A new study suggests that vitamin D deficiency may play a role in the increased allergy and asthma risk in overweight and obese adolescents. Researchers found significant correlations between the severity of obesity, adipokine levels, and biochemical measures of allergic disease.
A new clinical trial shows that whole body vibration therapy increases bone-mineral density and muscle mass in adolescents with cerebral palsy, allowing for improved walking ability and overall health. The therapy significantly enhances leg and spine bone-mineral density, while also increasing muscle mass in the legs.
Researchers have found that bazedoxifene can stop the growth of breast cancer cells, including those with resistance to current targeted therapies. The study suggests that bazedoxifene's unique mechanism of action may make it a viable treatment option for patients with advanced breast cancer.
A new study found that participants who received the dietary supplement Juven experienced significant increases in lean body mass, while those who received a placebo did not. Blood concentrations of IGF-1 also increased among Juven recipients, but the correlation with improved muscle mass was not statistically significant.
Researchers discovered a molecular switch, Steroidogenic Factor 1, that stimulates steroid hormone production and cell multiplication in aggressive prostate cancers. This factor increases tumor growth and resistance to hormone treatment.
A study shows that bazedoxifene, an approved osteoporosis drug, inhibits estrogen-induced gene expression and cell proliferation in breast cancer cells. The medication also reduced estrogen activity and estrogen receptor levels in cultured human breast cancer cells.
A new study published by The Endocrine Society found that weight loss improves memory function in older, overweight women. After six months of dieting, their brain activity changed in the regions important for memory tasks, with improved performance and altered brain activity detected.
A pooled analysis of two clinical trials found that lorcaserin improves hemoglobin A1c levels and fasting blood sugar levels in nondiabetic, overweight patients. The study suggests that the drug's serotonin receptor activation may play a role in regulating glucose metabolism.
A new study in mice found that a high-fat diet in adolescence can lead to impaired spatial memory and learning in adulthood. The researchers also found long-lasting brain changes in the mice with memory deficits, including a partial loss of leptin, a hormone that supports cognitive function.
A new study presented at The Endocrine Society's Annual Meeting found that hormone treatment to halt puberty in transgender adolescents is effective and safe, relieving psychological suffering. After cross-sex hormone therapy, bone density caught up, similar to natural puberty, with no long-term harm detected.
Researchers have discovered that medications used to treat heart failure and high blood pressure can also aid in reducing obesity by preventing weight gain and increasing the production of energy-burning fat cells. The study found that these drugs helped increase brown fat cells, which burn energy to prevent weight gain.
A new study presented at The Endocrine Society's Annual Meeting found that excessive salt consumption is associated with a higher risk of nonvertebral fractures in postmenopausal women. Women who consumed the highest amount of sodium had more than four times the risk of fracture, even after adjusting for other factors.
Northern Australia is prone to bushfires during winter and spring due to dry conditions and strong winds. NASA's satellite images reveal active burning areas, highlighting the region's susceptibility to wildfires.
A new genetic test can accurately identify benign thyroid nodules in nearly all cases, potentially saving thousands of surgeries and eliminating the need for permanent hormone supplementation. This breakthrough test could have a major impact on healthcare costs and complications related to unnecessary medical procedures.
A study found that insufficient sleep raises levels of a substance in the body that controls pleasurable eating, leading to increased hunger and appetite. The research suggests that this may be due to an elevation in the endocannabinoid molecule 2-arachidonoylglycerol, which is involved in signaling rewarding events and enjoyment of food.
A new study finds that estrogen replacement therapy decreases anxiety symptoms in girls with anorexia nervosa, which may help prevent relapse. The treatment also appears to prevent worsening attitudes toward body image and food.
A recent clinical trial has found that impaired heart function among obese children and adolescents is associated with an increased risk of future heart disease. The study suggests that obese youth who exhibit insulin resistance and lower adiponectin levels are at higher risk for long-term heart disease.
A study published in PLOS ONE found that healthy, full-term babies secrete higher levels of corticosterone during labor and delivery compared to their mothers. Corticosterone concentrations increased with fetal distress and were linked to the method of delivery, with vaginally delivered infants producing more cortisol.
Researchers at Michigan State University developed comprehensive evolutionary case studies to improve student understanding of evolution. Students who grasped integrated scenarios performed better on tests about evolution in general, suggesting that this approach enhances overall knowledge.
A new observational study found that overweight and obese men secrete greater amounts of stress hormones after eating. Cortisol levels increased by 51% in the overweight group compared to 5% in the normal-weight group.
A new study has identified corticosterone as a potential biomarker of fetal stress during labor and delivery. Corticosterone concentrations increased by 148% compared to cortisol, suggesting that it may serve as an indicator of infant distress.