A new study found that AMH levels are related to high testosterone secretion and abdominal adiposity, making it a possible surrogate for ovarian antral follicle number. Additionally, AMH levels were correlated with age and body mass index, indicating its potential as a biomarker for PCOS diagnosis in obese adolescent girls.
New research from South Korea suggests that higher dietary calcium intake may lower the risk of cardiovascular disease in older people, but not stroke and fracture risk. In a population with low calcium intake, higher dietary calcium was significantly associated with decreased risk of CVD.
Researchers have discovered a new potential therapy that can protect transplanted human pancreatic islets from dying. The study suggests that pretreating cells with a peptide hormone called cholecystokinin (CCK) may enhance the curative potential of islet transplant for Type 1 diabetes.
A new study found that combining a temporary intestinal bypass device with the drug liraglutide improves diabetes control and weight loss in patients. The combination treatment resulted in significant weight loss (12.8 kg) and improved glycated hemoglobin levels compared to other treatments.
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Researchers at Northwestern University developed an ovary bioprosthesis implant using a 3D printer, allowing mice to bear live young after ovary removal. The technology aims to restore fertility and hormone function in women affected by cancer treatments or born with reduced ovarian function.
Researchers investigate how changes in light exposure may contribute to breast cancer development. Extended periods of nighttime illumination disrupted normal cellular behaviors and gene expression, particularly in hormone-dependent tissues like the breast.
A study of nearly 4,000 children found that infants with high BMI as young as 4-6 months are at risk of early-childhood obesity. Infants with BMI above the 85th percentile by 6, 12, or 18 months are strong predictors of severe obesity by age 6.
A study from Intermountain Medical Center Heart Institute found that low levels of both total vitamin D and bioavailable vitamin D are associated with poor cardiovascular outcomes, including heart attacks. The research evaluated 4,200 participants and discovered that measuring these two components is crucial in predicting major adverse...
Whey protein diet participants lost the most weight and experienced reduced hunger and glucose spikes compared to other diets. The study found that a high-protein breakfast containing whey protein induced greater satiety and reduction of glucose spikes after meals.
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Researchers found that brominated fire retardants stimulate an adrenal gland hormone, leading to potential development of cardiovascular disease. The study's results suggest a link between these chemicals and high blood pressure, cardiac hypertrophy, and congestive heart failure.
A new study suggests that liraglutide, a diabetes drug, reduces the brain's reward response to high-fat foods, making them less desirable. This effect may be beneficial for individuals with Type 2 diabetes who tend to overindulge in fatty foods as a coping mechanism.
A study published in the Endocrine Society reveals that anabolic steroid abuse is associated with severe blood pressure increase and hypertension. The research found that daytime and nighttime blood pressures were higher among ongoing AAS abusers compared to former abusers and non-users.
A study of 41 male veterans found that blast concussions frequently result in hormone changes, causing problems like fatigue, depression, and poor quality of life. Researchers detected hypopituitarism in 44% of affected veterans, with those experiencing hormonal abnormalities showing poorer sleep quality and increased depressive symptoms.
A new study found that estrogen replacement therapy improves verbal memory and cognitive flexibility in young female athletes with amenorrhea. The study showed significant improvements in both immediate recall of words and ability to switch between tasks, even when controlling for age and pre-treatment test scores.
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A new study from Brazil found that skin tanning protects against harmful UV irradiation but limits the skin's ability to produce vitamin D. The study, which evaluated 986 participants, showed that 72% had vitamin D deficiency and most people exposed to high levels of sunlight were deficient.
A global trial showed statins alone reduced adverse cardiovascular events in people with average cholesterol and blood pressure, while blood pressure-lowering medications were only beneficial in those with hypertension. The study suggests statins can be used more widely to prevent heart disease.
SourceAmerican College of Cardiology·JournalNew England Journal of Medicine·DateApr 2, 2016
Research from Australia suggests that women with PCOS report a higher prevalence of asthma, which is also linked to excess weight. The study found that PCOS status and body mass index were independently associated with asthma.
A new study found that those who lose more weight are most likely to keep it off, but also experience weight cycling. Patients who lost high percentages of their initial body mass index (BMI) were more likely to maintain their weight loss over time.
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Researchers from San Diego State University have developed a portable balance board called BTrackS that provides fast, objective feedback on an athlete's balance disruption following a suspected concussion. The technology has been found to be about twice as effective as the most widely used balance test for concussion nationwide.
SourceSan Diego State University·JournalInternational Journal of Sports Physical Therapy·DateApr 2, 2016
Steroid medications like prednisolone suppress brown fat's activity, leading to weight gain and obesity. Researchers found that steroid use increases energy storage from food instead of burning it through brown fat.
A study found that oxytocin nasal spray decreases impulsive behavior in overweight men, allowing for better self-control and reduced food intake. The treatment showed promising results with minimal side effects, suggesting a potential new approach to treating obesity.
A recent study published by The Endocrine Society found that radioactive iodine treatment can impair a woman's remaining egg supply, known as ovarian reserve. Women who received high doses of radiation had significantly lower levels of anti-Müllerian hormone (AMH) after treatment.
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The American Society for Biochemistry and Molecular Biology honored prominent researchers with various awards, including the Herbert Tabor Research Award, FASEB Excellence in Science Award, and ASBMB Plenary Lectures. These recognition include notable scientists such as Robert G. Roeder, Bonnie L. Bassler, Peter Walter, Charles Brenner...
SourceAmerican Society for Biochemistry and Molecular Biology·DateApr 2, 2016
A Paleolithic-type diet improved insulin sensitivity, reduced abdominal adiposity and body weight in obese postmenopausal women. The diet high in polyunsaturated fatty acids may have long-term beneficial effects on obesity-related disorders.
A recent study published in the New England Journal of Medicine found that taking statins and antihypertensives can reduce cardiovascular disease events by 25-30% in patients at intermediate risk. The research also suggests that combining these medications can be an effective way to prevent heart attacks and strokes globally.
SourceMcMaster University·JournalNew England Journal of Medicine·DateApr 2, 2016
A non-inferiority trial found TAVR to be at least as safe and effective as surgery in intermediate-risk patients with severe aortic stenosis. The study showed similar rates of death and disabling strokes after two years, but TAVR patients had shorter hospital stays and lower major complications.
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The study found that women have a significantly higher prevalence of peripheral artery disease, while men have a higher prevalence of carotid artery stenosis and abdominal aortic aneurysms. Diabetes is also identified as a major risk factor for developing PVD, even in patients without heart disease.
SourceNYU Langone Health / NYU Grossman School of Medicine·DateApr 2, 2016
A recent study found that patients with severe, symptomatic aortic stenosis who underwent transcatheter aortic valve replacement (TAVR) with the SAPIEN XT device had similar two-year clinical outcomes to those who underwent surgical aortic valve replacement. Additionally, TAVR was associated with reduced severe bleeding, length of stay...
SourceUniversity of Pennsylvania School of Medicine·JournalNew England Journal of Medicine·DateApr 2, 2016
A new study found that effectively treating depression can reduce a patient's chance of having a stroke, heart failure, a heart attack, or death. Effective treatment for depression reduces a patient's heart risks to the same level as those who never had short-term depression.
Researchers found that a new low-dose vaginal estrogen capsule significantly improved symptoms of menopausal vulvar and vaginal atrophy in postmenopausal women. The treatment, TX-004HR, showed improvement in vaginal cell regeneration, pH levels, and painful sexual activity.
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A recent study of nearly 3,000 patients found that elevated levels of glycoprotein acetylation (GlycA) offset the benefits of high-density lipoprotein (HDL) cholesterol in preventing heart disease. Inflammation of artery walls is a contributing factor to heart attacks and strokes.
A new study from Intermountain Medical Center and Johns Hopkins Hospital found that abdominal obesity, or having an apple-shaped body, is a strong predictor of serious heart disease in diabetic patients. Waist circumference was also shown to be a stronger predictor of left ventricular dysfunction than total body weight or BMI.
A study of nearly 8,500 people found that low thyroid function increases the risk of developing Type 2 diabetes by 13%, with a higher risk for those already with prediabetes. Screening for thyroid function may be beneficial in individuals at risk of developing diabetes.