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Science News for April 7, 2015


Inventing a 2-D liquid

Researchers at the University of Pennsylvania have developed nanoparticles that can interact with oil-water interfaces without clumping together. By measuring pressure and density, they've established universal rules governing the physics of these systems, which could lead to advances in nanomanufacturing, catalysis, and photonic devices.

SourceUniversity of Pennsylvania·JournalPhysical Review Letters·DateApr 7, 2015

UM study finds fast food just as effective for recovery as sports supplements

A new University of Montana study published in the International Journal of Sport Nutrition and Exercise Metabolism found that eating fast food after a workout can provide the same potential for muscle glycogen recovery as traditional sports supplements. The study, led by Brent Ruby, analyzed muscle biopsies and blood samples from male...

SourceThe University of Montana·JournalInternational Journal of Sport Nutrition and Exercise Metabolism·DateApr 7, 2015

Which type of sustainable rooftop technology is best in cold climates?

A new study finds that photovoltaic panels outperform green roofs and white roofs in cold Canadian climate. Green roofs are the only option to reduce both heating and cooling energy use, while photovoltaic panels demonstrate high environmental performance across all impact categories.

SourceWiley·JournalJournal of Industrial Ecology·DateApr 7, 2015
Celestron NexStar 8SE Computerized Telescope

Celestron NexStar 8SE Computerized Telescope combines portable Schmidt-Cassegrain optics with GoTo pointing for outreach nights and field campaigns.

Education and awareness key to helping physicians address elder abuse

Elder abuse affects 5-10% of seniors and is associated with hospital admissions, reduced quality of life, and death. Physicians can help prevent it by being aware of risk factors and using validated screening tools like the Elder Abuse Suspicion Index.

SourceCanadian Medical Association Journal·JournalCanadian Medical Association Journal·DateApr 7, 2015

Novel therapeutic procedure helps stroke patient recover three-dimensional vision

Researchers at Saarland University have developed a treatment regime to help stroke patients regain binocular depth perception, enabling them to perceive spatial depth and judge distances accurately. The procedure has shown promising results, with one patient returning to work as a lawyer after being cured of 'flat vision',

SourceSaarland University·JournalNeuropsychologia·DateApr 7, 2015

The rest of the brain gets in the way

A study using fMRI scans found that unnecessary brain activity hinders learning, while reduced neural connections facilitate faster skill acquisition. The researchers' novel analysis methods revealed complex brain networks and community structures that correlate with individual differences in learning rates.

SourceUniversity of Pennsylvania·JournalNature Neuroscience·DateApr 7, 2015

Simons Foundation honors UMass Amherst mathematician

HongKun Zhang will use the $100,000 award to work with colleagues in France and St. Louis on a mathematical conjecture arising in statistical mechanics. Her research aims to improve conceptual understanding of physical systems and predict their behavior.

SourceUniversity of Massachusetts Amherst·DateApr 7, 2015
SAMSUNG T9 Portable SSD 2TB

SAMSUNG T9 Portable SSD 2TB transfers large imagery and model outputs quickly between field laptops, lab workstations, and secure archives.

Into thin air and back

Researchers examined muscle physiology in deer mice from high and low-altitude habitats, revealing heritable differences in energy metabolism and muscle plasticity. Genetic changes associated with increased oxidative capacity and blood supply enabled improved fitness under hypoxic conditions.

SourceSMBE Journals (Molecular Biology and Evolution and Genome Biology and Evolution)·JournalMolecular Biology and Evolution·DateApr 7, 2015

Rates of ADHD appear to decrease at higher altitudes

Researchers found that ADHD prevalence decreases substantially at higher elevations, correlating with increased dopamine levels. The study suggests that hypobaric hypoxia, a condition caused by lower oxygen levels at high altitudes, may serve as an environmental stressor and potentially protect against the disorder.

SourceUniversity of Utah Health·JournalJournal of Attention Disorders·DateApr 7, 2015

Central signaling pathway in lymphoma can be blocked successfully

Scientists have discovered a crucial signaling pathway in diffuse large B-cell lymphoma that can be targeted with substances already in clinical development for other diseases. This finding holds promise for diagnosis, prognosis, and treatment of the disease.

SourceUniversity of Zurich·JournalJournal of Experimental Medicine·DateApr 7, 2015
Apple iPhone 17 Pro

Apple iPhone 17 Pro delivers top performance and advanced cameras for field documentation, data collection, and secure research communications.

Purging a virus from organ transplants

Scientists have discovered a molecular switch that allows human cytomegalovirus to enter dormancy or reactivate infection. By manipulating this switch with simple drugs, HCMV can be targeted with antivirals and purged from organs before transplantation.

SourceEcole Polytechnique Fédérale de Lausanne·DateApr 7, 2015

Six from CCNY named NSF Graduate Research Fellows

Six CCNY graduates have been named National Science Foundation (NSF) Graduate Research Fellows for their exceptional proposals in biology, environmental engineering, bioengineering, chemical engineering, and geochemistry. The fellowships provide annual stipends and cost-of-education allowances to support graduate study.

SourceCity College of New York·DateApr 7, 2015
Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C)

Anker Laptop Power Bank 25,000mAh (Triple 100W USB-C) keeps Macs, tablets, and meters powered during extended observing runs and remote surveys.

Obesity in children: Breastfeeding is best, but...

Recent studies show that breastfeeding significantly reduces the risk of childhood obesity, with benefits increasing with longer and more exclusive breastfeeding. However, research now needs to move beyond observational studies to provide definitive evidence.

SourceSpringer Science+Business Media·JournalCurrent Obesity Reports·DateApr 7, 2015

New, natural DNA-based drugs are safe, potent activators of immune system

MGN1703 is a single-stranded oligonucleotide-based drug that activates the human immune system without causing harmful side effects. It works by binding to toll-like receptor 9, triggering a cascade of signaling pathways that enable recognition and destruction of foreign cells.

SourceMary Ann Liebert, Inc./Genetic Engineering News·JournalNucleic Acid Therapeutics·DateApr 7, 2015
GoPro HERO13 Black

GoPro HERO13 Black records stabilized 5.3K video for instrument deployments, field notes, and outreach, even in harsh weather and underwater conditions.

Contaminants also a threat to polar bears

A recent study highlights the growing threat of environmental contaminants and plastic pollution to polar bear health, alongside climate change. The research, led by Norwegian scientists, found that exposure to these pollutants is affecting the endocrine system and reproductive system of polar bears.

SourceSpanish Foundation for Science and Technology·JournalEnvironmental Research·DateApr 7, 2015

How do single women seeking donor semen differ from cohabiting women?

A Danish study of 311 women reveals that single women seeking donor semen differ little from cohabiting women in terms of sociodemographic characteristics and attitudes toward motherhood. The study suggests that the myth surrounding single women's suitability for parenthood may be overstated.

SourceWiley·JournalActa Obstetricia Et Gynecologica Scandinavica·DateApr 7, 2015
CalDigit TS4 Thunderbolt 4 Dock

CalDigit TS4 Thunderbolt 4 Dock simplifies serious desks with 18 ports for high-speed storage, monitors, and instruments across Mac and PC setups.

New study hints at spontaneous appearance of primordial DNA

A new study by the University of Colorado Boulder and the University of Milan proposes a novel scenario for the non-biological origins of nucleic acids. The research demonstrates that the spontaneous self-assembly of short DNA fragments can drive the formation of longer polymers, potentially providing a pre-RNA route to the RNA world.

SourceUniversity of Colorado at Boulder·JournalNature Communications·DateApr 7, 2015

Sun experiences seasonal changes, new research finds

New research reveals quasi-annual variations in solar activity that can amplify or weaken solar storms, affecting Earth's atmosphere. Understanding these variations could lead to improved predictions of space weather events and mitigation strategies.

SourceNational Center for Atmospheric Research/University Corporation for Atmospheric Research·JournalNature Communications·DateApr 7, 2015

Tunneling across a tiny gap

Heat flow between materials separated by less than a nanometer occurs not via radiation or conduction, but through phonon tunneling. Researchers developed a unified framework to calculate heat transport at finite gaps, explaining how phonons can

SourceMassachusetts Institute of Technology·JournalNature Communications·DateApr 7, 2015

Leading cardiovascular societies release new guidance on use of heart pumps

Expert consensus statement provides new guidance to match right device with right patient, expanding treatment options for acutely and chronically ill cardiac patients. Percutaneous mechanical circulatory support devices offer superior circulatory support compared to medical therapy in certain cases.

SourceAmerican College of Cardiology·JournalCatheterization and Cardiovascular Interventions·DateApr 7, 2015
Apple iPad Pro 11-inch (M4)

Apple iPad Pro 11-inch (M4) runs demanding GIS, imaging, and annotation workflows on the go for surveys, briefings, and lab notebooks.

Catheter-related bloodstream infections examined in home parenteral nutrition patients

A new study published in JPEN found that using peripherally inserted central venous catheters (PICCs) for one additional infusion day per week significantly reduced the time before a first bloodstream infection. In contrast, managing tunneled vascular access devices by home care nurses increased the mean incidence of such infections.

SourceAmerican Society for Parenteral and Enteral Nutrition (A.S.P.E.N.)·JournalJournal of Parenteral and Enteral Nutrition·DateApr 7, 2015

WSU study finds cigarette warning labels may be more effective with imagery

A WSU study found that young adults learn more about the dangers of smoking when warnings are presented in images and text, leading to increased worry and discouragement from smoking. The labels used in the study emphasized negative consequences associated with lung cancer, heart disease, and stroke.

SourceWashington State University·JournalAnnals of Behavioral Medicine·DateApr 7, 2015

Complex bacterial challenge in fight against deadly amphibian disease

Researchers have made significant progress in understanding the complex relationship between bacteria and the deadly frog disease chytrid fungus. The study found that only a small proportion of bacteria inhibited all forms of the disease, highlighting the need for diverse probiotic treatments to combat its shifting targets.

SourceUniversity of Manchester·JournalApplied and Environmental Microbiology·DateApr 7, 2015

Seena Magowitz Foundation funds TGen's zebrafish studies of pancreatic cancer

Researchers at TGen are using zebrafish to accelerate investigations of pancreatic cancer, with the goal of finding therapeutics that can slow down and reverse tumor growth. The study is funded by the Seena Magowitz Foundation and aims to understand how pancreatic cancer invades local tissue and spreads to other organs.

SourceThe Translational Genomics Research Institute·DateApr 7, 2015
Sony Alpha a7 IV (Body Only)

Sony Alpha a7 IV (Body Only) delivers reliable low-light performance and rugged build for astrophotography, lab documentation, and field expeditions.

Two ancient human fossils from Laos reveal early human diversity

Researchers have discovered two ancient human fossils in Laos that show early modern humans were physically quite diverse, with one jawbone exhibiting both archaic and modern human traits. The discovery adds to the evidence that early modern humans migrated through Southeast Asia earlier than previously thought.

SourceUniversity of Illinois at Urbana-Champaign, News Bureau·JournalPLOS ONE·DateApr 7, 2015

Cost of cancer drugs varies widely based on who's paying

Uninsured cancer patients pay 2-43 times more than Medicare and private insurers for chemotherapy drugs, according to a new study. The study found significant price differences for expensive and inexpensive drugs alike.

SourceUniversity of North Carolina at Chapel Hill·JournalHealth Affairs·DateApr 7, 2015

New tool to diagnose Ebola uncovers some surprises

A new tool uncovers some surprises in diagnosing Ebola by identifying six key symptoms: contact with an infected person, diarrhea, loss of appetite, muscle pain, difficulty swallowing and absence of abdominal pain. This score can help clinicians risk-stratify patients during outbreaks.

SourceAmerican College of Emergency Physicians·JournalAnnals of Emergency Medicine·DateApr 7, 2015
Meta Quest 3 512GB

Meta Quest 3 512GB enables immersive mission planning, terrain rehearsal, and interactive STEM demos with high-resolution mixed-reality experiences.

Gotcha! Ultra-realistic robot proves there's more than 1 way to scare a fish

Researchers at NYU Tandon School of Engineering have developed a robotic predator that can spook zebrafish just as well as a real one, revealing new insights into fear and anxiety in animal populations. The robot's effectiveness was comparable to that of live red tiger oscar, but with more consistent avoidance responses.

SourceNYU Tandon School of Engineering·JournalZebrafish·DateApr 7, 2015
Apple AirPods Pro (2nd Generation, USB-C)

Apple AirPods Pro (2nd Generation, USB-C) provide clear calls and strong noise reduction for interviews, conferences, and noisy field environments.

Women, regardless of their backgrounds, seek help for the 'got to go' feeling

A large study found that most women, regardless of their background, experience urinary urgency and stress incontinence during menopause. The strongest associations with seeking care were worsening and persistence of symptoms, highlighting the importance of discussing treatment options with a healthcare provider.

SourceUniversity of California - Davis Health·JournalObstetrics and Gynecology·DateApr 7, 2015

Mortality and blood pressure directly linked to relationship quality

A new study published in the Journal of Gerontology: Psychological Sciences found that mortality and blood pressure are directly linked to relationship quality. The research revealed that wives' stress has significant implications for husbands' blood pressure, particularly in negative relationships.

SourceOxford University Press USA·DateApr 7, 2015
Aranet4 Home CO2 Monitor

Aranet4 Home CO2 Monitor tracks ventilation quality in labs, classrooms, and conference rooms with long battery life and clear e-ink readouts.

New model could help identify root cause of swallowing disorder

Researchers at the University of Missouri have established a model that identifies aging as a key factor in the development of dysphagia. Healthy aging mice exhibit symptoms of swallowing impairment similar to those seen in older adults, with slowed swallowing function and impaired tongue movement.

SourceUniversity of Missouri-Columbia·JournalDysphagia·DateApr 7, 2015

The hoo's hoo of gibbon communication

Researchers have deciphered gibbons' subtle 'hoo' calls in response to specific events like foraging and predator encounters, revealing context-specific vocal communication. The study's findings suggest that gibbon vocalisations may hold clues about the evolution of human speech.

SourceBMC (BioMed Central)·JournalBMC Evolutionary Biology·DateApr 7, 2015
Rigol DP832 Triple-Output Bench Power Supply

Rigol DP832 Triple-Output Bench Power Supply powers sensors, microcontrollers, and test circuits with programmable rails and stable outputs.

Epidemiology of HIV-1 transmitted drug resistance

A study analyzing individual virus sequences from 287 published studies found that most HIV-1 transmitted drug resistance strains arose independently in sub-Saharan Africa and south/southeast Asia. The study suggests screening for specific high-prevalence mutations could identify patients with TDR before therapy initiation.

SourcePLOS·JournalPLOS Medicine·DateApr 7, 2015

Brontosaurus is back!

A new study by palaeontologists from Portugal and the UK provides conclusive evidence that Brontosaurus is distinct from Apatosaurus, overturning over a century of research. The team applied statistical approaches to calculate differences between species and genera, revealing Brontosaurus as a unique genus.

SourcePeerJ·JournalPeerJ·DateApr 7, 2015

TSRI scientists find molecular trigger of schizophrenia-like behaviors and brain changes

Researchers at TSRI have identified a molecule, lysophosphatidic acid (LPA), that triggers schizophrenia-like symptoms in animal models, including hyperactivity, anxiety, and altered brain structure. The study provides new tools for preventing or treating psychiatric disorders such as schizophrenia, bipolar disorder, and autism.

SourceScripps Research Institute·JournalTranslational Psychiatry·DateApr 7, 2015

Carbon nanotube computing?

Researchers at Durham University and the University of São Paulo discovered a correlation between single-walled carbon nanotube concentration and computational capability in composite materials. The emerging field of 'evolution-in-materio' uses natural evolution principles to train materials to mimic electronic circuits.

SourceAmerican Institute of Physics·JournalJournal of Applied Physics·DateApr 7, 2015
Fluke 87V Industrial Digital Multimeter

Fluke 87V Industrial Digital Multimeter is a trusted meter for precise measurements during instrument integration, repairs, and field diagnostics.

Lizards are larger and retain heat longer in high-altitude habitats

Scientists at the University of Granada have confirmed Bergmann's rule for ectotherms, revealing that long-tailed lizards are larger and retain heat longer in high-altitude habitats. This study resolves decades-long debates on the mechanism behind the Bergmann clines, showing that larger animals indeed have slower cooling rates.

SourceUniversity of Granada·JournalJournal of Evolutionary Biology·DateApr 7, 2015

Easing the pain

A recent study published in PAIN found that combining morphine and nortriptyline provides better pain relief than using either drug alone, with 87% of patients experiencing significant pain reduction. The combination treatment also showed no worsening of common side effects such as constipation and dry mouth.

SourceQueen's University·JournalPain·DateApr 7, 2015

New technology making drones safer and smarter

The new technology enables drones to detect safe landing spots and execute proper landing operations even without GPS signal. The system uses computer-vision software to analyze images and identify landmarks, allowing the drone to regain stable flight and fulfill its mission autonomously.

SourceUniversity of Zurich·DateApr 7, 2015

Asbestos use in Asia poses serious health dangers

The increasing use of asbestos in Asia poses a significant threat to public health, with the potential for widespread mesothelioma and lung cancer cases. Government and non-government groups must work together to improve recognition and diagnosis of asbestos-related lung diseases.

SourceWiley·JournalRespirology·DateApr 7, 2015
Kestrel 3000 Pocket Weather Meter

Kestrel 3000 Pocket Weather Meter measures wind, temperature, and humidity in real time for site assessments, aviation checks, and safety briefings.

Bumblebees differentiate flower types when arranged horizontally but not vertically

Researchers found that bumblebees can distinguish between two visually clearly different feeder types when arranged horizontally but failed to do so when they were distributed vertically. The bees' decision-making is influenced by their natural foraging environment, where rewarding and unrewarding flowers often grow side-by-side.

SourceQueen Mary University of London·JournalBehavioral Ecology·DateApr 7, 2015

New mechanisms of 'social networking' in bacteria

Scientists deciphered bacterial communication mechanisms, revealing new ways bacteria regulate gene expression. Quorum sensing controls a variety of biologically relevant processes, and the study expands our understanding of regulation in Bacillus subtilis.

SourceUniversity of Massachusetts Amherst·JournalMolecular Microbiology·DateApr 7, 2015
DJI Air 3 (RC-N2)

DJI Air 3 (RC-N2) captures 4K mapping passes and environmental surveys with dual cameras, long flight time, and omnidirectional obstacle sensing.

Overconfidence in new technologies can influence decision-making

Research by University of Missouri professor Chris Robert found that people tend to overestimate the likelihood of new technologies' success, influencing important decisions. This phenomenon, known as the 'technology effect,' is driven by constant exposure to technology and associations with successful outcomes.

SourceUniversity of Missouri-Columbia·JournalJournal of Business and Psychology·DateApr 7, 2015

Are current dietary guidelines for sodium and potassium reasonable?

Current dietary guidelines for sodium and potassium are unfeasible, with only 0.3% of Americans meeting the World Health Organization's targets. The main issue is that sodium and potassium are found in many of the same foods, making it impossible to recommend a reduction in sodium intake while increasing potassium intake.

SourceUniversity of Washington School of Medicine/UW Medicine·JournalBMJ Open·DateApr 7, 2015

Common drug is re-engineered to improve surgery outcomes

A Northwestern University team has re-engineered a common drug to deliver nitric oxide, preventing cellular overgrowth and scarring in blood vessels during and after surgery. This modified protamine sulfate can slowly release nitric oxide, minimizing its negative effects while maintaining its function as an antidote for heparin.

SourceNorthwestern University·JournalFree Radical Biology and Medicine·DateApr 7, 2015

Future electronics based on carbon nanotubes

A team of researchers has found a way to strip out metallic carbon nanotubes from arrays using a simple, scalable procedure, leaving behind semiconducting nanotubes suitable for electronic devices. This breakthrough could lead to the development of smaller, faster, and cheaper electronic devices.

SourceAmerican Institute of Physics·JournalJournal of Applied Physics·DateApr 7, 2015
Sky & Telescope Pocket Sky Atlas, 2nd Edition

Sky & Telescope Pocket Sky Atlas, 2nd Edition is a durable star atlas for planning sessions, identifying targets, and teaching celestial navigation.

New study questions role of breast milk in obesity prevention

A new study from Cincinnati Children's Hospital Medical Center suggests that breastfeeding may not be a reliable method for preventing childhood obesity. The research highlights the complex relationship between breastfeeding and obesity, citing factors such as maternal obesity and alterations in digestive system processing.

SourceCincinnati Children's Hospital Medical Center·JournalCurrent Obesity Reports·DateApr 7, 2015

The control of Idiazabal cheese is not limited to the absence of defects

A recent study by the University of the Basque Country explores the relationship between the quality of designation of origin cheeses, such as Idiazabal, and consumer preferences. The research suggests that sensory evaluation methods need to be standardized to ensure good practices are followed in cheese production.

SourceUniversity of the Basque Country·JournalFood Control·DateApr 7, 2015
GQ GMC-500Plus Geiger Counter

GQ GMC-500Plus Geiger Counter logs beta, gamma, and X-ray levels for environmental monitoring, training labs, and safety demonstrations.

Dr. Owen Witte recognized with AACR G.H.A. Clowes Memorial Award

Dr. Owen Witte, a pioneer in human leukemias and immune disorders, received the AACR G.H.A. Clowes Memorial Award for his groundbreaking work on tyrosine kinases as drug targets. His discoveries have led to multiple approved targeted therapies, transforming patient outcomes.

SourceAmerican Association for Cancer Research·DateApr 7, 2015

More anti-inflammatory genes mean longer lifespans for mammals

A recent study by UC San Diego researchers found a correlation between CD33rSIGLEC gene copy number and maximum lifespan across 14 mammalian species. Mice lacking this gene also showed signs of accelerated aging and higher levels of reactive oxygen species.

SourceUniversity of California - San Diego·DateApr 7, 2015

Swimming algae offer Penn researchers insights into living fluid dynamics

Scientists are studying Chlamydomonas reinhardtii to understand the behavior of living fluids, which could lead to new treatments for lung diseases like cystic fibrosis. The research team discovered that the algae changes its swim pattern dramatically in elastic fluids, which possess both liquid and solid-like properties.

SourceUniversity of Pennsylvania·DateApr 7, 2015
Apple MacBook Pro 14-inch (M4 Pro)

Apple MacBook Pro 14-inch (M4 Pro) powers local ML workloads, large datasets, and multi-display analysis for field and lab teams.

New study reveals mixed picture on the effectiveness of Viagra and related drugs

A new study from The University of Manchester found that Viagra and similar drugs do not completely cure impotence in older men, with many still expressing concern over their sex lives. Despite positive effects on sexual activity, users reported higher levels of dissatisfaction with relationships and overall sexual function.

SourceUniversity of Manchester·JournalInternational Journal of Impotence Research·DateApr 7, 2015

Defect found in pancreatic cells could lead to new diabetes treatment

Researchers at Columbia University Irving Medical Center have found a defect in pancreatic cells that can lead to high blood sugar levels and impaired glucose balance. An experimental drug called Rycal has been shown to stop the leaky channels and normalize glucose levels in mouse models.

SourceColumbia University Irving Medical Center·JournalJournal of Clinical Investigation·DateApr 7, 2015

Gut immune system identified as a new and effective target in treating diabetes

Research suggests that targeting the gut immune system with a commonly used anti-inflammatory drug may be an effective way to treat insulin resistance and lower blood sugar levels in humans. The study found that mice fed a high-fat diet had larger amounts of pro-inflammatory immune cells in their bowels, leading to insulin resistance.

SourceUniversity Health Network·JournalCell Metabolism·DateApr 7, 2015
Nikon Monarch 5 8x42 Binoculars

Nikon Monarch 5 8x42 Binoculars deliver bright, sharp views for wildlife surveys, eclipse chases, and quick star-field scans at dark sites.

Anesthetic gases raise Earth's temperature (a little) while you sleep

Concentrations of anesthetics desflurane, isoflurane, and sevoflurane have been rising globally, making a small contribution to climate change. The gases are potent greenhouse-gas effects, with one kilogram of desflurane equivalent to 2,500 kilograms of carbon dioxide.

SourceAmerican Geophysical Union·JournalGeophysical Research Letters·DateApr 7, 2015

Why daring to compare online prices pays off offline

A Concordia University study found that shoppers use online prices as reference points when making purchases offline. Offline retailers should focus on prices associated with highly rated online retailers to increase their impact on in-store price evaluations.

SourceConcordia University·JournalJournal of Retailing and Consumer Services·DateApr 7, 2015

Gene variant and environment can boost severity of respiratory syncytial virus

A genetic mutation combined with an urban environment increases the risk of severe respiratory syncytial virus (RSV) disease in children. Children from urban middle-class families were eight times more likely to be hospitalized, a risk similar to extremely premature babies.

SourceVanderbilt University Medical Center·JournalJournal of Clinical Investigation·DateApr 7, 2015