A team led by Professor Kevin Shakesheff has created an artificial 'womb' that allows for the growth of embryos outside the body, revealing new aspects of embryonic development. By observing critical stages in real-time, scientists have gained insights into the process of head formation and the role of pioneer cells in leading migration.
Scientists from CDF and DZero collaborations achieve precise measurement of W boson mass, an important constraint on the theorized Higgs boson. The new result provides a rigorous test of the Standard Model, which describes the properties of matter and its interactions.
Researchers from the University of Victoria have developed a new 3D stem cell culture method, enabling scientists to study cell behavior in conditions similar to those in the body. This breakthrough has significant implications for regenerative medicine and other fields.
The new measures aim to standardize and improve results from NIH-funded asthma research, helping to reduce disparities in treatment and outcomes. The proposed outcomes categories include symptoms, exacerbations, biomarkers, lung function, quality of life, and healthcare utilization.
A new study by scientists from CIRES and NOAA found that gasoline vehicles produce more secondary organic aerosols (SOA) than diesel vehicles in urban environments, contributing 80% or more to SOA concentrations. This finding suggests a decrease in gasoline emissions could significantly reduce SOA concentrations on a global scale.
Researchers at UC Davis found that R-loops prevent methylation at CG island promoters, which are essential for 60% of human genes. This breakthrough could lead to treatments for autoimmune diseases by reversing cytosine methylation.
Tropical Storm Irina weakened due to interaction with southwestern Madagascar and wind shear. The storm is expected to intensify over the warm waters of the Mozambique Channel before making landfall.
A scientific method paper and video demonstrating a laboratory technique used to study mitochondrial dysfunctions in Alzheimer's disease and other disorders has gone viral. The technique, which measures the electrical potential across the inner mitochondrial membrane, has been accessed by more than 14,000 scientists worldwide.
The American College of Rheumatology has released the first classification criteria for polymyalgia rheumatica, aimed at improving diagnosis and treatment. The new criteria define key disease features that help identify patients with this condition.
The research reveals that ocean acidification is happening at a faster rate than in the past 300 million years, with severe effects on marine organisms. Acidification harms shell-building species like corals and molluscs, as well as phytoplankton species, which are essential to the marine trophic network.
A University of Alberta research team discovered that ozone-treated water can eradicate infectious proteins from cattle brain matter, providing a potential solution for decontaminating wastewater and sterilizing neurosurgical equipment. This breakthrough technique offers improved prion removal methods in meat processing plants and surg...
Researchers have found that Plexin-B1 represents a new candidate therapeutic target to treat patients with breast cancer found to overexpress the molecule ErbB-2. Overexpression of ErbB-2 led to activation of Plexin-B1, promoting metastatic cell characteristics in human breast cancer cells and reducing prognosis in human patients.
Researchers found that a memory training strategy can help people with mild cognitive impairment (MCI) remember specific information, such as object locations. The technique showed increased activity in the hippocampus, a critical brain region for forming new memories.
Yale researchers found that megakaryocytes grow 10-15 times larger than other blood cells through endomitosis, but a malfunction in this process may lead to leukemia. The discovery reveals the formation of functional platelets and provides clues about what may go awry to transform normal megakaryocytes into malignant leukemia cells.
A 10-year study of living kidney donors in Ontario found no increased risk of heart disease compared to the general population. Despite reduced kidney function, donors had a lower risk of death and heart disease than non-donors.
A combination therapy of dendritic cell implants and radiotherapy was found to be effective in inducing tumor-specific immune responses in 52.9% of trial patients with high-risk soft tissue sarcomas. The treatment resulted in dramatic increases in immune T cells in the tumors, leading to significant clinical benefits.
Scientists developed a computer model to accurately emulate leaf growth from a bud, discovering simple rules controlling leaf shape. The model, created using molecular signals and an inbuilt orientation system, can now help identify genes controlling leaf shape and understanding plant development.
A University of Michigan Health System study found that living in a poor neighborhood worsens chronic pain for young adults. The research highlights the importance of considering structural barriers and access to resources in pain management.
Researchers at UC Berkeley have discovered that graphene is an excellent active media for optical modulators, promising faster data transmission and computing. The graphene-based modulators can perform at speeds up to 10 times faster than current technology, enabling applications such as high-definition streaming on smartphones.
A new study suggests that bacteria can communicate through physical contact, using a system of 'cellular communication' to coordinate functions. The researchers found that certain bacteria require specific proteins to bind and interact with each other, facilitating this touch-dependent language.
A WSU researcher found that environmental toxicants, including jet fuel and pesticides, can cause disease-causing compounds in offspring for up to three generations. The study demonstrates the potential for transgenerational disease development through epigenetic changes.
The GPM mission, a joint effort between NASA and JAXA, aims to improve climate, weather, and hydrological predictions by providing accurate precipitation measurements from space. The GMI instrument will play a crucial role in measuring precipitation and environmental forecasting, particularly during extreme weather events.
Berkeley Lab scientists create thinnest possible films of gold-silicon eutectic alloys and observe peculiar patterns of circles surrounded by blisters. The team finds that thinner gold layers lead to faster reaction rates and the formation of perfect squares in the center of the circular denuded zones.
A study published in European Journal of Nutrition found that serum taurine intake was associated with significantly lower coronary heart disease risk among women with high total cholesterol levels. Higher taurine intake was linked to a 60% lower risk of developing or dying from CHD.
Researchers have discovered that a bacterial photoresponsive protein can resist the adhesion of mammalian cells, opening up new possibilities for biosensor applications and surface modification in regenerative medicine. This finding provides a novel non-fouling substance that distinguishes it from other anti-fouling substances.
The study has provided novel insights into the regulatory processes that help Bacillus subtilis cells maintain their metabolism in prime condition. It identified 512 new potential genes in the bacterium and has implications for biotechnology, pharmaceutical, and medical industries.
Scientists at the Diabetes Research Institute developed an oxygen-generating biomaterial to enhance insulin-producing cell survival. The material, PDMS-CaO2, generates critical oxygen for up to six weeks, mimicking the native pancreas environment.
Researchers at UCLA have discovered a novel compound called CLR01 that prevents α-synuclein protein aggregates from forming, stopping their toxicity and even breaking up existing aggregates in the brain. This breakthrough holds promise for slowing or stopping Parkinson's disease progression and may lead to human clinical trials.
A team of researchers identified a beta-1 integrin signaling pathway crucial for HNSCC resistance to radiotherapy. Inhibiting this pathway sensitized cells to radiation and delayed tumor growth in mice.
A phase I clinical trial of patients with advanced pancreatic cancer showed promise with rigosertib, achieving stable disease in 11 of 19 patients for a median duration of 113 days. The drug targets PLK1 and PI3K signals that allow cancer cells to divide rapidly.
Researchers at Linköping University have developed a new method for stronger dental implants by using a drug coating that allows titanium screws to adhere to the bone better and faster. After six months, 15 out of 16 patients showed significantly improved fixation of their treated implants.
Scientists study the impact of asymmetrical light input on cerebral hemispheric specialization and interhemispheric cooperation in bird embryos. The results show that information exchange is impaired without light-stimulation, which may help understand developmental disorders like ADHD or autism.
Researchers identified PDGF-B signaling in trophoblasts as a vital component of the placental niche, supporting blood stem cell generation and expansion without promoting differentiation. This discovery provides new insights into regulating EPO expression and governing the fates of blood stem cells during development.
A study by University of Bristol researchers found that relying solely on improved water source type oversimplifies the measure of safety, leading to substantial underestimations in four developing countries. The adjustment increased estimates of people without access to safe drinking water in Ethiopia and Nigeria by millions.
A study published in Stroke found that long-term diabetics are at a higher risk of stroke, with the risk increasing by 3% each year and tripling for those with diabetes for 10 years or more. The study highlights the chronic nature of diabetes and its impact on blood vessels over time.
A study by UNC Health Care researchers found that a supercharged version of the protective protein focal adhesion kinase (FAK) can reduce heart attack damage by 50% in mice. The enhanced protein, called SuperFAK, was engineered to activate stronger survival signals and deactivate at the right time, reducing permanent heart damage.
A team of Italian and Swedish researchers has successfully transmitted two twisted radio waves across the waters of Venice, demonstrating a solution to the problem of radio frequency congestion. By twisting radio waves into fusilli pasta shapes, they were able to transmit multiple channels of information on the same frequency band.
Researchers from UT Southwestern Medical Center predicted and confirmed how E. coli bacteria hijack a cell's sense of direction by manipulating actin polymers. This study provides new insights into the regulatory mechanisms controlling disease-causing agents and normal mammalian cell behavior.
A large study found that postmenopausal women with higher trans fat intake have an increased risk of ischemic stroke. Aspirin use was shown to reduce this risk. The study, published in Annals of Neurology, highlights the importance of following a diet low in trans fats and adding an aspirin regimen to help women reduce their stroke risk.
Kessler Foundation partners with Ekso Bionics to test the wearable, robotic battery-powered exoskeleton's potential in rehabilitation research. Scientists will study its impact on circulation, bone density, and overall health.
Researchers have developed a modified protein, SuperFAK, that reduces cell damage after heart attacks by 50 percent without causing inflammation. The study suggests this protein may protect the heart during chemotherapy or following a heart attack.
Scientists at Whitehead Institute have made a breakthrough in understanding planarian stem cells, discovering genes that regulate two main functions: differentiation and renewal. The study, published in Cell Stem Cell, provides insights into the molecular mechanisms underlying regenerative medicine.
By mimicking the tail propulsion of a swimming fish, researchers created a biomimetic robotic fish that attracted and led golden shiners. The robot's movement patterns induced slower tail movements in followers, allowing them to benefit from the leader's energy savings.
A new UC Davis study finds that the increase in childhood obesity among California school children has slowed from 2003 to 2008. The study suggests that expanded fitness testing and outreach efforts are needed to address the persistent obesity trend among younger children.
Despite making significant strides in providing affordable access to basic healthcare, China still faces challenges such as waste and poor quality in public hospitals. The authors recommend reducing wastage through innovative payment incentives and governance structures.
Scientists discovered 13,435- to 13,738-year-old marks on a Jefferson's Ground Sloth femur, indicating prehistoric humans hunted or scavenged the animal. The findings are the oldest evidence of human activity in Ohio and provide new insights into the lives of prehistoric Ohioans.
Researchers found that induced hyperammonaemia significantly increases daytime sleepiness in patients with cirrhosis. Higher blood ammonia levels reduce the ability of cirrhotic patients to produce restorative sleep. This study suggests that reducing daytime sleepiness may result in improved sleep at night.
Indiana University researchers have discovered that specific types of RNA polymerase enzymes differ in function based on variation in their protein subunits. This finding reveals the importance of subunit composition in selecting which genes are silenced or expressed, with implications for understanding genetic disorders and diseases.
A study published by the American Society of Nephrology found that weight-loss surgery is safe for chronic kidney disease patients who are obese, with complication rates below 10%. Maintaining weight loss remains challenging for CKD patients due to limited exercise abilities and eligibility restrictions for kidney transplants.
Japanese researchers have developed a spectrally efficient, scalable elastic optical transport network architecture called SLICE to address growing IP traffic demands. The technology enables adaptive spectrum allocation, providing significant savings of network resources and increased capacity.
A study found that 75.94% of deceptive ads linked to health were in the 'health' category, followed by 'beauty and hygiene'. Researchers claim most provisions are not fulfilled, including banned practices like fictitious doctor interviews.
Researchers assessed climate change events over 300 million years, finding current ocean acidification is potentially unparalleled. Laboratory experiments suggest impacts on marine organisms, including slower growth and dissolution of carbonate shells.
Research reveals that some Scandinavian conifers survived the harsh ice age climate in small ice-free pockets for tens of thousands of years. The study found two distinct types of spruce trees with different histories, which could have economic significance for tree plantation owners.
A study of 87,025 postmenopausal women found that those consuming the most trans fats were 39% more likely to have an ischemic stroke. However, regular aspirin use may counteract this risk, with no association found between trans fat consumption and stroke risk among aspirin users.
A recent study published in Mayo Clinic Proceedings found that robotic surgery offers a less invasive alternative to traditional treatments for oropharyngeal cancer, resulting in high survival rates and improved patient quality of life. The treatment preserved patients' ability to swallow and maintained excellent speech performance.
A recent study found that boys' initial enthusiasm for upper secondary school gives way to cynicism and negativity as they progress. Girls experience a sense of inadequacy, which may lead to depression later in life. The study highlights the importance of effective stress management and supportive environments to promote positive growth.
A new study finds that the world's oceans may be turning acidic faster today from human carbon emissions than during four major extinctions in the last 300 million years. This could lead to the loss of organisms such as coral reefs, oysters, and salmon. The ocean acidification rate is at least 10 times faster than 56 million years ago.
A recent study suggests that US radiation residents' curricula for business practice and health care policy are in need of improvement, with most programs offering variable topics and educational time. The study's findings indicate that current curricula may be suboptimal, highlighting the need for further commitment and innovation.
Researchers found that wine experts were more sensitive to bitter tastes than non-experts, suggesting their ability to discern small differences in wine may be innate. This could mean that expert recommendations are too subtle for average consumers to sense.
A recent study found that labeling vegetable content in snack foods does not alter taste preference in children. Instead, introducing a variety of vegetables may be more effective in promoting consumption. The study enrolled 68 elementary and middle school children and tested their preferences for labeled versus unlabeled samples.