Sepsis, a life-threatening condition causing widespread inflammation and organ failure, is poorly understood despite being one of the best-known medical disorders. The Lancet Infectious Diseases Commission recommends prioritizing biomarkers, education, and public awareness to improve diagnosis and treatment.
According to a study by University of the Pacific researchers, schools are better at counting homeless students to receive federal funds but often fail to provide tailored services. The study found that increased funding led to more backpacks, school supplies, and bus vouchers than counseling or other academic support.
Researchers at MD Anderson Cancer Center identified three subsets of lung cancer with KRAS gene mutations, each with unique signaling patterns and susceptibility to different therapeutic strategies. These subsets may offer new approaches for treating lung adenocarcinoma, the most common form of lung cancer.
A study has identified molecular changes that occur in tissue after chemotherapy in ovarian cancer patients. The researchers found that these changes could be potential targets for new, more personalized drugs. The findings have the potential to advance treatments for ovarian cancer.
Research reveals FGFR1 amplification in 22.7% of small cell lung cancer tumors, implying applicability to non-small cell lung cancer treatments
Researchers from Yale-NUS, NUS and UT Austin develop a theoretical framework to understand the elastic and electronic properties of graphene. The findings provide insights into creating hybrid materials with band gaps necessary for semiconductors.
A phase I trial found a new combination of immunotherapy drugs to be safe and effective in shrinking tumors in patients with metastatic melanoma. The dual treatments, which target the immune system's 'brakes' and 'gas,' resulted in an overall response rate of 27% and median progression-free survival of 2.5 months.
Researchers successfully migrated immune cells to tumor sites in patients with mesothelin-expressing tumors. The treatment showed no major adverse events, suggesting patients tolerated it well, with T cells targeting and surviving at tumor sites for up to 28 days.
Researchers found that long-time consumption of soyfoods boosts immune response against breast tumors, reducing cancer recurrence. Genistein in soyfoods activates anti-tumor immune responses and reduces immunosuppressive mechanisms.
Researchers have found that broccoli sprout extract can protect against oral cancer in mice and has shown protective changes in the lining of the mouths of healthy human volunteers. A human clinical trial is underway to explore its potential in preventing head and neck cancer recurrence.
A new study by NYU Steinhardt found that an educational app can accelerate learning and improve phonological awareness in low-income preschoolers. The app, Learn with Homer, was effective in boosting school readiness skills, closing the 'app gap' in access to technology for disadvantaged children.
A new study by University of the Pacific researchers finds that foster youth need formal programs for financial and academic assistance to improve their college graduation rates. The study highlights the challenges faced by former foster kids in college, including limited computer skills and lack of financial support.
Research shows obesity is a key shared risk factor for cancer, diabetes, and cardiovascular disease, contributing to 20% of cancers and 58% of type 2 diabetes. Collaboration between researchers from different disciplines could lead to better understanding of how these factors drive diseases.
According to TALIS survey results, US teachers work largely in isolation, reporting less engagement in collaborative efforts. This lack of collaboration may hinder student learning and teacher development.
A new study from the University of Pennsylvania School of Medicine found that pembrolizumab, a PD-1 inhibitor, shrank or stabilized tumors in most patients with pleural mesothelioma. The medication was safe and showed promise for treating this rare and deadly form of cancer.
A gene expression model called COXEN predicts canine osteosarcoma response to doxorubicin, potentially allowing veterinary oncologists to choose the most effective drug. The approach validates human models used to predict drug response in clinical trials.