Scientists at Princeton University have enhanced scanning tunneling microscopy to capture signals from the elusive Majorana fermion in iron wires on a lead crystal. The study detects a unique quantum property called spin, which distinguishes the particle from other quasi-particles and provides a signature of its existence.
A new study reveals that lead fishing tackle is the leading cause of mortality in adult common loons, resulting in 43% population decline over 24 years. The study found that jigs and sinkers accounted for most lead tackle objects ingested by loons.
The Van Andel Research Institute has been awarded two grants totaling $5.5 million to pursue clinical trials of epigenetic drugs combining with immunotherapies to enhance tumor response. The trials aim to test whether epigenetic therapies can reverse resistance to immunotherapy in lung and bladder cancers.
A study found that Canadian nephrologists generally recommend follow-up kidney evaluations for most patients with acute kidney injury but only a minority receive these evaluations. The disparity between recommendations and actual practices may be attributed to various factors, including patient age and pre-existing conditions.
Stanford researchers have found a new method to create bryostatin, a compound with potential for treating cancer, Alzheimer's disease, and HIV. The new synthetic supply will allow ongoing trials to continue testing its effectiveness.
A new study by UC Santa Cruz researchers rules out pre-European contact between Easter Island inhabitants and South Americans, leaving many questions unanswered about the island's population dynamics. The analysis of ancient DNA from skeletal remains found no evidence of gene flow between the two groups.
The European Menopause and Andropause Society recommends a daily calcium intake of 700-1200mg for postmenopausal women to reduce the risk of osteoporosis. Calcium-rich foods should be prioritized over supplements, as excessive intake may cause harm.
Researchers at Salk Institute have discovered that modified vitamin D can reprogram the tumor environment, allowing Keytruda to invade and destroy pancreatic tumors. The clinical trial aims to combine vitamin D with immunotherapy for a potential game-changer in pancreatic cancer treatment.
A new study published in Sustainable and Resilient Infrastructure predicts that warmer oceans will lead to higher wind speeds and larger storms, resulting in increased damage and financial losses due to hurricanes. The study estimates a 70% increase in hurricane-related financial loss by 2100 for coastal communities in South Carolina.
Researchers have created a 2-D material that can morph into a 3D structure and change color to blend in with its environment. The material mimics the skin of an octopus, featuring erector muscles that rapidly form shapes to achieve camouflage.
Researchers at IST Austria have identified a positive feedback loop between cell-cell contact formation and cell fate specification in zebrafish embryos. This loop, triggered by long-lasting contacts, leads to the specification of head mesoderm cells, while short-lasting contacts result in endoderm cells.
The University of Houston College of Nursing is using a high-fidelity mannequin to teach students about palliative care and end-of-life conversations. The mannequin, nicknamed
Researchers discovered an evolutionary conserved sequence motif in mammalian genomes that regulates class I odorant receptor genes, a novel mechanism of expression. The J element controls the selective expression of these genes, highlighting its importance in understanding gene regulation and disease.
A new study published in The Journal of Physiology found that pregnant women who sleep on their backs during late pregnancy may be at increased risk of late stillbirth. Fetal activity levels were lower when mothers slept on their backs, suggesting a potential link between maternal position and fetal wellbeing.
Researchers at MIT developed a new way to screen for genes that protect against specific diseases by adapting the CRISPR genome-editing system. The new technology identified genes that protect yeast cells from a protein associated with Parkinson's disease, which may also provide protective effects in human neurons.
Researchers identified new genomic regions associated with skin color variation in African populations, providing insights into DNA damage caused by UV radiation. The study found links between genes involved in repairing DNA damage and skin pigmentation, potentially shedding light on skin disease and cancer risk.
Researchers at Fred Hutchinson Cancer Center identified potential biomarkers and created algorithms to identify patients at risk of severe side effects from CAR T-cell therapy. The studies found that most patients with these toxicities experienced reversible or no harm, but severe cases were associated with endothelial cell activation.
A recent study published in Nature Communications has identified 52 previously unknown genes that play a crucial role in human hearing. The research used 'knock-out' mice to assess their hearing thresholds and found that these genes can lead to mild to severe hearing loss or difficulties at specific frequencies.
Researchers at the University of Minnesota have developed a promising approach called synthetic incompatibility to prevent interbreeding between genetically engineered and unaltered organisms. This technology effectively makes engineered organisms a separate species unable to produce viable offspring.
A recent study by Robinson et al. found that young men's 'bromances' are more emotionally satisfying than their romantic relationships with women. The researchers discovered that men felt less judged and more able to express emotions in their close male friendships compared to their girlfriends.
A QUT study found that humorous driver sleepiness advertisements can be ineffective due to drivers' expectations of shocking messages. Young Australian drivers prefer serious road safety topics over lighthearted approaches.
A study at San Diego International Airport found that signs encouraging stair use increased steps taken by 50% compared to sign-free days. The prompts appeared to nudge both regular and non-exercisers into taking the stairs, demonstrating a ripple effect in behavior.
A recent study published in PLOS ONE found that tropical tree roots account for almost 30% of the total biomass of young trees. The research also revealed diverse root architectures among species, with some sending large tap roots and others extending laterally just below the soil surface.
Researchers analyzed the structure and dynamics of riboswitches using optical single-molecule experiments. They found that the riboswitch fluctuates between different conformations, with SAM attachment accelerating structure changes to ensure quick gene expression shutdown.
A USC research team has identified a potential therapeutic target for liver cancer treatment: mitophagy, the removal of damaged mitochondria. This process can cause tumors to proliferate, but temporarily halting it may reduce cancer stem cell growth, leading to tumor regression.
Scientists at Goethe University Frankfurt reveal how correct molecular passports are selected by cells to avoid autoimmune diseases and cancer. The new discovery sheds light on the quality control of antigens, crucial for effective immune surveillance.
A new technique uses satellite-based remote-sensing to quantify plant metabolism by measuring solar-induced chlorophyll fluorescence. This correlation opens up applications for climate change and ecosystem monitoring, biodiversity conservation, and land management.
Researchers have discovered a new genetic signature for autism by analyzing the genomes of 516 autistic children and their families. The study found that individuals with autism are more likely to have multiple genetic variations, suggesting a complex interplay between genes in the development of the disorder.
The partnership aims to reduce environmental impact while developing innovative solutions for manufacturing petrochemical products. Researchers from ExxonMobil will collaborate with UH faculty and students on various projects, including studying catalysis and producing specialty chemicals.
A simpler early pregnancy test for cattle has improved animal welfare and food production by enabling pregnancy to be determined after just 25 days. This detection method has contributed to reduced animal costs, more efficient food production, and ultimately good human health.
The researchers have demonstrated the first laser cavity that can confine and propagate light in any shape imaginable, even pathways with sharp bends and angles. This new design could enable higher speed optical communication technologies.
Researchers found that mothers alter their voice timbre when speaking to infants, regardless of native language. This consistent shift enables computers to distinguish between infant- and adult-directed speech.
A new review in Marine Geology reveals that slightly warmer temperatures and moderate CO2 concentrations over 100,000 years ago led to dramatic superstorms and sea-level rise in the Bahamas and Bermuda. The study emphasizes that strong climate forcing is not required to yield major impacts on the ocean and ice caps.
A new UCSF-led study found that non-representative sampling in pediatric MRI images significantly distorted findings about brain development with age. The research team created a weighted version of the dataset to better reflect the US population, revealing faster-paced brain development and a back-to-front model of brain region develo...
Researchers at RIKEN discovered a way to prevent liver cancer spread by treating with a modified fucose sugar. The treatment disrupts biological pathways, blocking hepatoma cells from invading healthy liver cells and suppressing migration, but not proliferation.
A team of astronomers successfully traced a spiral arm on the far side of our Galaxy using radio interferometry and parallax measurements. They located the Scutum-Centaurus spiral arm as it passes around the far side and verified a new method to infer distances in this region.
Researchers at Northwestern University discovered that surface polarization in mixed media increases the attraction among rare earth elements. This finding could make rare earth recovery faster, easier, and less expensive. The study's results have implications for separating rare earths as well as other elements and nuclear waste removal.
Researchers at SDSU and partners have developed a new method to identify medicinal properties in unknown coral reef molecules. By analyzing molecular fingerprints, they can predict the potential therapeutic value of these molecules.
Monash University researchers identified PRMT1 as an enzyme essential for the immune system's ability to produce antibodies and clear infections. The discovery opens up new avenues for treating cancer and autoimmune diseases by targeting this enzyme.
The sea cucumber genome provides new insights into its ability to regenerate damaged body parts, including viscera, which can be regrown within weeks. The study identified specific genes that may contribute to this ability, offering potential avenues for regenerative medicine research.
A team of researchers at the University of Oregon has identified a universal pattern in protein motion, which could help pinpoint where proteins bind to other molecules. The study found that protein motion is governed by random energy fluctuations and a critical hydrogen-bonding network.
Astronomers using the VLBA have directly measured the distance to a star-forming region on the opposite side of the Milky Way, nearly doubling the previous record. This achievement allows for the accurate mapping of the Galaxy's structure and spiral arms.
Scientists have identified distinct neural signatures for explicit and implicit learning, which could guide the development of training techniques to mitigate learning and memory deficits. The findings may also help diagnose Alzheimer's disease at an earlier stage.
Scientists at the University of Illinois Chicago developed a multiscale model to study carbon dioxide conversion to carbon monoxide. The discovery could lead to efficient production of synthesis gas for large-scale energy applications.
Dr. Mark Stockman's research aims to create wave-guiding effects without magnets, using rotating nano-laser fields instead. This innovation has potential applications in the optical telecommunications industry and could make transistors more resilient to radiation damage.
Researchers discovered that high levels of cholesterol metabolism's byproduct 27HC facilitates breast cancer metastasis by hijacking specific immune cells. The study identifies 27HC as a potential drug target to inhibit its creation or actions, offering hope for effective therapies against this aggressive form of cancer.
A study has identified potential biomarkers to predict patients at increased risk of severe neurotoxicity after receiving CD19 CAR T-cell therapy. Patients with early onset of CRS were found to be more susceptible to severe neurotoxicity.
The inaugural SU2C Catalyst projects aim to explore new uses for powerful medicines in combination with other pharmaceutical company medicines, devices, and therapies. This program supports the selection of proposals by industry-specific sub-committees and significantly expedites the process of going from ideas to contracts to trials.
Researchers developed a bioinspired camera mimicking the mantis shrimp's eye to sense both color and polarization, enabling early cancer detection and decoding underwater communication channels. The camera uses silicon photodetectors and nanomaterials to replicate the mantis shrimp's visual system.
A new type of diabetes has been identified caused by a mutation in the RFX6 gene, leading to reduced insulin secretion and increased risk before age 20. GIP analogs may provide a novel treatment option for patients with this condition.
Researchers found that Twitter posts can predict football match outcomes by analyzing tone and sentiment, particularly after significant events like goals and red cards. Combining this information with betting market prices improves forecast accuracy, with a potential bettor earning an average return of 2.28%.
Researchers have made the largest study on genetic patterns and molecular changes in specific tissues, showing tens of thousands of variants with detectable effects. The studies also identified rare genetic variants contributing to extreme changes in cellular markers.
Researchers found over 30,000 publications reporting on misidentified HeLa cells, leading to potentially invalid research data and reproduced results. The study aims to raise awareness about the problem and promote caution when interpreting results.
Researchers found that people exposed to more sandfly bites had higher anti-saliva IgG immune responses and a greater risk of developing cutaneous leishmaniasis. This study provides insights into the mechanisms governing resistance or susceptibility to Leishmania parasite transmission.
Researchers found the common ancestor of apes to be small, probably weighing around 12 pounds, contrary to previous suggestions. This discovery has implications for understanding the evolution of human family trees and behavior such as suspensory locomotion.
A study published in Brain Stimulation found that transcranial direct current stimulation (tDCS) can improve endurance performance by decreasing perceived effort. The research, conducted at the University of Kent, used a placebo-controlled study to test the effects of tDCS on cycling time to task failure.
Researchers analyzed 50 years of rainfall data in a semi-arid drainage basin in Arizona, finding a decline in heavy rainfall events despite increased total rainfall. A new model simulates convective rainfall and shows less runoff from dryland basins under climate change.
Researchers discovered that the human protein APOBEC3G transforms its function from editing viral DNA to blocking HIV-1 replication when it forms a two-protein complex. This finding has implications for developing new anti-HIV drugs.
A study published in the Journal of Neuroscience reveals that imbalances in the regulation of GABA, a crucial neurotransmitter, can lead to developmental brain disorders such as autism and seizure disorders. The research offers new hope for developing treatments by identifying a potential molecular switch controlling GABA production.
A promising leprosy vaccine candidate, LepVax, is moving into human trials after years of research. The vaccine has been developed using cutting-edge technologies to induce protective responses against the disease.