The study reveals that the source of stem cells used for hematopoietic stem cell transplantation in patients with bone marrow failure varies worldwide. Bone marrow is predominantly used in the Americas and Europe, while cord blood and peripheral blood stem cells are more commonly used in other regions.
A new microscopy technique allows for 3-D imaging of single molecules, live cells, and developing embryos with reduced photo toxicity. The breakthrough enables the investigation of broader biological events, expanding the range of microscopes that can be used.
A National Institutes of Health study found that women who eat more potatoes before pregnancy may have higher rates of gestational diabetes compared to those who consume fewer potatoes. Substituting potatoes with other vegetables, legumes or whole grains may help lower gestational diabetes risk, according to the researchers.
The Society for Cardiovascular Angiography and Interventions has released a consensus statement providing guidance for treating patients with concomitant cardiovascular disease and cancer. The document aims to increase the competency of cardiovascular professionals in caring for cancer patients, who are expected to increase to 20 milli...
Researchers have identified alveolar macrophages as key contributors to cystic fibrosis airway inflammation, with the overabundance of XBP-1 protein mediating their inflammatory effect. This discovery bolsters the case for targeting this pathway in therapy.
A recent study reveals that a fungus has developed a way to infect triticale by combining DNA from wheat and rye mildew variants, compromising its natural resistance. This discovery highlights the importance of understanding evolutionary mechanisms in plant diseases.
A study by Washington State University found that black men's cumulative experiences over time motivate them to develop valuable skills in IT careers. These experiences give them a type of capital that is often less available to other groups, influencing their career choices and outcomes.
A new study reveals clouds trap heat on the Greenland Ice Sheet, raising its temperature by 2-3 degrees and accounting for up to 30% of ice melt. This findings could improve future climate models, helping scientists and policymakers adapt to sea level rise.
Neural clocks have been found to exist and can be used to predict timing behavior in rats. Researchers identified a mechanism in the Striatum brain region where populations of neurons create sequences of activity that encode time.
Researchers tested eggplant irrigation rates and found that moderate watering can reduce nitrogen leaching and maintain fruit yields. The study suggests a potential to lower current irrigation rates without negatively impacting crop performance.
A new study proposes that genetic drift contributes to the development of leukemia in young children. The researchers used a computational model describing blood stem cell population dynamics and found that drift plays a significant role in early-life leukemia formation. In contrast, selection drives leukemia development in older adults.
The brain initially represents and decides between competing action options by planning multiple movements simultaneously. Researchers found that participants planned a movement for each potential target and executed these movements simultaneously when the target was uncertain.
Scientists have developed a new strategy for constructing highly specific synthetic pores using DNA, which can control the release of therapeutics. The pores are designed to act like doors, opening only when provided with the right key, allowing for precise targeting of drugs to specific tissues.
Researchers at IUPUI have developed a new technique to detect illicit treatment of racing tires with volatile chemicals, finding approximately 15% of tires tested positive for banned substances. The method uses Headspace Solid Phase Microextraction (SPME) and Gas Chromatography/Mass Spectrometry (GC/MS), and has the potential to be app...
Researchers at Washington University School of Medicine suggest atherosclerosis is driven by processes similar to brain diseases like Alzheimer's and Parkinson's. Protein buildup inside macrophages, facilitated by p62, interferes with their ability to function.
A study of 102 infants found associations between the infant's gut microbiome composition and delivery method, as well as feeding practices. The research suggests that differences in the microbiome composition may be linked to short- and long-term health outcomes.
A UCLA-led study analyzed genome sequences of wolves, wild dogs, and domesticated dogs to find that domestication may have led to a rise in harmful genetic changes. This could be due to temporary population bottlenecks during breeding for desirable traits.
Cheyenne will be a critical tool for researchers studying climate change, severe weather, and other important geoscience topics. The new system will help scientists lay the groundwork for improved predictions of various phenomena, including thunderstorm outbreaks and solar cycles.
A study by ETH Zurich researchers found that teachers with less experience discriminate against female students in physics exams, leading to poorer grades. The findings highlight the importance of teacher training and objective grading criteria to combat biases and stereotypes.
Scientists at DOE national laboratories discovered a simple manufacturing technique to form cathode material into tiny, layered particles that store energy while protecting themselves. This technique, called spray pyrolysis, is cheap and widely used, and could lead to cheaper and higher capacity lithium-ion batteries.
Researchers from Wake Forest Baptist Medical Center reviewed the scientific evidence for top-selling over-the-counter dietary supplements sold to improve male sexual health. While some natural supplements show promise, they lack robust human evidence and can be pure or weak.
Stanford researchers developed a lithium-ion battery that can be shut down by heating and restarted when the temperature cools. The new technology uses nanospikes to prevent overheating and reduce the risk of fires in batteries powered by devices like hoverboards and computers.
A study by Tufts University researchers found that high folic acid intake causes a lowered immune response in aged mice, particularly affecting natural killer cells. The study used an aged mouse model and found that excess folic acid impaired NK cell development, leading to reduced immunity against viral infections and cancer.
The article argues that parental permission is not required ethically and may hinder public health interests, as adolescents account for 26% of new HIV infections. The authors propose strategies to address state minor-consent laws and institutional review board interpretations.
Research teams confirm biennial mammography for women aged 50-74 offers favorable balance of benefits to harm. Screening frequency impacts mortality and false positives, with biennial screening reducing breast cancer deaths by 25.8%.
Researchers found that mothers' appetites impact on offspring's appetites, stabilizing population sizes. This helps prevent extinction and counteracts the effect of large numbers being preyed upon.
Researchers have successfully used digital imaging to measure pyrethrum flowers before harvesting, detecting 88% of flowers compared to manual recognition. This automated system allows for faster and easier image collection, enabling greater plot areas to be sampled for yield estimation.
Researchers developed a process to create a water-loving polymer with structure, opening up possibilities for artificial blood vessels and soft tissue-like mechanical properties. This breakthrough addresses the challenge of balancing hydrogel's water-loving nature with the need for crystallinity.
A new meta-analysis reveals that hookah smokers inhale a large load of toxicants, with one session delivering 25 times the tar and 125 times the smoke of a single cigarette. The study suggests that hookah tobacco smoking should be monitored more closely to address this growing health concern.
Dr. John Michael Criley receives the 2016 Distinguished Teacher Award for his innovative and compassionate teaching, training over 2,200 cardiologists and medical professionals worldwide. He has made significant contributions to cardiovascular medicine through his research papers and textbooks.
Transforming primary care practices into 'medical homes' requires substantial investments, with median one-time costs ranging from $7,694 to $117,810 per practice. Ongoing costs include adding staff and investing in information technology, constituting a significant financial burden for small medical practices.
Berkeley Lab researchers have discovered a technique called spray pyrolysis that can improve the performance of lithium nickel manganese cobalt oxide (NMC) cathodes, which are crucial for electric vehicle applications. By controlling surface chemistry, they were able to reduce surface reactivity and increase material stability.
The PhD project plan aims to publish outputs from the whole research cycle using an open science approach. It focuses on digitizing scholarly papers and data, making them more accessible and citable, and ensuring reproducibility.
A University of Cambridge researcher warns that abandoning carbon capture and storage (CCS) would hinder efforts to reduce carbon emissions. CCS is essential for delivering flexible power and reducing emissions from industrial processes, but funding issues have led to a decline in interest from corporations and governments.
EPFL scientists have developed a gel that boosts the ability of normal cells to revert into stem cells by simply squeezing them into shape. This method paves the way for large-scale production of stem cells for medical purposes, offering new ways to treat injuries and diseases such as Parkinson's and diabetes.
A new study published in Circulation journal found that drinking sugar-sweetened beverages daily increases visceral fat, a type of body fat that affects diabetes and heart disease risk. The study showed a direct correlation between greater sweetened beverage consumption and increased visceral fat among middle-aged adults.
Researchers at Cedars-Sinai are working on a new risk assessment tool to identify patients susceptible to sudden cardiac arrest. The goal is to predict those at risk for the fatal heart rhythm malfunction, which claims 350,000 lives annually in the US.
The article highlights the importance of stakeholder involvement in ESS research and governance, citing experiences from transdisciplinary projects in Asia, Africa, and Europe. Successful participation depends on socio-cultural context and requires different means and modes of participation during different project phases.
A team of researchers is exploring the use of the NAO robot in a new approach to pediatric rehabilitation based on social interaction between robots and humans. The robot can read moods, recognize family members, and learn preferences, providing personalized interventions for children with motor disabilities.
A new study by Ohio State University researchers found no link between eating healthy foods and avoiding unhealthy options in preschoolers. Despite frequent consumption of fruits, vegetables, and milk, children were just as likely to eat high-sugar, salty, and fatty foods.
A University of Michigan study found that nisin can kill 70-80 percent of head and neck tumor cells in rats and extend survival. Nisin also fights deadly bacteria such as MRSA, using its ability to bind to bacteria and kill biofilms.
A Yale University study found that the hormone FGF21 protects against age-related loss of immune function by promoting T cell production. Increasing FGF21 levels may be an additional strategy to bolster immune function in the elderly or cancer patients undergoing bone marrow transplantation.
UCLA scientists have discovered a crucial role for the Rbfox1 gene in regulating genes that contribute to autism risk. The study highlights an untapped region in brain cells as a goldmine of drug targets for new treatments.
Researchers at Northwestern University have developed a way to train smartphone activity trackers to spot fake activity, increasing accuracy from 38% to 84%. The system learns to recognize patterns of cheating, such as shaking the phone while lounging on the couch, and can generalize it across individuals.
Researchers created an audio platform that modifies voices to sound happier, sadder or more fearful, and found participants' emotional state changed accordingly. The study suggests people don't always control their own voice to match emotions, but listen to it to gauge feelings.
Researchers identified a pivotal role of the Miz1 protein in determining tumor identity and its interaction with Myc proteins driving group 3 medulloblastoma. The study suggests targeting the Miz1-Myc complex may suppress the spread of group 3 tumors.
A quick screening method has been used to identify and test promising anti-Ebola drugs. The method, which allows for the evaluation of candidate drugs and comparison of antiviral effectiveness, has shown potential in reducing the emergence of drug resistance and increasing confidence in experimental results.
A study by University of California, Riverside scientists reveals that backyard chickens have a higher diversity of ectoparasites, including six species of lice, the northern fowl mite, scaly leg mite, and chicken red mite. This finding suggests that the benefits of backyard chicken keeping may come with an itchy price.
Eftekharnejad's research will investigate the impacts of data intrusion on phasor measurement units (PMU) devices and propose mitigation strategies for power grid security. The study aims to identify critical components targeted by cyberattacks and develop methods to mitigate cascading blackouts.
Recent University of Cincinnati research on ancient burial practices in pre-Roman Italy sheds light on economic and social mobility, military service, and drinking customs. The study found strong social stratification and hierarchy, as well as commonality of military service among men's tombs.
Tropical Cyclone Ula has weakened from a Category 4 Hurricane to a Category 2 hurricane due to unfavorable environmental conditions. The storm is expected to make its closest approach to Kingston Island and then move north of New Zealand by January 12.
A non-tropical low pressure system with potential subtropical characteristics has developed in the Northern Atlantic, producing hurricane-force winds and gale-force conditions. The system is expected to produce hazardous marine conditions over parts of the central and eastern Atlantic for several days.
A new study reveals that giant icebergs in the Southern Ocean contribute significantly to carbon sequestration, with enhanced phytoplankton productivity extending hundreds of kilometers beyond the iceberg's length. This process helps slow global warming by storing atmospheric carbon dioxide.
A study by the Canadian Medical Association Journal found that five percent of Ontarians account for 65% of provincial health care costs, with the top 1% accounting for one-third of these costs. The study tracked $30.5 billion in healthcare spending, which is about 75% of total government health expenditures.
CyVerse rebranded from iPlant Collaborative to emphasize its expanded mission across all life sciences. The platform provides data management and computation services for various scientific disciplines.
Rice University scientists develop a self-adaptive composite that heals itself and returns to its original form after compression. The material, called SAC, combines self-healing and reversible self-stiffening properties.
The University of Illinois and Syngenta have signed an agreement to implement a commercialization strategy for the 'RIPE' project, which aims to improve photosynthetic efficiency in food crops. The partnership brings together academic groups with industry partner Syngenta to advance technologies developed under the project.
A multi-institutional international study has revealed new information about the interaction between long non-coding RNAs and HIF-1 signaling pathways in triple-negative breast cancer. The study identifies four previously unknown phosphorylation sites, which predict a worse outcome for TNBC patients, suggesting that these sites could s...
Research studies examine the viability of small, solo family practices in rural areas, finding they often provide vital care. Large independent primary care groups are also shown to be attractive options for physicians and patients, offering resources and autonomy while reducing costs.
Researchers at Institut Pasteur in French Guiana have sequenced the complete genome of the Zika virus, showing almost complete homology with strains responsible for the 2013-2014 Pacific epidemic. The analysis provides a major starting point for understanding how the virus behaves and shedding light on its impact.