A new class of diabetes drugs has been linked to a doubling of the risk of pancreatitis in people taking them. Researchers found that patients who took glucagon-like peptide-1-based therapies were twice as likely to be hospitalized with acute pancreatitis as those on other medications.
The Cohen Veterans Center will conduct biomarker research to accurately diagnose post-traumatic stress disorder (PTSD) and traumatic brain injury (TBI), with potential treatments including targeted medications and therapies. The $17 million gift is believed to be the largest private donation to PTSD research.
Researchers developed a model that calculates how temperature changes affect parasite metabolism and life cycle, helping to predict disease ranges. The Princeton metabolic model can identify prospects for nearly any disease-causing parasite, even with limited knowledge of the organism.
Researchers at MIT have detected fluctuating charge-density waves in high-temperature superconductors, a key finding that could help understand the phenomenon and potentially lead to room-temperature superconductors. The new technique sheds light on the exotic state of matter, which has remained poorly understood despite intense research.
Adolescents who volunteered regularly for 10 weeks showed improved cardiovascular health by having lower levels of inflammation and cholesterol. The volunteers also experienced increased empathy, altruistic behavior, and mental health benefits, which contributed to their improved heart health.
Researchers will use a novel model and emerging technology to study astrocytes in autism spectrum disorders, providing a framework for future strategies. The grant supports Trapp's work on mechanisms of neurodegeneration and repair in multiple sclerosis and related conditions.
OHSU scientists have made a breakthrough by growing human liver stem cells in culture, demonstrating their therapeutic potential. The study's findings suggest that these cells can be infinitely expanded and converted into functional liver cells, offering new hope for treating chronic liver diseases.
Researchers found that prenatal DHA supplementation increased mean birth weight and gestational age, reducing the risk of very low birth weight and early preterm delivery. The study supports the use of dietary supplements during pregnancy to improve infant health outcomes.
A study led by Dr. Stephen Hwang of St. Michael's Hospital found that family physicians' offices in Toronto tend to give preference to patients with chronic health conditions and high socio-economic status. The researchers telephoned office staff playing the role of individuals seeking primary care, and observed a significant differenc...
A new study found that exposure to airborne dust in urban areas leads to an increase and decrease in childhood blood lead levels, respectively. The research suggests that focusing on primary prevention of lead-contaminated soils may be a more effective approach to improving child health than current efforts.
Researchers found that using the method-of-loci technique improved recalling positive memories for individuals with depression, potentially elevating their mood. The study suggests this memory strategy may be an effective tool in managing depression.
The EAU has made its patient information available in Spanish and Greek to cater to patients from diverse linguistic backgrounds. This move aims to provide trustworthy information on urological diseases to all European patients, with translations coordinated by national societies.
A new study from Karolinska Institutet reveals that cortisone increases the risk of acute pancreatitis. Patients treated with cortisone are recommended to avoid alcohol and smoking to minimize the risk. The study found a 70% higher risk of developing acute pancreatitis among those taking cortisone tablet form.
The US Preventive Services Task Force recommends against daily supplementation with vitamin D ≤ 400 IU and calcium ≤ 1,000 mg for fracture prevention in postmenopausal women. Daily supplementation has no net benefit and increases the risk of kidney stones, according to a systematic evidence review.
Research at Arizona State University has found that children with autism have higher levels of several toxic metals in their blood and urine compared to typical children. The study's findings suggest a strong association between toxic metal levels and variations in autism severity.
Two new species of Dianous and two new species of Stenus have been discovered in the Liupan Shan Natural Reserve. The beetles possess a unique ability to glide on water due to special gland secretions.
Scientists at Scripps Research Institute have found a telltale molecular marker for Onchocerciasis in patients' urine, detectable during active infections. The biomarker could form the basis of a non-invasive, portable test with significant advantages over current diagnostic methods.
A pilot study shows that qigong therapy significantly reduced cocaine cravings and depression symptoms in individuals undergoing residential substance abuse treatment. This promising treatment approach may have profound consequences in drug rehabilitation programs.
Researchers found that injecting NAC prior to harvesting significantly improves graft survival, with suboptimal organ usage showing higher benefits. The study suggests using NAC during organ procurement to reduce damage and improve transplant outcomes.
Researchers have discovered a 22-year record of atmospheric chemistry in Antarctic snow, revealing clear connections between oxygen anomalies and global El Nino events. This breakthrough enables the reconstruction of paleoclimate cycles, providing new insights into Earth's climate history.
A new study projects that most coral reefs will experience annual bleaching events by 2045, with a quarter experiencing them up to five years earlier. Reducing carbon emissions can delay these events in nearly a quarter of reef areas for over two decades.
Scientists at the University of Pennsylvania School of Medicine have discovered a way to repair lung damage caused by asthma and chronic obstructive pulmonary disease (COPD) by tweaking gene expression. They found that epigenetic regulators, including HDAC2, play a critical role in regulating lung development and regeneration.
A modified Newcastle disease virus has been developed to target prostate cancer cells without harming normal cells, offering a new treatment option for hormone-refractory patients. This oncolytic virus uses a retargeted design to minimize off-target losses and reduce the amount of virus needed for treatment.
A global survey reveals that environmental issues, particularly climate change, are a low priority for people in the US and around the world. In the surveys, the economy ranked highest in concern, with environmental issues ranking sixth.
Researchers found evidence of a previously unknown micro-continent, Mauritia, beneath the Indian Ocean using dating methods and plate tectonics analysis. The discovery suggests that such micro-continents may occur more frequently than previously thought and were carried by lava to their current location.
Researchers at UCSB create novel way to convert sunlight into energy using gold nanorods and platinum nanoparticles, avoiding common semiconductor material limitations. This new process shows promise for efficient and cost-effective solar power generation.
Scientists found that distinct niches exist in bone marrow to nurture different types of blood stem cells, which could improve the success of stem cell transplants and chemotherapy. The discovery suggests that targeting specific support cells may be therapeutic for treating certain cancers.
Researchers at MIT and Brookhaven Lab use ultrafast spectroscopy techniques to study electron waves in custom-grown materials. They discover that CDWs are an independent instability and likely competing with the HTS state, not its root cause.
USC scientists have developed an algorithm to predict the value of DNA sequencing, which could make it more affordable for clinics. The algorithm uses a model from ecology known as capture-recapture to estimate population sizes, with potential applications in public health, astronomy, and biology.
Babies born by C-section are five times more likely to develop allergies when exposed to common allergens. The study suggests that early childhood exposure to microorganisms affects the immune system's development and onset of allergies.
Researchers at the University of Oxford have identified a natural biological mechanism that allows brain cells to survive during a stroke, enabling the development of potential neuroprotective drugs. The 'endogenous neuroprotection' discovered in rats has shown to increase cell survival by stimulating production of hamartin protein.
Researchers at Karolinska Institutet have discovered a new pseudogene that regulates the tumour-suppressing PTEN gene, enabling its potential reversal. This finding could lead to more effective cancer treatments by reprogramming cancer cells and preventing resistance.
Researchers at UT Southwestern Medical Center have discovered an osteoblastic niche in the bone marrow that nurtures early lymphoid progenitors, specialized blood-forming cells responsible for producing T cells and B cells. This finding may lead to improved safety and effectiveness of bone-marrow transplants and treatments for illnesse...
A study published in Nature describes how the CPEB1 protein 'takes the brakes off' the production of proteins associated with cell proliferation and tumor progression. The mechanism, discovered using Hodgkin lymphoma cells, has been proposed as a general regulatory system that enhances cancer spread.
A new study suggests that achieving the UN's Sustainable Energy for All (SE4All) objectives by 2030 could significantly reduce greenhouse gas emissions and help limit global temperature rise to 2°C. The initiative includes providing universal access to modern energy, doubling renewable energy globally, and improving energy efficiency.
A new study reveals that pseudogenes can regulate cancer-related genes like PTEN, potentially leading to new treatments. The research found that pseudogenes sharing sequences with PTEN can control its activity in two ways.
Researchers at the University of Wisconsin-Madison have developed a new technique to accelerate protein analysis, allowing for the simultaneous identification of proteins in multiple samples. This breakthrough could lead to faster diagnosis of cancer and the discovery of novel drug targets.
Scientists at MBL have identified several genes linked to human neurological disorders, including Alzheimer's disease and Parkinson's disease, in the sea lamprey genome. The discovery will accelerate research on spinal cord injury recovery, as lampreys can regenerate their nervous system after injury.
Researchers at ICFO have discovered that graphene can convert a single photon into multiple excited electrons, generating larger electrical signals. This feature makes graphene an ideal building block for devices relying on converting light into electricity, with potential applications in solar cells and efficient light detection.
Researchers at the University of Bristol successfully implemented a full quantum circuit to calculate unknown eigenvalues using a quantum algorithm without prior knowledge. This achievement marks an important step towards practical quantum computing, enabling applications in quantum simulations and metrology.
Researchers found a once-a-month injection of omalizumab highly effective in treating teens and adults with chronic idiopathic urticaria. The treatment reduced symptoms by 53% after three months, offering a fast and safe alternative to antihistamines.
Researchers found that individuals with a smaller hippocampus are more vulnerable to stress and pain, leading to increased risk of chronic pain. Stress management techniques, such as relaxation and meditation, may help alleviate symptoms and prevent chronicity.
Researchers found abnormal brain activity in individuals with psychogenic disease, which is caused by emotional or mental stresses. The study suggests that understanding these underlying mechanisms could lead to better treatment options and improved patient outcomes.
A study by Henry Ford Hospital found that African-American children are more likely to develop food allergies than Caucasian children, particularly those with an allergic parent. The research suggests a possible genetic link, but further investigation is needed.
Researchers at the Zoological Society of London found that chimpanzees enjoy solving a challenging puzzle as much as humans do. The chimps used sticks to redirect red dice through pipes until they fell into an exit chamber, demonstrating their problem-solving skills and ability to experience satisfaction without food rewards.
Researchers at Georg-August-Universität Göttingen used parthenogenic stem cells to create cardiomyocytes and engineered heart muscle with normal properties. This breakthrough demonstrates the potential of parthenogenic stem cells for tissue engineering and could lead to new cell replacement therapies.
A WUSTL researcher has received a $2.25 million grant to create 3D computer models of brain biomechanics, which will help improve methods for preventing and treating traumatic brain injuries. The new models will provide a better understanding of what happens to the brain during such injuries.
Pulmonary fibrosis is a scarring of the lungs that causes shortness of breath and fatigue. Researchers identified a mechanosensitive cellular signaling pathway in myofibroblasts, which promotes survival and prevents normal cell disappearance after wound healing.
A Johns Hopkins research team has identified a protein called HIF-1α that helps cells slow down their growth in response to low oxygen levels. This process can potentially be used to treat diseases such as cancer and other conditions where cell growth is uncontrolled.
A new research project aims to develop sustainable air conditioning and refrigeration systems for vehicles, reducing fuel consumption and greenhouse gas emissions. The technology uses waste heat from engine exhaust to power the system, resulting in a significant reduction in emissions and energy consumption.
A new study found that young white males are more likely to commit suicide than other demographics among Army National Guard personnel. The researchers identified 17-24 year-olds as being 1.59 times more likely to have committed suicide, with males and white soldiers also facing higher risks.
A new climate model developed at NOAA's GFDL predicts an increase in snowfall for Earth's polar regions and highest altitudes, but a decline globally due to rising CO2 levels. This could spell trouble for regions relying on snowmelt as a source of fresh water.
Scientists successfully use parthenogenic stem cells to develop functional heart muscle and treat pulmonary fibrosis. Researchers find that inhibiting a protein called ROCK attenuates myofibroblast survival and prevents lung scarring.
Researchers identified diverse microbial communities in cattle manure, with some bacteria present in beef cattle not found in dairy cows. Diet and tillage management also affected pathogen transport in field runoff, highlighting the importance of soil management for food safety.
Researchers found that opponents of dam removal value aesthetics, cultural heritage, and recreational activities, while supporters prioritize ecological benefits and game fish restoration. Compromise solutions may be challenging due to differing ecosystem service values.
A recent study found that children of parents who didn't disclose their own drug use but delivered a strong antidrug message were more likely to exhibit antidrug attitudes. Parents should consider the potential unintended consequences of sharing their past substance use stories with their kids.
The European Space Agency's JUICE mission will observe ultraviolet emissions from Jupiter's system, providing insights into the composition of the icy moons' surfaces and atmospheres. The instrument will also map the moons' surfaces, sound their interiors, and determine their potential for supporting life in future manned missions.
Researchers have developed a method to measure nanoparticles as small as 1 nm in diameter using the Particle Size Magnifier (PSM) instrument. The study reveals that sulphuric acid, amines, and oxygenated organics are necessary for nanoparticle growth.
Researchers from KIT and the University of Toronto have successfully manufactured highly efficient light-emitting diodes using silicon nanocrystals. The SiLEDs can produce light in various colors and have a surprising long-term stability, making them an attractive alternative to existing LEDs.
The University of Calgary has launched a satellite to track near-Earth asteroids, enabling researchers to study these rare and difficult-to-detect objects. The NEOSSat satellite will enable scientists to take hundreds of sensitive images daily to search for moving dots of light that represent asteroids.