BWH researchers created a new method for controlled drug release utilizing air as a removable barrier. The rate of drug release correlates with the removal of the air pocket, enabling extended periods of controlled delivery.
Researchers develop a novel method for fabricating flexible organic semiconductors using a kitchen gadget-inspired approach. The technique improves the interface between the semiconductor and gate insulator, enhancing electrical performance and durability.
Researchers found that fat-derived stem cells thrive on stiff surfaces and form myotubes when matured, a crucial step in muscle development. These cells may offer new therapeutic possibilities for muscular dystrophy patients.
A new company formed around Michigan State University nanotechnology aims to detect deadly pathogens and toxins with handheld biosensors. The technology utilizes novel nanoparticles developed by MSU professor Evangelyn Alocilja, enabling rapid detection in the field without significant training.
Researchers at Washington University in St. Louis are conducting a landmark study to restore degraded glade habitats and ecosystems using fire manipulation techniques. The goal is to establish best practices for restorative ecology and mitigate biodiversity loss from small habitats, particularly rare species found nowhere else.
A Northwestern University study identifies a key player in the human immune system, revealing its crucial role in activating the immune response. The protein, STIM1, was found to regulate not only one function but also another critical step in immune activation.
Cyclone Funso's eye has filled with clouds, appearing ragged and 30 miles in diameter. The storm is expected to encounter stronger wind shear and cooler waters, leading to rapid weakening.
A University of Alberta researcher found that online undergraduate classes using text-based formats lack reflective engagement and facilitate communication lacking in joy, passion, flavour and urgency. Kanuka recommends integrating audio-visual technologies to better support students and create a more engaging community of learners.
A study of 1,074 participants across 16 studies found that people are worse at predicting their own emotions in absolute terms but better when compared to others. This relative accuracy might be useful in real-life situations, such as anticipating how clients will react to bad news
Researchers at Trinity College Dublin have developed a new vaccine to treat cancer by manipulating the immune response. The vaccine, which has shown high effectiveness in pre-clinical trials, overcomes obstacles that have hindered previous cancer vaccines.
Researchers at the University of Chicago are developing a new computational bioresearch tool that could lead to breakthroughs in understanding cellular motion. The Center for Multiscale Theory and Simulation will focus on predicting molecular interactions using advanced simulation capabilities, including coarse-graining techniques.
Researchers studied the role of immune responses in oncolytic adenovirus therapy and found that CD8+ T cells mediate antitumor efficacy. The study proposes a new therapeutic regime combining oncolytic adenovirus with immunotherapy.
A new study challenges the common notion that the amygdala is solely responsible for fear responses. Research suggests the amygdala processes events related to a person's current concerns, not just fear. This discovery has significant implications for our understanding of emotions and brain function.
A team of UT researchers has developed a novel physical form of proteins that can improve treatments for cancer and other diseases by overcoming the major challenge of drug delivery. The new approach enables safe, easy, and effective delivery of drugs to patients, revolutionizing treatment of cancer, arthritis, and infectious disease.
The Space Weather Laboratory will implement ensemble forecasting, producing up to 100 computerized forecasts simultaneously, improving the reliability of space weather alerts. This new capability is crucial for protecting astronauts and NASA spacecraft from potential harm during periods of increased solar activity.
Researchers at Instituto Gulbenkian de Ciência receive €2.2 million funding to investigate mechanisms behind 'tolerance to infection'. They aim to identify protective genetic programs controlling tissue damage in various diseases, paving the way for new therapeutic interventions.
Research from Jena University reveals that prejudice development peaks between 5-7 years of age, but well-designed prevention programs can effectively reduce biases. The study highlights the importance of diverse contacts in reducing sweeping generalizations and discrimination, especially for children from social minorities.
Researchers at OHSU have discovered a critical link between brain-derived neurotrophic factor (BDNF) and Rett syndrome, a neurological disorder affecting one in 10,000 baby girls. The study found that mutant neurons in the brainstem fail to produce BDNF, leading to breathing difficulties and other symptoms.
Researchers at University of York uncover key mechanism by which Vibrio cholerae gains foothold in the intestine, exploiting sialic acid for survival. The discovery could pave way for targeted treatments for the deadly intestinal disease that kills over 100,000 people annually.
A new study finds that desires for sleep and leisure are the strongest, yet hardest to resist, while those for media and work are the weakest. Resisting desires is not easy, as willpower becomes lower throughout the day, making it more challenging to make self-control efforts.
A Duke University-led study finds that 80% of high-endemicity areas in the Andes lack protection, with hundreds of rare species under threat from human activities. The research highlights the urgent need for conservation strategies to protect this unique region.
Research suggests that patients' perceptions of their illness significantly impact health outcomes, including functioning, healthcare utilization, and mortality. Effective health care treatment plans require consideration of a patient's beliefs about their illness, as they guide decisions about health and treatment adherence.
Tropical Cyclone Iggy is expected to strengthen as it approaches the Australian coastline due to low wind shear and warm waters. The cyclone has already triggered warnings and watches along coastal areas, with a Blue Alert posted for communities in Western Australia.
A new study analyzing 40 years' worth of voter data suggests that Americans perceive more political polarization than actual differences exist between parties. Contrary to popular belief, those who perceive greater polarization are more likely to engage in politics, attend rallies, or donate to a party.
Scientists at the Stowers Institute for Medical Research found that oligomers of a synapse protein are essential for forming long-term memory. The discovery supports a new theory about memory and may have implications for understanding diseases such as Alzheimer's and prion diseases.
The camera converts polarization images into false color images to represent different polarizations of light. Preliminary results suggest a complex visual world under water with evidence of communication and camouflage.
Researchers analyzed genetic data to find clues about human migration over 60,000 years ago. They found evidence for an ancient ancestry within Arabia, suggesting it was the first staging-post in the spread of modern humans around the world.
A new catalytic process at Cardiff University converts hydrocarbons from diesel production into oxygenated aromatics, including phthalic anhydride and coumarin. This breakthrough could lead to less waste and the creation of more useful chemicals for various industries.
The Broad Institute has received a $32.5 million grant to launch the Klarman Cell Observatory, which will decipher how biological decisions are made in health and disease. The Observatory aims to shed light on the inner workings of cells, leading to major treatment breakthroughs.
The study advances understanding of bruise composition and age through spectroscopic measurement and Monte Carlo modeling. Researchers developed a multilayered model simulating seven skin layers, providing clearer spectroscopic pictures of bruise composition and age.
Researchers discovered a newly acquired trait in some HIV-related viruses that allows them to degrade primate SAMHD1 proteins. The ability emerged first in Vpr proteins before the emergence of Vpx proteins.
Researchers found grape seed extract to be effective in killing head and neck squamous cell carcinoma cells without harming healthy cells. The extract damages cancer cells' DNA and prevents repair pathways from functioning.
Researchers discovered that certain ocean bacteria are tricked into using their own machinery to activate genes carried by viruses. The viruses inject DNA into stressed bacteria, which then support the virus' replication cycle. This co-evolutionary relationship reveals a sophisticated mechanism of gene regulation and exploitation.
Researchers from Penn State and Hallym University developed a system that uses LED lights to provide locational information, enabling shoppers to quickly find items in large stores. The hybrid system combines radio frequency transmitters with overhead LED lights to provide accurate location data.
A study found that intensity modulated radiation therapy (IMRT) improves quality of life among long-term survivors of head and neck cancer. Patients treated with IMRT reported better health-related quality of life compared to those receiving other forms of radiation therapy.
Two clinical trials launched by NIH aim to improve survival rates for out-of-hospital cardiac arrests. The trials compare different CPR approaches and treatments with medications, such as amiodarone or lidocaine, to determine which are most effective.
Researchers at the University of Manchester discovered graphene oxide membranes that can selectively remove water while blocking other substances, potentially leading to new applications in filtration and separation
Researchers at Scripps Research Institute found that a cell surface protein called CDCP1 protects tumor cells from apoptosis and promotes metastasis. The team identified plasmin as the key enzyme responsible for cleaving CDCP1, which triggers a signaling cascade blocking apoptosis and enabling cancer cells to colonize distant organs.
Researchers develop computer model to describe forces maintaining mangrove-hammock boundary, indicating large salt pulses may cause mangroves to invade hardwood hammocks. The model predicts changes in vegetation and freshwater supply due to storm surges and sea level rise.
A family history of psychiatric conditions such as autism and depression may shape a person's intellectual interests. The study found that students interested in humanities or social sciences were more likely to report a family member with mood disorders or substance abuse, while those interested in science and technical majors were mo...
Researchers found that glucocorticoid therapy can decrease citrullination and PAD4 enzyme levels in people with rheumatoid arthritis, leading to reduced inflammation. Treatment had no effect on methotrexate, but showed promising results for RA management.
A University of Houston vision scientist is developing new imaging techniques using the AOSLO device to better understand early changes in glaucoma. The research aims to enhance clinicians' understanding of glaucoma development and progression, leading to earlier recognition of structural damage and improved diagnostics.
Researchers at Purdue University have developed a new type of miniature medical sensor that uses acoustic waves from rap music to recharge and monitor pressure. The sensor can be used to diagnose incontinence and treat conditions such as aneurisms and paralysis, offering potential benefits over conventional implantable devices.
Cyclone Funso is a 400-nautical-mile-wide storm over the Southern Indian Ocean, moving south-southeast from the Mozambique Channel. NASA's Aqua satellite captured an image of the storm on January 26, showing its depth and extent.
A novel molecular process linked to neddylation has been found to be involved in the development of hepatocellular carcinoma, a type of liver cancer with poor prognosis. The study suggests that targeting this process could lead to potential therapeutic applications for patients with HCC.
A California occupational safety program can help prevent workplace injuries, but only if it is adequately enforced. The study found that businesses cited for noncompliance with the program's specific safety mandates saw a 20% decline in injury rates.
Researchers from the University of Manchester have discovered that commercially available graphite crystals contain micron-sized clusters of predominantly iron, which explain their weak signs of magnetism. This finding could be a breakthrough for utilising graphite as a bio-compatible magnet for medicine and biology.
Researchers at Michigan State University demonstrate how a new virus, Lambda, evolves to attack host cells through a new receptor. The study shows that four mutations are required for this innovation to occur, and natural selection plays an important role in the virus' evolution.
A new study suggests that a parent's education level can affect the mental health of their offspring. Higher levels of parental education are linked to fewer mental health issues in adult children.
Researchers have developed new interventions targeting influential students to reduce bullying, while increasing teens' interest in STEM courses through parental involvement. Additionally, interventions improving women's perceptions in engineering have shown promising results, highlighting the power of social-psychological approaches.
A new study led by Johns Hopkins Bloomberg School of Public Health found that physicians' body mass index (BMI) influences obesity diagnosis and care. Physicians with normal BMI were more likely to engage obese patients in weight loss discussions and diagnose obesity if they perceived the patient's BMI met or exceeded their own.
Researchers at URMC discovered a link between leukemia cells and bone formation, finding that leukemia alters the balance of osteoblast and osteoclast activity. The study suggests that targeting osteoclasts could be a potential treatment strategy for leukemia.
A recent study found that 7% of the US population between ages 14 and 69 has an oral HPV infection, with men being three times more likely to have it than women. The study also revealed that patients infected with oral HPV type 16 have a 14 times greater risk of developing head and neck cancer.
Tropical storm Iggy is growing in strength due to cloud top temperatures over -63F (-51.7C), indicating heavy rainfall and gusty winds along Western Australia's coast. Iggy is forecast to reach cyclone strength before moving south, with sea surface temperatures supporting further development.
Researchers at Georgetown Lombardi Comprehensive Cancer Center are studying whether high-risk HPV-positive patients with head and neck cancer should receive more or less chemotherapy. Their research suggests intensifying therapy could increase cure rates, but additional studies are needed.
A new study found that patients who quickly stop taking immunosuppressive prednisone after receiving a kidney transplant avoid experiencing serious prednisone-related side effects. The study also showed that rapid discontinuation of prednisone does not jeopardize the long-term survival of patients and their new organs.
A team of researchers has found a new method by which seawater can corrode nuclear fuel, creating uranium compounds that could potentially travel long distances in solution or as tiny particles. The discovery highlights the need to consider this phenomenon in future nuclear operations.
The study found that oral HPV infection was predominantly sexually transmitted and had peaks in different age ranges, with men having a significantly higher prevalence than women. Oral HPV prevalence was associated with several measures of sexual behavior, including the number of partners and current smoking habits.
A new study sheds light on the earliest stages of human migration, suggesting that modern humans first settled in Arabia on their way out of Africa. Genetic analysis of mitochondrial DNA genomes provides evidence for an ancient ancestry within Arabia.
Researchers found that standard radiation therapy with or without chemotherapy is less effective for HIV-positive head and neck cancer patients, with high recurrence rates of 69% and overall survival of 55%. This highlights the need for more research to develop tailored treatments that can improve outcomes for these patients.