A 1993 Chevrolet Corvette 40th Anniversary coupe was sold at the Barrett-Jackson Scottsdale Auction, raising $120,000 for cancer research at TGen. The funds support research into colon and prostate cancer in memory of Russ and Brian Jackson.
Recent geosphere research interprets Eocene–Early Miocene paleotopography in Nevada and examines the origin of the Colorado Mineral Belt. The study also investigates Miocene magmatism in the Bodie Hills volcanic field, California and Nevada, and compares mountain building processes in Alaska.
DIM inhibits ovarian cancer cell growth by blocking STAT3 activation and reducing IL-6 levels. The combination of DIM and cisplatin suppresses tumor growth in mice by an extra 50% compared to cisplatin alone.
Using computer simulations at the Ohio Supercomputer Center, researchers aim to engineer cyanobacteria to thrive in diverse illumination conditions. By understanding light sensing and harvesting in Anabaena sensory rhodopsin bacteria, they hope to develop new properties for alternative energy via microbial conversion of light energy.
A new study reveals the true extent of healthcare costs associated with living close to busy roads, estimating annual costs of $18 million in two Southern California communities. The 'asthma career cost' method takes into account childhood asthma cases and broad costs, exceeding average household income levels.
A Kaiser Permanente study of 190,000 girls and women found no increase in autoimmune conditions such as lupus or rheumatoid arthritis after receiving the quadrivalent HPV vaccine. The study tracked results from 2006-2008 and employed methods to ensure accuracy and compare vaccinated versus unvaccinated groups.
Researchers in the US have successfully cloaked a three-dimensional object standing in free space using a method known as plasmonic cloaking. The technique uses ordinary materials to bend light around objects, cancelling out scattering and rendering them invisible at all angles of observation.
The grant will explore the environmental factors influencing autism risk through epigenetic changes in DNA methylation. Autism Speaks aims to uncover avoidable risks and provide guidance for earlier diagnosis and improved treatments.
Researchers are developing new flight system programming that combines data analysis with aviation know-how to create safer skies. The project aims to improve the accuracy and timeliness of flight data, reducing the risk of accidents caused by outdated or incorrect information.
Researchers discovered a novel intracellular signaling pathway controlling stress-induced CRH gene expression, revealing a key role for Orthopedia protein in stress adaptation. This regulation is critical for neuronal adaptation and failure to activate or terminate the CRH response can lead to chronic pathological conditions.
Researchers have discovered that stem cells from patients with schizophrenia proliferate faster than healthy individuals, indicating dysregulation of the natural cell cycle. This finding provides a potential path to understanding schizophrenia and developing new treatments.
A recent study by Mars, Incorporated and partners reveals the extensive metabolism of flavanol compounds after consumption, challenging existing in vitro studies. This research provides a critical step forward in understanding how cocoa flavanols exert their circulatory and cardiovascular benefits.
The National Polar-orbiting Operational Environmental Satellite System Preparatory Project has been renamed Suomi NPP in recognition of Verner Suomi's contributions to weather forecasting and climate change research. The new name reflects the mission's objective of advancing scientific knowledge of Earth and improving weather forecasts.
A Rhode Island Hospital study found that deleting five personality disorders from the DSM-5 could result in false-negative diagnoses for patients. The proposed changes may affect up to 59 patients who would no longer be diagnosed with a personality disorder according to the current criteria.
The APOLLO trial demonstrated improvements in cardiac function, blood flow into the heart muscle, and reduced scar formation in patients with acute myocardial infarction. The study found a 52% reduction in left ventricle infarcted area and significant improvement of perfusion defects in ADRC-treated patients.
Neural stem cell derivatives from human pluripotent stem cells are prone to chromosomal instability, particularly with chromosome 1q, which has been linked to blood cell cancers and pediatric brain tumors.
The software highlights discrepancies between different types of understanding and helps children perform better in school. Children using the software made substantial progress in reasoning, especially with challenging concepts like object fall.
A study led by Durham University found that children with autism have intact inner speech mechanisms but often don't use them like typically developing children do. Teaching strategies to encourage inner speech may improve communication impairments and daily life skills.
A team of researchers discovered a well-preserved feather on Archaeopteryx's wing was black, indicating the presence of melanosomes that provided structural support. The feather structure is identical to that of modern birds, showing early evolution of wing feathers as early as 150 million years ago.
Researchers at the University of York have successfully recreated a process that could be responsible for the origin of carbohydrates in life. By using simple left-handed amino acids as catalysts, they produced predominantly right-handed sugars, shedding light on how these building blocks came to dominate nature.
A new NIH-funded study found that treating silent acid reflux does not improve asthma control in children. Researchers found that acid reflux medication, such as lansoprazole, can actually increase the risk of respiratory problems like sore throats and bronchitis.
A new analysis of 124 wetland studies reveals that restored wetlands rarely reach the quality of their natural counterparts. After 50-100 years, they are still 23% less in terms of carbon resources and have a 26% lower variety of native plants.
Researchers found that older forests with specific fungi are essential for orchid survival and recovery. The study suggests that planting new forests may not be enough to save endangered orchids without the right fungal conditions.
Five Portuguese scientists have been awarded prestigious funding by the US-based HHMI for their innovative research projects. The awardees, who are based in Portugal, will receive $650,000 over five years to work on diverse areas of neuroscience and parasitology.
A team of researchers found that brown fat in adult men burns energy to generate body heat when exposed to cold temperatures, but not at warm temperatures. This discovery has significant implications for the human obesity epidemic, suggesting that increasing brown fat is unlikely to lead to weight loss and instead highlights the need f...
A Queen's University study found that thinking about religion enhances self-control in individuals, even after unrelated tasks have depleted it. The research suggests that religion can serve a practical function in society beyond its traditional role as a source of transcendence and fear of death.
Scientists at the University of Nottingham have successfully altered root growth in plants by controlling a key regulatory protein, WRKY23. This breakthrough could lead to improved crop yields and resistance to parasites under varying environmental conditions.
Researchers at EPFL have successfully developed a 3D chip with multiple processors stacked vertically, increasing efficiency and processing power. The chip is connected using thin copper microtubes through tiny openings called Through-Silicon-Vias, reducing data exchange time.
A study found that women with invasive epithelial ovarian cancer and a BRCA gene mutation had improved 5-year overall survival, with BRCA2 carriers having the best prognosis. The study analyzed data from 26 observational studies and included 1,213 cases with pathogenic germline mutations in BRCA1 or BRCA2.
Scientists have found microbial succession in microbes on deep-sea hydrothermal vents, where life adapts to replace extinct communities with iron and sulfur-rich environments. Researchers at USC uncovered evidence of ecological succession on dormant vents, replacing heat-dependent microbes with new species.
Gene therapy is poised to disrupt traditional treatment methods with its effectiveness in treating diseases such as hemophilia B. The technology has demonstrated feasibility and is expected to bring significant changes to the healthcare marketplace.
A study published in PLoS Medicine found that individuals with access to sanitation facilities are half as likely to contract roundworm, whipworm, and hookworm infections. Regular latrine use further reduces the risk of infection by an additional 5%.
A new study found that eating cocoa can help prevent intestinal complaints linked to oxidative stress and colon carcinogenesis. The study, published in the journal Molecular Nutrition & Food Research, showed that a cocoa-rich diet reduced aberrant crypts in the colon and improved antioxidant defenses.
A study in PLOS Medicine found that tobacco smoking and high blood pressure account for the majority of deaths among Japanese adults. Reducing exposure to these risk factors could extend life expectancy by 1.4 years, according to researchers.
A genetic variation has been found to increase the risk of metabolic syndrome in children taking second-generation anti-psychotic medications, characterized by high blood pressure and elevated fasting blood sugar levels. The study aims to prevent and manage metabolic complications associated with these medications in childhood.
A saliva test used to diagnose HIV has been found to be comparable in accuracy to the traditional blood test, according to a new study. The test showed high sensitivity and specificity rates of 99% and 97%, respectively, making it a promising tool for HIV diagnosis, particularly in high-risk populations.
The article proposes three areas of legal liability for ghostwriters: reliance on false safety and efficacy data, inducing government reimbursement under false pretenses, and anti-kickback statute violations. Guest authors' participation in ghostwritten articles may also lead to claims of fraud on the court against pharmaceutical compa...
A study found that adding proton pump inhibitor lansoprazole to anti-inflammatory treatment did not improve symptoms or lung function in children with poorly controlled asthma. The use of lansoprazole was associated with increased adverse events, including upper respiratory tract infections and bronchitis.
Researchers have identified a new pathway that targets the root cause of glioblastoma resistance, paving the way for more effective treatments. By understanding how this complex signaling process works, scientists hope to develop novel therapies to improve patient outcomes and extend survival rates.
A Rice University research team made graphene suitable for organic chemistry applications by attaching various molecules to its sheets, enabling advanced chemical sensors and electronic circuits. The hydrogenation process transformed graphene into a semiconducting superlattice, allowing for tailored functionality.
Researchers have identified the 'speed gene' in modern Thoroughbred racehorses as originating from a single British mare around 300 years ago. This finding was made by analyzing DNA from hundreds of horses and is significant for understanding the evolution of racing strategies.
The new guidelines provide a contemporary, evidence-based approach for investigators conducting randomised, controlled migraine clinical trials. Key findings include the importance of patient selection, trial design, and evaluation of results in both acute and preventive settings.
EMBL Monterotondo researcher Rocio Sotillo has won a $650,000 Howard Hughes Medical Institute award to support her research on cancer and chromosomal errors. She will use the prize to establish an independent research programme and develop new ways to grow lung cancer cells in three-dimensional cultures.
Studies found that teen passengers, particularly thrill-seekers with weak perceptions of driving risks, can distract drivers and promote aggressive behavior. Experts recommend limiting passenger numbers for teens during their first year of driving to reduce crash risk.
A UC Riverside-led team has identified a property of bilayer graphene that becomes insulating when the number of electrons on the sheet is close to zero. This finding suggests promising routes for digital and infrared technologies, including trilayer and tetralayer graphene with larger energy gaps.
A new NIH grant could lead to a potential treatment for obesity-related diseases. Preliminary studies show that controlling a specific gene pathway can prevent long-term inflammation and its associated diseases.
A study on marine turtle mating patterns reveals that a population of endangered green turtles in Northern Cyprus is protected from the disproportionate number of females being born due to global warming. The researchers found a large number of males siring offspring with multiple females, reducing the risk of inbreeding.
A new study published in Radiology found that preoperative MRI helps surgeons make informed decisions about nerve-sparing procedures for men with prostate cancer. The imaging modality changed the surgical plan in 28% of patients, without compromising oncologic outcomes.
Despite efforts to identify and retract plagiarized papers, a significant percentage remain untagged, raising concerns about the prevalence of scientific plagiarism. Researchers like Harold Garner have called for improved detection systems to address this growing issue.
Scientists have developed a new technique that allows them to create detailed 3D images of individual proteins using cryo-electron microscopy. This breakthrough enables researchers to study the flexibility and movement of proteins, which is crucial for understanding their function and developing new drugs.
The University of Hawaii will develop a virtual reality software application to help jobseekers with disabilities navigate the world of job hunting and adapt to the workplace. The project aims to improve employment opportunities for people with disabilities, including veterans with traumatic brain injury.
A University of Michigan report found that young adults in Generation X were moderately concerned about the flu and followed the issue closely. Despite a low vaccination rate, they responded accordingly by being well-informed and taking actions to protect themselves and their families.
Researchers have found that brown fat in healthy adult men burns energy to generate body heat during cold exposure, but not at warm temperatures. This discovery has significant implications for combating the human obesity epidemic and suggests that increasing brown fat may not lead to weight loss.
Modules differ in form and function, allowing for division of labor among specialized modules. The study identifies necessary conditions for division of labor to evolve, including positional effects and synergistic effects between differentiated modules.
Adolescents who consume high amounts of fructose are at increased risk for cardiovascular disease and diabetes, according to a recent study. The researchers found that heavy consumers of fructose had lower levels of protective fats like HDL cholesterol and adiponectin.
Researchers use metal-organic frameworks (MOFs) to remove volatile radioactive gas from spent nuclear fuel, reducing waste and increasing the possibility of clean nuclear energy production. The discovery could be applied to nuclear fuel reprocessing or cleanup of nuclear reactor accidents.
A study found that children exposed to perfluorinated compounds, commonly used in food packaging, had lower antibody responses to routine childhood immunizations. The most common PFCs, such as PFOS and PFOA, were associated with decreased antibody concentrations, indicating potential immune system deficits.
A study by James Burton and team found that stressed supervisors who engage in moderate exercise report less abusive behavior towards their subordinates. The research suggests that wellness programs with exercise components can help smooth out relationships between supervisors and employees.
A new study suggests that GABA deficits in the brain may trigger disturbances in the endocannabinoid system, which is responsible for regulating substances similar to cannabis products. The research also found that cannabis use can alter GABA activity in the brain.
A study published in JAMA found that exposure to perfluorinated compounds (PFCs) was associated with lowered immune responses to childhood vaccinations. The research, which analyzed data from Faroe Island children, suggested a link between PFCs and reduced antibody levels, posing a potential threat to public health.