Researchers at University of Wisconsin-Madison have developed a new approach to structuring catalysts, using nano cage structures to achieve more potent chemical reactions with less material. The discovery offers a pathway for industries to wean themselves off platinum, a scarce and expensive metal.
Researchers found that personalized ads showing only one item from a consumer's browsing history are more effective than those showing all items. Consumers reject ads due to privacy concerns and discomfort with intrusiveness if retailers lack trust with customers.
A major study of over 30,000 women shows that aromatase inhibitors substantially reduce the risk of death from ER-positive breast cancer. Taking aromatase inhibitors for five years reduces the risk of death by 40% compared to tamoxifen.
A new technique has been developed to create tens of thousands of precisely guided probes covering an organism's entire genome for less than $100 in supplies. This enables genetic screening potentially accessible to organisms less well studied, facilitating targeted gene therapy and disease discovery.
The University of Delaware research team aims to improve solar cells and medical imaging by changing the color of low-energy light into higher-energy colors. Their novel approach could lead to a significant boost in solar energy harvesting, with predicted efficiencies of up to 30%.
A new library construction method allows simultaneous generation of up to 12 size-selected long mate pair libraries with reduced DNA input, time, and cost. This approach improves the likelihood of achieving high-quality genome assemblies, particularly for complex genomes.
A study published in JAMA Oncology found that chemotherapy was associated with worse quality of life near death for patients who could still perform many life functions. The researchers concluded that chemotherapy use may be unnecessary and potentially harmful for patients with progressive metastatic disease.
Research published in BMJ Open found that successful aging is associated with harmful drinking among older adults. Analysis of over 9000 responses from the English Longitudinal Survey of Ageing showed that higher income, better health, and social activity levels are linked to increased risk of hazardous drinking.
Researchers have developed a new fabrication technique to produce ultra-thin hollow nanocages with platinum walls, which can increase the utilization efficiency of the metal by up to seven times. The new structures can use smaller amounts of platinum, making fuel cells more economically viable.
Researchers have identified new genetic markers for mosquito resistance to insecticides, which could improve its detection in the field. The study also found that mutations affecting detoxification enzymes can increase the biodegradation of insecticides in resistant mosquitoes.
Researchers from Scripps Institution of Oceanography accurately mapped the 7.8-magnitude Nepal earthquake's movement, revealing a three-stage rupture process that poses significant seismic risks to the region. The study will serve as an important benchmark for understanding future seismic risks in the Himalayan region.
The University of Montana's Sunburst Sensors won a $1.5 million XPRIZE for developing an affordable and accurate pH sensor to measure ocean chemistry, recognizing efforts to combat ocean acidification. The company, founded by UM professor Mike DeGrandpre, employed 9 people at the time of the win.
Researchers have developed a new drug, CCT245737, that blocks cancer's escape route from chemotherapy, boosting its effectiveness in treating lung and pancreatic cancers. The drug, a CHK1 inhibitor, demonstrates significant anti-cancer activity when combined with chemotherapy in mice.
Postdoctoral researcher Stephen Wu's discovery challenges prevailing ideas of generating spin current from insulators. He found that a paramagnetic material can sustain a strong spin current without the need for a ferromagnetic material.
Two classes of inexpensive generic drugs, aromatase inhibitors and bisphosphonates, have been shown to improve survival prospects for postmenopausal women with early breast cancer. The combination of the two types of drug may also increase benefits while decreasing some side-effects.
Researchers at University of California, San Diego School of Medicine discovered a protein's critical role in developing and progressing acute myeloid leukemia. Blocking this molecule leads to a profound inhibition of leukemia growth, offering a novel target for better treating AML.
A new study has found that biomarkers, specifically phosphatidylethanol (PEth), are significantly higher in binge drinkers than moderate drinkers. PEth levels were positively correlated with the number of drinks consumed and self-assessment survey scores.
Tropical Storm Felicia formed over 400 miles southwest of Baja California's southern tip on July 23, 2015. The storm strengthened into a tropical storm near latitude 19.1 North, longitude 114.9 West, with maximum sustained winds near 40 mph.
A new Penn study found that internal medicine residents are twice as likely to prescribe expensive brand-name statins when supervised by senior physicians who also use them. The study's findings represent an opportunity to improve value in healthcare spending and highlight the importance of redesigning graduate medical education.
Researchers developed a high-throughput screening method to characterize and select multipotent cells from adipose-derived stromal cells (hASCs) using flow cytometry. This approach can identify specific cell types advantageous for regenerative medicine and tissue engineering applications.
The new fibers have a unique structure that allows for reversible stretching without increasing electrical resistance. They enable the creation of artificial muscles, capacitors, and strain sensors with improved performance and durability.
A recent study by the University of California - Davis found that algae concentrations are key to maintaining Lake Tahoe's iconic blue color, contradicting previous assumptions about the relationship between clarity and blueness. The report also highlights improvements in water clarity and climate change impacts on the lake.
Researchers developed a new material that mimics the structure of coral, a natural adsorbent of heavy metals, and found it could remove around 2.5 times more mercury from water than traditional aluminium oxide nanoparticles. The synthetic coral-like material has potential applications in environmental remediation.
Researchers have identified a gene associated with susceptibility to adolescent idiopathic scoliosis. The BNC2 gene is linked to increased expression of protein BNC2, which regulates YY1. Studies found that the gene variation leads to higher BNC2 production in genes with the variant, contributing to the development of scoliosis.
A multi-institutional team of researchers has identified an apparently successful treatment for a genetic immune disorder that causes a multitude of health problems. The FDA-approved drug abatacept was tested on a small group of patients, resulting in improved lung function and reduced autoimmunity.
A new study by Trinity College Dublin found that post-separation contact between fathers and their children can lead to the continued abuse of women and children. The research highlights the need for support services to prioritize the safety and wellbeing of children in these situations.
Researchers found that body fat can send signals to the brain, affecting its regulation of energy balance and stress responses. This discovery sheds new light on the relationship between stress, obesity, and metabolism.
Researchers have developed a genetic test that analyzes tumor sensitivity to radiation therapy, with findings suggesting metastatic colon tumors are more resistant to radiation than primary tumors. The study suggests personalizing radiation therapy for patients may be possible through this test.
Researchers have pinpointed the brain region responsible for unifying double vision, a process crucial for tasks such as aiming and catching objects. This finding may lead to new treatments for amblyopia, a condition where the brain favors one eye over the other.
A new workshop report from the American Institute of Biological Sciences (AIBS) identifies key barriers to complex data integration and offers recommendations for the research community. The report highlights impediments, technical problems, and crosscutting issues related to integrating data.
Researchers found a molecular clue to aging in transparent roundworm C. elegans, discovering that adult cells begin their downhill slide when an animal reaches reproductive maturity. The study suggests that a genetic switch is responsible for turning off cell stress responses, starting the decline of adult animals.
The Scripps Research Institute has been awarded $4.5 million in grants from the Bill & Melinda Gates Foundation to support HIV vaccine development. The new funding will enable scientists to screen immunogens and vaccines with high likelihood of success.
Researchers found that US health care providers perceive South Asians as being more reluctant to report pain and seek medications. This is partly due to cultural differences in medical practice in South Asia, where patients are often not asked about their pain and may be given low-dose pain medications after surgeries.
The new tool, MAGI, enables users to search, visualize, and annotate large public cancer genetics datasets, including data from The Cancer Genome Atlas project. Users can also upload their own data and compare findings to those in the larger databases.
Mayo researchers found that class II HDAC inhibitors signal through a newly discovered pathway to promote synergy with chemotherapy treatment in anaplastic thyroid cancer. The study identified vorinostat and belinostat as effective agents, which can increase activity of RhoB, a tumor suppressor and stimulate cell death.
North Carolina State University researchers have developed a way to significantly enhance wireless power transfer efficiency using magnetic field enhancement. The method uses a copper loop as a simple magnetic resonance field enhancer (MRFE), boosting transfer efficiency by at least 100% compared to air alone.
A new database, Histone Antibody Specificity Database, has been launched to improve the accuracy of histone antibodies used in epigenetics research. The database provides validated test results for over 100 commonly used antibodies, allowing researchers to select reliable options for their experiments.
A new study using ancient DNA and paleoclimate data found that rapid warming events played a greater role in the extinction of megafauna than human activity. The researchers analyzed DNA records over 50,000 years and compared them to climate event records from Greenland ice cores.
University of Pittsburgh professor Jeremy Levy has been awarded a $3 million grant to pursue research in reconfigurable nanoelectronics at oxide interfaces. The grant aims to merge two fields: semiconductor nanoelectronics and complex oxides, which hold promise for future applications including data storage and medical imaging.
Researchers found that abrupt climate changes during the Holocene epoch affected ancient societies, leading to wetter conditions compared to recent times. The study's high-resolution peat record revealed transitions in major civilizations coinciding with episodes of high atmospheric dust.
Researchers discovered that female stink bugs change the color of their eggs depending on the surrounding light environment. The darker-colored eggs, which are not darkened by melanin but a previously unknown pigment, offer protection against UV radiation when laid on top of leaves.
Researchers at Children's Hospital Los Angeles have shown improved outcomes in using stem cell transplantation to treat juvenile myelomonocytic leukemia (JMML), a rare form of chronic blood cancer. The study found that half of patients can be cured from their disease, and a potential standard conditioning regimen has been identified.
The ASBMB's Minority Affairs Committee has received a $500,000 NSF grant to support its Interactive Mentoring Activities for Grantsmanship Enhancement (IMAGE) program. The program aims to promote diversity in the scientific workforce by providing grantsmanship skills and career-development strategies to postdoctoral fellows and early-c...
Researchers found that lack of confidence, physical and mental impairments, and environmental factors hinder people with MS from engaging in meaningful activities. Building confidence is crucial to overcome these barriers and promote healthy behaviors.
Researchers develop a new method to create highly stretchable conductors by aligning carbon nanotubes with rubber cores, resulting in an impressive 1000% stretch-to-conductivity ratio. This innovation has significant implications for future medical devices, optical elements, and robotics.
Researchers at the University of Leicester and CNRS have observed the growth of free nanoparticles in helium gas, revealing new information about their structure. The study found that nanoparticles grow by clustering together under increasing pressure, similar to decaffeination processes.
NASA's Aqua satellite captured infrared data showing cloud top temperatures as cold as -63F/-53C on July 23, indicating potential heavy rainfall. The tropical depression is moving away from the Philippines in a north-northeasterly direction with maximum sustained winds near 25 knots.
Researchers at Sanford Burnham Prebys Medical Discovery Institute have discovered a new way to improve liver cancer treatment by blocking the activity of the lymphotoxin-beta receptor. The approach, which combines drugs currently in clinical trials with those targeting oncogene signals, may lead to improved patient outcomes.
The University of Montana research team, led by Sarj Patel and Tom Rau, will conduct expanded testing on biomarkers for traumatic brain injury. They aim to clinically validate their research and explore chronic traumatic encephalopathy.
A study found that certain combinations of gut bacteria, such as those from the Porphyromonadaceae and Lachnospiraceae families, resist colonization by C. difficile in mice. The researchers developed a computer model that accurately predicted C. difficile's success rate for other mice based on their gut microbiome composition.
Researchers developed a web tool to estimate the impact of genetic modification of mice, which can complicate biomedical research interpretation. The tool aids in explaining controversies and improving translation from lab animals to humans.
Researchers found that ethoxzolamide inhibits TB's ability to detect acidic environments, effectively blinding the bacterium and allowing the immune system to attack. This compound could help shorten treatment duration and slow the emergence of drug resistance in TB.
A new University of Virginia study confirms that Americans' conscious and unconscious biases against lesbian women and gay men are decreasing across all demographic groups. The study found that implicit bias decreased by 13% over seven years, while explicit bias decreased twice as much.
The American Geophysical Union awards top honors to journalists Andrew Revkin, Douglas Fox, and Sandi Doughton for their exceptional science reporting. Revkin receives the Robert C. Cowen Award for his climate change coverage, while Fox wins the Walter Sullivan Award for his story on dust's impact on drought in the US West.
A study published in Scientific Reports reveals that roosters follow a systematic rule based on social ranking to determine the order of crowing. Dominant birds take priority to announce the break of dawn, while subordinate birds wait patiently for their turn.
Researchers investigate granitic rocks in El Capitan using field mapping, rock climbing, and geochemical analyses. They found no systematic patterns in rock composition, challenging models of granite formation that rely on magma chambers.
The Global Precipitation Measurement satellite tracked Typhoon Halola's strengthening and intensification, revealing heavy rain rates of over 84 mm/h. The storm's tall thunderstorm towers reached heights of over 10.5 miles, releasing energy that can lead to intensification.
A new algorithm, DeMAND, is helping scientists identify the full repertoire of proteins affected by a drug. By analyzing gene expression changes and protein interactions, DeMAND provides a more comprehensive picture of a drug's effects.
A University of Delaware-led study found that an intensive regimen of regular exercise and a healthy diet can reduce the short-term onset of knee pain for overweight adults with Type 2 diabetes. The study, published in Arthritis Care and Research, shows a 15% decrease in knee pain development among those who underwent the intensive pro...
Researchers at Rice University have developed a new method to incorporate light-capturing nanomaterials into solar panels, increasing efficiency and reducing costs. This breakthrough could help meet the US goal of reducing solar electricity costs to 6 cents per kilowatt-hour.
New research reveals that gender faultlines can appear when individuals share demographic traits and professional interests, leading to a stronger sense of in-group identity among employees. The study found that such faultlines have a negative effect on employee loyalty, but a supportive diversity climate can mitigate this issue.
A team of researchers at Washington State University has discovered a novel structural function of the protein ATF5, which guides transcription and provides structure within the centrosome. This finding sheds light on the role of ATF5 in cell division and its potential implications for cancer growth and disease treatment.
Researchers at Washington State University found no accumulated glyphosate in human milk despite widespread use of Roundup herbicide. The study's results contradict a previous, unverified claim and provide strong evidence for the safety of breast milk.
A new Rutgers University study found that a hormone deficiency in the brain can lead to overeating and a preference for high-fat food. Researchers discovered that reducing glucagon-like peptide-1 (GLP-1) in the central nervous system caused mice to consume more calories and show an increased preference for high-fat foods.
A team of researchers has discovered that abrupt warming events played a key role in the mass extinction of megafauna during the last ice age. The study found that rapid warming, not sudden cold snaps, was the cause of extinctions among species such as mammoths and giant sloths.
University of Pennsylvania engineers have discovered a silicon-based photonic device sensitive to photon spin, enabling faster and more efficient computing. This breakthrough could lead to the development of photonic computers that exploit the spin of photons, potentially orders of magnitude faster than current technology.
A new online portal provides a robust online interactive database to address the 'antibody crisis' in molecular biology. The Histone Antibody Specificity Database allows scientists to find reliable antibodies for their research with higher confidence, using validated test results.
The new guideline provides a comprehensive framework for clinicians to manage gastrointestinal symptoms in children with autism spectrum disorders. It highlights the importance of nutrition management in addressing feeding and GI concerns, and recommends a standard manual of care for clinicians worldwide.
A new study from King's College London found that many of the same genes affect GCSE results in a range of subjects, including English, mathematics, science, and humanities. The research suggests that genetic factors explain over half of the differences between children's educational achievement across all disciplines.
Researchers found that men with low-risk prostate cancer are increasingly opting for active surveillance, while those with higher-risk tumors are receiving more aggressive treatments. This shift aims to reduce overtreatment and improve outcomes for patients.
Researchers developed an algorithm dubbed ENVE to detect genetic aberrations in tumors using deep sequencing data. The algorithm resolves most noise issues and reveals areas where genetic changes have gone awry, potentially leading to more effective treatments for multiple types of cancer.
A new study examined brain networks in veterans with trauma exposure using functional magnetic resonance imaging and graph theory tools. The researchers found that veterans with more severe PTSD re-experiencing symptoms showed weaker connectivity in two brain networks, including the hippocampus and prefrontal cortex.
Researchers are investigating the effects of endocrine disrupting chemicals on child behavior, memory, and learning. The four-year study aims to close a gap in research by examining thyroid hormone levels and their association with chemical exposure during pregnancy, infancy, or childhood.
Researchers identified the hectic emergency department environment and lack of baseline cognitive state as major barriers to delirium recognition. Doctors emphasized the need for a rapid screening test and a 'physician-proof' dementia screening tool to improve detection rates.
Research from The University of Manchester found that English people who upgrade their social status experience greater autonomy and control, leading to increased happiness. In contrast, Americans who rise in society's ranks are less satisfied than those who remain at lower levels.
Astronomers discovered jets of material ejected by still-forming young brown dwarfs, confirming they form through a scaled-down version of star formation. The presence of these jets was detected by the VLA and confirmed with Spitzer and Herschel space telescopes.
A study by University of Florida researchers found that body fat can send signals to the brain, affecting how it deals with stress and metabolism. The discovery reveals a novel fat-to-brain feedback network that was previously thought to be mainly driven by the brain.
A new study from Harvard T.H. Chan School of Public Health finds that over 70% of pollen and honey samples collected from foraging bees in Massachusetts contain neonicotinoids, a class of pesticide linked to Colony Collapse Disorder. The study suggests that these pesticides pose significant risks to bee health and human exposure.
A study by Dartmouth physicist Robyn Millan and NASA's Van Allen Probes has discovered new X-ray actions caused by solar flares, affecting Earth's atmosphere. The findings provide insight into the processes that can impact our lives directly.
Researchers at University of Birmingham discovered how mutated FLT3 genes reprogram blood stem cells, leading to abnormal cell production. The findings provide hope for developing new treatments for acute myeloid leukaemia.
A study published in Clinical Infectious Diseases found that 47% of grocery store-bought meat products contained Klebsiella bacteria, with many strains resistant to antibiotics. This increase poses a significant risk to human health, particularly for urinary and blood infections.
A new special issue in ecancermedicalscience explores the complex relationship between diet, metabolism, and cancer. Researchers investigate the role of antioxidants, obesity, and biomarkers in cancer development and prevention.
The discovery of Tetrapodophis amplectus, a four-legged snake fossil from Brazil's Crato Formation, supports the idea that snakes evolved from burrowing ancestors. The species' unique features, including short snout and flexible jaw, suggest it was adapted for grasping prey or clasp during mating.
Researchers found that genetically distinct cells in pregnant mothers, known as microchimeric cells, promote reproductive health and prevent pregnancy complications like prematurity and stillbirth. These cells help the immune system recognize and accept non-inherited maternal antigens, suppressing an immune system attack on the fetus.
Researchers have discovered a way to control magnetism using organic molecules, potentially leading to more efficient and cost-effective storage technologies. The study found that three molecular layers of phtalocynine can stabilize the magnetic orientation of cobalt surfaces, even in the presence of external magnetic fields or cooling.
Researchers found that stressed juvenile finches learn foraging skills exclusively from unrelated adult birds, ignoring their parents. This change may help avoid negative feedback loops and potentially more adaptive behaviors.
Researchers at Beth Israel Deaconess Medical Center found that endovascular aortic repair provides better outcomes, including lower mortality rates and shorter hospital stays, compared to open surgical repair. The study shows improved long-term results over time, with benefits extending up to eight years after surgery.
A 30-year longitudinal study shows that frequent social interactions at age 20 and quality relationships at age 30 are beneficial for well-being later in life. Meaningful social engagement starts having its greatest impact at age 30, but is also beneficial at any age.
Proteins in the Wnt signaling pathway play a critical role in driving kidney scarring, which can lead to chronic kidney disease. Boosting expression of Wnt proteins in healthy kidneys may be an effective strategy for treating chronic kidney disease.
A multi-institutional research team discovered that early animals took their first breaths with only a slight increase in oxygen levels, contradicting the long-held theory of dramatic oxygen changes. This finding provides new insights into the evolution of complex life forms like whales and sharks.
A University of Michigan study found that teens using marijuana for medical reasons are 10 times more likely to say they're addicted than those who use it illegally. The study highlights the need for improved medical marijuana policies to address teen addiction.
A UTHealth researcher has been awarded a grant to analyze the genetic and social network aspects of HIV transmission clusters. The study, led by Dr. Kayo Fujimoto, will compare social clustering by venue to common viral strains of HIV infection.
Researchers at Ben-Gurion University have developed a new one-step graphene production process that is faster and potentially scalable. The lamp-ablation method produces high-yield few-layer graphene without toxic substances.
A study published in PLOS Pathogens found that older individuals are more susceptible to West Nile virus due to impaired immune responses. The researchers discovered that older mice had delayed antibody responses, reduced helper T cells, and lower chemokine levels, leading to higher viral loads and increased brain damage.
A team of engineers and doctors at Vanderbilt University has developed a surgical robot with steerable needles equipped with wrists that provide needlescopic tools with previously lacked dexterity. This innovation allows for precise resections, suturing, and access to areas such as the nose, throat, ears, and brain.
Researchers at Cardiff University have identified a critical function of the DISC-1 gene that plays a crucial role in brain development and plasticity. The study reveals a vulnerable period in early brain development where failure to bind with specific molecules leads to irreversible effects on later-life plasticity.
Leading cancer experts recommend several measures to reduce high cancer drug prices, including a post-approval price review mechanism and Medicare negotiations. The recommendations aim to improve patient care and alleviate the financial burden on those affected by high cancer drug costs.