Research teams compared climate simulations to assess drought, water scarcity and river flooding impacts. The study found that frequency of drought may increase by over 20%, while 40% more people are at risk of absolute water scarcity without reduced greenhouse-gas emissions.
Palliative care consultant Claud Regnard argues that the Liverpool Care Pathway was unfairly maligned and that its demise will not improve end-of-life care. He rejects recommendations to replace it with an 'end of life care plan', citing lack of evidence for its effectiveness.
Researchers have discovered cellulose nanocrystals with remarkable mechanical properties, including stiffness comparable to steel. These tiny structures, abundant in nature, offer a potential green alternative to carbon nanotubes for reinforcing materials.
Researchers from the University of Pennsylvania have discovered a way to reduce disease toxicity associated with Lou Gehrig's disease in animal models. By targeting stress granules and modulating cellular structures, they slowed neuron dysfunction and showed promise in mammalian cells.
A new study analyzed the diet and digestion of cows, chickens, and pigs to determine their impact on climate change. The research found that animal diets vary greatly depending on the region, with some animals requiring more food to produce a kilo of protein than others.
The researchers created artificial nanoassemblies inspired by plant photosystems, which may collect and convert energy. They successfully joined individual units into larger arrays, enabling complex functional nanosystems with applications in Raman spectroscopy and catalytic processes.
A new CU-Boulder study found that toddlers who go to bed later than their melatonin increase have difficulty settling down at night. Toddlers with longer intervals between melatonin release and bedtime take longer to fall asleep and experience increased bedtime resistance.
Researchers at Northwestern University found that heavy marijuana users had abnormal changes in their brain structures related to working memory, performing poorly on memory tasks. The study suggests that chronic marijuana use may contribute to changes in brain structure associated with schizophrenia and potentially impair motivation.
Researchers at Wake Forest Baptist Medical Center are using optogenetics to study the neurochemical basis of addiction. The technology allows them to control specific populations of brain cells using light, providing new direction on patterns of dopamine cell activation that may be most effective to target alcohol drinking.
Researchers at Karolinska Institutet have successfully treated two babies in utero with mesenchymal stem cells, a type of connective tissue cell that can form and improve bone tissue. The treatment was administered to babies born with osteogenesis imperfecta, a rare congenital bone disease causing stunted growth and repeated fractures.
A study by UC Riverside-led team found that moderate alcohol consumption can bolster our immune system and potentially fight infections. The finding could lead to new interventions to improve vaccine responses, benefiting vulnerable populations.
Four University of Texas at Arlington faculty members - Frank Lewis, Carolyn Cason, Ron Elsenbaumer, and Vistasp Karbhari - have been elected as National Academy of Inventors fellows. They are recognized for their innovative work in various fields, including electrical engineering, nursing, chemistry, and mechanical engineering.
Researchers evaluated potential age-promoting compounds using a novel mouse model, finding that UV light exposure and cigarette smoke increased p16INK4 expression, while a high-fat diet did not accelerate this process. This study demonstrates the utility of the p16LUC mouse model for evaluating age-promoting agents.
The AIDS Clinical Trial Group (ACTG) Network has received a seven-year, $140 million NIH grant to support its ongoing research. The funding will enable the network to conduct clinical trials in resource-limited settings and develop novel therapeutic interventions for HIV-associated inflammation.
A mathematical model recreated the positions and movements of individual emperor penguins in a huddle, showing that an individual penguin only needs to move 2 cm for its neighbor to react. The model revealed how travelling waves propagate through the entire huddle, keeping it dense and protecting the birds from the cold.
Stanford researchers have made a breakthrough in developing a universal flu vaccine by targeting the protein stem rather than the head of a critical protein. This approach aims to offer broader protection against different strains of flu and potential multi-season immunity.
Astronomers have successfully imaged individual stars in a nearby binary star system using a new instrument that combines adaptive optics and interferometry.
A comprehensive new checklist aims to fill the need for practical steps and resources in guideline development. The checklist, published in CMAJ, includes 18 topics and 146 items with links to resources and training materials.
A protein complex named mTORC1 is essential for jumpstarting the immune response during the first 24 hours of an infection. It helps ensure that newly activated T cells have the energy needed to launch proliferation and produce specialized T cells.
Senescent cells, a key mechanism of aging, have been identified by researchers. They found that satellite DNA unravels as cells enter senescence, leading to cell division inhibition. This discovery could lead to new treatments for cancer and age-related diseases like Progeria.
Scientists have discovered 'superbugs' carrying multidrug-resistant bacteria in treated wastewater from two plants in northern China. The study reveals the microbes breed and spread their dangerous cargo, highlighting a significant public health risk.
A 1.4 million-year-old fossil hand bone from East Africa has revealed a modern human-like hand anatomy, bridging the evolutionary gap between humans and their nonhuman primate ancestors. The discovery indicates that early humans possessed dexterous hands capable of precise tool use.
A recent study published in Nature has found a significant increase in Pacific nitrogen content over the past 1,000 years, tied to climate change. The research uses deep-sea corals as natural recorders of changes in biogeochemical cycles, revealing a dramatic long-term shift in the Pacific ecosystem.
Researchers at Chalmers University of Technology have discovered that misfolded amyloid proteins react to multiphoton irradiation, opening up possibilities for new materials and technologies. These protein aggregates can be tuned for specific purposes and are as hard as steel, but with unique characteristics.
The National Institute of Allergy and Infectious Diseases (NIAID) has named leadership groups and clinical trials units to lead the restructuring of HIV/AIDS clinical trials networks. The new structure aims to increase collaboration, expand research scope to include co-infections, and create transparent mechanisms for idea solicitation.
New research links fracking chemicals to hormone disruption and reproductive issues in humans nearby. Water samples from drilling sites showed high levels of endocrine-disrupting chemicals (EDCs), which can interfere with hormones and increase health risks.
A team of researchers conducted the first-ever clinical study on computer security, exploring the impact of technological and human factors on malware attacks. The four-month study involved 50 subjects and found that technically sophisticated users were more at risk, contradicting the notion that they should have a 'Internet license'.
New research suggests that global warming of four degrees or more will lead to a saturation point for vegetation's ability to absorb CO2, resulting in a decrease in the 'carbon sink' effect. This shift in focus could change how scientists approach understanding and mitigating climate change.
A UK study found that common misconceptions about cat reproduction contribute to a significant number of accidental litters. The research reveals that nearly half of respondents believed female cats should have a litter before being neutered or were unsure.
A study published in Obesity found that healthcare costs rose gradually with each unit increase in BMI, starting above a BMI of 19. Researchers analyzed health insurance claims data from 17,703 Duke employees and observed higher medical costs for overweight and obese individuals.
A recent study published in the British Journal of Obstetrics and Gynaecology found that oral garlic did not provide significant relief for women with vaginal thrush. The research involved 63 women who took either garlic tablets or a placebo for two weeks, with no notable reduction in Candida levels observed.
Researchers identified a chromosomal deletion in the CFHR gene cluster, resulting in production of a hybrid CFHR2/CFRH5 that stabilized C3 convertase. Treatment with soluble C1 restored C3 convertase decay and may be a promising treatment option for patients with refractory dense deposit disease.
A study of over 4,400 physicians found that those who would personally enroll in hospice care are more likely to discuss it with patients, but delays remain. Despite personal preferences, many physicians do not have timely discussions about end-of-life care with terminally ill cancer patients.
Scientists from NTU have discovered a key process during the Malaria parasite's invasion of red blood cells and developed antibodies that can interfere with this process. This breakthrough has the potential to lead to the development of a low-cost vaccine that could save millions of lives.
A recent study found that metformin can lead to a modest reduction in body mass index (BMI) in obese children when used in conjunction with lifestyle changes. However, the benefits were relatively small and did not meet the desired threshold for long-term health benefits.
A new mouse strain has been developed to evaluate age-promoting compounds, including UV light and cigarette smoke. These findings demonstrate that UV light and cigarette smoke exposure increase p16INK4 expression, a key marker of aging.
Tinnitus affects millions of Americans, including veterans, and can be debilitating. Researchers at U-M have discovered a process called stimulus-timing dependent multisensory plasticity that is altered in animals with tinnitus. This finding provides a science-based approach to treating the condition.
Researchers at Tel Aviv University used fMRI to show that patients in a vegetative state can react emotionally to photographs of family and friends, suggesting they may be aware of their loved ones' presence. The study's findings provide hope for improved care and treatment for these patients.
Researchers at Imperial College London have devised a simple and reliable method to set sustainable hunting quotas for lions. The new algorithm estimates the number of adult males that can be hunted while allowing lion populations to grow, benefiting both conservation efforts and hunters.
Researchers found evidence of cat domestication in ancient China, tracing it back to farmers 5,300 years ago. The study analyzed bones from excavated sites and discovered that cats were attracted to rodents and other small animals in farming villages.
A new study finds that drought frequency is likely to increase globally by the end of the 21st century due to climate change. The research suggests an increase in global severity of hydrological drought, with greater increases if no mitigation policies are implemented.
The study emphasizes the need to consider human values in decision-making for long-term coral reef management. It highlights successful co-management arrangements in countries like Papua New Guinea and Kenya, where community engagement reduces conflict and increases ecological benefits.
The grant aims to build a more precise understanding of chronic traumatic encephalopathy and traumatic brain injury in civilians over age 45. Investigators will use extensive resources from an ongoing study of brain aging and conduct analyses of neuropsychology, neuroradiology, neurological, geriatric, and epidemiological aspects.
The US ethnic food market is dominated by Mexican cuisine, with over 7,000 restaurants across the country. Italian and Chinese cuisines are also extremely popular, with a large number of restaurants in major cities like New York and San Francisco.
Most multivitamin supplements have no benefit in preventing chronic disease or death, and long-term use does not preserve cognitive function. Researchers found that high doses of multivitamins and minerals do not protect against cardiovascular events following myocardial infarction.
The study reveals that theta-gamma oscillations in the hippocampus are generated by excitatory and inhibitory synaptic signals, which provide rhythmic signals for temporal coding. The researchers also found that granule cell neurons send signals only at specific times during the cycle of oscillations.
Researchers found that directly paying students to eat fruits and vegetables increases consumption by 80 percent, while also reducing food waste by 33 percent. This approach is cheaper and more effective than traditional school lunch rules, which often result in a significant amount of wasted produce.
Researchers evaluated 20 parenting programs and identified five that significantly reduce adolescent behavior problems, including substance use, aggression, depression, anxiety, and violence. These programs focus on fostering opportunities, skills, rewards for positive social behaviors, bonding, and clear expectations for behavior.
The study found that the Sunday Driver gene regulates myonuclear positioning and muscle function. Mutations in this gene lead to unevenly spaced nuclei and defective muscle contraction, indicating that mispositioned nuclei may be a possible cause, not consequence, of human congenital myopathies.
Death rates for lung cancer, colorectal, breast, and prostate cancers have been declining, driving a reduction in cancer deaths. However, some cancers, including liver and pancreas, saw increased death rates. Comorbid conditions also impact survival, with one-third of patients aged 65+ having multiple medical conditions.
Researchers discovered a 500-million-year-old chemical bond essential for animal life, which could lead to new cancer therapies. The sulfilimine bond is formed by hypohalous acids and is crucial for blood vessel formation.
A new study published in the Proceedings of the National Academy of Sciences finds that climate change will increase global water scarcity, affecting millions of people worldwide. The study estimates that 40% more people will be at risk of absolute water scarcity due to climate change, with significant regional differences in impacts.
A recent study published in Psychological Science found that Americans tend to overestimate the number of households struggling financially and underestimate those doing well. The researchers discovered that this perception was more pronounced among liberals, who believed the gap between rich and poor had grown significantly.
Researchers discovered that ATP-sensitive potassium channels in skeletal muscle play a crucial role in regulating energy consumption even during mundane activities. By modulating KATP channel activity, new strategies may be developed to combat metabolic disorders such as muscle wasting and obesity.
Rice University scientists have developed a spray-on coating made from graphene nanoribbons that can melt ice on sensitive radar domes without interfering with radio frequencies. The material is also transparent and durable, making it a promising competitor to existing deicing technologies.
Researchers discovered a genetic variation that predisposes mice to severe, inflammatory arthritis. The study implicates a lysosomal enzyme as a contributor to the development of the disease.
A phase 2 trial of a personalized vaccine made from patient tumor tissue showed improved survival rates compared to standard care alone. The vaccine, HSPPC-96, triggered an immune response to kill remaining tumor cells after surgery.
A recent study suggests that exposure to dust from homes with dogs can alter the immune response to allergens, reducing allergic inflammation. The researchers found that mice fed dog-associated dust were protected against airway inflammation triggered by cockroach allergen and respiratory syncytial virus.
A study published in the European Heart Journal found individuals with a family history of premature heart disease continue to have a higher risk of dying despite earlier referral to GPs, lifestyle changes, and drug treatments. Doctors are encouraging people to use Christmas gatherings to discuss their medical histories and reduce the ...
A recent study by Arizona State University researchers found that spaceflight alters the global gene expression of Candida albicans, a fungus commonly found in human bodies. The results indicate changes in cell aggregation, biofilm formation, and resistance to stress and antifungal drugs.