The Canadian population aged 85 and over has grown to 702,000 by 2013, representing 2% of the total population. As the 'oldest old' category continues to evolve, it will impact public policy and require distinct services.
The common squid has 60% of its RNA transcripts edited, creating vast protein diversity and potential role in brain physiology
A study by Wake Forest Baptist Medical Center found that 27% of acne patients failed to get prescribed medications, with higher non-adherence rates for those taking multiple medications. Researchers suggest simplifying treatment regimens could reduce non-adherence.
A new paper by Zhi Da at the University of Notre Dame finds that residential electricity usage can track household production in real time, helping to price assets. The research shows that consumer product related industries are risky as they have high exposure to household production risk.
The Canadian Space Agency has delivered its hardware contribution to the ASTRO-H mission, a flagship x-ray astronomy observatory. Professor Brian McNamara will study the effects of black holes on emergent galaxies, utilizing one of the most sensitive spectrometers in orbit.
A team of scientists has discovered five new forms of silica under extreme pressures at room temperature, revealing a four-to-six configuration shift in the deep Earth. The findings provide valuable insights into the transition between different chemical phases under high-pressure conditions.
A new international study finds that glacier movement in the Southern Hemisphere is primarily influenced by sea surface temperature and atmospheric carbon dioxide rather than changes in the Earth's orbit. The results contradict the Milankovitch theory of climate, which suggests orbital fluctuations drive ice sheet expansion in the Nort...
Researchers found that patients with narrower PICC lines and those taking aspirin and statins before PICC placement have a lower risk of DVT. Doctors should use PICCs only when necessary and monitor for clots, ensuring continued medication to prevent complications.
A 10-year study on tiger DNA has provided new insights into the genetics of tigers, allowing for more effective conservation strategies. The research found that extinct subspecies are nearly identical to surviving ones, providing powerful tools for forensic identification and management.
Researchers found that MED15 overexpression is associated with higher mortality rates in HNSCC patients with cancer recurrence, particularly in oral cavity/oropharyngeal tumors. MED15 may serve as a prognostic marker for HNSCC recurrence and as a therapeutic target in HNSCC patients suffering from recurrences.
A study found that investigators are more likely to respond to clinical trials if contacted by a point person or navigator. The Point-Person Project built a national network of navigators to find experts in pediatric clinical research.
A new method called Brain-Wide Association Analysis (BWAS) has isolated the functional differences between autistic and non-autistic brains, identifying regions that may contribute to autism symptoms. The study used a large dataset of MRI scans to compare brain connectivity in individuals with autism and those without.
A new study found that large protected areas in the Xingu River Basin have limited the negative impacts of expanding agriculture on the region's water cycle. The research combined fieldwork, satellite data, and dynamic vegetation models to simulate the water budget, finding that deforestation has had a small effect on the area.
Most firms in the digital camera sector adopt straightforward competitive pricing for 60% of new products. The choice of strategy depends on market, firm, and brand characteristics. Firms use various dynamic pricing strategies simultaneously over a portfolio of products.
Researchers at ICFO have successfully generated isolated attosecond pulses at the carbon K-edge, enabling real-time imaging of electronic motion in organic compounds and ultrafast devices. This breakthrough has significant implications for designing new materials and developing petahertz electronics.
As the US population ages, chronic subdural hemorrhage (SDH) is expected to become the most common adult brain condition requiring neurosurgical intervention. By 2030, hospitals and neurosurgeons may be under-manned to handle the projected increase in patients with SDH.
A study reveals that 70% of the world's remaining forests are within a half-mile of their edges, facing harm from urbanization and agricultural influences. Habitat fragmentation reduces plant and animal diversity by 13-75%, with negative effects magnifying over time.
Researchers have developed a new fluorescence microscopy technique that shows where and when proteins are produced in individual cells. The technique allows direct observation of messenger RNA molecules being translated into proteins, shedding light on protein synthesis irregularities contributing to human diseases.
Researchers have identified a compound that blocks HIV entry by targeting both CCR5 and CXCR4, reducing the risk of resistance and making treatment more effective. This finding has significant implications for the development of new HIV treatments and could potentially keep treatment affordable for millions in the developing world.
A large study found twice as many diagnosed autisms among ART births compared to non-ART births, but most of the association was explained by maternal age and education. After accounting for these factors, an elevated risk was only seen in mothers aged 20-34, with no significant increase in singletons.
Research suggests that immigrant health policies should be tailored to individual groups, taking into account age and health indicators. A comprehensive review of 75 studies found that new immigrants have a healthier profile than the general population, but this advantage diminishes over time.
A study led by Benoît Laplante finds that consensual unions have become increasingly popular among higher-income groups in Latin America. University-educated women are no longer limited to having children out of wedlock, as fertility rates correlate with living in a conjugal relationship rather than its legal nature.
Researchers at Rockefeller University identified Sox9 as a key molecule controlling stem cell plasticity in hair follicles. Sox9 enables hair follicle stem cells to regain their ability to produce new tissue and heal wounds by amplifying genes associated with stemness.
Researchers at the University of Adelaide have discovered that resistant barley varieties accumulate beta-glucan in their cell walls, which may influence nutrient flow and natural defense strategies against cereal cyst nematode. This finding could lead to new targets for resistance strategies in barley and other cereal crops.
Researchers from University of Cologne measured vibrational transitions in CH5+ ions with high accuracy, revealing the molecule's structure. The findings confirm a simple model of five hydrogen nuclei moving freely around the carbon nucleus.
Researchers develop robotic materials that can sense their environment and change their properties in response. Inspired by nature, these materials aim to create prosthetics, self-healing bridges, and adaptive vehicles. However, manufacturing techniques remain a challenge, and an education gap must be addressed.
Researchers from MDC have discovered a novel molecular signaling pathway in the kidney that regulates epithelial barrier function and lumen expansion. The Grhl2 transcription factor teams up with Ovol2 to control genes essential for forming an impermeable barrier.
Research reveals vitamin D's role in preventing chronic inflammation that causes cardiometabolic disease, including type 2 diabetes and heart disease. Vitamin D helps immune cells reduce inflammation and prevent the formation of fat-laden macrophages.
A stem cell-based approach using human embryonic stem cells proved effective in improving insulin sensitivity and glucose metabolism in mice. The combination of stem cell transplantation and antidiabetic drugs resulted in rapid weight loss and significant improvements in glucose control compared to individual treatments.
A recent study reveals that glacial melt in a small region of Alaska produces more than four times the total freshwater discharge of the Yukon River and half again as much as the Mississippi River. The findings provide new insights into marine biology, ocean currents, and sea level changes.
Researchers developed a scale to quantify student engagement, which is positively correlated with academic performance and motivation. The scale can help educators identify barriers and increase student involvement in the classroom.
A research team at UCSF has discovered a noncoding RNA molecule called Pnky that can be manipulated to increase the production of neurons from neural stem cells. The study suggests that Pnky may have broad applications in regenerative medicine, including treatments for Alzheimer's disease and Parkinson's disease.
HIV+ kidney transplant recipients who are not infected with HCV have similar 5-year and 10-year kidney survival rates as uninfected recipients. Patient survival among mono-infected HIV+ recipients is also comparable to uninfected recipients, while co-infected patients experience inferior outcomes.
Scientists have identified PDE-9 as the long-sought culprit in heart failure by analyzing lab animals and human heart cells. The enzyme interferes with the body's natural 'braking' system, leading to progressive weakening and stiffening of the heart muscle.
Scientists at the University of Manchester have created an enhanced surface for silicone breast implants that mimics the body's own skin cells. This new surface reduces foreign body reactions and may help lower the risk of capsular contracture, a common complication after breast implant surgery. The study suggests that this biomimetic ...
Researchers aim to target autophagy pathway, a key enzyme involved in cancer and neurodegenerative diseases. They plan to use high-throughput screening facilities to identify new inhibitors of Ulk1, a critical on-off switch regulating the pathway.
Researchers in Berlin have successfully generated human T cell receptors that specifically recognize and destroy cancer cells. The breakthrough, published in Nature Biotechnology, could lead to new cancer therapies by training the immune system to attack tumor cells.
Researchers made direct observations of cosmic dust resulting from an ancient supernova at the Milky Way's center, supporting the theory that supernovae produce dust in galaxies of the early universe. The study provides new insights into the origins of dust, a crucial component in star and planet formation.
A study published in Current Biology reveals that the dusky dottyback, a small predatory fish found on coral reefs, changes its color to mimic other fish species to hunt juvenile offspring. This clever strategy also helps the fish avoid detection by predators.
A Cancer Research UK study found that text message reminders increased breast cancer screening attendance by 20% among women aged 47-53. The trial, which sent text messages to over 450 women, showed that 72% of those who received the reminders attended their appointments compared to 60% of those who did not.
The study found a 12% reduction in blood transfusions and increased discharge to home by 9.3%, reducing hospital stays and healthcare costs. Topical tranexamic acid administration enables precise control over drug concentration, potentially reducing infection rates.
Cyclone Nathan strengthened to hurricane force as it approached landfall in Queensland's Cape York Peninsula, with sustained winds increasing to over 30 meters per second. The storm was moving west at 6 knots and generating rough seas, threatening coastal erosion upon landfall.
A study by New York University and the University of Pennsylvania found that humans have difficulty ignoring visual dimensions even when it harms performance. This ability to combine multiple components of an item while underscoring the challenge faced by medical practitioners and airport screeners is a result of our automatic multi-ta...
Two new plant species, Psoralea diturnerae and P. vanberkelae, have been discovered by citizen scientists in the Cape Floral Kingdom of South Africa. The discovery was made possible through the efforts of a group of amateur botanists known as the Outramps, who have been conducting regular expeditions to monitor and conserve rare species.
Researchers developed a new brain image analysis method to track beta-amyloid plaque deposition in Alzheimer's disease, using positron emission topography (PET). The new approach, which uses cerebral white matter as a reference region, improves the tracking of amyloid changes and evaluates investigational treatments.
Researchers at Michigan State University reveal two hidden benefits of electric vehicles: reduced heat emission and potential cooling effect on city dwellers. The study finds that replacing gas-powered vehicles with electric ones could reduce urban heat intensity by nearly 1 degree Celsius, saving energy and carbon emissions.
Researchers at CIFAR discover that charge ordering creates a stripy pattern, not a checkerboard, and competes with superconductivity along one direction. This discovery sheds light on the role of charge ordering in propelling electrons into tight pairs, allowing for free movement.
Researchers at the University of Illinois have developed an adaptive control technology that can override failures and maintain safe handling in aircraft. The L1 system has been tested on a manned aircraft and shown consistent performance across varying flight conditions, making it a promising solution for improving air travel safety.
Researchers at the University of Otago have identified key genetic mutations underlying deadly hereditary stomach and lobular breast cancers. The team found that these mutations also create vulnerabilities in cancer cells, making them susceptible to existing drug therapies targeting other cellular mechanisms.
Researchers discovered that minor clones present at low levels in leukemia cells often drive relapse, contradicting the assumption that mutated cells with more mutations are more likely to survive therapy. The study's findings have implications for monitoring patients in remission and detecting signs of relapse.
Researchers are developing microfluidic solutions for easy-to-use, disposable, inexpensive, and high-throughput sperm selection. These methods offer promising results for single-sperm genomics, in-home male fertility testing, and wildlife conservation efforts.
A new millipede species has been found in Launceston's city parks and reserves, with a known range of less than 12 square kilometers. The species, Tasmaniosoma anubis, does not appear to be threatened despite its small range.
Researchers have discovered a way to boost the effectiveness of immunotherapy in treating glioblastoma by enhancing dendritic cell migration. This approach increased patient survival rates by over 36 months compared to traditional dendritic cell-based therapy alone.
A new genetic method called MCR enables biologists to rapidly generate mutations in both copies of a gene, accelerating genetic research on diverse species. This method has the potential to control insect-borne diseases such as malaria and animal/plant pests by disseminating genetic elements with high efficiency.
Researchers discovered that bioluminescent fungi produce light to attract insects that disperse their spores. The circadian control of bioluminescence makes the process more efficient and helps the mushrooms save energy. Studying these organisms is crucial for understanding forest ecosystems and the carbon cycle.
A new project at the University of Illinois is using tablet computers to provide perinatal depression screenings to low-income mothers. The mHealth technology allows women to complete the screening in their preferred language and provides a paperless alternative to traditional screenings.
Rutgers University chemists have developed a patent-pending HER catalyst Ni5P4 that has the potential to replace platinum in electrolyzers and fuel cells, lowering material costs while maintaining efficiency. The researchers aim to test the compound's operating stability and efficiency over extended time periods in commercial devices.
Research found that music TV exposure triggers increased sexual activities in boys but not girls, due to perceived peer norms. Girls exhibit resistance to media content portraying women as objects of lust, leading them to watch less music TV.
A study by Ohio State University researcher Hui Zheng found that medical expansion in 28 countries led to people feeling less healthy over time. Despite increased access to medicine and medical care, self-rated health decreased, with percentages dropping from 39% to 28% in the US between 1982 and 2006.
Institutions like King's College London are reviewing military medical advancements to improve civilian healthcare, focusing on low-resource regions where life-saving treatments can be adapted and implemented. The review calls for research and policy changes to transfer these innovations.