A new study published in the European Society of Cardiology reveals that prolonged television watching is associated with a higher risk of fatal pulmonary embolism. Watching TV for more than five hours per day was linked to twice the risk of death from pulmonary embolism as watching less than two and a half hours daily.
The new guidelines introduce a novel treatment algorithm for pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH), recommending sequential and initial combination therapies based on patient risk profiles. The guidelines also provide updated classifications, diagnostic algorithms, and assessmen...
A major multi-national study of suicides identified behavior patterns preceding many suicide attempts. The study found that patients with depressive mixed states were at higher risk of suicide, as well as those displaying risky behavior, psychomotor agitation, and impulsivity. These findings suggest the importance of assessing these sy...
Researchers found that a single dose of cocaine interferes with recognizing negative emotions, such as sadness and anger. The study's lead author suggests this may explain why cocaine users report higher levels of sociability when intoxicated.
NASA's GOES-East satellite tracked Tropical Storm Erika's movement from August 27 to August 29, showing its weakening as it passed through the Leeward Islands and into the Eastern Caribbean Sea. The storm's remnants are expected to produce heavy rainfall across portions of the Dominican Republic, Haiti, and eastern Cuba through Sunday.
A European Union-funded project estimates that 4.7 million tonnes of discarded electronics were wrongfully mismanaged or illegally traded in Europe, valued at €800-1.7 billion annually. The study calls for better guidelines and harmonized penalties to combat e-waste crime.
Research found that midday naps are associated with reduced blood pressure levels and prescription of fewer antihypertensive medications in hypertensive patients. Midday sleepers had lower average 24 hour ambulatory systolic BP readings, indicating a potential reduction in cardiovascular risk.
Researchers found that patients with high risks of MI and bleeding were admitted for NSTE ACS on warmer, sunnier days with higher carbon monoxide and ozone air concentrations. Treatment with percutaneous coronary intervention (PCI) was more successful when the weather was sunnier but colder and with lower concentrations of air pollutants.
A new study has found that targeted magnetic pulses cause biochemical and connectivity changes across the brain in depressed patients. The research suggests that personalized TMS treatment could lead to better, more targeted therapy for depression and other conditions.
Researchers found that nearly 60 out of 100 000 people suffer cardiac arrest outside the hospital each year and only one in ten survive. In a large study, patients with refractory cardiac arrest who were brought to the hospital with ongoing CPR had a higher survival rate compared to those resuscitated before arrival. The study's findin...
The ESC recommends DNA analysis in post mortems of young sudden death victims to identify genetic causes and facilitate early diagnosis of relatives. This approach helps protect them through personalized approaches, such as lifestyle modifications and therapies.
The ESC guidelines now strongly recommend the radial approach over femoral access for coronary angiography and PCI in patients with acute coronary syndromes. The radial approach reduces vascular complications, major bleeding events, and all-cause mortality. Additionally, the guidelines suggest a tailored duration of dual antiplatelet t...
Scientists from Hiroshima University have observed an unusual dispersion of the acoustic mode in liquid Bi using inelastic x-ray scattering (IXS). The results resolve previous disagreements and suggest a possible mechanism involving a long-range interatomic force, which is related to local structures.
Researchers at the University of Illinois have developed a new technique to create synthetic tissue environments that can realistically recreate microenvironments found in biology. This allows for more accurate study of tumor growth and behavior, and has potential applications in drug screening and personalized medicine.
Researchers have developed a light-activated switch that enables precise control of NMDA receptors, which are crucial for forming and storing memories. This tool promises to provide new insights into the mechanisms underlying synaptic plasticity and memory formation.
Researchers at OU and Mercy Hospital OKC are developing two new short-term breast cancer risk prediction approaches to increase detection of breast MRI screenings. They aim to identify high-risk women with mammography-occult cancers and reduce repeated negative MRI screenings among those with elevated risk.
The Philistines brought exotic plants, including sycamore, cumin, and opium poppy, which had a significant impact on Israel's floral biodiversity. These cultivars were not found in archaeological sites prior to the Iron Age, reflecting a distinct agrarian regime and dietary preferences.
Four UC San Diego School of Medicine researchers have received the NCI Outstanding Investigator Award for their groundbreaking research in cancer. Kun-Liang Guan, Tannishtha Reya, Jin Zhang, and Michael Karin will receive multi-million-dollar awards to fund new projects tackling cell growth, cancer detection, and treatment.
A 23-year experiment by Lund University researchers found that fungi break down organic materials, releasing carbon dioxide and nutrients, rather than reducing leakage as previously thought. This challenges current policies on land use intended to promote fungi and could have significant consequences for climate models.
A team of scientists has discovered that gene regulatory networks are inherently unstable, leading to aging and disease. Stabilizing these networks could lead to therapies against age-related diseases and increased lifespan.
Scientists have created a nanoscale vehicle made of DNA to shuttle the CRISPR-Cas9 gene-editing tool into cells. This 'nanoclew' ensures precise control over the dosage of editing, reducing unintended edits. The researchers successfully tested the system in cancer cell cultures and tumors in mice, achieving promising results.
Kyriakos S. Markides, PhD, receives the prestigious Robert W. Kleemeier Award from GSA for his contributions to the study of aging. The award recognizes his extensive research on Hispanic health outcomes and epidemiological paradoxes.
A recent study found that drinking less alcohol is the most effective way to avoid hangovers, contrary to popular claims that eating water or consuming hydrating drinks can prevent them. Researchers surveyed over 1,300 students and found no correlation between hydration and hangover severity.
Researchers at California Institute of Technology have developed an artificial leaf that can harness sunlight to produce hydrogen fuels, achieving a high efficiency rate. The system consists of three components: photoanode, photocathode, and membrane, which work together to split water molecules into oxygen and hydrogen gas.
Mary Naylor, a renowned gerontological nurse researcher, has been awarded the 2015 Doris Schwartz Gerontological Nursing Research Award by GSA. Her Transitional Care Model has been clinically proven to reduce hospital re-admissions and produce substantial savings.
Researchers at Caltech have successfully observed and controlled quantum motion in a large mechanical device, defying classical physics. By manipulating the inherent quantum noise, they were able to reduce its impact on measurement precision.
Research found that oysters serve as a major reservoir for noroviruses, with over 80% of human norovirus genotypes detected in oyster samples. This highlights the importance of surveillance and safe handling of oysters to prevent transmission.
Tropical Storm Erika was centered in the Eastern Caribbean Sea, affecting Puerto Rico and Hispaniola. The storm produced total rainfall accumulations of 3 to 6 inches with maximum amounts of 10 inches possible across portions of the Dominican Republic and Haiti.
Engineers at the University of Toronto have developed a biocompatible scaffold that allows sheets of beating heart cells to snap together like Velcro. This technology enables the creation of layered tissues with varying configurations, including tiny checkerboards, and could be used to repair damaged hearts.
A USC study reveals inaccuracies in CPR depictions on TV, including lower survival rates and incorrect patient demographics. The findings highlight the need for improved physician-patient communication and discussions around advance care planning decisions.
Researchers have developed a new method to manufacture hybrid glasses using metal-organic frameworks (MOFs), enabling industrial-scale carbon capture and storage. The technique allows for the production of 'designer glasses' with applications in advanced photonics.
Researchers found that 'Bicycles May Use Full Lane' signs were more effective in clarifying the rules of the road for both drivers and cyclists. This new signage could lead to increased bike usage, reducing traffic congestion and greenhouse gas emissions, while improving public health and mobility for disadvantaged groups.
A study by psychologists at the University of Rochester found that mothers who experienced childhood maltreatment have lower self-confidence and are more likely to use negative parenting behaviors. Intervention programs should focus on building mothers' confidence, rather than just teaching parenting skills.
Heavy rainfall from Hurricane Ignacio was measured by NASA's Global Precipitation Measurement (GPM) core satellite on August 27, with rates reaching over 60 mm per hour south of the eye. The storm is expected to slowly strengthen through late Saturday and peak at 110 mph on August 29.
A landmark paper recommends monitoring beach sand to safeguard human health. The study, based on data from beaches in the US, UK, Portugal, and other countries, identifies key indicators and methods to assess public health risks from pathogens in the sand.
A study at the University of Illinois identified p-coumaric acid as a key factor in determining honey bee caste. The research found that larvae fed with beebread and honey containing p-coumaric acid undergo changes in gene expression, shifting them away from queen development.
Climate change and rising temperatures are giving rise to 'hotter' droughts, causing abnormally high levels of forest mortality. Temperate forests may convert to new ecological states, leading to widespread ecosystem service losses.
Hurricane Jimena is rapidly intensifying due to its strong thunderstorms building up quickly, especially in its northern quadrant. The storm's maximum sustained winds are expected to reach 145 mph, making it a powerful Category 4 hurricane on the Saffir-Simpson Scale.
A study by Helmholtz Munich researchers identified a key role of the protein BMP7 in promoting cell division and migration in pheochromocytoma cells. Targeting this signaling pathway with specific substances may lead to an increase in apoptosis, providing a new approach for treatment.
Researchers at H. Lee Moffitt Cancer Center are developing a blood test using microRNAs to identify and characterize precursor lesions that can progress to pancreatic cancer. The test may help differentiate between low- and high-risk lesions, allowing for more informed personalized medical management decisions.
Research suggests that fetal microchimerism can have both cooperative and competitive effects on maternal health, depending on the context. Fetal cells may provide benefits by migrating to damaged tissue and repairing it, while also contributing to inflammatory responses and autoimmunity in some cases.
Researchers at IRB Barcelona found that tumor suppressor genes restrict the growth of neighboring cell populations, a mechanism that may contribute to cancer development. This discovery could provide insight into the early events of tumorigenesis and the selection of tumour-initiating cells.
Jae Kyoung Kim's research uses mathematical modeling and synthetic biology to understand how biological circuits generate and sustain stable rhythms. The study found that a novel bacterial circuit generates robust rhythms under various conditions, providing insights into the fundamental mechanism of rhythm generation in biological syst...
Tropical Storm Kilo displays a giant comma shape in infrared imagery from NASA's Aqua satellite, indicating powerful thunderstorms with heavy rainfall potential. The storm is forecasted to strengthen and become a hurricane over the next couple of days.
A new study published in the American Journal of Psychiatry has discovered a predictive fMRI-derived measure that significantly predicts patients' response to antipsychotic medication. This breakthrough enables the use of brain scans as a tool for guiding treatment and improving patient outcomes.
The Gerontological Society of America has selected Eric R. Kingson as the recipient of the 2015 Donald P. Kent Award, recognizing his exceptional professional leadership in gerontology through teaching, service, and practice. Kingson is a professor at Syracuse University and has written extensively on politics and economics of aging, r...
A research group in Japan and Korea found that certain dipeptide species support CML stem cell activity. Pharmacological inhibition of nutrient uptake decreased CML stem cell activity in vivo, suggesting a potential therapeutic target for CML therapy. This discovery may provide concrete benefits to patients with CML.
Research by Dr. Fabrice Jollant found that high-risk decision-making among parents of individuals who committed suicide may contribute to their vulnerability. The study suggests that cognitive training and neurostimulation techniques can help improve decision-making skills, reducing the risk of suicide.
A patient with an immune deficiency has shed large amounts of live polio virus in their stool for over 20 years, posing a risk to global polio eradication. The highly mutated strain has acquired mutations that reverse the attenuating features of the vaccine strain, making it more difficult to neutralize.
Eyes with peripheral diabetic retinal lesions have a three-fold increased risk of progression to advanced stages of vision-threatening diabetic retinopathy. The findings suggest that wider field imaging may change how diabetic eye disease is evaluated and treated.
Researchers at Monash University developed a new non-invasive image processing technique to visualize embryo formation, challenging the prevailing model of cell placement. This breakthrough offers potential for improving IVF success rates by selecting embryos with optimal inter-cellular forces.
Smiling Brazil launched in 2004 and incorporated oral health into the public healthcare system, adopting an integral care approach. The policy has shown positive results in oral health epidemiological indicators, financial investment, and professional development.
A new study suggests that fish oil diets are more effective than lard diets due to the presence of certain gut bacteria. Mice transplanted with gut microbes from a fish oil diet showed reduced weight gain and inflammation compared to those with lard diet microbes.
Researchers developed a model to simulate Mediterranean tsunami impact, showing how waves would hit and flood coastal areas in southern Italy and Greece. The study highlights the need for local authorities to identify vulnerable areas and plan defense strategies.
Researchers at UC San Francisco discovered that the adaptive immune system plays a role in guiding the normal development of mammary glands in mice. The immune system puts brakes on cell growth to fine-tune structure, a process that may also apply to other organs such as the prostate gland and skin.
A recent study suggests that nitroglycerin could be repurposed as an anti-cancer treatment by improving tumor oxygenation and delivering anticancer drugs. The medication, traditionally used for chest pain, has excellent potential for patient benefit without significant side effects.
The discovery reveals protein structural changes that could inform treatments for inflammatory conditions such as heart disease and colon cancer. The researchers found that two proteins, Tollip and Tom1, work together to regulate the turnover of cell-surface receptor proteins that trigger inflammation.
A decade-long study shows growth hormone continues to reduce fracture risk and maintain bone density in postmenopausal women with osteoporosis. The treatment's effects were found to last for years after it was administered.
Research found adolescents with ADHD showed differences in brain structure and poor memory performance compared to peers, suggesting ADHD may persist into adulthood. Grey matter deficits in the caudate nucleus region were linked to poorer memory function.
Hurricane Ignacio strengthened to a hurricane after showing very cold cloud tops, indicating stronger uplift in tropical cyclones. The storm's maximum sustained winds increased to near 85 mph with forecasted peak strength on August 29.