A new centre, The Oxford Centre for Drug Delivery Devices (OxCD3), will be established to exploit engineering approaches to improve the therapeutic outcomes of drug-based cancer treatments. The centre aims to use stimulus-responsive nanocarriers and medical devices to enhance drug delivery into tumours.
A new review highlights the need for healthcare professionals to be aware of rare causes of headaches in pregnancy, including conditions like idiopathic intracranial hypertension and cerebral venous thrombosis. These conditions can be fatal if not treated promptly and require prompt medical attention.
A new concept for counter-rotating wind turbines in tandem arrangements has been developed to improve power production performance. Experimental studies have shown that this configuration can increase energy utilization by up to 20%, particularly beneficial for onshore wind farms with smaller spacing between turbines.
Researchers at the University of Southampton are using fruit flies to study the internal circadian rhythms that control sleep, blood pressure, and metabolic rate. The findings could provide valuable insights into medical conditions and even help understand jet lag and temperature response mechanisms.
A University of Alberta researcher has developed a paper-based diagnostic tool to detect deadly food-borne pathogens such as E. coli. The device, slightly larger than a postage stamp, is designed to be extremely portable and self-contained, allowing for daily testing on farms in developing countries.
The Slide Fire has burned 7,500 acres in Oak Creek Canyon, threatening 300 structures, including private homes and a Forest Service lookout tower. Over 840 personnel are fighting the fire, which is 5% contained, with crews conducting burnout operations along the north and east flanks.
Drones have been developed with flight control mechanisms inspired by birds, bats, insects, and snakes to navigate through urban environments. Researchers have made significant advancements in drone technology, enabling them to perform complex tasks such as obstacle avoidance, pick-up and delivery, and landing on tricky surfaces.
Researchers found that people's private opinions are influenced by group norms, but this effect only lasts for three days. The study controlled for methodological issues and suggests a neurological explanation for the short-lived impact of social influence.
Researchers at SLU's Institute for Molecular Virology have discovered a small fragment of adenovirus that can repress HER2 cell growth and kill breast cancer cells. The discovery offers a promising new therapy for the deadly disease, which affects 20-30% of breast cancers.
Researchers at KU Leuven found that the Pyrenean rocket, a plant from southern Europe, genetically adapted rapidly to its new environment in Belgium, allowing it to spread quickly. This study provides evidence that rapid evolution can aid the spread of non-native plant species.
Researchers at MIT have developed a method to produce graphene directly on materials like large sheets of glass, enabling scalable manufacturing. This breakthrough could lead to advances in display screens, solar cells, and other electronic devices.
A study by Ecological Society of America finds that excluding invasive pests like the emerald ash borer from imported goods saves US $11.7 billion, outweighing added costs. The treatment reduces wood borer infestation rates by up to 52%, benefiting homeowners and local governments.
A brain imaging study reveals differences in basal ganglia activity and similarity to inflammation-induced fatigue in chronic fatigue syndrome. Reduced basal ganglia activity is associated with the severity of fatigue symptoms.
Researchers at Norwich BioScience Institutes have found ways to improve the efficiency of turning straw into biofuel. By varying pre-treatment stages, they increased cellulose conversion and sugar yield.
Researchers successfully trapped and controlled light using graphene-based optical antennas, demonstrating the fundamental principles of conventional optics. The discovery paves the way for the development of compact and faster photonic devices and circuits, which could revolutionize signal processing and computing.
Researchers discovered that pigs from infected mothers suffer less from the infection than those from non-infected mothers. The study found that maternal antibodies in the sow's milk protect piglets from infections in the first few weeks of life, leading to fewer cases of severe diarrhoea and faster recovery.
Researchers have developed a new method for creating Janus and patchy capsules using electro-coalescence and electro-hydrodynamic flow. These capsules can be used to transport substances and release them in specific environments, making them useful for biomedical applications.
Dr. Ekaterina Dobryakova, a postdoctoral fellow at Kessler Foundation, received an award to study motivation's influence on cognitive fatigue in patients with multiple sclerosis (MS). The research aims to determine whether motivation activates brain regions thought to be impaired in cognitive fatigue.
Researchers develop a new framework for risk assessment that incorporates sociological perspective and human risk perception, leading to more effective mitigation plans. The framework helps decision-makers understand public perception of natural hazards, resulting in better policy decisions.
A new multispectral light sensor can detect ultra-violet to near infrared light, enabling non-invasive medical procedures like oxygen level measurement and tumor detection. The sensor's low cost and flexibility make it suitable for various applications, including security cameras and consumer products.
A new approach enables researchers to distinguish between different microbial species in complex communities, allowing for the discovery of previously unknown species and a better understanding of their genomic content. This breakthrough has significant implications for studying the human microbiome and its impact on individual health.
Researchers believe a high-velocity hydrogen cloud, known as the Smith Cloud, contains and is wrapped in a substantial halo of dark matter, allowing it to survive a collision with the Milky Way. The discovery could provide insights into the formation of galaxies and the earliest star formation in our galaxy.
A phase I study found that alisertib inhibited aurora A kinase, a target for aggressive lymphoma treatment, in about one-third of patients with non-Hodgkin lymphoma and chronic lymphocytic leukemia. The oral drug showed manageable side effects, paving the way for advanced trials.
A recent study published in Urban Ecosystems found that a lack of plant diversity is a significant contributor to the widespread defoliation caused by cankerworms in cities. Increasing plant diversity can help limit future damage. Native plants were particularly hard hit, while nonnative species were largely ignored.
The National Hurricane Center expects TD1E to strengthen into a tropical storm later today. The depression has maximum sustained winds increasing to 35 mph (55 kph) and is moving west-northwest at 5 mph (7 kph).
Researchers at UT Southwestern Medical Center discovered a critical role for microRNA cluster miR-143 and miR-145 in regulating wound healing in the intestine, which may lead to potential treatments for chronic digestive diseases like ulcerative colitis and Crohn's disease.
Tropical System 92B has weakened due to persistent easterly vertical wind shear, according to NASA's infrared data. The Joint Typhoon Warning Center downgraded the potential for significant tropical cyclone development within the next 24 hours to medium.
Research by Chong Oh found that Twitter activity has a direct positive effect on movie attendance and online word-of-mouth chatter. Engaging with followers on social media increases the likelihood of higher box office performance.
Researchers have discovered a common rulebook for the immune system's T cells, enabling faster identification of antigens and potential treatments. This breakthrough could lead to improved understanding of autoimmune diseases like diabetes and multiple sclerosis.
Researchers develop protocol combining hard X-ray tomography and histology to visualize constricted vessels, enabling simulation of blood flow and targeted drug delivery. The method also characterizes soft tissues in the vicinity of calcified arteries with high precision.
A study by the University of Adelaide found that women who eat a poor diet before becoming pregnant are around 50% more likely to have a preterm birth than those on a healthy diet. Women who consistently ate high protein and fruit prior to conception were less likely to have a preterm birth.
Amanda strengthened into a tropical storm on May 23 with maximum sustained winds of 40 mph. The storm is expected to remain in weak steering flow and maintain its current trajectory.
Researchers at Brown University discovered that tiny muscles called plagiopatagiales embedded in a bat's wing membrane can adjust stiffness and curvature during flight, fine-tuning aerodynamic performance. The muscles tense on the downstroke and relax on the upstroke, working in synchrony to stiffen the wing.
Researchers at Yale Cancer Center presented findings from the 50th Annual Meeting of ASCO, highlighting the effectiveness of nivolumab and ipilimumab in treating advanced melanoma. Additionally, studies showed that lifestyle changes such as healthy eating and regular exercise can decrease biomarkers related to breast cancer recurrence ...