A new tick-borne bacterium, Neoehrlichia, has been linked to six cases of disease in Sweden, posing a significant risk to people with weakened immune systems. Researchers found that those over 50 years old with haematological or rheumatic diseases undergoing immunosuppressive treatment are most vulnerable.
Paul Glasziou argues that open access models can reduce research waste and improve the quality of medical research. He suggests that charities and governments should publish funded work in open access to make it more effective, as $100 billion of pre- and post-publication research is wasted annually.
A study found that observing e-cigarette use increases young adult smokers' desire to smoke both combustible and e-cigarettes. The study suggests a need for policy attention on the secondary effects of e-cigarette use on observers.
Researchers found that health issues and relationship changes have a major effect on the economic well-being of low-income rural families. However, social support networks, usually extended family, can help mitigate hardship by providing emotional and financial support.
A team of scientists reveals that a specific protein recognizes and repairs DNA crosslinks using the Fanconi anemia signal pathway. The study sheds light on the complex process of repairing damaged DNA, which can trigger cancer development. This new knowledge may lead to improved drugs for cancer treatment.
Researchers tracked two consecutive years of zebra migrations between Chobe River in Namibia and Nxai Pan National Park in Botswana, covering a straight-line distance of 250km (500km round-trip). The findings highlight the importance of trans-frontier conservation areas in preserving great terrestrial migrations.
Pharmacists at Jena University have developed three potential therapeutic agents that may improve the healing of inflammatory illnesses. The agents suppress a key enzyme in the body's own cascade of inflammation, specifically targeting 5-LOX, which plays a pivotal role in synthesizing leukotrienes. This breakthrough could lead to more ...
An analysis of 600 American College of Cardiology/American Heart Association guideline recommendations found that 80% were retained at the next revision, while those not supported by multiple randomized studies were more likely to be downgraded. The study suggests the need for frequent re-evaluation of practices and policies based on g...
The Funny River Fire in southern Alaska has been reported as 30% contained, affecting 158,585 acres. The fire is spreading northeast towards Skilak Lake Road, prompting evacuations and closures along the Kenai River.
Tropical forest carbon accumulation is reduced by nearly 20% due to invasive vines. Lianas block sunlight for tree growth and don't compensate for displaced carbon.
Research by Stan Floresco reveals the dynamic competition between brain regions to inform decisions. The frontal lobes temper impulses towards larger, uncertain rewards, while dopamine neurons provide short-term updates on recent outcomes.
Researchers have unveiled a new method for controlling the growth of metal-crystals from single atoms, enabling precise components for nanotechnology. The breakthrough, called Nanocrystallometry, allows for the creation of ultra-precise metal-crystals with potential applications in electronics, sensing, and energy storage.
Researchers found that bioelectrical signals from distant cells can control tumor formation, with a common fatty acid produced by bacteria playing a key role. This discovery opens up possibilities for preventing, detecting, and treating cancer.
Researchers found a genetic variant in noncoding DNA that leads to protein overproduction in heart cells, increasing the risk of sudden cardiac death by 40%. The discovery could lead to new drug treatments and improve understanding of cardiac repolarization.
A policy of higher NHS spending in deprived areas is associated with a reduction in absolute health inequalities from causes amenable to healthcare. This trend continues even after adjusting for other factors, suggesting that targeting resources at deprived areas may be an effective strategy.
A new study has shed light on the role of dopamine-dependent reinforcement signals in the nucleus accumbens, a region connected to pleasure seeking and drug addiction. The research, using optogenetics, reveals how glutamate-dependent signals from other brain regions interact with these signals.
Researchers have developed a new treatment for drug-resistant epilepsy that suppresses seizures 'on demand' with a pill, similar to painkillers. The treatment uses genetic modification of brain cells to make them sensitive to a normally inactive compound, avoiding side effects and permanent brain alterations.
Researchers have developed a new nickel catalyst that catalyzes the cross-coupling reaction between carbonyl compounds and phenol derivatives to form alpha-arylketones, which are found in many biologically active compounds. The study has potential applications in synthesizing biologically active molecules and organic materials.
A daily 20-minute walk can significantly reduce the risk of mobility disability in older adults, with a 18% reduction observed in participants who engaged in physical activity. The Lifestyle Interventions and Independence for Elders (LIFE) Study found that maintaining mobility is key to functioning independently.
A Baylor University study found that corporate communicators can effectively influence senior business executives by building informal coalitions in various settings, including coffee shops. This approach bridges gaps between rank-and-file employees and executives, helping companies avoid mistakes and protect reputations.
A school-based intervention aimed at increasing physical activity, reducing sedentary behavior, and improving fruit and vegetable consumption among children showed no significant effect. However, the program did reduce weekend screen time and snack consumption in children.
Researchers have found that disturbed blood flow leads to epigenetic changes in genes lining blood vessels, contributing to atherosclerosis. The study suggests that good blood flow patterns can persist over time due to these lasting changes.
Researchers have developed a new imaging technique using X-ray dark-field radiography to detect lung diseases at an earlier stage. This method provides detailed images of soft tissue, enabling the visualization of structural changes in lung tissue.
The GME system faces transparency and accountability issues, with only 20.9% of residents practicing primary care. Recommendations propose fully funding the National Health Care Workforce Commission and requiring transparent spending of GME funds to support a more efficient physician workforce.
The Panama government has implemented new traffic separation schemes to minimize overlap between commercial vessels and humpback whale migration routes. The changes are expected to reduce vessel speed four months a year and minimize vessel-whale collisions by up to 95%.
A 12-week clinical trial found that drinking diet beverages helped participants lose 44% more weight than those consuming water alone. Participants in the diet beverage group reported feeling less hungry and experienced improvements in cholesterol levels.
Researchers found a striking lack of diversity in the earliest known fossil bird fauna, with larger birds and water birds missing from the sample. The scientists applied a statistical technique to modern-day birds to relate physical characteristics to behavior, diet, and habitat.
Researchers at Georgia Institute of Technology and Emory University discovered that altered blood flow induces epigenetic alterations in endothelial cells, leading to atherosclerosis. Additionally, they found that reduced expression of the aldehyde dehydrogenase 1 enzyme makes dopaminergic neurons more susceptible to degeneration in Pa...
A study by researchers from the University of Montana finds that climate warming is increasing hybridization between native westslope cutthroat trout and invasive rainbow trout. This accelerated hybridization threatens the genetic integrity and diversity of native species.
A Penn Medicine research team found that recommendations supported by multiple randomized controlled trials were the most durable and least likely to change over time. The study analyzed over 600 Class I ACC/AHA recommendations, finding that 4 out of 5 remained valid across two guideline editions.
Researchers analyzed nearly 3,000 cod bones from 95 excavations in and around London, identifying a sudden change in the origin of the fish during the early 13th century. This shift indicates the onset of a large-scale import trade, revolutionizing the local fishing industry.
A study compared phenolic compounds in indigenous rose species to those of modern cultivars, revealing distinct differences in leaf phenolic content. Indigenous rose species are found to contain higher levels of phenolic antioxidants, making them a potentially suitable source for medicinal purposes.
A new Vanderbilt University study found that women with blood in their urine were less likely to be referred to a urologist for further tests than men with the same issue. The disparity may contribute to delayed diagnoses and worse mortality rates among women with bladder cancer.
Researchers found exercise training significantly reduces HSP90 overexpression in PD rats, suggesting a potential therapeutic target for skeletal muscle abnormalities. This study supports the use of HSP90 inhibitors as a new treatment option for PD-related muscle issues.
Smaller laser-plasma accelerators could accelerate particles to high energies, potentially reducing the cost of high-energy physics research and industrial applications. The new technology uses a combination of lasers to create an incoherent wakefield, which would allow for more sustainable and affordable accelerators.
Researchers found that stiff arteries alone can lead to high blood pressure by preventing the body from sensing changes in blood pressure. This discovery could pave the way for new treatments targeting arterial stiffness as a key factor in developing high blood pressure.
New analysis of Moon rocks indicates regional variations in water content, providing insights into lunar formation and crust cooling processes. The study suggests that the Moon's water may have originated from both Earth and comets/asteroids, with implications for understanding the source of Earth's water.
Researchers found that better access to healthcare can offset the natural decrease in mammogram use as a woman's life expectancy grows smaller. Women with limited life expectancy who live in areas with greater access to healthcare are more likely to be screened for mammograms.
Researchers at McGill University discovered that melatonin supplements increase bone volume and density in elderly rats, making them stronger. This finding suggests that melatonin may be a useful tool in combating osteoporosis.
Researchers at Children's Hospital Los Angeles found that infants treated with inhaled hypertonic saline had lower rates of hospital admission compared to those receiving normal saline for bronchiolitis. The study, published in JAMA Pediatrics, suggests a promising and inexpensive treatment option to reduce healthcare costs.
Scientists at TUM successfully demonstrated brain-controlled flight with high precision, exceeding requirements for a flying license test. They achieved this by using electroencephalography to convert brain waves into control commands, allowing pilots to control the plane without touching pedals or controls.
A team of scientists has successfully created a triple twisted Möbius annulene, a complex molecule with three twists but only one surface. This achievement demonstrates their expertise in manipulating molecular structures and has significant potential for future applications in molecular electronics and optoelectronics.
Researchers discovered uric acid's role as a major intracellular antioxidant that prevents oxidative stress and its impact on cancer and aging. The p53-GLUT9 pathway is a mechanism to prevent ROS accumulation, which causes cell damage.
Researchers have identified a specific DNA stretch controlling genes that determine face structure and those producing building materials. The region's regulatory elements affect gene Myc activity, leading to facial changes and increased susceptibility to environmental factors like smoking during pregnancy.
Researchers from the University of Jyväskylä report a new method for building molecular cages that exploits intermolecular steric effects to control self-assembly. This allows for the creation of cages with vacant metal binding sites, enabling modifications to their properties.
A study by the University of the Basque Country reveals that younger immigrant youth perceive discrimination as a major issue, while those from Latin America have a more optimistic view. The research highlights the importance of actively coping with discrimination in improving wellbeing and adaptation to the new social context.
A study published in JAMA Internal Medicine found that low-dose estrogen therapy and low-dose non-hormonal venlafaxine hydrochloride extended release were both effective in reducing hot flashes and night sweats in menopausal women. The treatment options showed similar efficacy, with a slight superiority of estrogen therapy.
A recent study by evolutionary biologists at the University of Massachusetts Amherst shows that a mutation in a single gene during development can lead to different consequences, including changes in jaw shape and feeding strategies. This genetic variation predicts differences in feeding mechanics and alters skull structure.
Researchers discovered that neurons can mobilize calcium from large dense core vesicles to facilitate the release of neuropeptides. This process enables fine-tuning of communication between neurons and other cells.
Scientists have observed the process by which CRISPR enzymes bind and alter DNA structure, paving the way for correcting genetic diseases in humans. The study provides a vital piece of the puzzle for genome editing tools to be used in humans.
Two studies on bronchiolitis treatments yield conflicting results, with one finding less improvement in infants after nebulized hypertonic saline treatment and the other showing decreased hospital admissions. The editorial dissects the contradictory evidence, suggesting chance or differences in study design may be to blame.
A new Ebola vaccine has been successfully tested on captive chimpanzees, producing a robust immune response and showing safety. The researchers argue that this could be a turning point in saving endangered ape species from extinction, but the need for captive chimps testing raises ethical concerns about animal welfare.
Max Planck researchers identify supramarginal gyrus region crucial for children's ability to assess others' emotions, improving with age. The study reveals that adults can easily overcome egocentrism, whereas children between 6-13 tend to project their own emotions onto others.
Vaccination rates among healthcare workers are less than 50%, highlighting the need for policies that balance individual rights with public health. Mandatory flu vaccinations can benefit patient health, but must comply with employment law, provincial human rights codes, and the Canadian Charter of Rights and Freedoms.
Researchers found that cerebral blood flow levels decreased before puberty but diverged sharply after, with females experiencing increased flow and males decreasing further. This divergence may contribute to sex-specific differences in behavior and risk for psychiatric disorders.
A new study has overturned the long-used 'Neutral Theory of Biodiversity' by revealing its flaw: it fails to capture the crucial role of abundant species. The research, covering a vast array of marine ecosystems worldwide, found that these dominant species deliver essential ecosystem services.
NTU's new additive manufacturing centre will focus on developing next-generation 3D printers and platforms for various materials. The centre aims to collaborate with industry leaders, such as SLM Solutions, to drive innovation in the field of 3D printing.
A recent study published in Experimental Economics found that intermediaries significantly increase corruption, regardless of their level of involvement. The researchers designed a laboratory experiment to test the impact of intermediaries on corrupt behavior, and their results confirm this suspicion.
Researchers found that calorie restriction decreased microRNA production, which promotes the extracellular matrix and prevents cancer cells from spreading. The study aims to test whether calorie restriction can improve outcomes for women with breast cancer in a clinical trial.
Researchers found that apolipoprotein E-derived therapeutic peptide improves synaptic stability and learning memory performance after diffuse brain injury. Apolipoprotein E mimetic peptide also reduces neuronal apoptosis by suppressing the ERK1/2-Bax mitochondrial apoptotic pathway.