Researchers at Hospital for Special Surgery have identified a population of stem cells called ADSCs that are reduced in number in the layer of fat sitting under the skin in patients with scleroderma. The study found that replenishing these cells with antibodies may reverse the fibrosis characteristic of the disease.
A new study published in JAMA Pediatrics found a consistent association between bedtime media device use and inadequate sleep quantity, poor sleep quality, and excessive daytime sleepiness in children. Children who had access to but didn't use media devices at night also experienced similar sleep problems.
A new research paper suggests that the impact that formed the moon also caused calamitous changes to Earth's rotation and tilt. The model indicates that the remaining anomalies in the moon's orbit are relics of the Earth-moon system's explosive past, with a large tilt of up to 80 degrees.
A new study from the University of Chicago Medicine found that social media platforms can effectively inform young physicians about proper antibiotic use, improving their knowledge and behavior. The strategy successfully directed medical residents to relevant clinical pathways, resulting in a significant increase in correct usage.
A new paper from Northwestern University researcher Adam Safron suggests that orgasm is linked to synchronized brain activity and neural entrainment, producing a sensory absorption and trance-like state. This understanding could change the way people view their sexuality, emphasizing the role of rhythmic aspects in sexual experiences.
A major international study found that drug-eluting stents are equally effective as bypass surgery for patients with left main coronary artery disease, with fewer complications. The EXCEL trial followed 1,905 patients and showed stents to be safer in the first 30 days after treatment.
Researchers used social media platforms to map locations of highly sought natural destinations. These findings can inform management decisions and prioritize conservation efforts, leveraging the collective value placed on these areas by the public.
Researchers at UCSB explore the delicate balance between coherence and control with a simple yet complete platform for quantum processing. They successfully integrated the control of three superconducting qubits, creating an artificial magnetic field that allowed photons to interact strongly with each other and the pseudo-magnetic field.
A study of 12 million Facebook users found that using the platform is associated with living longer, particularly for those who maintain real-world social ties. Moderate online activity complements offline interactions, while excessive online time is linked to a higher risk of mortality.
Researchers discovered a neural circuit in fruit flies that creates an internal representation of direction and velocity, allowing them to navigate accurately. This finding has implications for our understanding of self-movement perception in humans and other animals.
Researchers at Seoul National University have developed a new method to make convertible displays that achieve near-viewing capabilities without the need for eyewear. This technology simplifies and shrinks the architecture of the display, allowing for closer viewing distances and practical applicability to mobile devices.
A new study suggests that a widely available web-based program can help cancer survivors reporting cognitive symptoms. The 15-week program improved self-reported cognitive function, lowered anxiety and depression, and improved fatigue. Objective neuropsychological function test results were not different between the two groups.
Researchers discovered two distinct mechanisms of cell extrusion from epithelial sheets, with low-density cell crawling and lamellipodia extension being the predominant mechanism at low cell density, while purse-string contraction takes over at high densities.
A researcher at UTA is working on big data mining tools to integrate patient data for better prediction of clinical outcomes and treatment of diseases like cancer. The project aims to find biomarkers using image-omics and data-based techniques.
The Penn Dental team has created a genetic engineering method to improve plant-based medicines by optimizing codons in DNA sequences. This technique resulted in increased protein expression levels, with hemophilia clotting factor five to six times higher and poliovirus protein roughly 26 times higher than native sequences.
A study published in the Journal of the American College of Cardiology found that white coat hypertension is associated with an increased risk of heart disease in older patients. Researchers analyzed data from over 650 patients and found that those diagnosed with white coat hypertension were more likely to experience cardiovascular eve...
A study published in Nature Neuroscience found that nerve cells dedicated to hearing rely on surrounding context to properly interpret and react to familiar sounds. Researchers observed patterns based on a basic divide in the nature of nerve cells, with excitatory and inhibitory neurons working together to balance brain activity.
Current system may not detect outliers in surgeon performance, as low caseloads limit statistical power to identify high mortality rates. The analysis suggests that more meaningful outcome measures, such as patient satisfaction and functional health status, are needed for accurate evaluation.
A new study reviewing 20 existing studies found that bedtime use of media devices increases the likelihood of inadequate sleep quantity, poor sleep quality, and excessive daytime sleepiness. The presence of a media device in the bedroom also affects sleep, even without use.
A study published in CMAJ found that telemedicine, including text messaging and web portals, can effectively manage diabetes by monitoring blood sugar levels and motivating patients. The use of interactive formats such as web portals or text messaging was most effective in controlling HbA1C levels.
Researchers found that observers on aerial surveys miss some large animals, like elephants, due to factors such as herd size and habitat type. Their study suggests population estimates from aerial surveys are biased low by 13 percent, highlighting the importance of accurate counting for conservation efforts.
Low-level clouds in the tropics cool the planet by reflecting solar radiation, but their impact on climate depends on spatial pattern. The study suggests that recent observed trends may underestimate global warming due to increased carbon dioxide.
A team of researchers presented a new model for the origin of Saturn's rings based on computer simulations. The study found that Kuiper belt objects were destroyed by tidal forces when passing close to giant planets, forming icy ring systems. This process explains the compositional differences between Saturn and Uranus' rings.
A SWOG study found widespread detection bias in prostate cancer biopsies, affecting younger, healthier men and those with family history or elevated PSA levels. Biases led to inconsistent results on risk factors, highlighting the need for rigorous data analysis and caution against assumptions.
A study published in Gynecologic Oncology found that less than half of cervical cancer patients receive standard-of-care treatment, highlighting the need for improved access. Patients who received brachytherapy had better overall survival rates compared to those receiving only two components of SOC.
A University of British Columbia-led review of mind-wandering research provides a new framework for understanding thought dynamics, potentially improving mental illness diagnosis and treatment. The framework suggests that spontaneous thought processes, including mind-wandering, are essential for creative thinking and dreaming.
A recent study estimated lake-wide fungal diversity for the first time and found that each habitat type has a distinct community, with biofilms being hotspots for aquatic fungi. The research highlights the importance of considering habitat heterogeneity when assessing fungal diversity in water bodies.
Researchers at Northwestern University have developed a technology platform that provides high-resolution representation of RNA folding during synthesis. This breakthrough allows for the study of RNA folding in unprecedented detail, potentially leading to discoveries in basic biology, gene expression, and disease.
A new study published in Geophysical Research Letters attributes the 2015 West Coast record-low snowpack to unusually high temperatures, not low precipitation. The researchers used a crowd-sourced supercomputer to analyze data and found that greenhouse gases contributed strongly to the risk of snow droughts in Oregon and Washington.
Researchers have developed a powerful screening method to identify drugs that more effectively target and kill pre-leukemic stem cells. By mimicking the bone marrow environment in a drug screening assay, they identified a compound called 2-methyoxyestradiol that reduces survival of pre-leukemic cells without affecting normal cells.
Researchers silenced SIRT2 to accelerate the degradation of Slug protein, reducing tumor growth and invasiveness in basal-like breast cancer cells. The study revealed a direct relationship between SIRT2, Slug stability, and malignant behavior, providing new insights into treating aggressive basal-like breast cancers.
Researchers found that specific IFNL3 and HLA-DPB1 genes are linked to a boost in immunity to hepatitis C after childbirth. Women carrying these genes experienced sharp declines in blood viral levels, improved T-cell activity, and better control of the virus after delivery.
A OU researcher received a 5-year $3 million grant to study the impact of e-cigarettes on smoking rates. The study will assess how effective different types of e-cigarettes are in helping smokers switch from cigarettes, and what impact switching has on cancer risk.
Researchers at the University at Buffalo have developed a new method for controlling light using one-third of the energy typically required. The asymmetric metawaveguide technology has the potential to lead to more powerful and energy-efficient computer chips and other optics-based technologies.
The leaf-mining pygmy moths and white eyecap moths have a rich evolutionary history that dates back to the early Cretaceous period, around 100 million years ago. A new classification system has been established based on DNA analysis, revealing three new genera in South and Central America.
A team of researchers from St. Jude Children's Research Hospital has completed a detailed map of the genomic landscape for core-binding factor acute myeloid leukemia (CBF-AML), revealing differences in mutations that contribute to its diversity.
Researchers at the University of Helsinki discovered that gene therapy stimulating blood vessel growth in the heart can alleviate cardiac atrophy caused by doxorubicin. The study found that this treatment prevented blood vessel rarefaction in mouse hearts, providing a potential solution for protecting patients from cardiotoxicity.
Researchers found industry sponsorship may be linked to more favorable study outcomes, but differences were not statistically significant. Insufficient evidence exists to quantify the impact of industry sponsorship on research quality and results.
A study has found a link between chlorhexidine exposure and antibiotic resistance in Klebsiella pneumoniae bacteria. The researchers discovered that certain strains of the bacteria could survive high concentrations of chlorhexidine and develop resistance to colistin, a last resort antibiotic.
A new study published in the Bulletin of the Seismological Society of America suggests that a handful of damaging earthquakes in the Los Angeles Basin may have been induced by oil production activities in the early 20th century. The researchers found links between earthquakes and significant oil production activities nearby, but note t...
A study published in the American Journal of Human Genetics identified a rare genetic variation in the RNF213 gene that is linked to an increased risk of intracranial aneurysm in French-Canadian individuals. The study found that 10% of patients with IA had at least one of these variants, compared to 0% in controls.
Scientists discover that heme molecule interferes with macrophage cytoskeleton, immobilizing them and preventing immune cells from eliminating bacteria. Quinine, an existing malaria medication, restores functionality of affected macrophages, paving the way for new treatment possibilities.
The Canadian Medical Association Journal argues that a new health accord for Canada should enable wholesale change in the federal-provincial relationship. The journal calls for flexible approach to allow for health system innovation and federal funding to improve the overall healthcare system without prespecified targets.
Archaeological remains in wetlands are threatened by rapid organic decay caused by acidic conditions. Researchers urge reevaluation of site preservation strategies and recommend urgent excavations to retrieve valuable artifacts.
Alexander N. Zelikin, a leading expert in medical polymer materials, has been honored with the 2016 Lundbeckfonden Research Prize for Young Scientists for his pioneering work on hydrogel biomaterials and enzyme-prodrug therapies. His research focuses on developing innovative solutions to complex medical issues.
New research from York University and Xi'an Jiaotong University finds that vaccinating against dengue fever can increase the spread of Zika. The study used mathematical modeling to investigate the effect of dengue vaccination on Zika outbreaks.
A new species of fungal disease, Curvularia malina, has been identified on short-cut Bermuda and Zoysia grasses in southern US golf courses. The disease can cause black spots and reduce turf aesthetic quality, but proper diagnosis and management practices can mitigate its impact.
A new study shows that a novel, nonsurgical approach can help 3 out of 4 adolescent athletes with vocal cord dysfunction (VCD) breathe better during exercise. The approach involves visual biofeedback, breathing techniques, and performance psychology training, and has been shown to improve breathing in 75% of patients.
A cross-sectional study of nearly 107,000 Medicare patients found that older black adults have a 30% increased likelihood of readmission compared to white counterparts. Increasing nurse-to-patient staffing ratios may help reduce these disparities by improving health outcomes for all patients, particularly high-risk groups.
Researchers have developed a new method to record brain activity in living mice, capturing the dynamic activity of thousands of neurons in three dimensions. The technique, known as 'light sculpting,' uses laser pulses to illuminate and analyze the activity of neurons within specific layers of the brain.
Researchers at the University of Houston have developed a novel method to induce superconductivity in calcium iron arsenide, a non-superconducting compound. This breakthrough demonstrates a concept proposed decades ago and offers a new direction for finding more efficient and less expensive superconductors.
Researchers can now gather broad-scale ecological data using micro-unmanned aerial vehicles (UAVs), or drones, eliminating traditional pitfalls. Drones amass vegetation data for monitoring habitat restoration efforts, rare plant populations, and agriculture, providing large amounts of information with minimal effort.
A genetic testing error led to the misdiagnosis of long QT syndrome in over 20 family members, resulting in one tragic death. The case highlights the importance of accurate interpretation and careful use of genetic testing to avoid such mistakes.
Schistosomiasis larvae employ a unique T-swimming style when moving against gravity, which helps them reach the water's surface. By understanding this biophysics, researchers hope to thwart infection and prevent re-infestation.
MIT engineers have transformed spinach plants into sensors that can detect explosives and wirelessly relay information to a handheld device. The carbon-nanotube-enhanced plants send an alert when sensing dangerous chemicals, making them ideal for environmental monitoring.
Researchers found that basketball players scored more points after being presented with death-related prompts, boosting their self-esteem and performance. Participants who thought about death performed 40% better in a second game and attempted more shots, suggesting a subconscious effort to regain a protective sense of self-esteem.
The BIONICS trial found that the ridaforolimus-eluting stent was non-inferior to the zotarolimus-eluting stent in terms of target lesion failure rates and had a low rate of stent thrombosis. The study, which enrolled over 1,900 patients, showed similar outcomes for cardiac death, TV-MI, and ID-TLR.
The ILUMIEN III trial found that optical coherence tomography-guided PCI resulted in similar minimal stent area compared to IVUS-guidance, while also showing improved stent expansion and acute procedural success compared to angiography-guidance. Untreated major dissections were more common after IVUS-guided PCI than OCT-guided PCI.
Research by Natalia Karelaia finds that social connectedness enhances the perceived effectiveness of actions, leading to increased social responsibility. Studies show that people who feel a sense of belonging and can make a difference are more likely to engage in environmentally conscious behaviors.
A team of researchers at Tokyo Medical and Dental University has identified a molecule called CD72 that prevents the immune system from mistakenly reacting to a component of the body's own cells. This breakthrough could lead to new treatments for systemic lupus erythematosus (SLE), a disease associated with inflammation of various organs.