Researchers found a massive cone-shaped structure made of basalt stones weighing an estimated 60,000 tons, dating back to the early Bronze Age. The site is believed to be connected to ancient city of Beit Yerah and may provide insights into geological history.
The new SPECT/MR system offers exceptional molecular imaging capabilities, reducing patient exposure to ionizing radiation and offering customized multifunctional imaging. It has the potential to diversify options for clinicians and biomedical investigators, with possible human trials in the near future.
Studies reveal CO2 gas following seismic swarms, growth of Mount Everest, and remarkably modern Cretaceous seawater composition. Loess paleosol sequences in central Europe provide insights into the progressive evolution of a continental climate during the Middle Pleistocene.
A new method of dose calculation estimates radiation absorbed dose in radioimmunotherapy, predicting progression-free survival and enabling personalized treatment. Patients receiving higher doses (>200 centigray) had significantly longer progression-free survival.
Researchers at University of Southampton propose control system that stabilises environmental conditions when life is affected by and alters its environment. This mechanism has been neglected until now, but could be applicable to various real-world systems.
Outpatient treatment significantly reduces arrest rates for people with mental health problems, saving the government $95,000 per individual. Providing mental health care not only benefits individuals but also society as a whole.
A scientist suggests an alternative approach to calculating microbial growth thermodynamics, citing discrepancies between theoretical and experimental results. The Battley free energy equation offers a more realistic representation of real-world conditions.
A recent report by USDA Forest Service reveals a doubling of houses in dispersed rural settings and development on nonfederal resource lands over the past 30 years. The analysis showed that most new development was close to existing areas, with increases in housing similar across eastern and western Washington.
A new study finds that Transcendental Meditation improves graduation rates by 15%, with a greater impact on low-achieving students. The technique also reduces dropout rates and increases college acceptance.
Researchers at McGill University found that Leavenworthia plants regained self-pollen recognition function by taking over two other genes. This study suggests that the loss of complex traits may not always be irreversible in plants.
Researchers found that metabolic PET imaging detected coronary disease at an early stage, with a sensitivity of 96%, compared to 56% for MPI. This technique could potentially be used for initial CAD screening to help doctors better determine a patient's cardiac risk and manage care.
Researchers found that brain circuits controlling obsessive-compulsive behavior are intertwined with those controlling food intake and body weight. The study suggests that minor disruptions in this system may lead to disorders like anorexia nervosa or OCD, as well as obesity, where individuals overconsume high-fat foods.
The US Preventive Services Task Force found primary care interventions for preventing child maltreatment to be ineffective due to limited evidence. In contrast, diabetes patients on Medicare are two to three times more likely to use brand-name drugs than VA patients, at an added annual cost of $1 billion.
Researchers at the University of York have identified a key regulator gene called SPATULA that controls the expression of five other genes affecting seed germination. The study, using the model plant Arabidopsis, reveals how different varieties respond to environmental stimuli, which could lead to the development of better quality seed...
A recent study found that survivors of intimate partner violence are not receiving adequate mental health services, with most experiencing Posttraumatic Stress Disorder (PTSD) and/or depression. Despite having access to services, social stigmas, shame, and lack of information prevent many from seeking help.
The study analyzed patients with prior organ transplants and found that their outcomes after traumatic injury are not worse than those of non-transplanted patients. Transplanted organs were rarely injured in traumatic events, and immunosuppression may have played a role in protecting organs from inflammation.
A recent study found that approximately 40% of designated drivers have consumed alcohol, with many having blood alcohol levels that impair their driving skills. The researchers emphasize the importance of complete abstinence as a designated driver to ensure safety on the road.
Researchers found a unique arrangement of spin glass behavior in these new quasicrystals, which is distinct from the magnetic ordering seen in crystalline structures. The discovery provides insight into magnetism in complex environments and opens up new avenues for studying rare-earth quasicrystals.
Researchers at UNIST demonstrated a novel method for epitaxially synthesizing uniform and homogeneous III-V semiconductor nanowires on Si wafers. The high quality of the nanowires was achieved without using metal catalysts, opening up new possibilities for opto-electronic devices.
Researchers found hypometabolism in brain regions associated with Alzheimer's disease, even in cognitively normal subjects with amyloid plaque. This association suggests a potential early indicator of Alzheimer's disease before dementia sets in.
A study found that rod-shaped nanoparticles adhere effectively to endothelial cells, enhancing drug delivery. Researchers believe this technology holds promise for novel targeted therapies with fewer side effects.
A study of 783 older adults with diabetes found a two-fold increased risk for dementia among those experiencing hypoglycemia events. Clinically significant hypoglycemia was also associated with a greater risk for subsequent severe hypoglycemic events.
Scientists have discovered that knots tend to form at the ends of polymers, where they are frequent yet ephemeral. Once formed, knots move along the chain in a seemingly casual manner before disappearing or forming slip-knots/pseudo-knots at the center.
A UCLA study found that women with hyperemesis gravidarum (HG) who take antihistamines are more likely to experience bad outcomes, including low birth weight babies and premature births. The study also showed that these medications are not effective in treating HG symptoms
Researchers have discovered a tiny dwarf galaxy, Segue 2, with only 1,000 stars, offering insights into the formation of iron and other elements crucial for human life. The galaxy's size and weight are its most striking features, challenging astronomers' understanding of structure formation in the universe.
Researchers found hospitalization for severe hypoglycemia doubled dementia risk, while dementia patients experienced twice as likely severe hypoglycemic events. Cognitive impairment may lead to poor diabetes management and worse health.
A landmark study of the Swedish population found depression (32-fold risk for suicide), anxiety (15-fold risk), COPD (3.05-fold risk) and poor social networks to be significant risk factors. The study also showed that unemployment was a stronger social risk factor among women, while being single was a stronger risk factor among men.
Researchers at the University of Pittsburgh have developed a sensor technology that can detect and monitor diabetes through breath analysis alone. The sensor uses a combination of titanium dioxide and carbon nanotubes to measure acetone vapors in breath, offering a potential alternative to current blood glucose monitoring methods.
A new study suggests that long-term antidepressant treatment impairs fear extinction learning in rats, which may disrupt the effectiveness of exposure therapy. The authors propose a mechanism involving decreased NMDA receptor subunits in the amygdala.
A new study shows that split liver transplants can last just as long as whole organs in young children, potentially reducing waitlist mortality rates. The data from 2,679 pediatric patients who received liver transplants between 1995-2010 indicates improved safety of partial livers.
A US study found that reducing unnecessary and high-dose pediatric CT scans could lower the overall lifetime risk of future imaging-related cancers by 62 percent. The research suggests that eliminating unnecessary imaging and lowering doses for the highest-dose scans could prevent thousands of future cancers.
Researchers found that partial livers from deceased adult and teen donors have become less risky for infants, saving their lives. The study's findings suggest that the use of partial grafts from deceased donors has increased significantly over time, accounting for up to 32% of liver transplants in children.
Researchers found significant epigenetic changes in DNA methylation patterns related to immune function in people with and without schizophrenia. These changes were found to protect against delusion and hallucination symptoms in schizophrenia patients.
Researchers have identified a novel approach to moderate and severe pain therapy that could lead to lower dosage painkillers. The compounds bind to a separate site on the opioid receptor, potentially working with the body's own natural painkillers to manage pain.
Eve Marder's groundbreaking discoveries have fundamentally changed our understanding of how neural circuits operate and produce behavior. Her research on the stomatogastric ganglion has broad implications for studying neurological diseases like schizophrenia, depression, and chronic pain.
A study in Journal of Analytical Psychology reveals internal conflict between the left and right parts of the brain when triggered by 'hot button' words, affecting sense of self and external responses.
A new study suggests that universal HIV testing in India could be a cost-effective strategy to save millions of lives. The study found that testing every five years would be the most cost-effective option, with a price tag of $1,900 per year of life saved in the general population and $1,300 per YLS among high-risk groups.
Eve Marder's pioneering work in understanding the nervous system has helped redefine how we think about neurons and their capabilities. Her research using crustaceans has also shed light on conditions like depression, showing that imbalances in neuromodulation are key factors.
New research confirms the 'out of the tropics' model for tropical biodiversity, where most evolutionary lineages started in the tropics and expanded outward. Bridge species, which straddle the boundary between tropics and temperate regions, play a crucial role in this process.
Scientists at Kessler Foundation received grants to investigate emotional processing deficits in individuals with traumatic brain injury (TBI) and the effects of aerobic exercise on memory impairments. The studies aim to develop innovative rehabilitation interventions using objective data from brain imaging.
A comparative heart imaging study found that PET/MR measures up to PET/CT in cardiac applications, with comparable results for heart muscle viability assessment. The technology has implications for future studies into ischemic cardiomyopathy and arrhythmia development after cardiac arrest.
A new study published in Infection Control and Hospital Epidemiology reveals that small community hospitals experience a higher rate of ventilator-associated pneumonia than larger hospitals. The study found that patients on ventilators had long hospital stays and high mortality rates, suggesting that these under-resourced settings may ...
A new study reveals that hormonal treatment for endometrial cancer works by binding to stromal tissue cells, rather than directly targeting cancerous cells. Researchers hope to develop a simple test to determine patient suitability for progesterone therapy.
A meta-analysis of 71 studies found that agri-environment schemes, such as sowing wild-flowers and organic farming, enhance the diversity and abundance of wild bees, hoverflies, and butterflies. The results suggest that increasing flower abundance in field margins and roadsides can boost pollinator populations, especially common species.
A University of Florida study found that 35% of designated drivers had consumed alcohol and had blood-alcohol levels high enough to impair their driving. The researchers also discovered that most designated drivers were not always chosen by those who had previously driven sober, which is a concerning trend.
A new CU-Boulder study reveals a significant increase in dust emissions across the Western United States over the past 17 years. The research found that dust erosion is linked to an increase in calcium deposition in precipitation, with major increases observed in Colorado, Wyoming, and Utah.
Researchers used parallel PET/MR imaging to map chemotherapy distribution before surgery, improving risk stratification and patient management. This study suggests simultaneous PET/MR imaging can benefit patients by predicting cancer recurrence and avoiding unnecessary chemotherapy.
Researchers found a potential link between homocysteine levels and schizophrenia risk through epigenetic mechanisms. Elevated plasma homocysteine may contribute to gene expression changes that increase the likelihood of developing the disease.
A new study by Syracuse University researchers found that female Drosophila melanogaster flies actively influence sperm competition, allowing them to choose between different male sperm for fertilization. This discovery has major implications for the study of sexual selection and coevolution in animals.
A global assessment of genetically modified crops reveals why some pests have adapted to Bt proteins in a few years, while others resisted for over 15 years. The study found conditions favoring sustained efficacy include rare resistance genes and abundant refuges.
Researchers at Uni Basel have discovered Sox4 as a key player in cancer metastasis, triggering the epithelial-mesenchymal transition (EMT) process. The study found that Sox4 promotes the expression of genes involved in EMT and metastasis, leading to changes in gene expression and cell behavior.
A new hybrid molecular imaging system combines positron emission tomography and magnetic resonance to detect recurrent prostate cancer. The study reveals that PET/MR finds more areas of metastases than PET/CT, making it a viable alternative for restaging patients with metastatic prostate cancer.
Researchers at Rice University and Oak Ridge National Laboratory have advanced on the goal of two-dimensional electronics by controlling the growth of uniform atomic layers of molybdenum disulfide. The material is a semiconductor, one of three needed to make functioning 2-D electronic components.
A multi-institutional registry study involving 450 patients found that PRRT treatment significantly prolonged overall survival, with median progression-free survival of up to 51 months. Patients with pancreatic tumors survived an average of 39 months without disease progression.
Researchers have developed a fully integrated microfluidic test-bed to evaluate and optimize solar-driven electrochemical energy conversion systems. The system has been used to study schemes for photovoltaic electrolysis of water and can be adapted to study artificial photosynthesis and fuel cell technologies.
Researchers connect local consumption to global land use through tracking international trade flows, revealing a significant impact on developed countries' domestic resources. The study highlights the importance of developing economies like China and India in addressing environmental pressures.
A study led by St. Jude Children's Research Hospital found that epigenetic changes, such as cytosine methylation, are unique to each child with ALL and may be as important as genetic alterations in causing the disease. The research suggests that epigenetic targeted therapies could be developed for patients with ALL.
A nationwide study found Medicare beneficiaries are two to three times more likely to use brand-name drugs for diabetes and other conditions compared to VA patients. This difference in prescribing habits resulted in an estimated $1.4 billion savings in Medicare Part D spending if generic use matched the VA's approach.
Researchers found that sweets were 11.2% less available when both district and state limited sugar content, while regular-fat baked goods were less available with state law limiting fat content. The study concluded that governmental policies can be an effective tool in reducing empty calories in children's diets.
The study reveals HDAC3 plays a key role in regulating gene expression, chromatin structure, and genome stability. Disruption of HDAC3 expression leads to impaired hematopoiesis, highlighting its importance in stem cell functions and bone marrow failure syndromes.