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Science News for December 13, 2015


Cancer cell collaborators smooth the way for cancer cells to metastasize

Researchers at Vanderbilt University have discovered that cancer-associated fibroblasts (CAFs) rearrange the extracellular matrix into parallel fibers of fibronectin, creating a road for migrating cancer cells to follow. This allows CAFs to exert traction forces on the ECM, enabling cancer cells to move in a single direction.

SourceAmerican Society for Cell Biology·DateDec 13, 2015