Researchers discovered rare variations in the DCTN4 gene among cystic fibrosis patients with early, chronic airway infections. The study suggests that exome sequencing can identify genetic factors behind complex traits like obesity and heart disease.
A new study reveals how sunburn occurs when UV radiation damages RNA in skin cells, triggering an inflammatory response that can lead to healing and potentially even cancer. The discovery may lead to the development of treatments that block this process without exposing patients to harmful UV light.
Medical Developments International (MDI) has signed a technology deal with CSIRO to develop a new production process for the pain-relieving drug Penthrox, known as the green whistle. The partnership aims to reduce production costs and enable large-scale production for global sales in the UK and Europe.
Astronomers have confirmed the first known 'middleweight' black hole, HLX-1, using observations with CSIRO's Australia Telescope Compact Array. The black hole is estimated to be around 20,000 to 90,000 times the mass of the Sun and lies in a galaxy called ESO 243-49.
Children's recovery from pediatric brain injury extends beyond medical care to involve the entire circle of family, friends, and healthcare providers. Recent research highlights the importance of 'family-centered' approaches and innovative interventions to promote self-worth, education as rehabilitation, and community reintegration.
A study analyzing 235 types of rice found its glycemic index (GI) varies greatly among types, with most scoring a low to medium GI. This allows consumers, including those with diabetes or at risk, to select rice varieties for a healthy diet.
Researchers developed two somatostatin vaccinations that reduce body weight and increase energy expenditure in diet-induced obese male mice. The vaccines induce antibodies to somatostatin, effectively removing inhibition on growth hormone and insulin-like growth factor-1.
Researchers at Brigham and Women's Hospital have discovered a cell-signaling molecule, interleukin-9, that inhibits melanoma growth in immune cells. High expression of this molecule in TH17 cells provides significant resistance to melanoma tumor growth.
Researchers discovered that E. coli uses yersiniabactin to steal copper from host cells, allowing the bacteria to grow and reproduce. This finding could lead to new treatments for serious urinary tract infections. By blocking this thievery with a drug, patients' chances of fighting off infections may significantly improve.
Researchers have identified Lyl-1 as a crucial transcription factor in producing early T-cell progenitors, which are the first cells on the path to becoming active T-cells. Without Lyl-1, these cells are severely impaired, and mice lacking the gene exhibit T-cell deficiency and leukemia-like symptoms.
A new study reports that girls' math performance is more likely to be affected by math anxiety than boys', despite both genders experiencing lower math scores. Higher levels of math anxiety in girls were found to be a significant indicator of their poor performance.
Researchers used electron holography to capture images of electric fields created by ferroelectric materials' atomic displacement. This technique could guide scaling up these materials and ushering in a new generation of advanced electronics.