Researchers have identified a potential new way to predict which patients with head and neck cancer may benefit most from chemotherapy. The use of dynamic contrast-enhanced MRI scans has shown that tumour blood flow can predict response to treatment, with patients having high blood flow more likely to respond.
Tropical Depression 9 is battling strong vertical wind shear and dry air, leading to its weakening. The depression is expected to degenerate into a remnant low pressure area in 24 hours or less due to persistent environmental conditions.
A recent study by Dr. Sylvie Belleville and her team has identified typical patterns of brain progression towards Alzheimer's disease, revealing a complex path characterized by periods of stability followed by accelerated decline. The study suggests that rapid memory decline is a key indicator of risk, allowing for earlier treatment.
People fed β-glucan-enriched pasta for two months showed increased populations of beneficial Lactobacilli and reduced LDL cholesterol. The study also found an increase in certain short-chain fatty acids with anti-inflammatory activity.
UAB researchers discovered a triple mechanism that stops chromosome separation in response to DNA injuries, preventing cancerous transformation. The three control pathways, mediated by genes Wee1, Pds1/securina and Rad53/Chk2, must be eliminated simultaneously for damaged chromosomes to be segregated.
Scientists have found that local structures in liquid water persist for longer than a picosecond, contradicting the general perception of water as a solvent. This discovery was made using ultrafast vibrational spectroscopies and has significant implications for understanding chemical and biological reactions on Earth.
A new study suggests that in-hospital nocturnal dialysis may be beneficial for patients' hearts as well as their kidneys. The procedure was found to reduce left ventricular mass by a significant margin after one year, which is associated with a lower risk of cardiovascular diseases such as heart failure, heart attack, and stroke.
The 'Tree of Life' for 2.3 million species has been released, depicting relationships among living things over time. The collaborative effort combines smaller trees from various sources, with the goal of creating a comprehensive and editable online resource.
Researchers at Thomas Jefferson University found that patients with metastatic cancer are at high risk of venous thromboembolism after surgery, and a personalized approach to anticoagulation therapy is needed. The study suggests that the primary type of cancer may play a role in determining the risk for blood clots.
Researchers at Michigan State University found that Chinese farmers are adapting to shrinking domestic soybean fields by planting more profitable crops like corn, but this shift has environmental implications. Meanwhile, pockets of resilience in soybean cultivation suggest potential solutions for China's burgeoning food demand.
Researchers found early ultrasound signs of water absorption changes in cervix before delivery, indicating potential preterm birth risk. Current cervical length measurement methods are limited in their usefulness.
Involving parents in the treatment of adolescents with bulimia nervosa is more effective than treating the patient individually. Family-based therapy achieved higher abstinence rates from bingeing and purging compared to cognitive behavioral therapy, according to a randomized clinical trial.
A new study published in PLOS ONE found that higher doses of hydrocortisone are not associated with brain injury or neurodevelopmental impairments in extremely low birthweight infants. However, the study suggests that lower doses of hydrocortisone may improve cognitive outcomes.
The study aims to develop machine learning models that mimic the toddlers' ability to recognize objects, leveraging 500 hours of video and 54 million images from over 100 children. The research could lead to more sophisticated digital object-recognition technology.
The European Commission Joint Research Centre has found that the uncertainty in solar photovoltaic power measurements can be reduced by more than half, allowing for tighter margins and increased accuracy. This breakthrough could lead to cheaper and faster calibration of secondary reference devices, benefiting both industry and research.
Researchers at Caltech found that ocean microbes can consume large amounts of methane using electrons to share energy over long distances. The microbes use a symbiotic relationship to break down methane, which could help mitigate climate change.
A first draft of the 'tree of life' for 2.3 million named species has been released, combining existing branches into a single diagram. The digital resource was created by compiling thousands of smaller chunks and requires software tools to analyze and update.
Researchers are working to design recommendations for scientists and government organizations to work ethically with indigenous peoples. The project aims to improve collaboration between Native American tribes and climate scientists to better plan for climate change.
A study published by the Institute of Food Technologists found that a bean-based meal provided a similar feeling of fullness compared to a beef-based meal. The researchers discovered that plant-based proteins with high fiber content may offer similar appetite regulation as animal protein.
A de-centralized decision-making model shows how positive feedback during exploration proves useful for making good and quick decisions. The model explains how trends take off, such as the popularity of Beats headphones, and the success of word-of-mouth marketing tactics.
New research by University of Houston researchers suggests that patients who improve quickly are more likely to drop out before completing treatment. Patients with high initial anxiety levels were also more likely to discontinue treatment. The study's findings highlight the importance of understanding how patients make decisions about ...
Scientists from India developed a theory governing curved graphene using a quantum simulator based on an optical lattice. The findings could lead to novel graphene-based sensors with controlled deformation.
A study published in Annals of Emergency Medicine found that neighborhood characteristics have a lesser impact on EMS activation for stroke than stroke severity or individual factors. Most patients arrived at the ER within 3 hours, but only about half used EMS, with lower stroke severity and younger age being key determinants.
Researchers developed a custom silicone guide implanted with biochemical cues to promote both motor and sensory nerve regeneration. The study showed improved walking ability in rats within 10-12 weeks, paving the way for human trials.
Scientists at Trinity College Dublin have discovered a fundamental mechanism underlying Alzheimer's disease, which could lead to new forms of therapy. The research, published in Science Advances, highlights the importance of understanding diseases at the molecular level and finding ways to remove toxic amyloid-beta from the brain.
UBC researchers propose a new way to calculate cosmological distances using fast radio bursts, allowing the positioning of distant galaxies in three dimensions and mapping out the cosmos. The method uses the delay between arrival times of different frequencies to create a catalogue of galaxies.
A recent Alberta study found that pharmacist-led care can significantly reduce blood pressure in patients, with patients receiving enhanced care being twice as likely to reach their recommended targets. The RxACTION project demonstrated the effectiveness of pharmacists' independent prescribing and active patient management.
A new study shows that tracking blood pressure data with incentives can lead to lasting changes, with nearly half of participants decreasing their systolic blood pressure. Participants who achieved over 20 milestones showed an average drop in systolic and diastolic pressures, suggesting a potential long-term impact.
A study of Inuit DNA reveals how their unique genetic makeup helps them thrive on a high-fat diet, with genes associated with fat metabolism, height and weight, and cholesterol playing key roles. The research suggests that the Inuit population has undergone significant adaptation to its extreme climate environment.
A new meta-analysis has found that smoking significantly increases the risk of type 2 diabetes, with current smokers at a 37% higher risk than never smokers. The risk decreases after quitting, but former smokers are still at an 18% increased risk after 5 years and 11% more than 10 years ago.
Researchers translate microscopic concepts to study polar sea ice, capturing dynamic forces with a tractable equation. The new approach opens up climate science to nonequilibrium statistical mechanics methods, solving the long-standing challenge of measuring sea ice volume.
A UT Arlington computer scientist is developing novel software engineering methods to detect and mitigate unsafe cyber-physical upgrades in the energy domain. The research aims to create more reliable and safer systems, easing the verification and validation process for software and systems engineers.
Scientists have discovered a new role for basal forebrain neurons in controlling action, enabling rapid stop of planned behaviors. This discovery opens the door to novel approaches for neurological and psychiatric conditions affecting cognitive functions.
Professor Nick Enfield and his colleagues found evidence of a universal trait in human conversation, with the word 'Huh' appearing in 31 languages. They also discovered that people stop for clarification once every 90 seconds, regardless of language.
Researchers at the University of Manchester have discovered a potential new approach to overcome hormone therapy resistance in ER+ breast cancer by targeting breast cancer stem cells driven by NOTCH4. This approach shows promise in improving treatment outcomes for patients with hormone therapy-resistant breast cancer.
Students from Drexel and KAIST will collaborate on nanofabrication and energy storage projects using latest materials and instrumentation. The FIRST Nano2 Co-op Center aims to foster global partnerships in 21st-century technological challenges.
A new study estimates that leptospirosis affects over 1 million people each year, resulting in nearly 60,000 deaths, primarily in resource-poor settings. The disease is spread through contact with contaminated environments and has the potential to grow further due to climate change and urbanization.
PharmaMar has initiated a multicenter, international phase II Basket trial to evaluate the efficacy and safety of PM1183 (lurbinectedin) in patients with various advanced solid tumors. The trial will assess the overall response rate, duration of response, and pharmacokinetic properties of the drug.
Harmful algal blooms and hypoxia pose significant threats to coastal ecosystems, economies, and human health. NOAA's new grants will help communities detect, predict, and manage toxic algae and low oxygen levels using advanced monitoring technologies and robotic systems.
The conference will showcase advancements in acute cardiovascular care, including heart attack, cardiac arrest, and pulmonary embolism treatment. Experts will discuss novel therapies and debate controversial topics such as pre-hospital care and bleeding management.
Researchers at Karolinska Institutet have discovered a mechanism that explains how insulin-producing cells can be both insulin-resistant and insulin-sensitive at the same time. The study identifies a key factor, PI3K-C2α, that causes a switch in signaling pathways, leading to beta cell proliferation.
A team of physicists has discovered stable ferroelectricity in a few nanometers thick strontium titanate film, contradicting expected behavior. This finding could lead to new materials for nanotechnology devices.
Researchers discovered that sponges construct their skeletons through a complex process involving dynamic transport and cementation of spicules. The findings reveal a fundamentally new mechanism of forming animal body shape and may inspire interdisciplinary studies in fields like bioengineering and architecture.
Researchers found that obesity-related immune cell changes appear early, particularly in African-American girls. The study suggests that blood tests could be used to identify teens at high risk of developing cardiovascular disease in the future.
Researchers have successfully trapped single atoms or molecules using a laser light in a doughnut-shaped metal cage. This breakthrough could lead to the development of advanced storage devices, computers, and high-resolution instruments. The technique uses scanning probe microscopy techniques to access individual nano-traps.
Researchers uncover the crucial function of a protein called BuGZ in assembling the spindle matrix and microtubules during mitosis. The discovery could lead to new insights into cancer and other diseases caused by errors in cell division.
A new study published in Diabetologia shows that high protein diets from both animal and plant sources improve blood sugar control and reduce liver fat in patients with type 2 diabetes. Insulin sensitivity improved only in the animal protein group, while the plant protein group showed significant reductions in kidney function parameters.
A study by Stanford scientists has found that the supposed 'global warming hiatus' never occurred, due to flawed statistical methods. The researchers developed a new statistical framework to re-examine temperature data, taking into account temporal and spatial dependencies.
Researchers at the University of Delaware have discovered oviductosomes, tiny particles that help sperm prepare for fertilization. These particles are attached to the sperm like decorations and transfer critical molecules, including a calcium clearance pump, that aid in the fertilization process.
Researchers at Lawrence Livermore National Laboratory have discovered a way to create linear chains of carbon atoms, called carbyne, through laser-melting graphite. This material has potential applications in nanoelectronic devices and superhard materials, as well as tunable semiconductors and hydrogen storage.
Research at Derby Teaching Hospitals NHS Foundation Trust found a 90% medical bed occupancy target reduced hospital death rates by 4.5-4.8% and improved the national 4-hour A&E waiting target performance from 33% to 51.4%.
A Phase 2a trial will assess the safety and immunogenicity of IDRI's TB vaccine candidate in 60 participants in South Africa, who have previously had active TB. The trial aims to reduce TB recurrence after treatment, a major threat to TB control programs.
Methane emissions from Arctic tundra increase when sea ice melts due to altered ocean temperatures and microbial activity. The loss of sea ice has a significant impact on the Arctic climate, leading to higher temperatures and increased methane production.
A research team at Northwestern University has developed a computational algorithm that leverages cells' noisy nature to control the networks governing cellular behavior. By controlling a smaller network of state transitions, they can promote cellular health and prevent disease.
The study found that Inuit have special mutations in genes involved in fat metabolism, which lower bad LDL cholesterol and fasting insulin levels. These mutations also reduce height by 2 centimeters in the Inuit, a finding associated with shorter heights in Europeans.
Research finds that rural adolescents are 35% more likely to abuse prescription painkillers in the past year compared to urban teens. The study suggests that limited medical care and emergency room prescriptions contribute to this issue.
A new study by researchers from Linnaeus University demonstrates that a higher degree of individual variation is beneficial to populations and species. The findings suggest that more variable populations are less vulnerable to environmental changes, show decreased fluctuations in population size, have superior establishment success, la...
A study found that African American women with breast cancer have a higher prevalence of aggressive tumor characteristics, including the TP53 driver mutation and basal tumor subtype, which contribute to racial disparities in survival rates. The research may help develop targeted therapies against these subtypes.
Researchers used integrated 'omics' approaches to analyze changes in proteins across different organs in young and old rats. They found that aging affects organs in strikingly different ways, with specific protein patterns related to the organ's unique cellular properties or function. The study suggests that aging is an organ-specific ...
A new study suggests that obese patients with type 2 diabetes may benefit from priority access to obesity surgery, as they often experience remission of diabetes and reduced complications. This can lead to lower accumulated drug costs and overall healthcare expenses.