The study found that patients with lower extremity joint replacement had the lowest hospital readmission rate (5.8%), while those with debility had the highest (18.8%). Higher motor and cognitive ratings were associated with lower readmission rates across all six categories.
Two approved weight-loss drugs have been linked to serious harms, including memory and depression problems, and cardiovascular risks. Researchers question the FDA's decision to approve these medications without more definitive evidence.
Researchers found that people attribute more status and competence to individuals who display nonconformity in prestigious contexts. This phenomenon, dubbed the 'Red Sneakers Effect,' suggests that intentionally deviating from norms can be a powerful signal of success.
Researchers at Max Planck Institute in Germany develop new way to measure electron pair emission directly on a standard lab bench using time-of-flight spectrometers. This breakthrough allows for the quantification of electron correlation strength, crucial for designing novel materials with desirable properties.
Researchers at the University of Chicago Press Journals found that controlling a chaotic environment may be key to helping people stop excessive behaviors like hoarding and stockpiling. Participants in cluttered rooms showed increased likelihood of impulse spending compared to those in organized spaces.
Researchers at UNC Lineberger Comprehensive Cancer Center found that bladder cancer subtypes are genetically similar to breast cancer subtypes. The study revealed two distinct genetic subtypes of invasive bladder cancer, basal-like and luminal, which share genetic similarities with breast cancer subtypes.
A study found that receiving two doses of the HPV vaccine significantly reduces the risk of genital warts and other STDs. The vaccine's efficacy was seen to decrease after three doses, but it still offers substantial protection against these diseases.
Scientists at WashU Medicine have developed a new approach to treating muscular dystrophy, using nanoparticles loaded with rapamycin to improve recycling of cellular waste. The treatment showed significant improvements in skeletal muscle strength and cardiac function in mice with Duchenne muscular dystrophy.
Researchers found that moderate aerobic exercise helps preserve retina structure and function after damage. Exercise was shown to have a direct effect on retinal health and vision, potentially leading to tailored exercise regimens or combination therapies for retinal degenerative diseases.
Between 2009-2012, 18 states introduced 36 bills modifying school immunization mandates, with the majority expanding exemptions. Most bills with administrative requirements restricted exemptions, but none were passed. The study highlights ongoing challenges in maintaining high immunization coverage.
Researchers have developed a new tracking system that takes 3-D movies of living sperm, providing detailed imaging and analyzing motility data. The method helps detect potential infertility-causing anomalies, such as bent tails, and may soon aid in vitro fertilization (IVF) clinics in selecting the most viable sperm cells.
Patients with Body Dysmorphic Disorder (BDD) reported significant improvements in symptoms and disability after receiving cognitive behavioral therapy. The study, published in Behavior Therapy, suggests that CBT is an effective treatment modality for BDD, offering a promising alternative to existing treatments.
Researchers use antisense oligonucleotides to skip over the mutated exon causing Huntington's disease, preventing formation of toxic protein fragments. The innovative therapeutic strategy is a proof-of-concept for treating complex diseases.
Researchers have discovered a new Burgess Shale fossil site in Kootenay National Park, which may be the world's most important animal fossil discovery in decades. The site has yielded over 50 animal species in just 15 days of field collecting, contributing to our understanding of early animal evolution during the Cambrian Period.
Recent decades have been the wettest in 3,500 years in North East Tibet, according to a new study. The region's tree ring records show wider growth rings, indicating moister growing conditions, with the last 50 years seeing increasing rainfall.
Researchers developed chemical agents that bind and potentially remove the anti-coagulant heparin, improving patient care. The system is biodegradable, reducing the risk of side effects.
Researchers at Penn Medicine developed a method to assess and diagnose psychosis in young children by analyzing cognitive development. The study found that children with psychotic symptoms had lower chronological ages than predicted, indicating a significant lag in cognitive development.
Researchers have identified the first structure of one of eight human amino acid transporters, known as HATs. This breakthrough provides new insights into their functions and opens up possibilities for developing drugs to tackle various diseases associated with HATs.
Researchers propose that a 33 A.D. Old Jerusalem earthquake triggered neutron radiation, causing the Shroud's distinctive image and potentially leading to incorrect radiocarbon dating results. The theory is based on piezonuclear fission reactions and suggests that neutron emissions from earthquakes could have imprinted the image onto t...
Researchers found that carvacrol can break down the outer coat of norovirus, making it more susceptible to other antimicrobials. This discovery could lead to the development of a new food sanitizer and surface sanitizer for settings where traditional bleach or alcohol-based cleaners are not effective.
A recent study published in PLOS Medicine suggests that type 2 diabetes may not be directly linked to substantial weight gain over time. Instead, researchers identified distinct patterns of obesity development, including stable overweight individuals and those who experience continuous weight gain before diagnosis. The findings highlig...
A study of 1,358 children found that preterm infants had higher plasma insulin levels at birth and in early childhood, indicating a potential link between preterm birth and insulin resistance. This association may suggest that preterm birth is a risk factor for the development of type 2 diabetes.
A €3.5m European Union-funded project aims to improve diagnosis and treatment of balance disorders through an online information system. The EMBalance tool will help clinicians accurately diagnose and manage balance-related conditions, reducing the risk of falls and improving patient independence.
A Michigan State University scholar found that Latino and black candidates won as often as their white counterparts when running for office. The study suggests that parties should recruit more minority candidates to address the lack of representation in elected offices
A new UK study found that targeting Twist, a nuclear protein accelerating epithelial-mesenchymal transition, may provide an effective approach for treating triple-negative breast cancer. The study showed that disrupting the interaction of Twist with BRD4 inhibited invasion and tumorigenicity in triple-negative breast cancer cells.
Dan Arvizu, NREL director, has been elected to the National Academy of Engineering for his leadership in the renewable and clean energy sectors. He was cited for promoting national balanced energy policies and making significant advancements in engineering education.
A 4-year follow-up study found that patients with acute kidney injury (AKI) in intensive care units who require renal replacement therapy do not benefit from higher-intensity treatment. Albuminuria was common among survivors, indicating ongoing risk of chronic kidney disease and mortality.
A new MIT robot developed by Hermano Igo Krebs can help pharmaceutical companies speed up drug development for stroke medications. By using the robot's measurements, companies may only need to test 240 patients to determine whether a drug works, reducing time and cost by 70%.
Scientists at the University of Freiburg have discovered a new paradigm for targeting specific cell types using nanoparticles. They developed particles that can recognize endothelial cells through biophysical principles, allowing for precise delivery to cancer cells without changing biological addresses. This breakthrough has significa...
A study of nearly 100,000 kidney donors found a small increased lifetime risk of developing end-stage renal disease following donation compared to healthy nondonors. The estimated cumulative incidence of ESRD at 15 years after donation was higher in donors than healthy nondonors, with blacks having the highest absolute risk.
Two solitary bee species use plastic materials to construct nests, replacing traditional plant-based building materials. The discovery suggests innovative use of common urban waste and potential benefits for parasite resistance.
The construction of an environmental data-logger using Arduino platform enables wider access to cutting-edge technology in biodiversity science. This innovation fosters new collaborations between electronics hobbyists and engineers with interest in biodiversity.
Researchers found that individuals who feel connected to a group are more likely to donate, even if it's for a different group. The study suggests that nonprofits can improve fundraising efforts by targeting specific demographics and avoiding comparisons between donors and recipients.
A new study found that children who grow up in well-managed households and have school engagement report fewer sexually transmitted diseases in young adulthood. The findings suggest that prevention programs should focus on family dynamics and youth development rather than just abstinence education.
A new imaging technique can diagnose aortic disease and predict potential complications in patients with bicuspid aortic valve. Blood flow changes were found to be driven by specific types of abnormal aortic valves, and the study demonstrated a direct association between blood flow patterns and aortic diseases.
A study by Penn microbiologists found that statins can lower cholesterol levels and make cells less susceptible to hantavirus infection. This could lead to potential treatments for the deadly virus, which causes flu-like symptoms and respiratory distress syndrome.
Researchers found that quitting smoking is associated with lower rates of mood/anxiety disorders and alcohol use disorder. The study analyzed data from over 4,800 daily smokers and found significant improvements in mental health outcomes after quitting or reducing cigarette smoking.
A study published in Molecular Biology and Evolution found that Tibetan Mastiffs have undergone genetic adaptations to survive at high altitudes. The research identified 16 genes involved in energy production critical for high-altitude survival, suggesting convergent evolution between dogs and humans.
A study by Johns Hopkins engineers used juggling to investigate how vision and the sense of touch help control limb movement, shedding light on potential treatments for neurological diseases. Adding haptic feedback improved performance, but didn't correct errors, highlighting the brain's reliance on timing information.
Researchers discovered that bacterial LPS components directly activate pain sensors, triggering immediate pain and inflammatory responses. This finding reveals a new target for drugs designed to treat bacterial infections, such as pneumonia and meningitis.
Researchers discovered that CB1 cannabinoid receptors control a circuit connecting the olfactory bulb to the olfactory cortex, increasing sensitivity to smell during hunger. This biological mechanism may be altered in obese or anorexic patients, enabling better management of these pathologies.
Researchers at Dana-Farber Cancer Institute found that the normal enzyme SYK pairs with mutated FLT3 to promote AML progression and resistance to treatment. Combination therapy involving SYK and FLT3 inhibitors showed significant promise in treating AML.
An international study found a strong association between household device ownership and increased rates of obesity and type 2 diabetes in lower and middle income countries. The prevalence of these conditions rose with the number of devices owned, highlighting the need for health interventions to mitigate the effects of modernization.
Researchers discovered that SPOP protein selectively destroys androgen receptor, a master regulator of prostate cancer cell growth. This finding sheds light on a new mechanism by which prostate cancer develops.
The FINNO Study found that women are more likely to suffer from incontinence, while men experience problems with slow or incomplete urination. The study also identified post-micturition dribble as the most common cause of bother among men.
A new micro-robotic technique allows for precise construction of individual cell-encapsulating hydrogels, enabling true control over bottom-up tissue engineering. This breakthrough has the potential to revolutionize 3D printing and tissue engineering, addressing organ shortages and improving disease treatment.
High pollutant concentrations in Guánica Bay's sediments pose a significant threat to coral reefs and marine life. The study provides an ecological baseline for improved watershed management.
A large-scale randomized control trial shows Schema Therapy to be significantly more effective than Clarification-Oriented Psychotherapy and treatment as usual in treating a range of personality disorders. The therapy resulted in higher recovery rates, greater declines in depression, and lower dropout rates.
A recent study found that six common species of fish near the equator are unable to survive in warmer waters, with some species experiencing a narrow temperature range. This suggests that climate change poses a significant threat to these fish populations, which could have devastating consequences for human societies reliant on them.
Johns Hopkins researchers identified a protein called SCAP that regulates fatty liver disease and diabetes. They found that SCAP's 'chauffeur' role is crucial to the cycle of fat production, and disrupting this process may lead to new treatments.
Tropical Cyclone Fobane, formerly known as Tropical Cyclone 14S, is weakening due to moderate to strong vertical wind shear and cooler waters. The TRMM satellite measured high rainfall rates near the storm's center, with rates of up to 35 mm/1.3 inches.
The University of Pittsburgh's Center for Medical Innovation has awarded funding to six research groups developing innovative biomedical technologies, including smart wound gels, point-of-care diagnostic instruments, and minimally-invasive brain surgery devices. These projects aim to improve healthcare outcomes and save lives.
Researchers used computer simulation to analyze X-ray crystallographic data and found that current software programs underestimate the level of dynamics in proteins. This could lead to more accurate pictures of protein structures and improved development of medicines.
New research finds that matchmaking brings intrinsic happiness to the matchmaker, particularly when pairing people who are less likely to meet. This study suggests that making meaningful connections is key to reaping emotional benefits from social interactions.
Micro-machining enables the creation of almost flat Fresnel lenses that significantly increase solar panel efficiency. The new design allows for a more precise focus of incident light, resulting in a four-fold increase in peak power compared to traditional panels.
A randomized controlled double-blinded trial involving 213 healthy women showed that the DIVA System provided better systolic blood pressure control and reduced nausea incidence compared to manual vasopressor administration. The system's enhanced speed and accuracy deliver a safer and better birth experience for patients.
Researchers have designed a system-on-chip that could enable fully implanted cochlear implants, restoring hearing in individuals with profound loss. The internal unit would be wirelessly rechargeable and require lower power sound processing.
Jayan Thomas is working on creating materials for a 360-degree 3D image without glasses. His research has led to a $400,000 NSF grant to develop display screens using nanotechnology.
Researchers at MIT determine the end-Permian extinction occurred over 60,000 years, killing 96% of marine species and 70% of life on land. The new timescale suggests massive volcanic eruptions from the Siberian Traps triggered a rapid collapse of global ecosystems.
A study by the University of Exeter reveals that crop pests are greatly underestimated in developing countries, posing a significant threat to global food security. With many nations underreporting pest loads, investment in pest observations is crucial to identifying and controlling losses.