Researchers found that the immune system's attack on new blood vessel cells in fetuses may be responsible for life-threatening brain bleeds. This discovery challenges the previous belief that low platelet counts were the cause of fetal brain bleeds, suggesting a need for alternative therapies.
A new study by University of Utah researchers reveals the existence of an unknown layer inside Earth's lower mantle, where rock gets three times stiffer. This stiffness increase may explain why slabs of sinking tectonic plates stall and thicken at a depth of 930 miles underground.
A Carnegie Mellon University study found that when smartphone users learn the frequency of app location sharing, they quickly limit further sharing. Participants who received daily 'privacy nudges' detailing their app's access to sensitive information restricted permissions more than those who used an app permission manager.
A team of Singapore-based scientists identified a new signalling pathway regulating cancer internal diet. The therapy combines an old anti-malarial drug with CK1α inhibition, effectively treating colon and bladder cancers. Researchers hope to develop more potent inhibitors for this treatment.
New research reveals that non-native plants are less widespread and do not outcompete native species, suggesting alternative causes for vegetation change. High diversities of native and non-native plant species coexist in locations with high native species diversity.
Glioblastoma's aggressive nature is fueled by mTOR-induced pathways, but mTOR inhibitors have shown limited effectiveness. Compensatory glutamine metabolism plays a crucial role in mTOR inhibitor resistance, as evidenced by increased glutaminase and glutamine levels in GBM cells and tumor xenografts.
A new study evaluates currently available screening tools for senior cancer patients taking too many medications. It found that a more comprehensive assessment and monitoring plan is needed to improve treatment outcomes.
A team of chemists from the University of Wisconsin-Madison has developed a method to precisely order molecules in organic glasses, leading to more efficient and durable portable electronic devices and potentially new generations of solar cells. This breakthrough could result in displays that produce more light using less energy.
A new study suggests discontinuing statins in patients with life-limiting illness can improve quality of life without adverse health effects. The study found no significant differences in mortality between those who continued and discontinued statin therapy.
A report by University of Montreal researcher Yves Carrière finds that delaying retirement eligibility will widen disparities among older adults. This policy change is expected to disproportionately affect those with lower incomes, who will be more reliant on private savings for support.
A genome-wide screen of zebrafish identified an enzyme, pregnancy-associated plasma protein-aa (pappaa), that promotes learning and memory by increasing IGF availability to neurons. The study's findings have implications for understanding human neuropsychiatric disorders, such as schizophrenia, autism, and obsessive-compulsive disorder.
A two-year clinical trial using low doses of ketamine may hold promise for reversing the devastating symptoms of Rett Syndrome, a neurodevelopmental disorder found almost exclusively in females. The trial aims to measure changes in breathing patterns and overall clinical severity among up to 35 participants.
Researchers found that soils with rich organic material and low phosphate absorption show low radiocesium interception potential. Soils with high clay or silt content adsorb radiocesium more readily due to higher mica content.
A new study from Brigham and Women's Hospital found that Asian-Americans diagnosed with cancer have significantly lower cancer-specific mortality rates compared to non-Hispanic white patients. The study analyzed data from over 2.5 million patients and broke down the population into eight subgroups, revealing variations in survival rate...
A Clemson University study found that universities with locally available supercomputers were more efficient in producing research in critical fields such as chemistry and civil engineering. The study used data from the National Research Council survey of 212 institutions, including 177 universities with high or very high research levels.
Researchers found that most people with HIV exercise at home, but not intensely enough. The study suggests designing a flexible plan to maximize health benefits of exercising.
Scientists developed a new way to cook rice that increases resistant starch content, potentially reducing calories absorbed by the body by over half. This simple cooking method can transform digestible starch into indigestible resistant starch, lowering usable calories and addressing obesity rates.
A Harvard scientist has developed a new microfluidic design that can detect and extract biomolecules from fluid mixtures more efficiently than current techniques. The approach uses microscopic fins embedded in a hydrogel that responds to different stimuli, allowing for the selective separation of target biomolecules.
The Michael J. Fox Foundation is supporting research on a novel therapy for Parkinson's disease by Dr Bryce Vissel and Sandy Stayte at the Garvan Institute of Medical Research. The prototype drug targets kainate receptors to slow disease progression.
Researchers at Princeton University discovered that cytomegalovirus manipulates fatty acid elongation, a process essential for virus replication. The virus induces the expression of elongase enzyme 7, which is necessary for efficient replication.
Scientists report preliminary studies suggesting chlorine treatment in wastewater plants may create new, stronger antibiotics. This could contribute to growing antibiotic resistance problem and harm aquatic life.
Researchers found that vitamin D supplements slowed tumor growth and reduced inflammation in men with low-grade prostate cancer. The study suggests that vitamin D may improve treatment outcomes for these patients by reducing the need for aggressive treatments.
A study by Queensland University of Technology found that almost half of respondents modified medication dosage forms without seeking advice from healthcare professionals. The research highlights the potential dangers of crushing tablets or modifying capsules, which can lead to reduced effectiveness and increased risk of adverse effects.
Researchers have programmed bacteria to generate a hunger-suppressing lipid, leading to reduced body fat and staved-off diabetes in mice. The therapeutic bacteria could provide sustained drug delivery, potentially improving weight loss outcomes for humans.
A promising new antivenom derived from opossum serum has shown promise in neutralizing snake venom, with potential for widespread distribution and a single injectable dose. The peptide-based treatment could save thousands of lives worldwide without the side effects of current treatments.
Researchers at Purdue University have developed a method to convert waste packing peanuts into high-performance carbon electrodes for rechargeable lithium-ion batteries. The new anodes outperform conventional graphite electrodes and charge faster, making them a promising environmentally friendly solution.
Researchers find that nitrogen dioxide and ground-level ozone can increase the potency of airborne allergens, contributing to rising allergy rates. The study suggests chemical modifications of allergenic proteins may play a key role in the increasing prevalence of allergies worldwide.
Research links genetic changes in bowel tumours to immune system responses, suggesting potential for targeted immunotherapy treatments. Genetic profiles could be used to diagnose suitability for immunotherapies and tailor treatment plans.
A study by Brigham and Women's Hospital found that routine potassium monitoring for healthy women taking spironolactone for acne does not change the course of treatment, but cumulatively costs $80,000. The researchers suggest ending routine testing to improve patient care experience and reduce healthcare spending.
A molecule from plants and trees, lignin, could be used to create asphalt and sealant mixtures that are more environmentally friendly and durable. Lignin, a renewable resource found in trees, has been integrated into bitumen to improve its performance and reduce the amount of non-renewable oil needed.
Climate change is expected to accelerate the emergence of vector-borne diseases such as chikungunya and dengue fever in the UK. Rising temperatures could enable disease-carrying mosquitoes like Aedes albopictus to survive across large parts of England and Wales within decades.
Scientists convert packing peanuts into high-tech carbon microsheets and nanoparticles for use in rechargeable batteries, achieving higher energy storage capacity than existing materials. The new process uses lower temperatures and produces more environmentally friendly materials.
Scientists at Kansas State University have developed a haplotype map of wheat that provides a detailed description of genetic differences in worldwide wheat lines. This study enables the precise mapping of genes and increases the selection of best lines for breeding, leading to faster release times for new varieties.
A large national survey found that nursing home directors with greater palliative care knowledge experienced less aggressive end-of-life care, including reduced use of feeding tubes and emergency room visits. This association suggests that improving staff knowledge could lead to better care for thousands of residents.
A recent Carnegie Institution study has identified three SWEET family proteins essential for delivering sugars from plant leaves to embryonic plants inside seeds. The research found that eliminating these transporters retards embryonic development and reduces seed quality, with potential applications in crop yield enhancement.
Research reveals that changes to environment, such as building walking paths and playgrounds, improve nutritional quality of foods and increase physical activity levels. However, more research is needed to draw conclusions on the effectiveness of policy and built environment changes.
The National Nanotechnology Initiative (NNI) has published a report assessing the status of environmental, health, and safety (EHS) risk science in nanotechnology. Stakeholders identified four key areas for improvement: communication resources, decision tools, data resources, and standards and guidance resources.
A new study suggests that a 40,000-year-old volcanic eruption may not have triggered the final demise of the Neanderthals. Climate modeling indicates that temperatures decreased by 2-4 degrees Celsius in Western Europe after the eruption, which could have impacted day-to-day life for both Neanderthals and early humans.
Researchers at Saarland University found that even brief power naps (45-60 minutes) can significantly improve retention of learned material in memory. Memory performance remained constant after sleeping, but participants recalled information better than those who didn't nap.
A recent study found that pigs fed diets containing corn-ethanol co-products, such as distillers dried grains with solubles (DDGS), had no significant differences in growth performance compared to those fed a traditional corn-soybean meal diet. The study showed that conventional, high-protein, or uncooked DDGS can be safely included at...
Researchers at Penn Medicine have discovered hypermethylation of the C9orf72 gene may protect against certain neurodegenerative diseases. Patients with hypermethylation showed more dense grey matter in affected brain regions, suggesting a potential neuroprotective target for drug discovery.
A new study from Michigan State University finds that several additives claiming to break down plastics do not work in common disposal situations. The team tested five additives and three categories of biodegradation methods but found no difference between plastics with additives and those without.
Antibiotics are widely used in lab experiments for microbiology, molecular biology, and genetic research. However, this practice contributes to the growing problem of antibiotic resistance, posing a catastrophic threat to modern medicine. Researchers must use antibiotics more responsibly and sparingly.
A Danish-led project, EGRIP, will drill a 2½-kilometer deep ice core through northeast Greenland's large ice stream to gain new knowledge about the speed of ice movement and its contribution to rapid loss of the Greenland ice sheet. This information could improve forecasts of future sea level rise.
A recent study published in Language journal provides new evidence for the Indo-European steppe hypothesis, suggesting that languages diverged approximately 6,500 years ago. This finding is supported by a phylogenetic analysis of over 200 sets of words from living and historical Indo-European languages.
The HAWC Gamma-Ray Observatory is equipped with 300 detectors spread over three football fields to detect gamma rays and cosmic rays. It will study active galactic nuclei, gamma ray bursts, and the nature of cosmic rays.
The new self-learning welding system is controlled by a neural network program that tracks multiple variables, such as bevel angle, thermal profile, and weld form to detect and correct errors in real-time. This technology has the potential to bring significant savings to the welding industry by eliminating post-welding checks and repairs.
A new study by UCLA professor Jingyi Jessica Li and Mark Biggin from Lawrence Berkeley National Laboratory concludes that transcription plays the largest role in determining protein abundance. The research highlights the importance of accurate measurement and analysis methods for modeling gene expression.
Researchers discover that combining Sodium Formate with metal-based cancer treatment JS07 can greatly increase its effectiveness against ovarian cancer cells. The potent form of JS07 disrupts cancer cell's energy generation mechanism, leading to cell shutdown and potential reduction in side effects.
A study by St. Jude Children's Research Hospital found that measuring residual leukemia cells in patient bone marrow during early weeks of chemotherapy helps identify high-risk patients who need intensive therapy. The technique improved survival rates for young leukemia patients, with 93.5% alive five years after diagnosis.
A research team at Montana State University and Sweden has discovered an antioxidant system in liver cells that helps sustain function during a crisis. The system is powered by methionine, an amino acid found in high levels in egg, meat, fish, Brazil nuts, sesame seeds, and cereal grains.
African cattle infected with the deadly East Coast fever parasite are less likely to die when co-infected with its milder cousin. The findings suggest a protective process that could also be at work in human malaria, where infections with milder parasites may protect against severe disease.
Researchers have discovered that a specific set of molecules, known as transcription factors, trigger DNA errors and slow down cell division in embryos. This finding provides new insight into the mechanism behind the 'midblastula transition', where the embryo takes control of its genetic expression.
Tropical Cyclone Nathan made landfall on March 19 at the Cape York Peninsula in northern Queensland, with sustained winds reaching over 30 meters per second. NASA's RapidScat instrument revealed the strongest winds were south of the center before landfall, and the storm was moving west across the peninsula.
A computer modeling analysis led by UC Irvine scientists found that levee detonations in 2011 reduced the risk of flooding in a city upstream. The study showed that allowing levees to overtop naturally would have resulted in less erosion and similar damage to crops and buildings.
Researchers at the University of Warwick have identified a biomarker linked to both rheumatoid and osteoarthritis, potentially leading to an early diagnosis of OA and RA. The development of a blood test using this biomarker could help patients receive treatment several years before physical symptoms appear.
Researchers have successfully controlled quantum states in a silicon wafer, achieving a record-breaking quantum on/off switching time of about 1 millionth of a millionth of a second. This breakthrough could lead to the creation of fast quantum silicon chips and ultra-sensitive bio-medical sensors.
A Monash University study reviewed over a million ICU patients in Australia and New Zealand, finding one in eight did not meet current sepsis criteria. The classic definition of sepsis may be missing critically ill patients, particularly the elderly or those on medications that affect heart rate or immune systems.
Nexus theory reconciles GR and Quantum Theory, explaining dark matter as the nexus graviton's constant rotational motion. The theory also sheds light on perplexing questions in physics, including a quantum description of Black Holes without singularities.
Scientists at the University of Rochester have developed a method for encoding 2.05 bits per photon using twisted light, doubling existing systems that use light polarization. This breakthrough could help increase the efficiency of quantum cryptography systems and secure communication.