Studies show that patients who access their clinician's visit notes experience improved health outcomes, better medication adherence, and reduced diagnostic delays. The practice of sharing visit notes has the potential to enhance patient-clinician communication and improve safety.
The Massachusetts Rett Syndrome Association and Rettsyndrome.org are partnering to support a Phase 2b clinical trial of IGF-1 for the treatment of Rett syndrome. The trial, funded by a $439,000 grant from Rettsyndrome.org, aims to develop new biomarkers and treatments for the condition.
A study published in the Journal of American Geriatrics Society found that chemotherapy's effectiveness in prolonging life for older adults with most types of cancer is reduced for women over 80 with breast cancer. However, combining chemotherapy with another treatment may improve mortality risk reduction for this age group.
Researchers at MIT have developed paraffin-based capsules that can enclose multiple reagents and catalysts, simplifying chemical synthesis. The capsules can protect water-sensitive compounds for extended periods, extending the shelf life of common commodity chemicals.
Participants with late-stage retinitis pigmentosa are being enrolled in the clinical trial to test the safety of retinal progenitor cells. The open-label phase I/IIa trial aims to evaluate the treatment's efficacy in preserving vision by protecting and potentially reactivating degenerating photoreceptors.
Scientists observed a rare Pacific striped octopus species exhibiting unusual cohabitation, hunting, and mating behaviors. The species challenges conventional understanding of octopus reproduction, displaying intimate beak-to-beak interactions during mating.
Research published in Diabetologia found that insulin resistance is associated with poorer verbal fluency in women, a sign of cognitive decline. The study also discovered that higher insulin resistance is linked to slower reaction times and increased risk for Alzheimer's disease in this demographic.
A comprehensive review of available evidence confirmed that listening to music before, during, and after surgery reduces postoperative pain, anxiety, and the need for painkillers. The study involved nearly 7,000 patients and found music to be effective even when patients were under general anaesthetic.
The California two-spot octopus genome was fully sequenced, revealing widespread genomic rearrangements and a dramatic expansion of genes involved in neuronal development. The findings provide an important foundation for evolutionary studies and deeper investigations into the genetic mechanisms underlying cephalopod-specific traits.
Researchers identified a pathway that leads to atypical blood vessel formation in age-related macular degeneration. Inhibiting this pathway may halt or restore sight in people with the disease.
A new Johns Hopkins study finds that people infected with hepatitis C virus are at increased risk of cardiovascular damage, independent of HIV. Chronic infection leads to abnormal fat-and-calcium plaques in arteries, a common precursor to heart attacks and strokes.
New research links mGluR5 receptor loss in parvalbumin-positive interneurons to neurodevelopmental disorders like autism and schizophrenia. The study suggests that alteration of these receptors may be a critical step in the formation of some neurodevelopmental disorders, with potential for reversal.
University of Wisconsin-Madison researchers have discovered a way to grow graphene nanoribbons directly on germanium semiconductor wafers, overcoming precision and edge quality issues. The technique enables the mass production of nanoribbons with desirable semiconducting properties for high-performance electronics.
A study published in JAMA found that using frozen donor eggs for IVF is linked to lower live birth rates compared to fresh eggs. The study analyzed data from over 11,000 cycles and found that per started cycle, the live birth rate was 43% with frozen eggs vs 50% with fresh eggs.
Researchers have discovered a way to trigger a preventive response to flu infections by boosting the level of IFITM3 protein in cells, preventing cell infection. The method involves inhibiting NEDD4 enzyme, which degrades IFITM3, allowing for sustained production and enhanced resistance to flu viruses.
A three-year study led by QUT found that controlling feral pigs is the most cost-effective strategy to conserve 148 endangered plant and animal species in the Lake Eyre Basin. Implementing these strategies could increase food production by up to 10% and save the Australian economy $5 billion annually.
Researchers investigated dog food processing methods to combat pet obesity, finding that particle size affects digestibility. Maize and sorghum-based diets required coarser grinding for optimal gelatinization, whereas rice-based diets were more easily digested regardless of particle size.
Researchers found that a slight deflection in natural gravity at Greenwich causes the offset. The study's findings confirm that newer technologies like GPS have replaced traditional methods of determining longitude.
A team of Vanderbilt investigators has discovered that fibrin breakdown is essential for fracture healing, contradicting previous assumptions. The findings have significant implications for efforts to promote fracture repair and may lead to new treatments by reducing or enhancing fibrin levels.
EPFL scientists have developed a new method called cryofixation to preserve the brain's true structure, overcoming distortion caused by traditional fixation methods. This breakthrough allows for unprecedented detail in brain imaging and has significant implications for understanding brain anatomy and function.
A study published in The BMJ found that trans fats are associated with a greater risk of death and coronary heart disease, but saturated fats are not. The study suggests that industrial trans fats may increase the risk of coronary heart disease and calls for a review of dietary guidelines.
BioWardrobe, a user-friendly platform, enables researchers to analyze large transcriptomic and epigenomic datasets without programming expertise. The platform was developed to bridge the gap between data and knowledge, facilitating research on basic biology and disease.
Researchers from MDC and Charité elucidate the process of skeletal muscle atrophy in patients with congestive heart failure, identifying a new regulator and signaling pathway. The study reveals that angiotensin II induces muscle atrophy through the activation of MuRF1, but also highlights potential therapeutic targets to prevent furthe...
Johns Hopkins and Mayo experts suggest upgrades to current heart disease prevention guideline, focusing on improved risk prediction and personalized treatment. The new guidelines aim to clarify key points of confusion related to risk prediction and treatment of heart attacks and strokes, promoting more precise and tailored care.
A study published in the British Medical Journal found that insulin pump users had a substantially lower risk of dying from cardiovascular disease than those using multiple daily injections. The researchers believe more frequent monitoring and training may be key to the therapy's benefits.
A new study found that only one in four patients with end-stage renal disease (ESRD) in Georgia was referred to a transplant center for evaluation within one year of starting dialysis. The study also revealed substantial variation in referral rates among dialysis facilities.
Researchers used satellite observations and atmospheric modeling to calculate the impact of fires from industrial concessions on air quality. The study found that these fires contribute significantly to air pollution, particularly in regions with degraded peatlands and deforested areas.
A recent study by University of California, Riverside researchers found that men and women use social media and online health forums differently. Women primarily use these platforms to discuss specific health conditions, whereas men focus on health news and healthcare policy. This research can help public health officers target underre...
The UK is the worst offender in European avoidable food waste, with nearly 80% of all food waste being avoidable. The study found that vegetables, fruit and cereals contribute most to lost resources, while meat production uses more resources in the first place.
A team of scientists resolved a discrepancy in the decay energy of Holmium-163, paving the way for measuring the neutrino mass. The research used the Penning-trap mass spectrometer SHIPTRAP and confirmed a decay energy of 2,833 eV with high precision.
Researchers at UT Southwestern Medical Center found that exercise can help alleviate excessive daytime sleepiness in depressed individuals by reducing two biological markers associated with hypersomnia. The study identified the biomarkers and showed that exercise reduced their levels, resulting in improved symptoms.
Scientists successfully induced colossal magnetoresistance in pure lanthanum manganite for the first time using high-pressure conditions. The phenomenon occurs when the competition between two phases is at its maximum, driving the transition from an insulator to a metal. This breakthrough has significant implications for harnessing col...
A new study highlights the unique challenges of adolescent sibling stem cell donation, including health risks, pain, and psychological burdens. The authors argue that the role of siblings in providing life-sustaining stem cells has been taken for granted.
The new journal aims to publish current research on scars, burns, and healing from a range of clinical and academic authors. The partnership between SAGE and The Katie Piper Foundation seeks to improve the delivery of burns rehabilitation and scar management.
Typhoon Soudelor produced over two feet of rainfall when it made landfall in China and Taiwan, with the rugged terrain amplifying totals to 1320 mm (52 inches) in Taiwan. NASA estimated the rainfall using data from its Global Precipitation Measurement mission.
A study published in the British Medical Journal found that trans fats are associated with a 34% increase in death for any reason, while saturated fats showed no clear association with an increased risk of death or heart disease. However, researchers recommend replacing high-fat foods with vegetable oils, nuts, and whole grains.
Keystone Symposia has received a five-year, $2.25 million grant from the Bill & Melinda Gates Foundation to support Global Health Series meetings and Travel Awards for scientific investigators and clinicians from low and middle-income countries.
A study found that only about one in four patients with end-stage renal disease in Georgia were referred for kidney transplant evaluation within a year of starting dialysis. The study suggests that standardized guidelines are needed to improve access to kidney transplantation.
A new Penn study found that hydrogen sulfide regulates Treg cells by modifying a transcription factor called NFYB, leading to improved function and development of these regulatory cells. The study suggests potential therapeutic interventions for autoimmune diseases, cancer, and hypertension.
SwRI scientists suggest that geologic activity brings nitrogen up from Pluto's interior to resupply its atmosphere. They also consider the possibility of cryovolcanism and ongoing geysers as sources of nitrogen.
NHS trusts under severe financial pressure are least likely to terminate expensive PFI contracts, warns expert. Alternative solutions, such as adjusting commissioner payments to compensate for capital costs, are considered more effective.
Researchers constructed an atomic model of an immature retrovirus, revealing key structural features and a six-helix bundle domain that may be a target for blocking the virus. This breakthrough could lead to the development of new anti-retroviral drugs.
A study by Scott Adler and Audrey Wong-Kee-You found that C-sections influence spatial attention in babies, slowing their ability to prioritize and focus on a particular area or object. In contrast, cognitive-driven attention remained unaffected.
Researchers have successfully implemented superposition of quantum gates, allowing for increased efficiency in quantum computations. This breakthrough could pave the way for faster quantum computers.
A national co-management intervention aims to improve person-centered care outcomes and decrease healthcare spending. The program, supported by the John A. Hartford Foundation, positions geriatrics professionals as co-leaders in pre- and post-operative management of older adults with fragility fractures.
Researchers found that gastric bypass surgery enhances energy expenditure, allowing patients to lose and maintain weight over time. The study used a metabolic chamber to track the body's energy requirements before and after surgery.
The book series will be published in six electronic issues per year, featuring topical review articles covering present and future trends in modern chemical research. This format allows for faster indexing, discovery, and citation of contributions.
A three-year clinical trial found no link between testosterone administration and atherosclerosis progression, sexual function, or quality of life in older men. The study suggests that testosterone should not be used indiscriminately by men, as it may not provide benefits for these outcomes.
A new study reveals that lager yeasts originated from a hybrid of two yeast species, Saccharomyces cerevisiae and S. eubayanus, with two independent origin events detected. The findings suggest that domestication for beer making has placed yeast on similar evolutionary trajectories multiple times.
Researchers found that therapists using Socratic questioning techniques led to substantial improvements in depressive symptoms for patients. The therapy involves guided questions to help patients re-examine their negative thoughts and gain a broader perspective.
A Lab-on-a-Disc platform developed by German and Irish researchers detects bacterial species causing urinary tract infections in 70 minutes, significantly reducing wait times compared to traditional methods.
Researchers found a potential biomarker, limonene, in breath samples of patients with cirrhosis, which gradually dropped after liver transplant. The study aims to develop a non-invasive diagnostic tool for early-stage liver disease diagnosis.
Researchers at Nova Southeastern University found that localized derby efforts are insufficient to curb the lionfish population, emphasizing the need for consistent removal across all areas of their habitat. The study recommends targeting all lionfish ages and sizes, as well as considering ocean currents' impact on larvae spread.
A 3-year testosterone supplementation study found no significant association between treatment and atherosclerosis progression. The trial also showed no improvements in sexual function or quality of life, despite increased hematocrit and prostate-specific antigen levels.
The researchers developed a new algorithm using geometric matching and machine learning to analyze style similarity in 3D objects. They achieved an agreement rate of 90% with human evaluations, making it a valuable tool for computer graphics applications.
Northeastern University researchers introduce a new metric called 'control energy' to characterize the effort needed to control real-world complex systems. This enables a kind of network cost-benefit analysis, allowing scientists to identify the minimum number of driver nodes required for input signals and optimize network control.
The International Association for the Study of Lung Cancer (IASLC) has selected 5 advocates to attend the 16th World Conference on Lung Cancer, where they will share and learn strategies to increase awareness. The recipients include Hildreth Grossman, Kathleen Mewhiney, Victor Lasebikan, Seda Kansu, and Tetsuya Yamaoka.
The Suomi NPP satellite captured a stunning night-time image of the Jerusalem Fire in California, revealing its massive size and location. The fire has covered over 12,000 acres and is being managed by Cal Fire.
Researchers discovered that chitosan, derived from insect and crustacean shells, can effectively destroy up to 90% of pathogens in selected cell cultures. This biopolymer has been found toxic to pathogenic microorganisms, disrupting their membranes without harming healthy cells.
Researchers found that the evolutionary loss of the worker caste in ants is not accompanied by a loss of genes. Instead, most genes are expressed in both queens and workers, but often at different points in development. Regulatory changes may have facilitated the evolution of sociality.