Researchers at Washington University School of Medicine identified a key player in maintaining brain tumor stem cells' ability to survive and replenish themselves. Disrupting this process using protein CDC20 has been shown to reduce tumor growth by up to 95 percent in mice, offering new hope for treating glioblastoma.
A new study published in the American Journal of Clinical Nutrition found that a DASH-style diet with lean, unprocessed pork as the primary protein source reduced blood pressure and had similar effects when chicken or fish was used instead. The study included 19 participants with elevated high blood pressure and demonstrated the versat...
NASA's RapidScat and Terra satellites observed Tropical Depression 3-E forming in the Eastern Pacific, with sustained winds near 15 meters per second (33.5 mph) and a powerful thunderstorm band spiraling into its center.
A new study published in PNAS found that groups outperform individuals in detecting lies, with a 61.7% group accuracy rate compared to 53.5% individual accuracy. The researchers discovered that the group advantage comes from the process of group discussion rather than statistical aggregation of individual opinions.
Children with lower vitamin D levels had higher blood markers related to kidney dysfunction and greater kidney function loss over time. Maintaining normal vitamin D levels helps preserve kidney function in children with CKD.
A new study integrates neuroscience and psychology to reveal how sleep suppresses the activity of certain nerve cells that promote forgetting, ensuring at least some memories last. Sleep facilitates memory retention by blocking dopamine neuron-mediated forgetting, leading to more stable memories.
A new study found that Connecticut's permit-to-purchase handgun law, which requires background checks and safety training, led to a 40% drop in firearm-related homicide rates. The law also raised the purchasing age to 21 and restricted sales to licensed dealers.
Harvard researchers argue that mobile devices could revolutionize healthcare by linking app data to electronic health records. This integration could reduce costs and advance precision medicine, but current electronic health record systems lack standardized interfaces for accessing genomic data.
Researchers at the University of Illinois investigated threonine biomass as a lower-cost alternative to fish meal for pig diets. Threonine biomass was found to contain more crude protein and have higher protein digestibility compared to fish meal, making it a promising source of protein for pigs.
A large population study found an increased risk of developing Psoriatic Arthritis among psoriasis patients exposed to physical trauma, particularly bone and joint traumas. The study suggests further investigation into the complex factors leading to arthritis in psoriasis patients may lead to modified risk.
Researchers identified 136 genes whose expression is correlated across regions within each network, suggesting a molecular basis for synchronized physiological interactions. These genes encode proteins essential for nerve cell activity and maintenance of voltage differences.
A study by the American Heart Association found that culturally tailored educational materials can decrease racial disparities in stroke preparedness outcomes. Interactive interventions and enhanced educational materials led to a significant increase in patients arriving at emergency departments within three hours of symptom onset.
A new study reveals that hawkmoths' vision is finely attuned to the swaying of flowers in the breeze, enabling them to track wind-tossed flowers under low-light conditions. The researchers found that the moth's tracking responses were slower in dark conditions, but only when the artificial flower moved at high frequencies.
The study found that children's exposure to second-hand smoke has declined by approximately 80% since 1998. Over two-thirds of all children now have undetectable levels of cotinine in their saliva, a nicotine derivative.
A study published in Cancer Epidemiology, Biomarkers & Prevention found that lung cancer patients with comorbidities such as chronic obstructive pulmonary disease, diabetes, or congestive heart failure had a higher risk of death. These patients also experienced poorer survival rates at each stage of the disease.
A recent study found that less competitive strains of Myxococcus xanthus can retain their genetic diversity by occupying niches inaccessible to dominant strains. This phenomenon, known as positive frequency-dependent selection, allows weaker gene variants to survive and thrive when numerically superior.
Forefront: Innovations in Suicide Prevention is receiving a $100,000 grant from Washington Women's Foundation to expand its outreach to six underserved rural communities. The organization plans to train over 1,260 individuals and provide technical assistance through the two-year life of the grant.
A recent study found that the new NICE thresholds for diagnosing gestational diabetes in pregnancy are less effective than international criteria, potentially missing thousands of women at high risk. The research suggests that using the WHO guidelines could identify an additional 3,000 to 4,000 women each year in the UK.
Three scientists have been recognized for their groundbreaking discoveries in superconducting materials, including Xianhui Chen, Zachary Fisk, and Zhongxian Zhao. The prize is awarded annually by the Texas Center for Superconductivity to innovators in the field of superconducting materials.
A lab study found that daily aspirin was effective at blocking breast tumor growth. Aspirin appears to affect cancer stem cells, preventing them from reproducing. Experts recommend consulting a doctor before starting a daily aspirin regimen due to potential risks and side effects.
The research develops a system to produce soft materials with dynamically controllable and reversible surface properties. By manipulating the spacing and shapes of embedded particles, the material's surface can change from smooth to ridged or bumpy, creating complex patterns that could guide fluids.
Researchers at Queen's University Belfast have developed a new treatment that prevents Klebsiella pneumonia from blocking the body's natural defences. The therapy uses an inhibitor to stop the superbug from taking over a protein in white blood cells, making it capable of killing the infection.
A large outcomes study found that community-acquired pneumonia increases long-term morbidity and mortality rates compared to the general population. CAP patients have high rates of all-cause hospitalization, emergency department visits, and pneumonia-related hospital visits.
Researchers found that low birth weight, having older siblings, and hospitalizations due to infections between ages 5-16 can predict ankylosing spondylitis. These environmental factors have been linked to other diseases, such as autoimmune conditions like diabetes and rheumatoid arthritis.
The university will create a new generation of tools to develop novel architectures combining hard and soft materials for electronics and biomedicine. The 4-D printer will use nanoscale technology to construct devices for research in chemistry, materials sciences, and U.S. defense-related areas.
A study analyzing 4,200 Ph.D. candidates found that 'joiners' - employees who support startup founders - share similar risk-tolerance and autonomy desires as founders, but prioritize functional roles over management. The research highlights the importance of preparing STEM doctorates for entrepreneurial employee career paths.
The Pew Charitable Trusts has named 10 postdoctoral scientists from Latin America to pursue research in the US with distinguished mentors. The fellows will focus on improving human health through bold approaches to biomedical research.
A study by Penn State researchers found that many of America's most admired companies have room for social media improvement, with some lacking basic accounts and others struggling to create engaging content. Companies in the consumer packaged goods industry excelled in this area, while those in healthcare struggled.
Researchers at Lehigh University present breakthroughs in capturing tumor cells, creating bioengineered enzymes to fight bacterial biofilms, and developing a stable chemical reagent. These innovations have the potential to positively impact industries such as food safety and medical devices.
Research found that consuming at least 10g of nuts or peanuts daily lowers mortality rates for various causes, including respiratory disease and neurodegenerative disorders. The effects are seen in both men and women, with equal reductions.
A new mathematical model investigates the impact of individual movement on infectious disease spread, finding that spatial dispersal can create up to nine stable equilibria. The study highlights the importance of considering both backward bifurcation and spatial mobility in epidemiology.
Researchers studying blue whales in Chile have discovered that a female named 'Isabela' has traveled at least 5,000 kilometers from the Gulf of Corcovado to the Galapagos Islands, indicating a possible breeding ground. This journey represents the largest north-south migratory movement ever recorded for a Southern Hemisphere blue whale.
A Johns Hopkins study analyzed Medicare claims to confirm a long-suspected link between lower rates of coordinated health care services and higher rates of unnecessary medical tests and procedures. Patients with more continuity in their medical care had a lower chance of having an overused procedure.
The Pew Charitable Trusts and Alexander and Margaret Stewart Trust announced five early-career cancer researchers as Pew-Stewart Scholars. They will receive flexible funding to pursue innovative work aimed at advancing progress toward a cure for cancer.
Researchers discovered that injecting water into an inactive fault can cause aseismic slip, which may lead to micro-earthquakes. This study offers insights into the role of friction in fluid-filled faults and could guide monitoring at injection sites.
Women with systemic lupus erythematosus (SLE) and/or antiphospholipid syndrome (APS) are at increased risk of reduced fertility and pregnancy complications. EULAR's new recommendations provide guidance on supporting family planning, assisted reproduction, and healthy pregnancy in these patients.
Researchers used virtual reality to investigate how humans navigate in the dark, confirming a similar navigation system to that found in rats. Participants performed tasks with varying enclosure sizes, showing consistent results with predictions from previous studies and rat experiments.
Min Yu, a USC stem cell researcher, has been named a Pew-Stewart scholar for her work on metastatic breast cancer. She aims to identify molecular adaptations and genetic mutations that allow circulating tumor cells to establish new tumors throughout the body.
A large-scale analysis found that postmenopausal women who were overweight and obese had a higher risk of invasive breast cancer compared to those of normal weight. The study, published in JAMA Oncology, suggests that obesity may contribute to an increased risk of breast cancer.
A global study synthesizes data from 1980 to 2014 to better understand how drought affects different legume species and soil conditions. The results show that the magnitude of yield loss varies with legume species and phenological state during drought, while soil texture also plays a role.
The University of Cincinnati has developed a patent-pending breakthrough in 'tunable' window tintings that can dynamically adapt to brightness, color temperatures, and opacity. This technology allows for simultaneous control of brightness and color temperature, providing options for adjusting light entry while maintaining privacy.
Women experiencing more menopausal hot flashes, particularly at night, are more likely to have brain changes that increase their risk of cerebrovascular diseases such as stroke. This study found a correlation between the frequency and severity of hot flashes and white matter hyperintensities on brain scans.
A new study from the University of Copenhagen found that using the intestinal hormone GLP-1 in obesity treatment prevents bone loss and increases blood levels of bone formation markers. This has significant implications for future obesity treatment, particularly for menopausal women at risk of osteoporosis.
The US National Science Foundation is launching the Exploring Innovation Frontiers Initiative (EIFI) to identify emerging models of technological innovation that will propel US competitiveness in the coming decades. The two-year initiative aims to explore innovation strategies, tap into the nation's innovation capacity, and nurture new...
A recent study found that pre-diagnostic short sleep duration and frequent snoring are associated with significantly poorer cancer-specific survival rates among women with breast cancer. The research suggests that improving sleep patterns may motivate and empower cancer patients to enhance their survival rates.
Researchers have identified a gene, PRDM8, linked to early loss of night vision in animal models. Gene therapy for Leber's congenital amaurosis shows promising results, but temporary improvements are seen.
A phase III clinical trial shows necitumumab significantly improves median overall survival in stage IV squamous non-small cell lung cancer patients. The drug's 'fully human' EGFR antibody approach demonstrates potential as a novel immunotherapy strategy.
A UCLA study finds that children with autism spectrum disorder who are overly sensitive to sensory stimuli have brains that react differently, leading to a condition called sensory over-responsivity. The research may lead to interventions that can help improve the lives of these children and their families.
A new imaging technique uses discrete wavelength decomposition to analyze functional connectivity in the brain, identifying changes in neural communication following mTBI. The study found alterations in connectivity in both acute and chronic stages of injury, with recovery of connectivity over time.
MyApnea.Org is a virtual community portal that recruits patients, caregivers, and at-risk individuals to collaborate on sleep apnea research and improve diagnosis and treatment. Members have access to tools and can suggest research ideas to be voted on by the community.
Researchers found that teenagers and young adults with congenital adrenal hyperplasia have significantly more abdominal fat tissue, which increases their risk for harmful conditions such as cardiovascular disease. The study suggests a need for targeted prevention and therapeutics to avoid these adverse effects.
Researchers at Goethe University Frankfurt have developed a new class of organic luminescent materials featuring blue fluorescence, which are suitable for use in organic light-emitting diodes. The boron-containing nanographenes exhibit improved electron transport and stability, making them ideal for portable electronic devices.
A new psoriasis drug, ixekizumab, has shown significant improvement in treating the condition, with 40% of patients clearing all symptoms within 12 weeks. The treatment was found to be more effective than a placebo or widely used drug etanercept.
A faulty calcium channel in heart cells can cause a rare but potentially fatal heart condition called CPVT. When someone with the faulty gene exercises, adrenaline release can flood into the heart cells, causing a fatal arrhythmia.
Researchers at Johns Hopkins Medicine discovered a protein-signaling process that accelerates the work of the most frequently mutated gene in adult leukemia. A combination of two drugs targeting this process and the gene itself slowed leukemia cell growth in mice, suggesting potential for improved treatment outcomes.
Researchers unveiled innovative approaches to cancer treatment and malaria vaccination at the 2015 AAPS National Biotechnology Conference. Dual antibody-coated nanomaterials show promise in capturing circulating tumor cells, while penfluridol suppresses pancreatic tumor growth through autophagy-mediated apoptosis.
Scientists at the University of Montreal have discovered a new approach to treating amyotrophic lateral sclerosis (ALS) by targeting the immune system. The study, published in Nature Communications, found that an imbalance of the immune system can contribute to ALS and trigger motor neuron destruction.
A study of travertine deposits in the Anio Novus aqueduct revealed an actual estimate of its flow rate, significantly lower than previous estimates. The aqueduct's average water level indicates it was almost always full of water, supplying Rome with a reliable water supply that enabled urbanization during the first century AD.
A Montréal research team found that the dual-hormone artificial pancreas provides the most benefits by reducing time spent in nocturnal hypoglycaemia. The study also showed that no participant using the system experienced a nocturnal hypoglycaemia event requiring treatment.
A mother's environment around the time of conception can affect her child's lifelong risk of disease by altering the function of a specific gene. The study found that maternal nutrition, particularly in rural Gambia, impacts the methylation marks on the VTRNA2-1 gene, which influences immunity and cancer risk.