Researchers identified proteins and DNA regions binding to epigenetic changes in melanoma progression. Knocking out these proteins made the tumor less aggressive and more responsive to existing treatments.
A team of scientists created a microscope that can examine a full working battery in action, revealing how recharging leads to microscopic debris and cracks. The study aims to design cheaper and more powerful rechargeable batteries using metals like magnesium or aluminum.
A new priority program funded by the German Research Foundation will develop next-generation optogenetic tools with higher light sensitivity. The program aims to expand optogenetics' application in basic research and medicine, particularly for treating vision and hearing impairments, Parkinson's disease, and cardiac diseases.
INRS Professors Patrizio Antici and Tiago Falk have been appointed to the Global Young Academy for their groundbreaking research in health, materials science, and cultural heritage. Their work aims to develop new technologies and solutions for society's pressing challenges.
A study published in JAMA Facial Plastic Surgery found that facial rejuvenation surgery can improve perceptions of likeability, social skills, attractiveness, and femininity in women. The study measured changes in personality perception after surgical procedures, including face-lifts and eyelid surgeries.
NASA's RapidScat instrument provided data on Tropical Cyclone Joalane's surface winds, revealing that the strongest sustained winds consolidated over a 24-hour period. The cyclone intensified, developing an eye with maximum sustained winds of 92 mph/148.2 kph.
Researchers at Texas Biomedical are exploring a novel mechanism for Filovirus detection using llama antibodies, which could lead to more sensitive diagnostic tools for Marburg and Ebola viruses. The goal is to develop streamlined tests that can detect all known and emerging strains of these viruses.
The international collaboration measured lawrencium's first ionization potential with a novel technique, achieving excellent agreement with theoretical calculations that include relativistic effects. This validation confirms Lr's position in the Periodic Table and opens new perspectives for studying superheavy elements.
Engineers can now predict how complex carbon nanostructures form through a new understanding of the forces involved. By analyzing these structures, designers can create nanotube forests with desired mechanical, thermal and electrical properties, leading to breakthroughs in various industries.
Researchers at UT Southwestern Medical Center have identified a wealth of genetic diversity in pancreatic cancer, including multiple mutated genes that were previously unknown. The study also revealed potential diagnostic biomarkers and defined cases where certain drugs are selectively effective against specific mutations.
Researchers have discovered that manipulating porosity in processed foods can increase the release of salt during chewing, allowing for reduced salt content without sacrificing flavor. By controlling pore size and number, food manufacturers may be able to create lower-sodium alternatives to popular snacks.
Researchers have identified various ways that HER2-positive breast cancer tumors resist therapy and discovered a potential combination therapy to overcome multiple mechanisms of resistance. A novel combination of lapatinib and a BET bromodomain inhibitor was found to block the growth of cancer cells, making the activity of lapatinib du...
A new study from Tufts University found that diets high in glycemic load, such as those with refined grains and sugars, are associated with more weight gain. In contrast, protein-rich foods like fish, nuts, and yogurt are linked to weight loss, while dairy products with lower fat content do not seem to impact weight gain.
Researchers found that neural activity in language-sensitive brain regions in infants and toddlers with ASD was similar to normal in those who developed good language ability, but nearly absent in those with poor outcomes. The study's results have the potential to predict later language outcome by early childhood.
Researchers found a significant excess of obstetrics beds in NYC hospitals, resulting in wasted resources and estimated annual costs of $26.4 million. Reducing cesarean section rates by even a small percentage could lead to large savings and improved patient access to care.
The Milky Way's star formation rate peaked 10 billion years ago, but our sun formed about 5 billion years ago. This may have fostered the growth of our solar system's planets by enriching the galaxy with heavier elements.
Researchers at Vienna University of Technology discovered that a cloud of atoms can exhibit multiple temperatures at once. The experiment utilized a microchip to cool the gas near absolute zero, allowing scientists to measure its behavior. This breakthrough helps understand the fundamental laws of quantum physics and their relationship...
Researchers found that young sea turtles (6-18 months old) swim actively and disperse through ocean currents, reaching favorable habitats. This discovery has huge implications for understanding early sea turtle survival and behavior.
Researchers analyzed whole genomes of seven mountain gorillas, revealing genetic adaptations to small populations and a surprisingly low number of harmful genetic variations. This new understanding provides valuable insight into how apes adapt genetically to living in small populations.
Seth Bordenstein's research aims to understand the regulation of bacterial infections passed from mother to offspring. The study will test three hypotheses to pinpoint animal genes that control microbe density.
Leading cognitive scientists at Carnegie Mellon University question the lack of female contributors in a special issue of the journal Cognition. Despite having 11 women on its faculty roster, only one female author was listed among 19 authors for 12 articles.
A study found that combined sewer overflows can lead to a significant increase in emergency room visits for gastrointestinal illnesses, contaminating drinking water sources. The researchers analyzed data from three areas with combined sewer systems and found a 13% increase in ER visits after extreme precipitation events.
Scientists discovered that Lake Erie's dead zones are variable and move erratically, affecting fish distributions and catch rates. Fish like yellow perch cluster at the edges of these areas, making it essential to determine effective fishing strategies.
Researchers have found that the Ebola virus uses a protein called VP35 to remove its genetic material's protective coat, allowing it to replicate. Disrupting this process could potentially stop the spread of the disease.
A study by the University of Louisville found that children with neurological disorders experience a higher risk of flu complications, yet vaccination rates remain suboptimal. Parents and healthcare providers often have misconceptions about the vaccine's safety and effectiveness.
Researchers at the University of Texas MD Anderson Cancer Center review the potential of combining genomically targeted therapies with immune checkpoint blockade drugs to attack cancer. The approach shows promise, but more support is needed to accelerate progress and minimize side effects.
Scientists have discovered that ferromanganese crusts, up to 26 cm thick, record past climate changes in the Arctic. The crusts' slow growth rates and geochemical fingerprints of their source regions provide valuable information on ocean currents and climate conditions over millions of years.
The Ohio Supercomputer Center has dedicated the Ruby Cluster, a high-performance computing system built with HP-Intel Xeon Phi technology, to honor Ruby Dee. The cluster boasts an estimated peak performance of 144 TeraFLOPS and will support research collaboration, commercialization, and workforce development across Ohio.
The iPerform Center for Assistive Technologies aims to create software for assistive technologies, with a focus on creating software. Researchers expect to attract more industry partners and collaborate with other centers on campus.
A study published at Temple University reveals that the dispersant used in the Deepwater Horizon oil spill is more toxic to cold-water corals than the spilled oil. The researchers found that a lower concentration of dispersant was lethal to the corals, highlighting the potential risks of using these chemicals to clean up oil spills.
A recent study published in The Lancet Neurology has found that a clot-busting drug called alteplase can benefit stroke patients without increasing the risk of bleeding. Researchers analyzed over 3,000 people and discovered that patients with early tissue damage from strokes still benefit from receiving the drug.
Researchers at Scripps Research Institute have received a grant to investigate the Hippo-YAP signaling pathway in various cancers, including breast and colorectal cancer. The study aims to identify compounds targeting this pathway to combat cancer, with a focus on ultra-high-throughput screening resources.
The Genetics Society of America awarded nine young researchers for their innovative work on fruit fly models, shedding light on human genetics diseases. The winners showcased promising contributions to the field, including studies on gene expression and chromatin state in Drosophila development.
Researchers at RIT studied binary spinning black hole interactions, revealing a long-term spin dynamic that continuously flips the spin until merger. This process may affect the growth of black holes surrounded by accretion disks and alter galactic and supermassive binary black holes.
Researchers found that a neural circuit evaluates environmental variability to prompt animals to explore new locations. The circuit uses information from the animal's senses to determine predictability, triggering dopamine release and increased risk-taking behavior. This discovery could lead to better therapies for neurodegenerative an...
A study found that young children's aversion to opposite-sex peers (the 'cooties' effect) is encoded in the amygdala. As children enter puberty, interest in opposite-sex peers blooms anew, with some becoming infatuated with a member of the opposite sex.
A study of facial rejuvenation surgery finds that women who undergo certain procedures are perceived as more likeable, attractive and feminine. The study suggests that facial appearance plays a role in social perception, rooted in evolution, and may impact personality traits such as extroversion and trustworthiness.
A study by Ryan Boyd and James Pennebaker uses psychological theory to analyze Shakespeare's plays, revealing a unique psychological profile that strongly identifies him as the author of Double Falsehood. The analysis also sheds light on Theobald's character, contradicting previous accounts.
Researchers at Caltech discovered that certain bacteria in the gut are essential for producing peripheral serotonin. The study found that mice with normal gut microbes had higher levels of serotonin than those without, and that specific species of bacteria elevated serotonin levels.
A new University of Utah study found that exposure to killing and death while deployed is correlated with a 43% increased suicide risk compared to general deployment. The research suggests that seeing death and killing contributes to feelings of guilt, shame, regret, and negative self-perceptions.
The study suggests that highly acidic oceans caused the extinction event, which lasted around 10,000 years. The research provides new insights into the threat posed by modern-day ocean acidification.
Researchers at Johns Hopkins Medicine found that touch-sensing neurons integrate position and touch information as soon as it reaches the brain, challenging long-held views on how this is done. This integration enables complex sensory processing and informs efforts to improve prosthetic limbs.
A recent York University study suggests that lake and highway authorities consider adjusting road salt use protocols to protect aquatic life such as the water flea, by taking the nutritional status of the lakes into account. The study found a direct relationship between how well-fed the animals were and their sensitivity to road salt.
The NIH has awarded $11 million to develop diagnostic tools for hospital-associated pathogens, including those resistant to most antimicrobials. The goal is to provide rapid and efficient tests that can detect the presence of these bacteria in three hours or less.
A retrospective cohort study of nearly 217,000 patients with gout found that prescription rates for effective gout treatment decreased after the FDA increased prices. The study also showed significant increases in monthly total prescription bills, highlighting the negative impact of regulatory actions on access to affordable medications.
Radon levels in Pennsylvania homes have risen since 2004, coinciding with the onset of fracking. The study found higher readings in buildings near active gas wells compared to low-activity areas. Radon is a known carcinogen that can accumulate in homes without adequate ventilation, increasing lung cancer risk.
A NASA study found that small solar eruptions, like a slow-moving CME, can cause significant atmospheric loss in planets without magnetic shields. This research has implications for understanding habitability and the potential effects of solar storms on other planets.
Researchers study the Great Lakes to determine what controls the toxicity of cyanobacterial blooms, which can be deadly to humans. They found high levels of hydrogen peroxide in Lake Erie's surface waters, which may contribute to bloom toxicity.
Researchers aim to create the first complete genome sequence for dogwoods, enabling plant breeders to develop new varieties with improved traits. Citizen scientists will collect data on flowering patterns, flower color, and susceptibility to diseases.
Dr. Theresa Montini is awarding $300,000 from the National Institutes of Health to test a nicotine cessation approach in NYC homeless shelters. Her Matrix model-based treatment aims to promote self-esteem and dignity among homeless clients.
Researchers James P. Allison and Padmanee Sharma argue that combining targeted therapies with immunotherapy could be key to developing curative treatments for various cancer types, building on promising results from clinical trials.
Scientists at TGen discovered the likely cause of severe muscle weakness in six previously undiagnosed children using state-of-the-art genetic technology. The researchers identified pathogenic variants in genes such as CACNA1S, RYR1, COL6A3, and COL6A6, providing new insights into rare myopathies.
A new study suggests that non-violent video games with storytelling can have prosocial benefits, improving emotional intelligence and social skills. The research found that immersive gaming experiences foster theory of mind and empathy, which can be helpful in treating disorders like autism.
A new assay developed by researchers can identify novel drug candidates that protect kidney cells from damage, which could lead to the development of new treatments for chronic kidney disease. The system has already identified a small molecule called pyrintegrin that effectively protected rodent kidney cells.
Researchers from Carnegie Institution for Science discovered that brassinosteroids and auxin hormones work antagonistically to regulate root cell elongation, affecting the rate of root growth. This finding could lead to engineering more-efficient crops with idealized root growth and water uptake.
A new species of terror bird, Llallawavis scagliai, has been discovered with exceptionally preserved fossils revealing details about its anatomy and sensory capabilities. The study provides insights into the evolution, behavior, and ecology of this group of fossil birds.
Scientists at Cold Spring Harbor Laboratory have revised the theory of how PTEN shuts off growth signals in cells. They found that PTEN proteins travel along microtubule highways to cytoplasmic vesicles containing green signals, which are then pinched off and turned back to red through a process called endocytosis
Research suggests that inbreeding has genetically benefited mountain gorillas by eliminating deleterious variations, contributing to their survival. This discovery challenges the assumption that low genetic diversity makes these animals more susceptible to environmental changes and diseases.
Researchers at the University of Illinois have identified a new mastrevirus, SgMaV-1, infecting switchgrass in North America. The virus is closely related to known pathogens in Australia and may be transmitted by leafhoppers, posing risks to staple food crops like corn and wheat.
Erik Wambre, PhD, at Benaroya Research Institute will study T cells causing peanut allergy and analyze genes to neutralize these cells. The goal is to develop new approaches for diagnosis and treatment of food allergies.