximum size after dinosaurs extinction, with sea mammals doubling time compared to land mammals, while extreme dwarfism occurred in just 100,000 generations.
A study published in Science suggests that plant biodiversity is crucial for maintaining ecosystem multi-functionality in drylands, which are vulnerable to desertification and climate change. The research found that increasing perennial plant species enhances ecosystem ability to store carbon and build nutrient pools.
Researchers at NOAA's Milford Laboratory have isolated a new probiotic bacterium, OY15, that significantly improves larval survival in oyster hatcheries. The study confirms the protective effect of naturally-occurring probiotic bacteria against bacterial disease and promotes healthy growth.
A recent study published by Wildlife Conservation Society reveals that livestock, not Mongolian gazelles, are the primary drivers of foot-and-mouth disease (FMD) outbreaks in Mongolia. The research found that FMDV antibody prevalence in gazelle populations mirrored the dynamics of FMD in livestock across the Eastern Steppe.
Research reveals that rates of size decrease are much faster than growth rates, with dwarfism occurring in just 100,000 generations. It takes at least 24 million generations for large-scale changes in body size to occur.
A recent study found that male doctors, those working in group practices, and those repeatedly seeing the same patients are at higher risk of burnout. The research used a validated measure to assess emotional exhaustion, depersonalisation, and reduced personal accomplishment among 564 GPs.
Researchers at University of Oxford and Harvard Stem Cell Institute have developed a common standard to describe and integrate large datasets from various fields, enabling better coordination of findings. The ISA Commons platform allows small research groups to store laboratory data without dedicated bioinformatics support.
A study published by Dr. Linda Pagani found that kindergarten attentiveness skills accurately predict later work-oriented behavior, with children who are well-engaged in the classroom exhibiting better self-control, confidence, and ability to follow directions.
Researchers combined scientific observations with Canadian Inuit traditional knowledge to determine Arctic killer whale behaviour and diet. Arctic killer whales primarily eat marine mammals, such as seals and bowhead whales, but little is known about their prey preference.
A new study published in Nature Climate Change provides a high-resolution map of aboveground biomass density for the world's tropical forests, leading to better tracking of changes in biomass density and improved estimates of carbon emissions. With this map, countries can accurately report their greenhouse gas emissions under the UNFCCC.
Research by Monash University reveals that producing high-quality sperm comes with significant health costs for males. The study found a negative correlation between sperm quality and immune function, suggesting males invest energy strategically to produce better sperm.
Researchers discovered that leprosy pathogen Mycobacterium leprae manipulates micro-RNs to evade the human immune system, specifically targeting vitamin D-dependent immune pathways. This finding offers new treatment avenues for infectious diseases.
Researchers used data from orbiting spacecraft to discover that energetic electrons are swept away by solar wind particles during periods of heightened solar activity. The findings aim to improve predictions of geomagnetic storms and protect satellites and astronauts.
A systematic review and meta-analysis found that a difference of 15mm Hg or more between arms is associated with increased risk of peripheral vascular disease, pre-existing cerebrovascular disease, cardiovascular mortality, and all-cause mortality. Measuring blood pressure in both arms should be part of routine care to identify patient...
Researchers have discovered nearly 80% of childhood brainstem tumors with diffuse intrinsic pontine glioma (DIPG) harbor mutations in genes involved in DNA organization. The mutations may play a unique role in other aggressive pediatric brain tumors, providing hope for new therapeutic targets.
Researchers identified 31 genetic regions associated with circulating metabolites, including biomarkers for cardiovascular disease and type 2 diabetes. The study provides new insights into the biological processes leading to common diseases, suggesting that detailed data on multiple metabolites can help elucidate these processes.
Researchers have confirmed that therapeutic ultrasound can be used as a male contraceptive, providing up to 2.5 months of protection in rats with two 15-minute sessions. The method was initially overlooked for decades due to concerns over its effectiveness, but new evidence suggests it may offer an alternative to existing options.
Researchers at Peninsula College of Medicine and Dentistry found that differences in systolic blood pressure between arms are associated with increased risk of vascular disease and mortality. A difference of 10mm Hg or more is linked to an increased risk of peripheral vascular disease, pre-existing cerebrovascular disease, and mortality.
A new genetic study has found a strong link between the body clock hormone melatonin and type 2 diabetes. Carrying rare genetic mutations in the MT2 gene increases a person's risk of developing type 2 diabetes six times, suggesting a direct link between melatonin regulation and insulin release.
Researchers found that stressful conditions increase chromosomal instability in yeast, allowing cells to rapidly adapt and acquire diverse aneuploid chromosome numbers. This stress-induced genetic variation enables yeast cells to thrive in environments with harsh conditions.
New research uses commercially available therapeutic ultrasound equipment to reduce sperm counts in male rats, resulting in infertility. The non-invasive treatment reduced sperm reserves far below levels seen in fertile men.
The Tasman Sea has become a global warming hotspot, with ocean temperatures rising two degrees warmer than 60 years ago due to intensified east-west winds and greenhouse gas emissions. A long-term monitoring network is needed to track these changes.
A genetic study found that pneumococcus bacteria can evade vaccines by swapping genome regions, making them invisible to the vaccine. The exchange of genome regions occurred through recombination, allowing the bacteria to quickly adapt and develop resistance.
A study found that people primed with feelings of love for their partner behaved more aggressively towards attractive rivals. Meanwhile, researchers discovered that men who confess love first tend to feel happier than women in the long run.
Rhode Island Hospital's new simulation-based training program, Project CLEAR!, aims to standardize communication skills among emergency department staff and enhance patient satisfaction. The program has been successfully implemented with nearly 400 staff members, resulting in improved quality of care, safety, and service.
Scientists analyze carbon isotopic composition in ancient rocks to understand conditions prior to the Marinoan glaciation, finding no link between changes and global glacial events. The research suggests alteration by freshwater as sea level fell is responsible for observed geochemical patterns.
A new study published in Perspectives on Psychological Science explores the use of pupilometry, a technique measuring pupil diameter, to gain insights into human behavior. By analyzing changes in pupil size, researchers can identify what people are paying attention to, shedding light on brain function and cognitive processes.
The Radiation Assessment Detector (RAD) has measured the radiation a human astronaut could be exposed to during a recent solar storm. The data collected will provide valuable information for future human space exploration, including insights into the physics of giant clouds and shielding provided by spacecraft.
A study published in the British Journal of Dermatology found that itching sensations vary by body site, with the ankles and backs exhibiting greater intensity and longer-lasting relief through scratching. Researchers suggest specific nerve fibers may be involved in pleasure-related sensations.
A study found that 30 children with bedwetting had excess stool in their rectums, despite normal bowel habits. After treatment with laxative therapy, 83% of the children were cured of bedwetting within three months.
Scientists at the University of Southampton have discovered the atomic structures of malarial enzymes responsible for vitamin B6 biosynthesis, paving the way for the development of new antimalarial chemotherapeutics. This research could lead to a breakthrough in combating malaria, which affects nearly 250 million people worldwide.
A new study found that transplant patients with head and neck cancer are more likely to be non-smokers and non-drinkers, and less likely to survive past one year of diagnosis. The risk for developing head and neck cancer is small, but the study highlights the need for regular screenings and aggressive treatment.
A new study found that the CAT questionnaire is a reliable tool for assessing COPD exacerbation severity, reflecting both exacerbation length and reduction in lung function. The CAT scores were also weakly related to systemic inflammatory markers and elevated in stable patients with a history of frequent exacerbations.
Research team led by Edward T. H. Yeh discovers that SENP1 regulates SUMOylation of STAT5, essential for lymphoid development of T and B cells. Without SENP1, STAT5 cannot be activated or recycled, leading to severe defects in immune cell development.
A new study has found that the lung clearance index (LCI) is a sensitive non-invasive marker of early lung disease in young children with cystic fibrosis. LCI was elevated in children with CF, especially in those with airway inflammation and Pseudomonas aeruginosa infection.