A research team at Georgia Institute of Technology identified a specific miRNA molecule that controls the genes governing chemotherapy resistance in human pancreatic cancer cells. Increasing this miRNA's level restored sensitivity to the drug in vitro, suggesting a potential therapeutic approach for battling chemotherapy resistance.
The Journal of Dairy Science has compiled two new collections of articles, one on stocking density for dairy cattle and the other on lactic acid bacteria. The stocking density collection includes 10 articles published between 2006 and 2015, while the lactic acid bacteria collection contains 30 articles published between 1962 and 2016.
A University of Exeter researcher has led a four-year project to develop starch-based gels using enzymes, aiming to improve industrial applications and consumer well-being. The research could also reduce production costs and CO2 emissions associated with conventional gel manufacturing.
NASA's RapidScat instrument measured surface wind speeds near 46.9 mph/75.6 kph northeast of the system's center in System 91L. The National Hurricane Center (NHC) noted that the system has a high chance, 90 percent, of becoming a tropical depression.
Researchers found that infants are better at learning words with repetitive syllables than those without. This bias may help explain why many baby-talk words have repeated syllables, such as 'choo-choo' and 'night-night'. The study suggests that repetition plays a key role in word learning from an early age.
Researchers analyzed genetic data from 3,726 African-Americans to estimate patterns of ancestry, finding that 82.1% had ancestors in Africa prior to transatlantic travel. The study reveals regional differences in ancestry, with southern US residents having a greater percentage of African ancestry than those in the North or West.
A study by Dr. Subhamay Ghosh and colleagues found that only 24% of pregnant women were tested for pregnancy before undergoing surgery, highlighting a significant gap in care. The researchers recommend increasing awareness and implementing standardized testing protocols to improve safety for mothers and babies.
Scientists at Brown University have discovered a molecular 'brake' that regulates melanin production in the eyes, skin, and hair. The study found that TPC2, a protein channel, reduces melanin production by increasing acidity in melanosomes.
Researchers from the University Freiburg have developed a new model of T cell activation, demonstrating that cholesterol prevents an immune response even when no antigen is present. The study reveals a specific interaction between cholesterol and inactive T cell receptors, regulating their conformation and activity.
A leading expert outlines a three-point plan to identify and eliminate all sources of lead exposure nationwide. The plan emphasizes finding lead hazards in homes and pipes, fixing them using proven interim methods, and funding efforts to hold accountable companies producing lead-contaminated products.
Research highlights factors necessary for successful apex predator recovery, including disease regulation and biodiversity maintenance. The study reveals that full recovery is the exception rather than the rule, with many species facing complex challenges in their recovery pathways.
A new gene, ANKRD55, has been discovered to play a significant role in the neuro-inflammation process of Multiple Sclerosis. The study found that genetic variants associated with MS increase the production of ANKRD55 transcripts in immune cells, suggesting a key gene involved in deregulation.
A 55-year-old man underwent a combined VCA and double-organ transplant procedure, combining a scalp and skull flap with a kidney and pancreas transplant from the same donor. The patient experienced excellent outcomes, including good cosmetic appearance of the transplanted scalp.
A University of Michigan study found little mother-child dialogue among preschoolers using media, such as TV and video games. Children with highly educated mothers who discuss media had more interaction.
A recent study by North Carolina State University and Ohio University found that college students with an 'alcohol identity' are more likely to experience drinking problems. The researchers also discovered that posting about alcohol on social media sites is a stronger predictor of these problems than actual alcohol use.
Scientists study the molecular structure of edible fats using X-rays, discovering that the ratio of solids to liquids affects a fat's properties. They also investigate the impact of replacing saturated fats with unsaturated alternatives on taste and texture.
Researchers at Kobe University have developed a metal-containing compound that transforms into a solid when exposed to light and returns to its original liquid form when heated. This substance has potential applications in photolithography technology and other fields, including printed circuits and 3D printing.
A new blood test has identified a subset of patients with stomach cancer who are most likely to respond to treatment. The test measures the number of copies of the FGFR2 gene in cancer DNA circulating in the bloodstream, revealing that tumours with many copies of this gene were particularly susceptible to an experimental drug.
Researchers at Indiana University argue that annual registration fees for plug-in vehicles are misguided due to their minimal impact on road infrastructure funding. The decline in federal tax revenue is primarily attributed to increased fuel efficiency and non-adjusted fuel taxes, not plug-in vehicles.
The DFG has approved a second funding period for TU Dresden's Collaborative Research Centre CRC 940, investigating the cognitive and neural mechanisms underlying self-control and volitional action. The centre aims to elucidate impairments of self-control in mental disorders such as addictions or eating disorders.
A new study reveals that Port Jackson sharks have distinct personality traits, including boldness and handling stress reactivity. These differences are repeatable in juvenile sharks and may influence their interactions with habitat and other species.
Researchers have developed a new method for synthesizing phenyl-substituted 3,6-Dihydro-2H-pyran derivatives with high enantiomeric purity. The results showcase the potential of this approach for producing pharmaceuticals and other valuable compounds.
Researchers discovered that hawk moths can smell floral volatiles using olfactory neurons on their proboscis. This allows them to select flowers with sufficient nectar, leading to successful pollination and seed production. The study highlights the importance of scent in flower-pollinator interactions.
A leading physician argues that family planning is highly cost-effective in reducing greenhouse gas emissions and advocates for voluntary family planning as a crucial strategy. Studies show that having one less child can reduce carbon legacy by up to 9441 tonnes, more than other eco-actions.
Researchers found that savvy traders obtain larger profits when trading in stocks of more connected firms. The study shows that companies with more connected boards perform better and can benefit from director networks. However, the integrity of directors is crucial to avoid information leaking out.
A recent imaging study found a subtle increase in brain tissue volume in certain regions of patients with schizophrenia, indicating the brain's ability to reorganize and fight the illness. The study suggests that despite severe damage, the brain may constantly attempt to rescue itself or limit the damage.
Engineers at University of Wisconsin-Madison created world's fastest stretchable, wearable integrated circuits, expanding Internet of Things capabilities. These powerful circuits can operate up to 40 GHz and are 25 micrometers thick, enabling biomedical applications like epidermal electronic systems.
A recent survey by The Associated Press-NORC Center found that only one-third of older Americans feel financially prepared for retirement. Many are anxious about their savings and rely heavily on Social Security, which is expected to be a significant source of income for the growing older population.
Researchers have synthesized a new drug, HA15, that reduces melanoma cell viability without being toxic to normal cells. This breakthrough discovery has the potential to improve treatment outcomes for patients with skin cancer.
Researchers aim to develop optimum alarm systems by analyzing alarm errors and predicting their occurrence. The new models will prioritize alarms that reflect urgent situations while balancing staff alertness with patient recovery concerns.
Researchers at UC Berkeley developed a faster and more efficient CRISPR-Cas9 editing method for mice, using electroporation instead of microinjection. The new technique resulted in higher success rates and reduced embryo damage.
Researchers at MIT have developed an algorithm that can build complex DNA nanoparticles automatically, allowing for a broader range of applications in fields such as vaccine development and gene editing. The algorithm, known as DAEDALUS, can build any type of 3D shape with a closed surface, including shapes with holes.
A study found that patients who listened to relaxing music before cataracts surgery experienced significantly reduced anxiety and required less sedation. Music-induced relaxation lasts for approximately 60 minutes after the music stops, making it a potential non-pharmacological method to reduce pre-operative anxiety.
A new study by University of Hawaii researchers found that dinoflagellates can stress copepods, reducing their energy for growth, reproduction, and lipid biosynthesis. This impacts the food source for young fish and potentially affects fisheries.
Scientists have discovered that Zika virus can infect and replicate in immune cells from the placenta without killing them. This finding may explain how the virus passes through the placenta of a pregnant woman to infect developing brain cells in her fetus.
A recent survey by NORC at the University of Chicago found that over half of older Americans plan to work past 65, with many reducing hours or switching careers. The study also highlights the growing size of the older population and its potential impact on the workforce.
Scientists at PNNL are part of a core group advising the White House on microbiome research. The National Microbiome Initiative aims to study microorganisms' impact on climate science, food production, and human health.
A new UCLA study found that teenagers' brains activate the same reward circuitry when seeing high and low social media likes, influencing their behavior. The study suggests that social media can have a significant impact on teens' willingness to conform and engage in risk-taking behavior.
A clinical study confirmed a strong correlation between minor heart rate irregularities and the survival prospects of heart attack patients. The new method, measuring respiratory sinus arrhythmia, produces a specific picture of the body's functional condition.
Researchers at NCBS discovered Septin 7 as a 'molecular brake' regulating Orai proteins and maintaining dopamine levels. This discovery could lead to therapies for neurodegenerative disorders and immune system dysregulations.
A study by researchers at Duke University found that coal from the Appalachian Mountains contains the highest amounts of rare earth elements. The team identified ash from this region as a potential source for extracting these critical materials, which are essential for clean energy and emerging technologies.
A new study published in the journal Sleep found that US military members who reported insomnia symptoms or short sleep durations were less resilient than those with healthy sleep hygiene. The study also showed that poor sleepers are more likely to leave the military early and are less likely to deploy.
A University of the Pacific professor argues that pharmacists must be part of the solution to curb opioid abuse, citing a grim diagnosis of increased misuse and alarming numbers of overdose deaths. The expert advocates for independent education and broader pain management training for prescribers and patients.
A new study found that pediatric end-of-life care requires improvement, with 62% of parents' wishes for their child's death location not being fulfilled. Siblings also need more support after a family member's death, and healthcare staff experience logistical barriers to providing adequate bereavement care.
Researchers demonstrate how state-of-the-art quantum simulations with trapped ions can be used to solve complex problems like number-partitioning. By applying a strategy known as quantum annealing, they show a faster solution than other methods.
Kamesh Subbarao, a UTA aerospace engineer, has received a $201,000 grant from the Air Force Research Laboratory to develop an algorithm for cooperative control of multiple spacecraft. The algorithm aims to address uncertainties and time delays in data transmission, enabling better analysis of collected data.
A new study found that vitamin nicotinamide riboside (NR) can protect mice from diabetes complications by lowering blood sugar levels, reducing fatty liver, and preventing peripheral nerve damage. NR is a precursor to NAD+, an important cellular metabolite required for energy conversion.
A team of Australian researchers has discovered the fossilized remains of a bizarre group of carnivorous marsupials that lived 15 million years ago. The newly found species, Malleodectes mirabilis, had an insatiable appetite for snails and was characterized by its powerful hammer-like premolar.
Scientists discovered new natural products in the fungus Aspergillus fumigatus, which share similar biosynthesis pathways with plant isoquinoline alkaloids. The findings open up new roads for combinatorial biotechnology to develop novel active compounds and urgently needed new drugs.
Researchers at University of Waterloo created a 3-D simulation to study mode-2 internal waves that carry materials over long distances. The larger the wave bulge, the more material is carried, but instability can cause loss behind the wave.
Researchers found that Zika virus can infect human placental macrophages, known as Hofbauer cells, which have direct access to fetal blood vessels. This infection may allow the virus to cross the placental barrier and enter the fetal circulation, posing a risk to fetal development.
Research from UiT The Arctic University of Norway suggests that methane emissions from the seabed in the Arctic Ocean do not significantly affect the atmosphere. Scientists performed measurements near the seabed, in the ocean and atmosphere, to determine if methane is being released into the air.
A study found that only 52% of cancer patients received palliative care as recommended, highlighting the need for improvement in end-of-life care. Hospice care was more accessible to veterans than non-veterans, but disparities persisted.
A U of T Engineering team has designed a simpler way to keep therapeutic proteins localized for long periods. They found that proteins can be released over several weeks without encapsulation by controlling electrostatic interactions between proteins and nanoparticles.
A new tool by Japanese researchers predicts the risk of Zika virus importation and local transmission for 189 countries, identifying subtropical and tropical nations as high-risk. Countries with a history of dengue and other mosquito-borne diseases face the greatest risk of infection.