A seven-year study found that responsive direct cortical stimulation significantly reduced seizures by up to 60% and improved quality of life. The Long-Term Treatment Study showed that 84% of participants experienced some improvement, with 16% being seizure-free for at least three months.
Researchers discovered that increased levels of retinoic acid reduce blood cell production, while lower levels increase it by 300%. This finding supports the need for pregnant women to limit their vitamin A intake. The study also contributes to the development of artificial blood stem cells for patients with blood disorders.
The UC Davis project, part of the FAANG Initiative, focuses on functional genomics of chicken, cow, and pig genomes to better understand gene regulation and complex traits. This research aims to improve agricultural productivity and sustainability by identifying key genetic elements influencing animal development and behavior.
Researchers at Aarhus University have made a comprehensive description of the proteins in gila lizard venom, which could lead to the development of new types of drugs. The study identified nineteen new proteins with potential pharmaceutical applications, including treatments for blood clots and pain relief.
A common antibiotic, clarithromycin, has shown potential as an anti-cancer agent when used in combination with other drugs. Low- and middle-income countries may play a key role in developing this treatment, which could lead to improved patient outcomes.
A new open-source database, Fossil Calibration Database, has been launched to help researchers accurately estimate the origins of all species. The database synthesizes data from the fossil record with molecular evidence, enabling 'molecular dating' studies.
Three Austrian men have undergone a new technique called 'bionic reconstruction', enabling them to use a robotic prosthetic hand controlled by their mind. The technique restored a high level of function, aiding in activities of daily living and improving quality of life.
A large Australian study confirms that up to two-thirds of smokers will die from their habit if they continue smoking. The study found that smokers have a three-fold risk of premature death compared to non-smokers.
A study by Alfred Wegener Institute finds that ocean acidification negatively impacts diatom growth in the Southern Ocean, particularly under changing light conditions. Diatoms' biomass production could be drastically reduced in future scenarios with more acidic water.
Jonathan Timcheck, an Ohio State Honors student, has been awarded a Churchill Scholarship to study applied math at the University of Cambridge. He will leverage his experience with GPUs on OSC's Oakley Cluster to explore cutting-edge mathematical methods for analyzing large datasets.
A new pretreatment process called Co-solvent Enhanced Lignocellulosic Fractionation (CELF) reduces the need for enzymes in biofuel production by up to 90%, cutting costs by 30% or more. This technology also extracts up to 90% of lignin from biomass, paving the way for additional high-value chemicals and fuels.
Researchers identified a strong association between an East-Asian specific mutation and increased risk of wet AMD, highlighting the importance of HDL metabolism in the disease's pathogenesis. The study also uncovered three new genes linked to AMD for the first time.
Researchers have identified a region in the human genome associated with peanut allergy in U.S. children, suggesting that genes may contribute to its development. The study also found evidence of epigenetic changes that may influence whether those with genetic susceptibility develop the allergy.
Recent studies by McMaster University researchers found that preventing weight gain is challenging for all ages, while keeping lost weight off is also tough. Small weight losses, however, can have a positive impact on health.
Researchers at Johns Hopkins Medicine have discovered a genetic pathway that regulates thousands of genes and may fuel cancer cell growth. Blocking this pathway with the experimental drug selumetinib led to reduced tumor growth and increased cell death, offering new hope for aggressive pediatric brain cancer treatment.
A study by Bernhard Ganss and colleagues found that amelotin is essential for enamel mineralization and maturation. Ammelotin-deficient mice exhibited weak incisor-edge enamel that fractured and chipped, with delayed enamel mineralization and retention of organic matrix.
Researchers develop cubic nanoantennas made of insulating materials, overcoming heating and fabrication challenges, enabling applications in biomedicine, nanolasers, and photovoltaics. The antennas have the potential to measure food safety, identify pollutants, diagnose cancer, and transmit data with ultrafast processing.
A study analyzed lung cancer incidence and screening trends, finding a decline in the proportion of patients meeting high-risk screening criteria. The decline indicates an increasing number of patients with lung cancer would not have been candidates for screening.
Polyculturalism rejects traditional models of cultural understanding, instead viewing cultures as networks. It offers new ways to select and train employees for culturally diverse roles and provides insight into how cultures change through intercultural knowledge and relationships.
The discovery of a new turtle genus in Wyoming provides insight into how animals may respond to future climate change. Modern-day turtles may struggle to migrate northward due to habitat loss and human pressures, leading to some species' potential extinction.
A comprehensive, population-based regional health care management program for men with prostate cancer has led to improved outcomes. The program includes safety-net screening programs, improved surgical procedures, and enhanced drug management, resulting in lower rates of blood loss and osteoporosis-related complications.
A genome-wide association study identified a genetic risk area on chromosome 6 linked to peanut allergy in US children of European descent. The study found two closely linked genes, HLA-DR and HLA-DQ, associated with epigenetic changes that may contribute to the development of peanut allergy.
Filipinos who move to Canada are diagnosed with breast cancer at a younger age than women from other parts of East Asia or Caucasians. They are also more likely to be diagnosed with a more aggressive form of cancer and undergo mastectomies.
A new study in JAMA found that patients taking nonsteroidal anti-inflammatory drugs (NSAIDs) along with anticoagulant medications after a heart attack are at higher risk for bleeding and cardiovascular events. The research suggests that there is no safe window for concomitant NSAID use, even short-term treatment.
Researchers found that teen girls from rural areas were more likely to have undiagnosed asthma, with a higher rate of depression among asthmatic teens. The study suggests that depression can be a barrier to diagnosis and treatment of the disease, making it essential to address this issue.
Three UK-based research projects, led by Newcastle University, University of Bristol, and University of Warwick, aim to improve patient lives with assistive devices. The projects focus on developing prosthetic hands with sensory feedback and wearable soft robotics for independent living.
A new test from MIT researchers uses a simple paper strip to rapidly diagnose Ebola and other viral hemorrhagic fevers, such as yellow fever and dengue fever. The device takes about 10 minutes to produce results, allowing for quicker triage and isolation of patients.
The study reveals that nature-based tourism in protected areas is a significant economic driver, with an estimated annual value of $600 billion. This far surpasses the current spending on safeguarding these sites, which amounts to less than $10 billion annually.
A new study published in Molecular Cancer Therapeutics shows that a low percentage of androgen-receptor-positive cells in triple-negative breast cancer cells can benefit from anti-androgen therapies. This finding may lead to a larger pool of patients eligible for targeted cancer therapy.
A study of 210 primary care resident physicians found they rarely perform alcohol screening and brief intervention, despite its effectiveness in detecting and reducing unhealthy alcohol use. The researchers suggest that medical school curricula focus on binge drinking rather than chronic dependence.
Researchers found that schizophrenia gene loci are linked to regions called human accelerated regions (HARs) in the genome, which control gene expression. These HAR-associated loci play a key role in regulating genes linked to schizophrenia, particularly those related to neurotransmitter GABA and brain development.
A new open-source resource, Fossil Calibration Database, provides carefully vetted fossil data to calibrate molecular clocks and reveal the ages of plant and animal groups. The database addresses the issue of improper use of fossil record data in 'divergence dating,' a field crucial for understanding biodiversity origins.
India's Whistle Blowers Protection Act 2011 is criticized for lacking specific criminal penalties and civil protections for whistleblowers. Despite this, organizations like Medileaks offer a platform for doctors to share information about malpractices in medicine.
Scientists estimate that about 22,000 tons of phosphorus-rich Saharan dust cross the Atlantic Ocean annually, replenishing depleted Amazon soils. This vital nutrient plays a crucial role in maintaining the Amazon ecosystem.
Researchers have identified potential targets for precision drugs that exploit cancer cells' inherent weaknesses in DNA repair systems. This discovery could lead to personalized medicine and potentially save thousands of cancer patients from chemotherapy's horrible side effects.
New satellite-based estimate reveals phosphorus transport from Saharan Desert to Amazon rainforest over multiple years. Researchers also investigate human and robotic missions to the Moon, potentially uncovering solar system origins.
A new TGen study finds targeting stroma surrounding cancer cells can improve treatments and extend patient survival in pancreatic cancer patients. High levels of stroma correlate with poor patient survival, with median survival rates ranging from 9-24 months depending on hyaluronan and collagen levels.
Researchers found that having too many food choices increases the obesity problem, as offspring tend to eat more when given a choice between high-fat and low-fat diets. In contrast, those on a low-fat diet showed no negative impacts, but had higher energy expenditure.
In a study, 221 college students observed bullying in an online chat room and often judged the abuser indirectly by giving them bad marks or reviews later. Only 10% of students directly intervened, but many expressed regret at not doing so afterwards.
A study published in Critical Care Medicine defines the prevalence, associated factors, and time course of vasospasm in children with moderate to severe traumatic brain injury. The study found that children with higher Injury Severity Scores, fever at admission, and lower Glasgow Coma scores were at increased risk of developing vasospasm.
A study by McGill researchers found that Mandarin-speakers are more likely to interpret emotions through tone of voice, whereas English-language speakers rely on facial expressions. This cultural difference is rooted in the limited eye contact and restrained facial expressions typical of East Asian cultures.
A 10-year decline in perception of marijuana risk is reported in a study by Columbia University's Mailman School of Public Health. Women over 50, non-white individuals, and those with lower incomes are more likely to perceive cannabis use as risky.
Researchers are developing dissolvable microneedle patches that can provide protection against the poliovirus in humans. The patches, about an inch square, contain 100 vaccine-filled needles and can be applied by minimally-trained personnel, facilitating their use in remote areas.
Asphaltene analysis takes a giant step with the development of an indirect method that detects and measures particles as small as 100 nanometers. This technique can accurately quantify asphaltene precipitation and account for water presence, offering valuable insights into preventing clogs in oil production lines.
Tropical Cyclone 14S formed on February 21 in the Southern Indian Ocean, slowly organizing and consolidating. The storm intensified to 35 knots with strong thunderstorms circling its center, forecasters predict it will intensify further over the next three days
A study suggests that Republicans and Independents are more likely to disapprove of lenient neurolaw reforms, while Democrats support equally across framing conditions. This finding underscores the need for careful public presentation of neuroscience in law to maintain a non-polarizing stance.
A study found that taking a pre-exercise supplement of omega-3 PCSO-524, derived from the New Zealand green-lipped mussel, has significant positive effects on post-exercise muscle damage. The subjects experienced less muscle soreness, pain, strength loss, fatigue, and inflammatory proteins in their bloodstreams.
Researchers identified a genetic variation associated with increased risk and severity of peripheral neuropathy in young leukemia patients treated with vincristine. The high-risk CEP72 variant may allow for reduced vincristine doses without compromising cancer treatment efficacy.
A study found that a gene variant is associated with a higher incidence and severity of peripheral neuropathy in children treated with vincristine, a widely used anticancer agent. The variant, CEP72, was linked to an increased risk of nerve damage and pain in patients receiving vincristine treatment.
A recent study published in JNCI: Journal of the National Cancer Institute found that tumor location in colorectal cancer may influence survival. Patients with left-sided primary tumors had better survival outcomes than those with right-sided tumors, suggesting potential differences in gene expression patterns and cancer biology.
A study found that nearly half of patients with mental illness and a third of those with diabetes were not advised on dietary changes or physical activity. Health care providers may be missing opportunities to counsel high-risk patients about lifestyle modifications.
A comprehensive review of hormone therapy in transgender adults has found no significant increase in cancer risk despite previous concerns. The study, published in the Journal of Clinical and Translational Endocrinology, provides reassurance for individuals requiring hormone treatments, reducing anxiety and increasing access to care.
A new study by Yale University found that younger women with heart disease symptoms often delay seeking medical care, citing fears of false alarms. The research highlights the need for education and improved response strategies to empower these women to recognize early symptoms and seek prompt care.
Researchers at Universitat Autonoma de Barcelona have developed a technology to recover energy from wastewater using MEC, producing hydrogen with high efficiency and low voltage. The system demonstrated excellent results in hydrogen production and energy recovery, opening up potential for industrial-scale development.
Researchers found that pregnant lemur moms carrying boys produce simpler scents with fewer odor compounds compared to those carrying girls. The change in scent patterns correlates with changes in blood hormone levels. The study provides the first evidence of a pregnant mother's scent differing depending on the sex of her baby.
A new electrolyte for lithium batteries eliminates dendrites while maintaining high efficiencies and current densities. The discovery enables the development of powerful next-generation rechargeable batteries with improved safety and cost-effectiveness.
Tropical Cyclone Marcia caused significant flooding and damage in eastern Queensland with rainfall totals reaching up to 300-350mm. The merged precipitation analysis from NASA's Goddard Space Flight Center indicates heaviest rainfall areas were off-shore from Lismore, Byron Bay, and Mackay.
A new molecule, endosialin, on hepatic stellate cells drives liver fibrosis by activating these cells. However, its absence improved the regenerative capacity of remaining liver cells without proliferating them. This finding helps understand how liver fibrosis develops and may lead to treatments for other diseases.
Researchers discovered a skin test that can detect abnormal proteins associated with Alzheimer's and Parkinson's diseases. The study used skin biopsies to compare patients' protein levels, revealing seven times higher tau protein levels for those with both conditions.
A clinical trial at UTHealth investigates the use of a physician-monitored app to encourage minority stroke patients to lose weight and manage risk factors. The study aims to close the racial disparities gap in stroke care, with patients randomized to usual care or the app group.
Researchers at Georgia Institute of Technology found that animals and humans have similar lash lengths, which control airflow around the eye. The ideal ratio is one-third the eye width, reducing dust and increasing moisture retention.
The Pew Charitable Trusts has named five distinguished scientists and conservationists from Canada, Australia, Russia, and the UK as 2015 recipients of the Pew fellowship in marine conservation. They will conduct research projects addressing key ocean conservation challenges including bycatch reduction and coral reef protection.
A recent study by UC Berkeley professor Michael Manga found that geysers erupt periodically due to underground loops and side-chambers that trap steam bubbles. The study suggests that these underground features heat the water column above, eventually leading to sudden boiling and pressure release.
A new study has uncovered seven different species of crocodiles co-existing in the same place and time, filling gaps in understanding the Amazon's rich biodiversity. The research suggests that a peak in mollusk diversity was correlated with the rise of 'durophagous' crocodiles, which went extinct when the mega-wetlands transformed.
Researchers at Tel Aviv University have developed a groundbreaking strategy to stop brain tumor cell proliferation with targeted nanoparticles. The therapy uses RNA genetic interference to silence key proteins involved in cell division, resulting in promising survival rates for mouse models.
Researchers at UGA have discovered a new small molecule drug that may serve as a treatment against multi-drug resistant tuberculosis. The compound works by interrupting the production of RNA, rendering the bacterium incapable of reproducing and spreading infection.
Reversing international normalized ratio (INR) below 1.3 within 4 hours and maintaining systolic blood pressure less than 160 mm Hg at 4 hours were associated with lower rates of hematoma enlargement. Resuming anticoagulant therapy was linked to a lower risk of ischemic events without increased bleeding complications.
Researchers at McGill University found that visual cues are crucial in recognizing emotions conveyed by music, whereas speech relies on acoustic cues. In their study, participants identified emotions better with video and audio combined compared to just audio or speech alone.
A NASA satellite has quantified in three dimensions how much dust makes its trans-Atlantic journey from the Sahara to the Amazon rain forest. An estimated 22,000 tons of phosphorus-rich Saharan dust are carried across the ocean each year, equivalent to about the same amount lost from rain and flooding.
Scientists at Johns Hopkins University have developed a method to control individual vortices in nanowires, trapping them and maintaining resistance-free current in superconductors. This breakthrough has the potential to enhance the performance of devices such as MRI scanners, particle accelerators, and future quantum computers.
Research at Mayo Clinic found that a decline in smoking rates may lead to fewer people qualifying for early detection of lung cancer through low-dose CT scans. As smokers quit earlier, more patients are diagnosed at a later stage, increasing mortality.
A new platform developed by UCLA bioengineers uses nanotechnology-enhanced medications and AI-driven analysis to create safer and more effective treatments for drug-resistant tumors. The approach, called Feedback System Control.II, has been shown to outperform traditional combination therapies.
A study published in The BMJ found that older patients who stayed in the hospital for less than 10 days after a hip fracture were more likely to die. The research analyzed data from 116,111 Swedish residents and showed that shorter hospital stays increased the risk of death.
Researchers at Uppsala University discovered that Moringa seed protein can be used to separate different materials from water, a process important in mining industries. The study found that the optimal amount of seeds needed varies depending on the material, allowing for more efficient separation.
A new study by the HIV Prevention Trials Network found that financial incentives had no significant overall impact on achieving viral suppression among HIV-positive patients. However, specific clinical settings such as hospital-based clinics and those with lower patient engagement saw enhanced viral suppression rates. The study also sh...
A unique comet, not part of a known family, survives its trip to within 2.2 million miles of the sun's surface. This is one of the few instances where a comet has been observed and recorded by SOHO in recent years.
Researchers at the University of Huddersfield have developed a new metrology system to detect tiny defects in thin films, crucial for printed electronics and solar panels. The NanoMend project aims to reduce cost and increase reliability of flexible PV cells, paving the way for wider adoption of renewable energy.
Researchers found that garlic extract's allicin component inhibits bacterial growth and kills certain plant pathogens, potentially offering a new treatment option for people with cystic fibrosis. The study suggests using allicin-containing remedies in combination with existing antibiotics to treat life-threatening lung infections.
Princeton scientists discovered that foam significantly dampens liquid sloshing by absorbing energy through friction with container walls. The team's research has applications beyond breakfast beverages, including safer transport of hazardous liquids.
A Cancer Research UK study found that serous ovarian cancers with diverse genetic profiles are more likely to become resistant to chemotherapy and recur. This variability affects the prognosis of patients with these tumors, leading to earlier deaths compared to those with less varied tumors.
An international team analyzed 49 fungal genomes, revealing that key genome adaptation enabling symbiosis evolved independently in numerous lines of fungi. The study provides crucial information on how symbiosis between fungi and trees evolved, enabling scientists to improve prediction of reaction to environmental modifications.
A new study published in Diabetologia shows that eating a high energy breakfast and a low energy dinner improves blood sugar control for individuals with type 2 diabetes. The study found significant reductions in post-meal glucose levels and insulin levels when participants followed the high-energy breakfast and low-energy dinner diet.
A University of Missouri researcher found that even if one spouse stops driving, the other is less likely to work or volunteer. This decline in activity can occur even when the other partner can still drive. Planning for alternative transportation options is crucial to minimize negative consequences.
A new study from Florida Institute of Technology finds that ocean warming has played a significant role in the decline of iconic elkhorn and staghorn corals. The research suggests that curbing greenhouse gas emissions could support the recovery of these critical reef-building corals.
A senior doctor's interviews reveal widespread irrational drug prescribing, kickbacks for referrals, and unnecessary investigations in India's private healthcare sector. The system largely treats patients as revenue generators, without rationality or medical logic.
A team of researchers found that sea levels rose by an average of four inches along the Northeast Coast from New York to Newfoundland, causing flooding independent of hurricanes or winter storms. The extreme increase was linked to changes in ocean circulation and the North Atlantic Oscillation.