Researchers discovered that neutrophils can internalize C. neoformans in the brain vasculature and circulate them back into the bloodstream for removal. This process enables the prevention of cryptococcal meningoencephalitis, a deadly brain infection.
Researchers at McGill University discover that cyanuric acid can coax DNA into forming a triple helix, unlike the familiar double helix. This breakthrough could lead to the creation of new DNA structures with unique properties.
Research reveals depression alters oxidative stress levels, leading to increased risk of cardiovascular disease and cancer. Treatment can improve malondialdehyde levels, while zinc and uric acid levels normalize.
In this experiment, participants were asked to discover successive innovations to produce a virtual remedy and stop the spread of a virus. The results show that fully connected groups performed well in the short-run but rapidly converged toward the same solutions.
Most aquatic species sense sound via particle motion, yet few studies have included measurements. Researchers from the University of Exeter and others have developed user-friendly tools to maximize its uptake and understand the impact of man-made noise on aquatic life.
A recent study published in the Academy of Management Journal found that employees who work for consistently unfair supervisors are less stressed and more satisfied than those with erratic bosses. The researchers suggest that prioritizing self-discipline and careful thinking can help deliver leaders who treat employees fairly most of t...
Researchers analyzed the oldest known penguin fossil and found no significant changes in brain structure compared to modern penguins. The study suggests that becoming flightless did not directly impact brain anatomy, contradicting previous assumptions.
Scientists have made significant breakthroughs in understanding the ocean's role in absorbing carbon dioxide from the atmosphere. Using satellite and ship measurements, they found that around a quarter of the CO2 released into the atmosphere ends up in the oceans, equivalent to two million double-decker buses or 72,000 Boeing 747s annu...
A new study by Northwestern University research found that low levels of vitamin D are associated with aggressive prostate cancer in men. Men with dark skin or limited sun exposure should get their vitamin D levels checked and supplement if necessary to reduce the risk of aggressive prostate cancer.
Researchers at Saarland University have developed a system that enables players to interact with each other and the game using spoken language, despite speaking different languages. The Dialog Box uses AI-powered voice interactions to facilitate collaboration and problem-solving among team members.
A new NASA study reconstructs the Mediterranean's drought history using tree rings, finding that the eastern region has experienced its worst drought in 900 years. The research provides a 'fingerprint' for identifying human-induced climate change contributions and will improve computer models simulating climate change.
A novel Ebola virus-encoded microRNA-like fragment serves as a biomarker for early diagnosis of Ebola virus disease (EVD). This fragment was found to be detectable in the blood of patients before the development of viremia, suggesting its potential to advance the diagnosable window for EVD.
A Baylor University study found that people with an inner sense of attachment to God are more emotionally committed to their workplace and satisfied with their jobs. This attachment is linked to higher levels of job commitment, satisfaction, lower absenteeism, and conflict, as well as stronger coping skills.
Researchers found that early MRI screening can reduce breast cancer mortality in female survivors of childhood Hodgkin's lymphoma who received chest radiation. The study suggests that starting screening at age 25 with MRI can be more effective than mammography, but may lead to false positives.
Researchers discovered novel genetic variants in a hormone receptor-positive male breast cancer patient, which led to a prolonged stable disease. The study provides new insights into the genomic landscape of male breast cancer and suggests potential benefits of combining treatments to block the PI3K/Akt/mTOR pathway.
Scientists René Heller and Ralph Pudritz suggest focusing on Earth's transit zone, where our planet passes in front of the sun, to maximize the chances of detecting signals from extraterrestrial observers. The proposed method involves studying the dimming of starlight as a planet crosses its host star's face.
A recent study found that 53% of lawn mower injuries to children require amputation. The most common injury sites were the lower extremity and collisions with mower blades. To mitigate these risks, researchers recommend increased education campaigns for parents on how to keep their children safe from lawn-mower injuries.
A recent study by Sam Houston State University found that up to half of college students experience intimate partner violence, emphasizing the need for campus safety planning. The research brief highlights the importance of educating students on personal safety strategies and providing access to resources for victims of abuse.
A new study is exploring whether the drug Omalizumab can be targeted at specific patients with severe asthma, who are expected to benefit most from the treatment. This research aims to identify biomarkers that will enable more effective treatment and improve symptoms for those suffering from severe asthma.
A recent study found that severe anemia is a significant risk factor for necrotizing enterocolitis in VLBW infants, while red blood cell transfusion was not significantly related to the development of NEC. This suggests that preventing severe anemia may be more important than minimizing RBC transfusion exposure as a strategy to decreas...
Researchers propose that a universe with diverse body sizes reduces gravitational tension faster due to the natural tendency of systems to evolve toward reduced tension. This phenomenon is a manifestation of the Constructal Law, which states that natural systems facilitate flow.
A new study published in Sleep shows that patients with obstructive sleep apnea experience high satisfaction rates with telemedicine-based care. The study found no significant differences between functional outcome changes and objectively measured PAP adherence when using either in-person or telemedicine visits.
A study of 5,566 older workers found that those in sales, office-support and service occupations had more risk factors for heart disease and stroke than management or professional jobs. Workers in these professions had higher rates of smoking, poor eating habits and lower levels of physical activity
The article highlights regional differences in demographics, disease prevalence, and cultural attitudes towards donated tissues and organs. Regulatory approaches vary across countries, necessitating a tailored approach to balance risk and benefit.
A new study suggests that Middle East Respiratory Syndrome coronavirus (MERS-CoV) develops mutations that make the virus less virulent during an outbreak, challenging current vaccine strategies. The study found two specific point mutations in the viral spike protein that impaired fitness and virulence.
A study using molecular simulations suggests that polyunsaturated lipids can alter the binding rate of dopamine and adenosine receptors, affecting cell function in neurodegenerative diseases. This discovery could lead to new therapeutic pathways for regulating receptor binding.
Researchers found that small increases in social spending can reduce the risk of dying from various causes, including coronary heart disease. Welfare spending was shown to lower mortality by nearly 3 percentage points per $250 spent per person per year.
A randomized controlled trial found that vitamin D supplements during pregnancy have no significant effect on the bone density of babies. However, further analysis suggests that supplementation may counteract the seasonal drop in vitamin D levels caused by lack of sunlight, potentially improving bone health in winter-born babies.
Researchers identified a novel syndrome resulting from multiple genomic lesions in two male siblings with similar phenotypic features. Whole exome sequencing and cytogenetic testing revealed terminal duplications of Chromosome 16q and deletions of Chromosome 5p, which likely contribute to the complex clinical presentation.
Scientists have made a breakthrough in understanding enzymes that break down tough biomass, crucial for producing biofuels from renewable sources. The discovery could lead to improved efficiency and environmental sustainability in industrial biofuel production.
Scientists have discovered that some human fat cells originate from stem cells in bone marrow, which could lead to new strategies for preventing and reversing fat-related chronic diseases. By manipulating the production of these cells, researchers hope to reduce the risk of conditions like cardiovascular disease and obesity.
A recent study by University of Illinois researchers found that conservation aid alone has not prevented deforestation in sub-Saharan Africa. The study suggests that in some cases, conservation aid may have exacerbated forest loss due to displacement of forest clearing activities outside protected areas.
Researchers found that reducing fruit and vegetable prices could decrease cardiovascular deaths by 1.2% in five years, while increasing sugary drink prices could lead to a 0.25% decrease in heart attacks. Implementing such policies nationwide could potentially prevent 515,000 deaths from cardiovascular disease.
Researchers found that dominant animals cannot stop subordinate breeding, leading to violent eviction events. Mass evictions result from high reproductive competition, often involving multiple females and males being kicked out of their family groups.
Researchers identify IRF4 as the first gene associated with greying hair, revealing a genetic link to human aging. The study analyzed 6,000 people from diverse ancestry, uncovering additional genes influencing hair shape, curliness, and density.
Pregnant women with asthma may be at greater risk of preterm birth due to exposure to high levels of traffic-related air pollutants like nitrogen oxides and carbon monoxide. Early exposure, particularly in the months leading up to conception and during early pregnancy, was found to increase preterm birth risk by nearly 30%.
A new process of moving donor management out of hospitals to freestanding facilities has been shown to be more efficient and cost-effective. This approach results in a higher number of suitable organs being recovered for transplant, with an average increase of 3.4 organs per donor.
A new study by Duke University warns that China's coal-based chemical industries will significantly increase the country's carbon footprint. The industries, which include synthetic fuels and olefins, emit nine times more CO2 than alternative methods.
Research shows that 32% of workers feared losing their jobs, while 38% were anxious about pay cuts. The study found that working in the public sector made staff more likely to fear job losses, while being over 35 and working in routine or semi-routine jobs increased fears of worsening working conditions.
Researchers studied the 2014 EV-D68 outbreak, finding that confirmed infections grossly underestimates the true burden on children's hospitals. The study highlights the importance of resource utilization monitoring in future unexpected outbreaks.
Scientists will simulate an emission from a submerged carbon dioxide storage reservoir in the North Sea, using acoustic and chemical sensors to detect released CO2. The goal is to develop innovative technology for detecting and quantifying CO2 emissions in the marine environment.
A social amoeba uses DNA nets to trap and kill invading bacteria, a mechanism similar to that seen in mammalian immune cells. This discovery highlights the convergent evolution of immune systems across species.
A new study by University of Miami researchers identified a potential connection between attention-deficit/hyperactivity disorder (ADHD) and increased academic expectations in young children. The study found that rising academic demands since the 1970s may have contributed to the doubling of ADHD diagnoses over the past four decades.
Researchers have discovered a critical change in amyloid beta protein shape that explains why smaller bundles are more toxic than larger ones. This understanding may lead to developing drugs to treat diseases like Parkinson's and Type-II diabetes.
A study by Temple University researchers found that pharmaceutical companies can improve their performance by investing in commercial innovation and aligning their culture of execution. The study, published in the Journal of Medical Marketing, analyzed data from 26 large and medium-sized pharmaceutical companies.
A new survey of historical evidence reveals that Henry Gray plagiarized parts of the first edition of his book, Gray's Anatomy. The study examines traits of character that demonstrate Gray's inclination towards garnering credit at others' cost.
Patients aged under 45 and 75 years and older report greater pain and lower activity levels following TKR surgery. Despite comparable range of motion improvements across all age groups, these patients experience more challenges with daily activities.
A Duke University theorist proposes that the universe's varied body sizes are a result of internal tension release through hierarchical formation. This concept is rooted in Bejan's constructal law, which states that flowing systems will tend towards easier architecture by releasing tension through smaller, more numerous bodies.
Researchers used DFT to calculate electronic, elastic, and vibrational properties of BiAlO3. The study explores its crystal structure, space group R3c, and lattice parameter a = b = c = 5.338?A.
Researchers developed a microfluidic platform to assess dynamic deformability and adhesion of red blood cells in controlled microphysiological flow. The study found that non-deformable RBCs have increased adhesion at high flow shear stresses, suggesting an interplay between deformability and adhesion.
The ALCF-IASLC Joint Fellowship Award supports novel research with the potential to positively impact lung cancer patients. Dr. Robin Mjelle's project aims to develop a risk-prediction tool and serum poly-marker kit for early lung cancer detection, leveraging pre-diagnostic serum samples from Norway's HUNT biobank.
The USPSTF found convincing evidence that visual acuity testing can identify refractive errors, but inadequate evidence on the benefits of screening and detection. Early treatment of refractive error, cataracts, and AMD improves or prevents loss of visual acuity, with small harms from early treatment.
A new study reveals that patients with long-term urinary catheters attend emergency departments frequently due to catheter problems, but often lack community nurse support. The findings suggest that better strategies are needed to address and manage these issues in the community.
A study published in Journal of Social Science and Medicine found that older adults who participate in social activities, such as attending religious events, tend to get better sleep. This suggests that engaging in social connectedness can be an important factor for promoting healthy aging.
A novel psychiatric intervention called Attempted Suicide Short Intervention Program (ASSIP) has been shown to reduce the risk of suicide re-attempts by 80% in patients who have attempted suicide. The study found that ASSIP participants experienced a significantly lower rate of repeat attempts compared to those who received standard care.
A new simulation code was developed to accurately predict coronal mass ejections (CMEs) and their impact on space weather. The model successfully validated using observational data from the 2003 Halloween CME events, enabling accurate predictions of magnetic fields and arrival times.
A study published in JAMA found that physicians with highly educated spouses are significantly less likely to work in rural Health Professional Shortage Areas. Only 4.2% of married physicians with highly educated spouses worked in a rural HPSA, compared to 7.2% of those without such spouses.
Researchers at Johns Hopkins University found that expertise influences how people process visual information, with novices faster to identify letter pairs but less accurate. The study used the Arabic alphabet and showed participants 2,000 pairs of letters, revealing biases in expert perception that went beyond visual features.
The special theory of relativity has been found to be theoretically disproved, leading to questions about related physics theories. The paper reveals that experiments initially thought to demonstrate relativistic effects actually show null or incorrect results.
Researchers found that beta-blockers can decrease the invasive growth of aggressive breast cancer cells by blocking the beta2-adrenoceptor, a cell surface protein stimulated by adrenaline. This discovery suggests beta-blockers could be a useful adjuvant therapy for some aggressive breast cancers.