Scientists applied iPS cell technology to a transgenic nonhuman primate model of Huntington's disease, developing cellular features of the condition and discovering potential therapies for oxidative stress. This approach could aid in the discovery and evaluation of other treatments for the disorder.
A recent study has shown that the addition of carboplatin and/or bevacizumab to standard chemotherapy regimens can significantly increase pathologic complete response rates in stage II-III triple-negative breast cancer patients. This may lead to improved outcomes and reduced risk of relapse.
The University of South Florida will partner with three fire departments to test the effectiveness of supervised exercise programs and web-based interventions on reducing low back pain and disability. The study aims to identify safe and effective exercise interventions for firefighters at risk of back injury.
A study found that modern methods for predicting species distributions under climate change often leave out rare and threatened species. In Africa, over 90% of listed species are missed by popular tools, despite these species being critical to conservation efforts.
The Cardinal Health Foundation awarded Virginia R. Litle, MD, a Thoracic Surgeon at Boston Medical Center, grant funding to study the efficacy of a Caprini Risk Assessment Model and implement an efficient anticoagulation compliance protocol. The initiative aims to reduce venous thromboembolism complications after thoracic surgery.
The new Competence Center for High Performance Computing in the Natural Sciences will facilitate interdisciplinary collaborations and provide improved HPC services. The center will focus on research and application optimization, with a strong emphasis on Big Data and hardware accelerators.
A retrospective single-center study found that restarting infliximab therapy after a drug holiday is safe and effective for IBD patients. The average duration of infliximab holiday was 15 months. Patients who were in remission at the time infliximab was discontinued showed a 78 percent response rate at one year.
Three Clemson startup companies, VRM Labs, ConnectTiss LLC, and Addictive Drug Delivery LLC, have received $25,000 in seed money from the University Sponsored Application Program. The companies are commercializing technologies developed at Clemson to address various industries such as pet food, aging skin, and surgical meshes.
A combination therapy of two miRNAs, let-7 and miR-34, has been shown to suppress tumor growth in an animal model of non-small-cell lung cancer. The study offers a promising therapeutic avenue for this aggressive malignancy.
Research on e-cigarettes reveals potential links to asthma and emphysema, as well as a successful quitting aid, but also raises concerns about long-term effects and lack of consensus among doctors. The ERS Congress emphasizes the need for strong regulation to protect vulnerable populations.
Researchers at Technical University of Munich have discovered a new site where T lymphocytes can be programmed to attack pathogens. The liver plays a key role in this process, and synthetic messenger Hyper-IL-6 has been found to efficiently activate T cells, offering a promising new adjuvant for vaccine formulations.
The TRMM satellite calculated heavy rainfall generated by Hurricane Norbert and Tropical Storm Dolly. Rainfall totals were greater than 300 mm, affecting the open waters of the Pacific Ocean and near Mexico's western and Gulf coasts.
Research reveals that brown tide algae can survive and thrive in conditions degraded by human activity, such as low light and high organic nutrients. The study also highlights the unexpected ability of these algae to pump toxic arsenic out of their cells into water.
Researchers Brooke Feeney and Nancy L. Collins identify two support functions that help individuals thrive through close relationships: source of strength (SOS) support and relational catalyst (RC) support. SOS support enables individuals to cope with stress, while RC support fosters opportunities for growth and positive well-being.
Researchers at UT Southwestern Medical Center have identified several new genetic causes of Wilms tumor, a type of kidney cancer found only in children. The most common mutations were found in genes called DROSHA and DICER1, which affect the production of microRNAs that control cell growth.
A new blood test developed by researchers at the University of Manchester and The Christie NHS Foundation Trust may soon be used to tailor treatment for ovarian cancer patients. The test predicts patient response to targeted therapies such as bevacizumab, allowing for personalized treatment plans while sparing those unlikely to benefit.
A team of scientists used the Hyb-Seq method to sequence hundreds of nuclear loci and plastomes from milkweeds, providing a significant advance over previous methods. This approach combines target enrichment and genome skimming to reduce genomic complexity and increase sequencing efficiency.
The California blue whale population has rebounded to near historical levels, according to new research. The recovery is attributed to careful management and conservation measures, rather than ship strikes or other human-caused factors.
Researchers at Syracuse University have created biomimetic sacs that undergo spontaneous oscillations and tunable frequency, mimicking the behavior of living cells. The discovery has significant implications for the development of artificial cells and clocks.
Researchers found that banked blood membranes become stiffer over time, decreasing the cells' functionality and ability to carry oxygen into tiny microcapillaries. This decrease in functionality can lead to major clinical problems, such as impaired oxygen transport in the brain.
A population-based case-control study found no evidence that wearing a bra increases the risk of breast cancer among postmenopausal women. The study analyzed bra-wearing habits in relation to breast cancer risk using a rigorous epidemiological study design, providing reassurance to women about their bra-wearing habits.
A study published in PLOS ONE suggests that domesticated peaches can be traced back to the lower Yangtze River Valley in Southern China around 7,500 years ago. The researchers analyzed ancient peach stones and found significant growth in size over time, indicating intentional breeding and selection.
The Glanville fritillary genome, approximately 390 million base pairs long, has been fully sequenced at the University of Helsinki. The study confirms a key hypothesis about the ancestral lepidopteran species' chromosome count, revealing stability over 140 million years.
A new vaccine candidate, GP2, has shown a 57% reduction in recurrence rates among high-risk breast cancer patients. The vaccine targets CD8+ cells and was combined with an immune stimulant to enhance its effectiveness.
A new study confirms a strong link between air pollution and lung health in European adults, with people suffering from obesity particularly vulnerable. The findings emphasize the importance of educating about clean air and urge policymakers to update guidelines to meet WHO-recommended air quality standards.
Researchers found that adopting the USDA's 'Dietary Guidelines for Americans, 2010' would lead to a 12% increase in diet-related greenhouse gas emissions due to increased consumption of dairy products and seafood. In contrast, reducing daily caloric intake while shifting to a healthier diet would result in only a 1% decrease in emissions.
The report highlights how stigma, including public and structural forms, prevents individuals from seeking mental health care. Effective approaches to addressing stigma, such as promoting personal stories of recovery and enhancing support systems, are identified.
A new study from the University at Buffalo Research Institute on Addictions found that female college students who experienced severe sexual assault were three times more likely to experience severe sexual assault the following year. The researchers also discovered that women who have been victims may need to be followed for months to ...
The project aims to create a mobile app that enables park visitors to learn about the park's history, ecology, and scientific features while contributing to citizen science. The app will be available for download on Apple and Android devices and will allow users to log in and save their findings.
A new study found that caffeine therapy for apnea of prematurity does not have long-term harmful effects on sleep or control of breathing in children. The study, which assessed 201 preterm children at ages 5-12, showed no evidence of long-term detrimental effects of caffeine treatment on sleep duration or sleep apnea during childhood.
Researchers found that a flu virus can inflame nasal tissue and increase bacterial growth, leading to middle ear infections. The study suggests that the flu virus modifies the immune system's response to certain bacteria, enabling them to infect the middle ear.