A recent study analyzed 10 diverse citrus varieties and found very limited genetic diversity, which could threaten the crop's survival. The researchers hope to enable sequence-directed improvement to produce crops that better resist diseases and environmental changes through modern genomics-guided development.
Scientists at EPFL introduce a novel biosensor molecule that can quickly measure drug concentration in patients' systems using a digital camera. The method is simple, low-cost, and can be used by patients themselves.
Researchers at McGill University discovered a tiny molecule, miR-1202, that regulates glutamate receptors and is lower in the brains of depressed individuals. The study found that this microRNA increases with antidepressant treatment, suggesting it could be a potential target for developing new treatments.
Healthcare experts examine potential cost savings in maternal mortality reduction, adolescent cancer treatment, and biosimilar medication use. Studies reveal the importance of long-term financing plans and access to follow-up care for improved outcomes.
The common bean genome sequence reveals genes involved in critical traits such as size, flavor, and disease resistance. Identifying these genes will help researchers develop more nutritious and climate-resilient bean varieties.
A study by Weizmann Institute researchers found that human activities have altered the types of clouds over pristine ocean areas, leading to increased cloud height and rainfall. The team's model accurately predicted these changes using satellite images and aerosol data, suggesting a significant impact on global climate patterns.
Researchers have analyzed and compared the genomes of ten diverse citrus varieties, revealing that they originated from two wild citrus species diverged in Southeast Asia over five million years ago. The study provides valuable insights into disease resistance and breeding strategies for improving citrus yields.
Researchers at the University of Minnesota found that rats were willing to wait longer for certain flavors, indicating individual preferences. The study suggests that regret is a fundamental cognitive process shared among mammals.
The Phaseolus genome study provides valuable information on the genetic basis of nitrogen fixation in common beans, a crucial legume for agricultural sustainability. The research identified dense clusters of genes related to disease resistance and nitrogen metabolism, offering potential targets for future crop improvement efforts.
A study suggests that warming climates can indirectly increase CO2 levels in the atmosphere by reducing iron and silicon availability in ocean waters. This is particularly significant in the southern ocean and equatorial Pacific, which play a crucial role in regulating atmospheric CO2.
The researchers designed a nanoparticle with a peptide coating to target tumor cells, allowing for efficient drug delivery. The shell is etchable, enabling the removal of excess particles using biocompatible chemicals.
A new study confirms that children who live in homes with high levels of roach and mouse allergens and pollutants have higher overall allergy and asthma rates. However, those who encounter such substances before their first birthdays seem to benefit rather than suffer from them.
A clinical review published in JAMA explores the diagnosis and management of mixed urinary incontinence in women, a condition affecting 20-36% of women. High-quality evidence supports treating stress and urge urinary incontinences with surgery and medications respectively.
Researchers at Johannes Gutenberg University Mainz successfully measured the magnetic moment of a proton for the first time with unprecedented precision. The measurement has far exceeded previous attempts and will contribute to a better understanding of the matter/antimatter asymmetry in our universe.
A study published in Endocrine-Related Cancer has identified specific molecules in seminal fluid that can detect prostate cancer and predict its severity. The presence of these microRNAs, particularly miR-200b, shows promise as a prognostic tool for indicating treatment urgency and type.
A new study published in the Journal of Allergy and Clinical Immunology found that infants exposed to a diverse range of bacterial species in house dust during the first year of life are less likely to develop asthma in early childhood. The study, led by UCSF researchers, suggests that immune responses may be shaped by exposures during...
Researchers have identified a protein that regulates calcium levels in cells, which could be a promising strategy for fighting cancers. The study reveals how this protein serves as a molecular safety valve to maintain steady calcium levels.
Researchers have uncovered three gene networks in autism that could lead to new treatments for attention-deficit hyperactivity disorder (ADHD) and schizophrenia. The networks, which affect neurotransmitter signaling, may also provide insights into the biological mechanisms underlying autism.
Researchers discovered that certain blockages in fruit fly brains quickly resolve themselves, suggesting a distinction between benign and permanent blocks. This study could help scientists identify and treat neurodegenerative diseases by focusing on permanent blockages.
Researchers bridge the size gap to study kinetic behavior of Ag nanocatalysts using SERS, providing real-time reaction information. The stepped surface of etched nanoparticles mimics sub-5-nm environment, increasing active surface atoms' participation in catalysis.
A University of Rochester research team has created a technique that keeps stem cells in place, resulting in faster and better tissue regeneration. The key is encasing the stem cells in polymers that attract water and disappear when their work is done.
Physicists confirm existence of exotic dibaryon made up of six quarks, a complex particle that could open door to new physical phenomena. The discovery was made using the WASA-at-COSY collaboration and has been published in Physical Review Letters.
Researchers at the University of Akron have developed a shatterproof screen technology using a transparent electrode that is tough, flexible and cost-effective. The new film can withstand repeated scotch tape peeling and bending tests, offering a potential replacement for traditional touchscreen displays.
A new study found that health policy researchers are hesitant to use social media due to concerns about being perceived as 'opinion' or presenting scientific results in a superficial manner. However, when provided with examples of effective use, researchers became more confident in utilizing social media channels.
A NIH-funded study found that early life exposure to specific combinations of allergens and bacteria protects against wheezing and allergic disease. The Urban Environment and Childhood Asthma (URECA) study revealed that cockroach, mouse, and cat exposure during the first year of life is associated with a lower risk of recurrent wheezing.
The study provides a new framework to interpret previous research on European Neolithic populations, suggesting that the expansion took place through pioneer seafaring colonization. Genetic affinities between the mitochondrial DNA of first Neolithic farmers and those of Catalan and German farmers support this hypothesis.
Researchers have found evidence of an intercellular bacterial infection in natural populations of two species of Anopheles mosquitoes, a major vector of malaria. The Wolbachia infection has been shown to reduce the incidence of pathogen infections in mosquitoes and could be used to control malaria-transmitting mosquito populations.
A team of biologists at the University of Leicester has discovered a pair of proteins called DAZ1 and DAZ2 that are essential for making twin sperm cells in plants. The study reveals how these proteins work together with a 'master switch' protein DUO1 to control a gene network that ensures a pair of fertile sperm is produced.
The Netherlands Organization for Scientific Research (NWO) has awarded the NWO Spinoza Prize to four outstanding researchers: Dirk Bouwmeester, Corinne Hofman, Mark van Loosdrecht, and Theunis Piersma. They will receive 2.5 million euros to pursue their research in various fields of science.
A new study published in Clinical Gastroenterology and Hepatology found that probiotics can modify the gut microbiota to prevent hepatic encephalopathy in patients with cirrhosis of the liver. The researchers discovered that probiotic supplementation was not associated with any side effects, suggesting a safer treatment option.
Scientists have identified four microRNAs that can aid in the differential diagnosis of malignant pleural mesothelioma (MPM) from non-cancerous pleural tissue. The biomarkers, miR-126, miR-143, miR-145, and miR-652, were found to classify tissue samples with high accuracy.
Untrained elderly men achieved marked improvements in maximum oxygen uptake, muscle function, and bone mineralization after playing football for four months. The study shows that intense football training can change the lives of elderly men, making it easier to live an active life and overcome physical challenges.
Researchers used in situ TEM to study the evolution of platinum/cobalt nanoparticles during reactions in oxygen and hydrogen gases. They found that cobalt atoms migrate to form a cobalt oxide epitaxial film, which affects catalytic performance.
A tropical low pressure area in the Bay of Campeche is showing signs of development, with cloud-top temperatures near -63F (-52C). The system has a 50% chance for formation, threatening southeastern Mexico with heavy rains and life-threatening flash floods.
A large Canadian study of over 8,500 patients found a significant link between obstructive sleep apnea and the development of diabetes. The study confirmed earlier evidence and identified that initial severity of OSA predicted subsequent risk for incident diabetes.
Researchers at Mayo Clinic have developed an optical blood oxygen sensor attached to an endoscope that can identify pancreatic cancer with a sensitivity of 92% and specificity of 86%. The device measures changes in blood flow near the pancreas, which tumors alter to grow. Early detection is crucial as most pancreatic cancers are diagno...
International team discovers seven new species of giant pill-millipedes with largest chirping organs, found in rainforests and isolated forest fragments. Conservation efforts needed to protect these microendemic species due to impending mining projects.
Researchers create systematic map of pain acuity distribution across body, revealing surprising similarities with touch sensitivity. The study uses lasers to cause pain in healthy volunteers and a rare patient lacking touch sensation, demonstrating that pain acuity does not rely on touch.
A recent study by San Francisco State University's Jeff Cookston found that adolescents receiving a reason for their father's behavior or a better understanding of who is at fault feel better about themselves and dad. This, in turn, is linked to a lower risk of depression for youth.
Researchers from the University of York have provided new information on how LPMOs work, enabling the degradation of hard-to-digest biomass into its constituent sugars. This breakthrough aims to improve second-generation biofuel production by fermenting cellulose into bioethanol.
Researchers from GFZ, University of Sydney, and University of London discovered that the centre of a rift migrates laterally during continental break-up, causing asymmetry in continental margins. This process leads to the formation of thin crustal slivers on one side and more pronounced asymmetry due to faster extension velocity.
A new study found a significant decline in speeding-related injuries and fatalities among young men in Ontario since the province's tough laws were introduced in 2007. The study credits the deterrence of swift and severe sanctions for reducing risky driving behavior.
Researchers from the University of Freiburg have made significant progress in understanding how the antimalarial drug atovaquone works. By analyzing its molecular structure, they have identified key binding sites and revealed the underlying mechanism of resistance to mutations. This breakthrough could lead to the development of more ef...
A recent study published in the American Journal of Preventive Medicine found that a text-messaging program helped over 11% of smokers quit smoking compared to just 5% of controls. The program provided personalized advice and reminders to help smokers stay on track with their quitting efforts.
Scientists at HZI have shown that herpesviruses like KSHV and MHV68 modulate the TLR-induced proinflammatory cytokine response, allowing them to remain within the body for a long time. The researchers discovered that the virus actively prevents activation of the innate immune system through Toll-like receptors.
Reducing tropical deforestation significantly reduces carbon dioxide emissions by up to one-fifth. Tropical forests absorb almost two billion tonnes of carbon annually, but human activities like logging and biofuel production lead to equivalent losses.
Researchers found three diseases have failed to receive official recognition and funding, impacting human and animal health in developing nations. A multidisciplinary One Health approach could improve human and animal health and control these diseases.
Scientists from MIPT, RAS, Kurchatov Institute and Kintech Lab Ltd have developed a new method to synthesize nickel-carbon compounds using electron irradiation. The study reveals potential electronic, magnetic and optic features of these compounds.
A new study finds that grey squirrels' genetic diversity directly impacts their ability to invade and spread across European environments. The research reveals that small founding population sizes result in reduced genetic diversity, hindering the squirrels' capacity for invasion.
Amunix is presenting unpublished data on its XTEN half-life extension technology, which extends the half-life of biologically active molecules via chemical conjugation. The technology has been used to extend the half-life of genetically fused therapeutic proteins and peptides.
Researchers at Whitehead Institute have identified a critical weakness in metastatic cancer cells, which are resistant to current anticancer drugs. The compound targets the endoplasmic reticulum of these cells, causing them to die.
Researchers at McLean Hospital have found that transplanted fetal dopamine cells can remain healthy and functional for up to 14 years in patients with Parkinson's disease. The discovery could lead to new therapies using stem cells grown in labs, reducing symptoms and the need for dopamine replacement drugs.
Researchers at Rice University have developed a nucleic acid-based test to detect signs of HIV and track viral loads in patients in low-resource settings. The new test, called qRPA, uses recombinase polymerase amplification and can be performed at the site of care, eliminating the need for complex lab equipment.
Researchers have successfully scaled up molecular self-assembly from nanometers to millimeters using noncovalent interactions, enabling the creation of large-area nanostructures. This breakthrough paves the way for alternative patterning techniques in nanoelectronics and materials science.
Bromine is the 28th element essential for tissue development in all animals. Fruit flies died without bromine but survived with its restoration. This finding has implications for human diseases such as kidney function and dialysis patients.
A mouse model of endometriosis has been developed that produces lesions similar to those found in humans. The study suggests that macrophages present in shed endometrium contribute to the development of endometriotic lesions, providing new insights into the disease.
Researchers found that bumblebees can differentiate between rewarding and aversive artificial flowers based on their polarization patterns. The bees' ability to recognize these patterns helps them identify suitable flowers for obtaining a food reward.
Researchers at Rice University have developed customized carbon nanotubes that can deliver chemotherapy agents to pancreatic cancer cells. The nanotubes are small enough to pass through the pores of cancer-related blood vessels, allowing them to target and infiltrate the nuclei of cancerous cells.
Researchers found that sleep after learning encourages the growth of dendritic spines in mice, which helps consolidate and strengthen new memories. The activity of brain cells during deep sleep is critical for this process, suggesting a physical mechanism for how sleep enhances memory formation.
Transplanted dopamine neurons from fetal tissue remain healthy for at least 14 years after transplantation, according to a recent study. The findings suggest that stem cells can be a viable source for transplant-ready dopamine neurons, providing further rationale for pursuing this therapeutic approach.